Showing BioInteractions for Antihemophilic factor, human recombinant (DB00025)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Antihemophilic factor, human recombinant is a Coagulation factor X activator | ||
| 1 | Coagulation factor X activators | Albutrepenonacog alfa, Antihemophilic factor human, Coagulation Factor IX (Recombinant), Coagulation Factor IX Human, Coagulation factor VII human, Emicizumab, Lonoctocog alfa, Moroctocog alfa, Turoctocog alfa, Turoctocog alfa pegol |
| 2 | Coagulation factor X inhibitors | Antithrombin Alfa, Apixaban, Betrixaban, Edoxaban, Enoxaparin, Fondaparinux, Heparin, Nafamostat |
| 3 | Coagulation factor X antagonists | Bemiparin, Protein S human, Rivaroxaban |
| 4 | Coagulation factor X substrates | Prothrombin, Turoctocog alfa pegol |
| 5 | Coagulation factor X agonists | Anti-inhibitor coagulant complex, Kappadione, Nonacog beta pegol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Antihemophilic factor, human recombinant is a Phytanoyl-CoA dioxygenase, peroxisomal antagonist | ||
| 1 | Phytanoyl-CoA dioxygenase, peroxisomal antagonists | Lonoctocog alfa, Moroctocog alfa |
| 2 | Phytanoyl-CoA dioxygenase, peroxisomal cofactors | Ascorbic acid |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Antihemophilic factor, human recombinant is a Coagulation factor IX cofactor | ||
| 1 | Coagulation factor IX activators | Antihemophilic factor human, Coagulation factor VII human, Menadione, Turoctocog alfa, Turoctocog alfa pegol |
| 2 | Coagulation factor IX cofactors | Emicizumab, Lonoctocog alfa, Moroctocog alfa |
| 3 | Coagulation factor IX substrates | Anti-inhibitor coagulant complex |
| 4 | Coagulation factor IX agonists | Kappadione |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Antihemophilic factor, human recombinant is a Asialoglycoprotein receptor 2 binder | ||
| 1 | Asialoglycoprotein receptor 2 binders | Lonoctocog alfa, Moroctocog alfa |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Antihemophilic factor, human recombinant is a Prolow-density lipoprotein receptor-related protein 1 modulator | ||
| 1 | Prolow-density lipoprotein receptor-related protein 1 modulators | Lonoctocog alfa, Moroctocog alfa |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Antihemophilic factor, human recombinant is a Multiple coagulation factor deficiency protein 2 modulator | ||
| 1 | Multiple coagulation factor deficiency protein 2 modulators | Lonoctocog alfa, Moroctocog alfa |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Antihemophilic factor, human recombinant is a von Willebrand factor binder | ||
| 1 | von Willebrand factor binders | Antihemophilic factor (recombinant), PEGylated, Lonoctocog alfa, Moroctocog alfa, Turoctocog alfa pegol |
| 2 | von Willebrand factor bindings | Efmoroctocog alfa, Simoctocog alfa, Susoctocog alfa |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Antihemophilic factor, human recombinant is a Prothrombin activator | ||
| 1 | Prothrombin inhibitors | Antithrombin Alfa, Argatroban, Betrixaban, Bivalirudin, Conestat alfa, Dabigatran etexilate, Enoxaparin, Gabexate, Human C1-esterase inhibitor, Lepirudin, Nafamostat, Suramin, Thrombomodulin Alfa, Ximelagatran |
| 2 | Prothrombin activators | Lonoctocog alfa, Menadione, Moroctocog alfa |
| 3 | Prothrombin agonists | Anti-inhibitor coagulant complex, Kappadione |
| 4 | Prothrombin substrates | Anti-inhibitor coagulant complex |
| 5 | Prothrombin binders | Turoctocog alfa, Turoctocog alfa pegol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Antihemophilic factor, human recombinant is a Vitamin K-dependent protein C inactivator | ||
| 1 | Vitamin K-dependent protein C inhibitors | Sodium tetradecyl sulfate |
| 2 | Vitamin K-dependent protein C activators | Menadione |
| 3 | Vitamin K-dependent protein C inactivators | Lonoctocog alfa, Moroctocog alfa |
| 4 | Vitamin K-dependent protein C cofactors | Protein S human |
| 5 | Vitamin K-dependent protein C substrates | Antihemophilic factor human, Turoctocog alfa pegol |
| 6 | Vitamin K-dependent protein C agonists | Kappadione |