Showing BioInteractions for Amphetamine (DB00182)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Amphetamine is a Sodium-dependent dopamine transporter negative modulator
1Sodium-dependent dopamine transporter inhibitors4-Methoxyamphetamine, Armodafinil, Benzatropine, Benzphetamine, Bupropion, Chloroprocaine, Chlorphenamine, Citalopram, Cocaine, Dexmethylphenidate, Diethylpropion, Diphenylpyraline, Duloxetine, Escitalopram, Etoperidone, Fencamfamine, Imipramine, Lisdexamfetamine, Mazindol, Meperidine, Methylphenidate, Modafinil, Nefazodone, Phenmetrazine, Phentermine, Procaine, Pseudoephedrine, Sertraline, Sibutramine, Trimipramine, Venlafaxine
2Sodium-dependent dopamine transporter negative modulatorsDextroamphetamine, Ephedra, Metamfetamine, Midomafetamine, MMDA
3Sodium-dependent dopamine transporter inducersDopamine
4Sodium-dependent dopamine transporter substratesCitalopram
5Sodium-dependent dopamine transporter bindersAmoxapine, Atomoxetine, Loxapine, Mianserin, Mirtazapine
6Sodium-dependent dopamine transporter antagonistsArmodafinil
Interacting GroupInteracting Drugs
Amphetamine is a Cocaine- and amphetamine-regulated transcript protein agonist
Interacting GroupInteracting Drugs
Amphetamine is a Trace amine-associated receptor 1 agonist
1Trace amine-associated receptor 1 agonistsDextroamphetamine, Metamfetamine, Propylhexedrine
Interacting GroupInteracting Drugs
Amphetamine is a Synaptic vesicular amine transporter inhibitor
1Synaptic vesicular amine transporter inhibitors4-Methoxyamphetamine, Deserpidine, Deutetrabenazine, Ephedra, Ephedrine, Isometheptene, Metamfetamine, Midomafetamine, MMDA, Rauwolfia serpentina root, Reserpine, Tetrabenazine
2Synaptic vesicular amine transporter inducersBenzphetamine, Dextroamphetamine
3Synaptic vesicular amine transporter bindersNorepinephrine
Interacting GroupInteracting Drugs
Amphetamine is a Sodium-dependent noradrenaline transporter stimulator
1Sodium-dependent noradrenaline transporter inhibitorsAmitriptyline, Amoxapine, Bupropion, Chlorphenamine, Citalopram, Clomipramine, Cocaine, Desipramine, Desvenlafaxine, Dexmethylphenidate, Dextromethorphan, Diethylpropion, Dopamine, Dosulepin, Doxepin, Duloxetine, Ergotamine, Escitalopram, Etoperidone, Ginkgo biloba, Imipramine, Ketamine, Levomilnacipran, Maprotiline, Mazindol, Meperidine, Methylphenidate, Mianserin, Milnacipran, Mirtazapine, Nefazodone, Nortriptyline, Orphenadrine, Paroxetine, Phenmetrazine, Phentermine, Protriptyline, Pseudoephedrine, Rauwolfia serpentina root, Reboxetine, Sibutramine, Tapentadol, Tramadol, Trimipramine, Venlafaxine, Viloxazine
2Sodium-dependent noradrenaline transporter partial agonistsGuanadrel
3Sodium-dependent noradrenaline transporter inducersDebrisoquin, Guanethidine
4Sodium-dependent noradrenaline transporter negative modulatorsDextroamphetamine, Ephedra, Metamfetamine, Midomafetamine, MMDA, Phendimetrazine
5Sodium-dependent noradrenaline transporter inverse agonistsEphedrine
6Sodium-dependent noradrenaline transporter substratesCitalopram, Droxidopa, Iobenguane, Iobenguane sulfate I-123, Norepinephrine
7Sodium-dependent noradrenaline transporter bindersLoxapine, Mirtazapine
