Showing BioInteractions for Dipivefrin (DB00449)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 5

	Interacting Group	Interacting Drugs
	Dipivefrin is a Alpha-2A adrenergic receptor agonist
1	Alpha-2A adrenergic receptor agonists	4-Methoxyamphetamine, Amitriptyline, Apomorphine, Apraclonidine, Benzphetamine, Brimonidine, Bromocriptine, Clonidine, Dexmedetomidine, Dihydroergotamine, DL-Methylephedrine, Droxidopa, Ephedra sinica root, Epinephrine, Guanabenz, Guanfacine, Lofexidine, Metamfetamine, Moxonidine, Naphazoline, Norepinephrine, Oxymetazoline, Pramipexole, Pseudoephedrine, Racepinephrine, Xylometazoline
2	Alpha-2A adrenergic receptor antagonists	Amitriptyline, Amoxapine, Aripiprazole, Asenapine, Cabergoline, Carvedilol, Celiprolol, Clozapine, Dronedarone, Fenoldopam, Methotrimeprazine, Mianserin, Mirtazapine, Nefazodone, Paliperidone, Periciazine, Phenoxybenzamine, Phentolamine, Pipamperone, Pirlindole, Pizotifen, Quetiapine, Tolazoline, Trazodone, Yohimbine, Ziprasidone, Zuclopenthixol
3	Alpha-2A adrenergic receptor partial agonists	Ergotamine, Oxymetazoline
4	Alpha-2A adrenergic receptor binders	Loxapine, Prazosin
5	Alpha-2A adrenergic receptor inhibitors	Lamotrigine

	Interacting Group	Interacting Drugs
	Dipivefrin is a Cholinesterase substrate
1	Cholinesterase inhibitors	Ambenonium, Aprotinin, Bambuterol, Betaine, Capsaicin, Chlorpromazine, Cinchocaine, Cisplatin, Decamethonium, Demecarium, Diethylcarbamazine, Echothiophate, Edrophonium, Galantamine, Hexafluronium, Isoflurophate, Ketamine, Malathion, Mechlorethamine, Mefloquine, Methylphosphinic Acid, Neostigmine, Nizatidine, Pancuronium, Pegvisomant, Perindopril, Phenserine, Pipecuronium, Procainamide, Procaine, Profenamine, Ramipril, Regramostim, Rivastigmine, Sulpiride, Tacrine, Terbutaline, Thiotepa, Tretamine, Triflupromazine
2	Cholinesterase substrates	Aclidinium, Bambuterol, Benzonatate, Butamben, Butyrylthiocholine, Chloroprocaine, Clevidipine, Cocaine, Cyclopentolate, Doxacurium, Ephedrine, Irinotecan, Mirabegron, Moxisylyte, Oxybuprocaine, Procaine, Propacetamol, Sar9, Met (O2)11-Substance P, Succinylcholine, Trimethaphan, Tubocurarine
3	Cholinesterase ligands	Butyric Acid, Ethyl dihydrogen phosphate, Phosphorylisopropane
4	Cholinesterase antagonists	Pyridostigmine
5	Cholinesterase activators	Pralidoxime
6	Cholinesterase inducers	Chlorphenesin, Donepezil, Pentagastrin, Triamcinolone

	Interacting Group	Interacting Drugs
	Dipivefrin is a Beta-2 adrenergic receptor agonist
1	Beta-2 adrenergic receptor antagonists	Alprenolol, Arotinolol, Asenapine, Atenolol, Betaxolol, Bevantolol, Bisoprolol, Bupranolol, Carteolol, Carvedilol, Desipramine, Labetalol, Levobunolol, Metipranolol, Metoprolol, Nadolol, Nebivolol, Oxprenolol, Penbutolol, Propafenone, Propranolol, Sotalol, Timolol
2	Beta-2 adrenergic receptor agonists	Albuterol, Arbutamine, Arformoterol, Bambuterol, Bedoradrine, Celiprolol, Clenbuterol, Dobutamine, Doxofylline, Droxidopa, Ephedra sinica root, Ephedrine, Epinephrine, Etafedrine, Fenoterol, Formoterol, Indacaterol, Isoetharine, Isoprenaline, Levosalbutamol, Norepinephrine, Olodaterol, Orciprenaline, Phenylpropanolamine, Pirbuterol, Procaterol, Protokylol, Racepinephrine, Ritodrine, Salmeterol, Terbutaline, Vilanterol
3	Beta-2 adrenergic receptor partial agonists	Acebutolol, Bopindolol, Penbutolol, Pindolol, Pseudoephedrine
4	Beta-2 adrenergic receptor binders	Cabergoline
5	Beta-2 adrenergic receptor ligands	Aripiprazole

	Interacting Group	Interacting Drugs
	Dipivefrin is a Alpha-1A adrenergic receptor agonist
1	Alpha-1A adrenergic receptor agonists	4-Methoxyamphetamine, Apraclonidine, Benzphetamine, Bromocriptine, Cirazoline, Clonidine, Droxidopa, Ephedrine, Epinephrine, Ergometrine, Isometheptene, Lofexidine, Metaraminol, Methoxamine, Midodrine, Naphazoline, Norepinephrine, Pergolide, Phendimetrazine, Phenylephrine, Pseudoephedrine, Racepinephrine, Tetryzoline, Xylometazoline
2	Alpha-1A adrenergic receptor antagonists	Acepromazine, Alfuzosin, Amitriptyline, Amoxapine, Aripiprazole, Aripiprazole lauroxil, Asenapine, Bevantolol, Bromocriptine, Carvedilol, Chlorpromazine, Clozapine, Dapiprazole, Doxazosin, Doxepin, Dronedarone, Droperidol, Flupentixol, Iloperidone, Imipramine, Indoramin, Methotrimeprazine, Nefazodone, Nicardipine, Nicergoline, Niguldipine, Nortriptyline, Olanzapine, Paliperidone, Phenoxybenzamine, Phentolamine, Pizotifen, Prazosin, Promazine, Propiomazine, Propiverine, Quinidine, Risperidone, Silodosin, Tamsulosin, Terazosin, Thioproperazine, Thioridazine, Tolazoline, Trazodone, Trifluoperazine, Trimipramine, Verapamil, Ziprasidone, Zuclopenthixol
3	Alpha-1A adrenergic receptor partial agonists	Ergotamine, Oxymetazoline, Xylometazoline
4	Alpha-1A adrenergic receptor potentiators	Carvedilol
5	Alpha-1A adrenergic receptor inhibitors	Amitriptyline, Fenoldopam, Lamotrigine
6	Alpha-1A adrenergic receptor binders	Cabergoline, Loxapine

	Interacting Group	Interacting Drugs
	Dipivefrin is a Acetylcholinesterase inhibitor
1	Acetylcholinesterase inhibitors	Ambenonium, Decamethonium, Demecarium, Donepezil, Edrophonium, Ephedrine, Galantamine, Gallamine triethiodide, Huperzine A, Isoflurophate, Itopride, Mefloquine, Methantheline, Minaprine, Neostigmine, Physostigmine, Pyridostigmine, Ranitidine, Rivastigmine, Tacrine, Tubocurarine, Tyrothricin
2	Acetylcholinesterase antagonists	Dimetacrine, Pyridostigmine
3	Acetylcholinesterase activators	Pralidoxime
4	Acetylcholinesterase substrates	Carbamoylcholine