Showing BioInteractions for Biotin (DB00121)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Biotin is a Propionyl-CoA carboxylase beta chain, mitochondrial cofactor | ||
| 1 | Propionyl-CoA carboxylase beta chain, mitochondrial substrates | Valine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Biotin is a Biotin--protein ligase substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Biotin is a Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial cofactor | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Biotin is a Acetyl-CoA carboxylase 2 cofactor | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Biotin is a Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial cofactor | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Biotin is a Pyruvate carboxylase, mitochondrial cofactor | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Biotin is a Propionyl-CoA carboxylase alpha chain, mitochondrial cofactor | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Biotin is a Acetyl-CoA carboxylase 1 cofactor | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Biotin is a Cytochrome P450 1B1 inducer | ||
| 1 | Cytochrome P450 1B1 substrates | Amodiaquine, Caffeine, Dasatinib, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Flutamide, Melatonin, Progesterone, Tamoxifen, Testosterone, Testosterone undecanoate, Theophylline, Triclabendazole |
| 2 | Cytochrome P450 1B1 inhibitors | Cannabidiol, Daunorubicin, Doxorubicin, Ketoconazole, Medical Cannabis, Melatonin, Menadione, Mitoxantrone, Nabiximols, Paclitaxel, Propofol, Resveratrol, Tamoxifen |
| 3 | Cytochrome P450 1B1 inducers | Betamethasone, Budesonide, Doxorubicin, Hydrocortisone, Lansoprazole, Methylprednisolone, Omeprazole, Prednisolone phosphate, Prednisone, Primaquine, Triclocarban |
| 4 | Cytochrome P450 1B1 binders | Docetaxel |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Biotin is a Sodium-dependent multivitamin transporter substrate | ||
| 1 | Sodium-dependent multivitamin transporter substrates | Gabapentin enacarbil |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Biotin is a Sodium-coupled monocarboxylate transporter 1 substrate | ||
| 1 | Sodium-coupled monocarboxylate transporter 1 substrates | Gabapentin enacarbil, Inositol nicotinate |