8Sodium-dependent noradrenaline transporter antagonistsZotepine
Interacting GroupInteracting Drugs
Amphetamine is a Alpha adrenergic receptor agonist
1Alpha adrenergic receptor agonistsAranidipine, Dihydroergocornine, Dihydroergocristine, DL-Methylephedrine, Ergoloid mesylate, Indigotindisulfonic Acid, Mephentermine
2Alpha adrenergic receptor antagonistsDihydroergocornine, Dihydroergocristine, Ergoloid mesylate, Moxisylyte
Interacting GroupInteracting Drugs
Amphetamine is a Beta adrenergic receptor agonist
1Beta adrenergic receptor agonistsDihydroergocornine, Dihydroergocristine, DL-Methylephedrine, Ergoloid mesylate, Mephentermine
2Beta adrenergic receptor antagonistsBethanidine, Bufuralol, Dihydroergocornine, Dihydroergocristine, Ergoloid mesylate, Nortriptyline
3Beta adrenergic receptor bindersAmitriptyline, Trimipramine
4Beta adrenergic receptor inhibitorsOlanzapine
Interacting GroupInteracting Drugs
Amphetamine is a D(2) dopamine receptor binder
1D(2) dopamine receptor agonistsAmantadine, Apomorphine, Brexpiprazole, Bromocriptine, Cabergoline, Cariprazine, Dihydro-alpha-ergocryptine, Dopamine, Ergotamine, Ketamine, Levodopa, Lisuride, Memantine, Minaprine, Olanzapine, Pergolide, Pramipexole, Quinagolide, Ropinirole, Rotigotine
2D(2) dopamine receptor antagonistsAcepromazine, Acetophenazine, Alizapride, Amisulpride, Amoxapine, Aripiprazole, AS-8112, Asenapine, Blonanserin, Bromopride, Buspirone, Carphenazine, Chlorpromazine, Chlorprothixene, Clozapine, Domperidone, Doxepin, Droperidol, Etoperidone, Flupentixol, Fluphenazine, Fluspirilene, Haloperidol, Iloperidone, JNJ-37822681, Loxapine, Lurasidone, Melperone, Mesoridazine, Methotrimeprazine, Metoclopramide, Mianserin, Molindone, Nortriptyline, Olanzapine, Paliperidone, Perospirone, Perphenazine, Pimozide, Pipamperone, Pipotiazine, Prochlorperazine, Promazine, Promethazine, Propiomazine, Quetiapine, Raclopride, Remoxipride, Risperidone, Sertindole, Sulpiride, Tetrahydropalmatine, Thiethylperazine, Thioproperazine, Thioridazine, Thiothixene, Trifluoperazine, Triflupromazine, YKP-1358, Yohimbine, Ziprasidone, Zotepine, Zuclopenthixol
3D(2) dopamine receptor partial agonistsAripiprazole, Aripiprazole lauroxil, Brexpiprazole, Cariprazine, Ketamine, Sarizotan
4D(2) dopamine receptor inhibitorsLamotrigine, Mirtazapine, Tetrabenazine
5D(2) dopamine receptor bindersDesipramine, Imipramine, Maprotiline, Mirtazapine
6D(2) dopamine receptor blockersTiapride
Interacting GroupInteracting Drugs
Amphetamine is a Amine oxidase [flavin-containing] B inhibitor
1Amine oxidase [flavin-containing] B antagonistsMoclobemide, Phenelzine, Phentermine, Safinamide
2Amine oxidase [flavin-containing] B inhibitors4-Methoxyamphetamine, Amantadine, Ephedra, Furazolidone, Isocarboxazid, Linezolid, Metamfetamine, MMDA, Nandrolone decanoate, Nicotine, Pargyline, Phentermine, Rasagiline, Selegiline, Tranylcypromine, Zimelidine, Zonisamide
3Amine oxidase [flavin-containing] B substratesDopamine, Phenelzine, Sertraline
Interacting GroupInteracting Drugs
Amphetamine is a Sodium-dependent serotonin transporter binder
