Showing BioInteractions for Tryptophan (DB00150)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan--tRNA ligase, cytoplasmic inhibitor | ||
1 | Tryptophan--tRNA ligase, cytoplasmic inhibitors | Tryptophan |
2 | Tryptophan--tRNA ligase, cytoplasmic substrates | Tryptophan |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan--tRNA ligase inhibitor | ||
1 | Tryptophan--tRNA ligase inhibitors | Tryptophan |
2 | Tryptophan--tRNA ligase substrates | Tryptophan |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan--tRNA ligase, mitochondrial inhibitor | ||
1 | Tryptophan--tRNA ligase, mitochondrial inhibitors | Tryptophan |
2 | Tryptophan--tRNA ligase, mitochondrial substrates | Tryptophan |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan 2,3-dioxygenase substrate | ||
1 | Tryptophan 2,3-dioxygenase inhibitors | Nalidixic acid, Tolmetin |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Aromatic-L-amino-acid decarboxylase substrate | ||
1 | Aromatic-L-amino-acid decarboxylase cofactors | Pyridoxal phosphate |
2 | Aromatic-L-amino-acid decarboxylase inhibitors | Benserazide, Carbidopa, Cycloserine, Methyldopa |
3 | Aromatic-L-amino-acid decarboxylase substrates | Droxidopa, Fluorodopa (18F), Levodopa |
4 | Aromatic-L-amino-acid decarboxylase inducers | Amantadine, Flupentixol |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan--tRNA ligase substrate | ||
1 | Tryptophan--tRNA ligase inhibitors | Tryptophan |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan--tRNA ligase inhibitor | ||
1 | Tryptophan--tRNA ligase inhibitors | Tryptophan |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan--tRNA ligase, mitochondrial substrate | ||
1 | Tryptophan--tRNA ligase, mitochondrial inhibitors | Tryptophan |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan--tRNA ligase, mitochondrial inhibitor | ||
1 | Tryptophan--tRNA ligase, mitochondrial inhibitors | Tryptophan |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan 5-hydroxylase 1 substrate | ||
1 | Tryptophan 5-hydroxylase 1 cofactors | Sapropterin |
2 | Tryptophan 5-hydroxylase 1 antagonists | Telotristat ethyl |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan 5-hydroxylase 2 substrate | ||
1 | Tryptophan 5-hydroxylase 2 antagonists | Telotristat ethyl |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan--tRNA ligase, cytoplasmic substrate | ||
1 | Tryptophan--tRNA ligase, cytoplasmic inhibitors | Tryptophan |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Tryptophan--tRNA ligase, cytoplasmic inhibitor | ||
1 | Tryptophan--tRNA ligase, cytoplasmic inhibitors | Tryptophan |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Indoleamine 2,3-dioxygenase 1 substrate | ||
1 | Indoleamine 2,3-dioxygenase 1 substrates | Melatonin |
2 | Indoleamine 2,3-dioxygenase 1 inhibitors | Cannabidiol, Medical Cannabis, Nabiximols |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Monocarboxylate transporter 8 inhibitor | ||
1 | Monocarboxylate transporter 8 inhibitors | Levothyroxine, Liotrix, Tyrosine |
2 | Monocarboxylate transporter 8 substrates | Leucine, Thyroid, porcine |
Interacting Group | Interacting Drugs | |
---|---|---|
Tryptophan is a Monocarboxylate transporter 10 inhibitor | ||
1 | Monocarboxylate transporter 10 inhibitors | Alanine, Arginine, Asparagine, Aspartic acid, Cysteine, Cystine, D-Alanine, D-Leucine, D-Phenylalanine, D-Serine, D-Tryptophan, D-Tyrosine, Droxidopa, Glutamic acid, Glycine, Histidine, Isoleucine, L-Glutamine, Lactic acid, Leucine, Levodopa, Liothyronine, Liotrix, Lysine, Methionine, Phenylalanine, Proline, Pyruvic acid, Serine, Threonine, Tyrosine, Valine |
2 | Monocarboxylate transporter 10 substrates | 2-aminoisobutyric acid, beta-Alanine, D-Phenylalanine, Glutamic acid, Glycine, Histidine, Lactic acid, Lysine, Pyruvic acid |