Showing BioInteractions for Doxylamine (DB00366)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 2
Enzyme Mediated Interactions 1

	Interacting Group	Interacting Drugs
	Doxylamine is a Histamine H1 receptor antagonist
1	Histamine H1 receptor antagonists	Aceprometazine, Acrivastine, Alcaftadine, Alimemazine, Amitriptyline, Amoxapine, Antazoline, Aripiprazole, Aripiprazole lauroxil, Asenapine, Astemizole, Azatadine, Azelastine, Benzatropine, Benzquinamide, Bepotastine, Bilastine, Bromodiphenhydramine, Brompheniramine, Buclizine, Butriptyline, Carbinoxamine, Cariprazine, Cetirizine, Chlorcyclizine, Chloropyramine, Chlorpheniramine, Chlorpromazine, Chlorprothixene, Cinnarizine, Clemastine, Clofedanol, Clozapine, Cyclizine, Cyproheptadine, Desipramine, Desloratadine, Dexbrompheniramine, Dexchlorpheniramine maleate, Dimenhydrinate, Dimetindene, Diphenhydramine, Diphenylpyraline, Dosulepin, Doxepin, Emedastine, Epinastine, Fexofenadine, Flunarizine, Iloperidone, Imipramine, Isothipendyl, Ketotifen, Lamotrigine, Levocabastine, Levocetirizine, Loratadine, Lorpiprazole, Maprotiline, Meclizine, Mepyramine, Mequitazine, Methdilazine, Methotrimeprazine, Mianserin, Mirtazapine, Nortriptyline, Olanzapine, Olopatadine, Orphenadrine, Paliperidone, Phenindamine, Pizotifen, Prochlorperazine, Promazine, Promethazine, Propiomazine, Quetiapine, Risperidone, Rupatadine, Terfenadine, Tesmilifene, Thonzylamine, Trazodone, Trimipramine, Tripelennamine, Triprolidine, Ziprasidone, Zuclopenthixol
2	Histamine H1 receptor inverse agonists	Esmirtazapine, Hydroxyzine, Perospirone, Pheniramine
3	Histamine H1 receptor agonists	Betahistine, Histamine, Tolazoline
4	Histamine H1 receptor inhibitors	Escitalopram, Levocetirizine, Paroxetine
5	Histamine H1 receptor binders	Citalopram, Loxapine

	Interacting Group	Interacting Drugs
	Doxylamine is a Muscarinic acetylcholine receptor antagonist
1	Muscarinic acetylcholine receptor antagonists	Amoxapine, Etoperidone, Metixene, Nortriptyline, Propiomazine, Revefenacin
2	Muscarinic acetylcholine receptor binders	Cinnarizine, Ketamine, Meperidine, Trimipramine
3	Muscarinic acetylcholine receptor ligands	Amitriptyline
4	Muscarinic acetylcholine receptor inhibitors	Paroxetine

	Interacting Group	Interacting Drugs
	Doxylamine is a CYP2B protein inducer
1	CYP2B protein inhibitors	Nefazodone
2	CYP2B protein inducers	Fluoxetine, Sertraline
3	CYP2B protein substrates	Moxidectin