Showing BioInteractions for Oxaliplatin (DB00526)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a Glutathione S-transferase theta-1 substrate | ||
1 | Glutathione S-transferase theta-1 substrates | Carboplatin, Cisplatin, Etoposide |
2 | Glutathione S-transferase theta-1 inducers | Polaprezinc |
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a Metallothionein-1A substrate | ||
1 | Metallothionein-1A substrates | Carboplatin, Cisplatin |
2 | Metallothionein-1A binders | Zinc chloride, Zinc sulfate, unspecified form |
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a Metallothionein-2 substrate | ||
1 | Metallothionein-2 substrates | Carboplatin, Cisplatin |
2 | Metallothionein-2 cofactors | Zinc chloride, Zinc sulfate, unspecified form |
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a Myeloperoxidase substrate | ||
1 | Myeloperoxidase inhibitors | AB192, Aminosalicylic acid, Bivalirudin, Calcipotriol, Capsaicin, Cariporide, Cefdinir, Elafin, Melatonin, Nabumetone, Octreotide, Propylthiouracil, Tiopronin, Tolmetin |
2 | Myeloperoxidase substrates | Carboplatin, Cysteamine, Dapsone, Melatonin, Ticlopidine |
3 | Myeloperoxidase inducers | Cefaclor, Cisplatin, Urethane |
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a Superoxide dismutase [Cu-Zn] substrate | ||
1 | Superoxide dismutase [Cu-Zn] inducers | alpha-Tocopherol succinate, D-alpha-Tocopherol acetate, Polaprezinc, Vitamin E |
2 | Superoxide dismutase [Cu-Zn] substrates | Cisplatin |
3 | Superoxide dismutase [Cu-Zn] inhibitors | Cannabidiol, Carboplatin, Medical Cannabis, Nabiximols |
4 | Superoxide dismutase [Cu-Zn] cofactors | Copper, Zinc chloride, Zinc sulfate, unspecified form |
5 | Superoxide dismutase [Cu-Zn] ligands | Zinc acetate |
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a Glutathione S-transferase P substrate | ||
1 | Glutathione S-transferase P inhibitors | alpha-Tocopherol succinate, Clomipramine, Curcumin, D-alpha-Tocopherol acetate, Etacrynic acid, Exisulind, Vitamin E |
2 | Glutathione S-transferase P substrates | Acetaminophen, Busulfan, Carboplatin, Chlorambucil, Cisplatin, Etoposide |
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a Glutathione S-transferase Mu 1 substrate | ||
1 | Glutathione S-transferase Mu 1 substrates | Acetaminophen, Azathioprine, Busulfan, Carboplatin, Cisplatin, Isosorbide mononitrate |
2 | Glutathione S-transferase Mu 1 inhibitors | Chloroquine, Curcumin |
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a NAD(P)H dehydrogenase [quinone] 1 substrate | ||
1 | NAD(P)H dehydrogenase [quinone] 1 inhibitors | Cannabidiol, Dicoumarol |
2 | NAD(P)H dehydrogenase [quinone] 1 inducers | alpha-Tocopherol succinate, D-alpha-Tocopherol acetate, Vitamin E |
3 | NAD(P)H dehydrogenase [quinone] 1 substrates | Carboplatin, Cisplatin, Doxorubicin, Phenytoin |
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a High affinity copper uptake protein 1 substrate | ||
1 | High affinity copper uptake protein 1 substrates | Carboplatin, Cisplatin, Copper |
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a Solute carrier family 22 member 3 substrate | ||
1 | Solute carrier family 22 member 3 inhibitors | Choline, Choline salicylate, Cimetidine, Clonidine, Desipramine, Dopamine, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Formoterol, Guanidine, Histamine, Imipramine, Irinotecan, Linagliptin, Melphalan, Metamfetamine, Nicotine, Norepinephrine, Phenoxybenzamine, Prazosin, Procainamide, Progesterone, Salmeterol, Vincristine |
2 | Solute carrier family 22 member 3 substrates | Adefovir dipivoxil, Agmatine, Amphetamine, Cimetidine, Guanidine, Lamivudine, Metformin, Norepinephrine, Sulpiride, Testosterone cypionate, Testosterone enanthate |
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a Copper-transporting ATPase 2 substrate | ||
1 | Copper-transporting ATPase 2 substrates | Carboplatin, Cisplatin, Copper |
Interacting Group | Interacting Drugs | |
---|---|---|
Oxaliplatin is a Copper-transporting ATPase 1 substrate | ||
1 | Copper-transporting ATPase 1 substrates | Carboplatin, Cisplatin, Copper |