1Sodium-dependent serotonin transporter inhibitors4-Methoxyamphetamine, Amitriptyline, Amoxapine, Butriptyline, Chlorphenamine, Citalopram, Clomipramine, Cocaine, Desipramine, Desvenlafaxine, Dexfenfluramine, Dexmethylphenidate, Dextromethorphan, Dopamine, Dosulepin, Doxepin, Duloxetine, Escitalopram, Etoperidone, Fenfluramine, Fluoxetine, Fluvoxamine, Imipramine, Levomilnacipran, Mazindol, Methylphenidate, Mianserin, Milnacipran, Minaprine, Nefazodone, Nortriptyline, Paroxetine, Phentermine, Protriptyline, Pseudoephedrine, Sertraline, Sibutramine, Tapentadol, Tegaserod, Tramadol, Trazodone, Trimipramine, Venlafaxine, Vortioxetine
2Sodium-dependent serotonin transporter negative modulatorsEphedra, Metamfetamine, Midomafetamine, MMDA
3Sodium-dependent serotonin transporter substratesCitalopram, Tegaserod
4Sodium-dependent serotonin transporter bindersLoxapine, Mirtazapine
5Sodium-dependent serotonin transporter bindingsMeperidine
6Sodium-dependent serotonin transporter antagonistsButriptyline, Lorpiprazole, Zotepine
Interacting GroupInteracting Drugs
Amphetamine is a Monoamine oxidase inhibitor
1Monoamine oxidase inhibitorsProcaine, Procarbazine
2Monoamine oxidase cofactorsCopper
3Monoamine oxidase antagonistsMoclobemide
4Monoamine oxidase substratesEpinephrine, Rauwolfia serpentina root
Interacting GroupInteracting Drugs
Amphetamine is a Cytochrome P450 2D6 substrate
1Cytochrome P450 2D6 substrates4-Methoxyamphetamine, Acebutolol, Acetaminophen, Almotriptan, Alogliptin, Alprenolol, Aminophenazone, Amiodarone, Amitriptyline, Amoxapine, Amprenavir, Anisodamine, Antipyrine, Aprindine, Arformoterol, Aripiprazole, Aripiprazole lauroxil, Arotinolol, Artemether, Astemizole, Asunaprevir, Atenolol, Atomoxetine, Azelastine, Befunolol, Benzatropine, Benzyl alcohol, Bepridil, Betaxolol, Bevantolol, Bisoprolol, Bopindolol, Bortezomib, Brexpiprazole, Bucindolol, Bufuralol, Bupivacaine, Bupranolol, Buprenorphine, Bupropion, Buspirone, Caffeine, Captopril, Cariprazine, Carteolol, Carvedilol, Celiprolol, Cevimeline, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cilostazol, Cinnarizine, Citalopram, Clevidipine, Clomipramine, Clonidine, Cloranolol, Clozapine, Codeine, Cyclobenzaprine, Dacomitinib, Dapagliflozin, Dapoxetine, Darifenacin, Dasabuvir, Debrisoquin, Delavirdine, Desipramine, Deutetrabenazine, Dexchlorpheniramine maleate, Dexfenfluramine, Dextromethorphan, Dextropropoxyphene, Dihydrocodeine, Diltiazem, Diphenhydramine, Dolasetron, Domperidone, Donepezil, Dosulepin, Doxazosin, Doxepin, Doxorubicin, Dronedarone, Duloxetine, Elagolix, Eletriptan, Eliglustat, Enasidenib, Encainide, Enclomiphene, Encorafenib, Epanolol, Epinastine, Erlotinib, Esatenolol, Escitalopram, Esmirtazapine, Esmolol, Ethylmorphine, Fesoterodine, Flecainide, Flunarizine, Fluoxetine, Fluvastatin, Fluvoxamine, Formoterol, Fusidic Acid, Galantamine, Gefitinib, Haloperidol, Hydrocodone, Ibrutinib, Idarubicin, Iloperidone, Imatinib, Imipramine, Indenolol, Ipecac, Ipratropium, Ixazomib, Landiolol, Letermovir, Levobetaxolol, Levobunolol, Levomilnacipran, Lidocaine, Lisuride, Lofexidine, Loperamide, Loratadine, Lorcaserin, Lorpiprazole, Lysergic acid