Showing BioInteractions for Sapropterin (DB00360)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting Group | Interacting Drugs | |
---|---|---|
Sapropterin is a Phenylalanine-4-hydroxylase cofactor | ||
1 | Phenylalanine-4-hydroxylase inhibitors | Droxidopa, Norepinephrine |
2 | Phenylalanine-4-hydroxylase inducers | Cupric sulfate |
Interacting Group | Interacting Drugs | |
---|---|---|
Sapropterin is a Nitric oxide synthase, endothelial cofactor | ||
1 | Nitric oxide synthase, endothelial inhibitors | Miconazole |
2 | Nitric oxide synthase, endothelial substrates | Doxorubicin |
3 | Nitric oxide synthase, endothelial agonists | Levamlodipine |
4 | Nitric oxide synthase, endothelial inducers | Levamlodipine, Pentaerythritol tetranitrate |
Interacting Group | Interacting Drugs | |
---|---|---|
Sapropterin is a Tyrosine 3-monooxygenase cofactor | ||
1 | Tyrosine 3-monooxygenase binders | Metyrosine, Phenylalanine, Tyrosine |
Interacting Group | Interacting Drugs | |
---|---|---|
Sapropterin is a Tryptophan 5-hydroxylase 1 cofactor | ||
1 | Tryptophan 5-hydroxylase 1 substrates | Tryptophan |
2 | Tryptophan 5-hydroxylase 1 antagonists | Telotristat ethyl |