Siderophores

Name

Siderophores

Accession Number

DBCAT001108

Description

Low-molecular-weight compounds produced by microorganisms that aid in the transport and sequestration of ferric iron. (The Encyclopedia of Molecular Biology, 1994)

Drugs

Drug	Drug Description
Deferoxamine	A chelating agent used to treat iron or aluminum toxicity and some blood transfusion dependent anemias.
Coprogen	Not Available
Cefiderocol	A cephalosporin antibiotic used in complicated urinary tract infections.

Drugs & Drug Targets

Drug	Target	Type
Deferoxamine	Xanthine dehydrogenase/oxidase	enzyme
Deferoxamine	Iron	target
Deferoxamine	Aluminum	target
Deferoxamine	Amyloid beta A4 protein	target
Coprogen	Iron(3+)-hydroxamate-binding protein FhuD	target
Cefiderocol	Penicillin-binding protein 3	target
Cefiderocol	Penicillin-binding protein 1A	target
Cefiderocol	Penicillin-binding protein 1B	target
Cefiderocol	Penicillin-binding protein 2	target
Cefiderocol	D-alanyl-D-alanine carboxypeptidase DacB	target
Cefiderocol	MexAB-OprM efflux system	transporter
Cefiderocol	Serum albumin	carrier
Cefiderocol	Catecholate siderophore receptor Fiu	transporter
Cefiderocol	Colicin I receptor	transporter
Cefiderocol	Putative outer membrane ferric siderophore receptor	transporter