diethylamide, Maprotiline, Meperidine, Mephenytoin, Mepindolol, Mequitazine, Mesoridazine, Metamfetamine, Methadone, Methotrimeprazine, Methoxyflurane, Metipranolol, Metoprolol, Mexiletine, Mianserin, Midomafetamine, Minaprine, Mirabegron, Mirtazapine, Moclobemide, Morphine, Nadolol, Nateglinide, Nebivolol, Nefazodone, Netupitant, Nicergoline, Nicotine, Nifedipine, Nortriptyline, Olanzapine, Ondansetron, Opium, Oxprenolol, Oxycodone, Oxymorphone, Paliperidone, Palonosetron, Paroxetine, Pazopanib, Penbutolol, Pentamidine, Perhexiline, Perospirone, Perphenazine, Phenacetin, Phenformin, Pimozide, Pindolol, Piperazine, Pipotiazine, Pitolisant, Ponatinib, Practolol, Procainamide, Prochlorperazine, Progesterone, Promazine, Promethazine, Propacetamol, Propafenone, Propranolol, Protriptyline, Pseudoephedrine, Quetiapine, Quinine, Ranitidine, Remoxipride, Repinotan, Risperidone, Ritonavir, Rotigotine, Rucaparib, Rupatadine, Sertindole, Sertraline, Sildenafil, Simvastatin, Sotalol, Sparteine, Tafenoquine, Talinolol, Tamoxifen, Tamsulosin, Tapentadol, Tegaserod, Terfenadine, Tertatolol, Tesmilifene, Tetrabenazine, Theophylline, Thioridazine, Ticlopidine, Timolol, Tiotropium, Tipranavir, Tolterodine, Trabectedin, Tramadol, Trazodone, Trimipramine, Umeclidinium, Valbenazine, Venlafaxine, Vernakalant, Vilazodone, Vortioxetine, Yohimbine, Zolpidem, Zuclopenthixol
2Cytochrome P450 2D6 inhibitorsAbiraterone, Acebutolol, Amiodarone, Amitriptyline, Amlodipine, Amodiaquine, Antipyrine, Artenimol, Asenapine, Asunaprevir, Atomoxetine, Atorvastatin, Azelastine, Bicalutamide, Biperiden, Buprenorphine, Bupropion, Celecoxib, Cerivastatin, Chloroquine, Chlorphenamine, Chlorpromazine, Cholecalciferol, Ciclosporin, Cimetidine, Cimicifuga racemosa, Cinacalcet, Cisapride, Citalopram, Clemastine, Clinafloxacin, Clobazam, Clomipramine, Clotrimazole, Clozapine, Cobicistat, Cocaine, Curcumin, Dacomitinib, Darifenacin, Delavirdine, Deramciclane, Desipramine, Desloratadine, Dexfenfluramine, Dexmedetomidine, Dextropropoxyphene, Diacerein, Dimethyl sulfoxide, Diphenhydramine, Dosulepin, Doxepin, Dronedarone, Duloxetine, Efavirenz, Eliglustat, Enasidenib, Entacapone, Epinastine, Escitalopram, Etoricoxib, Felodipine, Fenfluramine, Fluoxetine, Fluphenazine, Fluvoxamine, Fusidic Acid, Gefitinib, Glycerol phenylbutyrate, Halofantrine, Haloperidol, Hydroxychloroquine, Hydroxyurea, Hydroxyzine, Imatinib, Imipramine, Indinavir, Indisulam, Iproniazid, Isavuconazole, Isoniazid, Itraconazole, Ketoconazole, Labetalol, Lansoprazole, Lenvatinib, Lercanidipine, Levosalbutamol, Lidocaine, Lomustine, Lopinavir, Loratadine, Lorcaserin, Lovastatin, Lumefantrine, Manidipine, Mefloquine, Melperone, Mepyramine, Methadone, Methazolamide, Methimazole, Methotrimeprazine, Metoclopramide, Metoprolol, Mibefradil, Miconazole, Midodrine, Midostaurin, Mifepristone, Mirabegron, Moclobemide, Naloxegol, Nefazodone, Nelfinavir, Nevirapine, Niacin, Nicardipine, Nicotinamide, Nilotinib, Nortriptyline, Olanzapine, Omeprazole, Ospemifene, Oxamniquine, Oxprenolol, Oxybutynin, Oxymetholone, Panobinostat, Paroxetine, Pazopanib, Peginterferon alfa-2b, Pergolide, Perhexiline, Perphenazine, Phenelzine, Phenylbutyric