Showing BioInteractions for Propylthiouracil (DB00550)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Propylthiouracil is a Thyroid peroxidase inhibitor | ||
| 1 | Thyroid peroxidase inhibitors | 2-mercaptobenzothiazole, Carbimazole, Methimazole |
| 2 | Thyroid peroxidase substrates | Iodine, Methimazole |
| 3 | Thyroid peroxidase weak inhibitors | Triclosan |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Propylthiouracil is a Myeloperoxidase inhibitor | ||
| 1 | Myeloperoxidase inhibitors | AB192, Aminosalicylic acid, Bivalirudin, Calcipotriol, Capsaicin, Cariporide, Cefdinir, Elafin, Melatonin, Nabumetone, Octreotide, Tiopronin, Tolmetin |
| 2 | Myeloperoxidase substrates | Carboplatin, Cysteamine, Dapsone, Melatonin, Oxaliplatin, Ticlopidine |
| 3 | Myeloperoxidase inducers | Cefaclor, Cisplatin, Urethane |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Propylthiouracil is a Dopamine beta-hydroxylase inhibitor | ||
| 1 | Dopamine beta-hydroxylase ligands | Dopamine |
| 2 | Dopamine beta-hydroxylase cofactors | Ascorbic acid, Copper |
| 3 | Dopamine beta-hydroxylase inhibitors | Capsaicin, Disulfiram |
| 4 | Dopamine beta-hydroxylase substrates | Dopamine |
| 5 | Dopamine beta-hydroxylase inducers | Corticorelin |