acid, Pindolol, Pipotiazine, Pitolisant, Primaquine, Proguanil, Promethazine, Propafenone, Propranolol, Quinidine, Quinine, Rabeprazole, Ranitidine, Ranolazine, Reboxetine, Rhein, Rifamycin, Rilpivirine, Risperidone, Ritanserin, Ritonavir, Rolapitant, Ropinirole, Rosiglitazone, Rotigotine, Rucaparib, Safinamide, Saquinavir, Selegiline, Sertraline, Sorafenib, Sparteine, St. John's Wort, Stiripentol, Sulconazole, Sulfanilamide, Sulfaphenazole, Tamoxifen, Tapentadol, Tegaserod, Temsirolimus, Terbinafine, Terfenadine, Thioridazine, Thiothixene, Ticagrelor, Ticlopidine, Tipranavir, Tranylcypromine, Tripelennamine, Trospium, Vemurafenib, Venlafaxine, Verapamil, Vernakalant, Vilazodone, Vinblastine, Vinorelbine, Ziprasidone
3Cytochrome P450 2D6 inducersDexamethasone, Enzalutamide, Fosphenytoin, Glutethimide, Griseofulvin, Oritavancin, Phenytoin, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Rifaximin
Interacting GroupInteracting Drugs
Amphetamine is a Cytochrome P450 2D6 inhibitor
1Cytochrome P450 2D6 substrates4-Methoxyamphetamine, Acebutolol, Acetaminophen, Almotriptan, Alogliptin, Alprenolol, Aminophenazone, Amiodarone, Amitriptyline, Amoxapine, Amprenavir, Anisodamine, Antipyrine, Aprindine, Arformoterol, Aripiprazole, Aripiprazole lauroxil, Arotinolol, Artemether, Astemizole, Asunaprevir, Atenolol, Atomoxetine, Azelastine, Befunolol, Benzatropine, Benzyl alcohol, Bepridil, Betaxolol, Bevantolol, Bisoprolol, Bopindolol, Bortezomib, Brexpiprazole, Bucindolol, Bufuralol, Bupivacaine, Bupranolol, Buprenorphine, Bupropion, Buspirone, Caffeine, Captopril, Cariprazine, Carteolol, Carvedilol, Celiprolol, Cevimeline, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cilostazol, Cinnarizine, Citalopram, Clevidipine, Clomipramine, Clonidine, Cloranolol, Clozapine, Codeine, Cyclobenzaprine, Dacomitinib, Dapagliflozin, Dapoxetine, Darifenacin, Dasabuvir, Debrisoquin, Delavirdine, Desipramine, Deutetrabenazine, Dexchlorpheniramine maleate, Dexfenfluramine, Dextromethorphan, Dextropropoxyphene, Dihydrocodeine, Diltiazem, Diphenhydramine, Dolasetron, Domperidone, Donepezil, Dosulepin, Doxazosin, Doxepin, Doxorubicin, Dronedarone, Duloxetine, Elagolix, Eletriptan, Eliglustat, Enasidenib, Encainide, Enclomiphene, Encorafenib, Epanolol, Epinastine, Erlotinib, Esatenolol, Escitalopram, Esmirtazapine, Esmolol, Ethylmorphine, Fesoterodine, Flecainide, Flunarizine, Fluoxetine, Fluvastatin, Fluvoxamine, Formoterol, Fusidic Acid, Galantamine, Gefitinib, Haloperidol, Hydrocodone, Ibrutinib, Idarubicin, Iloperidone, Imatinib, Imipramine, Indenolol, Ipecac, Ipratropium, Ixazomib, Landiolol, Letermovir, Levobetaxolol, Levobunolol, Levomilnacipran, Lidocaine, Lisuride, Lofexidine, Loperamide, Loratadine, Lorcaserin, Lorpiprazole, Lysergic acid diethylamide, Maprotiline, Meperidine, Mephenytoin, Mepindolol, Mequitazine, Mesoridazine, Metamfetamine, Methadone, Methotrimeprazine, Methoxyflurane, Metipranolol, Metoprolol, Mexiletine, Mianserin, Midomafetamine, Minaprine, Mirabegron, Mirtazapine, Moclobemide, Morphine, Nadolol, Nateglinide, Nebivolol, Nefazodone, Netupitant, Nicergoline, Nicotine, Nifedipine, Nortriptyline, Olanzapine, Ondansetron, Opium, Oxprenolol, Oxycodone, Oxymorphone, Paliperidone, Palonosetron, Paroxetine, Pazopanib, Penbutolol, Pentamidine, Perhexiline, Perospirone, Perphenazine, Phenacetin, Phenformin, Pimozide, Pindolol, Piperazine, Pipotiazine, Pitolisant, Ponatinib, Practolol, Procainamide, Prochlorperazine, Progesterone, Promazine, Promethazine, Propacetamol, Propafenone, Propranolol, Protriptyline, Pseudoephedrine, Quetiapine, Quinine, Ranitidine, Remoxipride, Repinotan, Risperidone, Ritonavir, Rotigotine, Rucaparib, Rupatadine, Sertindole, Sertraline, Sildenafil, Simvastatin, Sotalol, Sparteine, Tafenoquine, Talinolol, Tamoxifen, Tamsulosin, Tapentadol, Tegaserod, Terfenadine, Tertatolol, Tesmilifene, Tetrabenazine, Theophylline, Thioridazine, Ticlopidine, Timolol, Tiotropium, Tipranavir, Tolterodine, Trabectedin, Tramadol, Trazodone, Trimipramine, Umeclidinium, Valbenazine, Venlafaxine, Vernakalant, Vilazodone, Vortioxetine, Yohimbine, Zolpidem, Zuclopenthixol
2Cytochrome P450 2D6 inhibitorsAbiraterone, Acebutolol, Amiodarone, Amitriptyline, Amlodipine, Amodiaquine, Antipyrine, Artenimol, Asenapine, Asunaprevir, Atomoxetine, Atorvastatin, Azelastine, Bicalutamide, Biperiden, Buprenorphine, Bupropion, Celecoxib, Cerivastatin, Chloroquine, Chlorphenamine, Chlorpromazine, Cholecalciferol, Ciclosporin, Cimetidine, Cimicifuga racemosa, Cinacalcet, Cisapride, Citalopram, Clemastine, Clinafloxacin, Clobazam, Clomipramine, Clotrimazole, Clozapine, Cobicistat, Cocaine, Curcumin, Dacomitinib, Darifenacin, Delavirdine, Deramciclane, Desipramine, Desloratadine, Dexfenfluramine, Dexmedetomidine, Dextropropoxyphene, Diacerein, Dimethyl sulfoxide, Diphenhydramine, Dosulepin, Doxepin, Dronedarone, Duloxetine, Efavirenz, Eliglustat, Enasidenib, Entacapone, Epinastine, Escitalopram, Etoricoxib, Felodipine, Fenfluramine, Fluoxetine, Fluphenazine, Fluvoxamine, Fusidic Acid, Gefitinib, Glycerol phenylbutyrate, Halofantrine, Haloperidol, Hydroxychloroquine, Hydroxyurea, Hydroxyzine, Imatinib, Imipramine, Indinavir, Indisulam, Iproniazid, Isavuconazole, Isoniazid, Itraconazole, Ketoconazole, Labetalol, Lansoprazole, Lenvatinib, Lercanidipine, Levosalbutamol, Lidocaine, Lomustine, Lopinavir, Loratadine, Lorcaserin, Lovastatin, Lumefantrine, Manidipine, Mefloquine, Melperone, Mepyramine, Methadone, Methazolamide, Methimazole, Methotrimeprazine, Metoclopramide, Metoprolol, Mibefradil, Miconazole, Midodrine, Midostaurin, Mifepristone, Mirabegron, Moclobemide, Naloxegol, Nefazodone, Nelfinavir, Nevirapine, Niacin, Nicardipine, Nicotinamide, Nilotinib, Nortriptyline, Olanzapine, Omeprazole, Ospemifene, Oxamniquine, Oxprenolol, Oxybutynin, Oxymetholone, Panobinostat, Paroxetine, Pazopanib, Peginterferon alfa-2b, Pergolide, Perhexiline, Perphenazine, Phenelzine, Phenylbutyric acid, Pindolol, Pipotiazine, Pitolisant, Primaquine, Proguanil, Promethazine, Propafenone, Propranolol, Quinidine, Quinine, Rabeprazole, Ranitidine, Ranolazine, Reboxetine, Rhein, Rifamycin, Rilpivirine, Risperidone, Ritanserin, Ritonavir, Rolapitant, Ropinirole, Rosiglitazone, Rotigotine, Rucaparib, Safinamide, Saquinavir, Selegiline, Sertraline, Sorafenib, Sparteine, St. John's Wort, Stiripentol, Sulconazole, Sulfanilamide, Sulfaphenazole, Tamoxifen, Tapentadol, Tegaserod, Temsirolimus, Terbinafine, Terfenadine, Thioridazine, Thiothixene, Ticagrelor, Ticlopidine, Tipranavir, Tranylcypromine, Tripelennamine, Trospium, Vemurafenib, Venlafaxine, Verapamil, Vernakalant, Vilazodone, Vinblastine, Vinorelbine, Ziprasidone
3Cytochrome P450 2D6 inducersDexamethasone, Enzalutamide, Fosphenytoin, Glutethimide, Griseofulvin, Oritavancin, Phenytoin, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Rifaximin
Interacting GroupInteracting Drugs
Amphetamine is a Cytochrome P450 2A6 inhibitor
1Cytochrome P450 2A6 substratesAcetaminophen, Antipyrine, Arformoterol, Artesunate, Asunaprevir, Bupropion, Chlorzoxazone, Cinnarizine, Cisapride, Clomethiazole, Clozapine, Cyclophosphamide, Dapagliflozin, Dronabinol, Flunarizine, Flunitrazepam, Fluorouracil, Flurazepam, Formoterol, Halothane, Ifosfamide, Letrozole, Lidocaine, Lorcaserin, Methoxsalen, Methoxyflurane, Montelukast, Nevirapine, Nicotine, Nifedipine, Phenacetin, Progesterone, Selegiline, Sevoflurane, Tamoxifen, Tegafur, Tegafur-uracil, Tretinoin, Valproic Acid, Vortioxetine, Zidovudine
2Cytochrome P450 2A6 inhibitorsAmiodarone, Amlodipine, Azelastine, Azithromycin, Buprenorphine, Clofibrate, Clotrimazole, Desipramine, Fomepizole, Isoniazid, Ketoconazole, Letrozole, Memantine, Menadione, Methimazole, Methoxsalen, Metyrapone, Miconazole, Nicotine, Nilvadipine, Pilocarpine, Rosiglitazone, Seratrodast, Tranylcypromine
3Cytochrome P450 2A6 inducersAmobarbital, Dexamethasone, Eletriptan, Pentobarbital, Phenobarbital, Rifampicin, Valproic Acid
Interacting GroupInteracting Drugs
Amphetamine is a Solute carrier family 22 member 3 inhibitor
1Solute carrier family 22 member 3 inhibitorsCholine, Choline salicylate, Cimetidine, Clonidine, Colchicine, Desipramine, Dopamine, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Guanidine, Histamine, Imipramine, Irinotecan, Melphalan, Metamfetamine, Nicotine, Norepinephrine, Phenoxybenzamine, Prazosin, Procainamide, Progesterone, Vincristine
2Solute carrier family 22 member 3 substratesAdefovir Dipivoxil, Agmatine, Cimetidine, Guanidine, Lamivudine, Metformin, Norepinephrine, Oxaliplatin, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate
Interacting GroupInteracting Drugs
Amphetamine is a Solute carrier family 22 member 5 inhibitor
1Solute carrier family 22 member 5 inhibitorsAcetylcholine, Aldosterone, Aminohippuric acid, Ampicillin, Azidocillin, Benzylpenicillin, Cefadroxil, Cefalotin, Cefdinir, Cefepime, Cefixime, Cefradine, Ceftazidime, Cephalexin, Cephaloglycin, Choline, Choline salicylate, Cimetidine, Clonidine, Creatine, Cyclacillin, Dactinomycin, Desipramine, Diphenhydramine, Dopamine, Furosemide, Grepafloxacin, Guanidine, Histamine, L-Arginine, Lidocaine, Lomefloxacin, Metamfetamine, Niacin, Nicotine, Norepinephrine, Norfloxacin, Ofloxacin, Probenecid, Procainamide, Quinidine, Quinine, Sparfloxacin, Thiamine, Valproic Acid, Verapamil
2Solute carrier family 22 member 5 substratesIpratropium, Levocarnitine, Tiotropium