Showing BioInteractions for Adenosine (DB00640)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Adenosine receptor A3 agonist | ||
| 1 | Adenosine receptor A3 antagonists | Aminophylline, Caffeine, Fostamatinib |
| 2 | Adenosine receptor A3 inhibitors | Enprofylline |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Adenosine receptor A1 agonist | ||
| 1 | Adenosine receptor A1 antagonists | Aminophylline, Caffeine, Dyphylline, Istradefylline, Naxifylline, Oxtriphylline, Theobromine, Theophylline |
| 2 | Adenosine receptor A1 agonists | Gabapentin |
| 3 | Adenosine receptor A1 inhibitors | Enprofylline, Lamotrigine |
| 4 | Adenosine receptor A1 activators | Cannabidiol |
| 5 | Adenosine receptor A1 stimulators | Tramadol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Adenosine receptor A2a agonist | ||
| 1 | Adenosine receptor A2a antagonists | 8-chlorotheophylline, Caffeine, Doxofylline, Dyphylline, Istradefylline, Mefloquine, Oxtriphylline, Theobromine, Theophylline |
| 2 | Adenosine receptor A2a agonists | Pentoxifylline, Regadenoson |
| 3 | Adenosine receptor A2a inhibitors | Enprofylline, Lamotrigine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Adenosine receptor A2b agonist | ||
| 1 | Adenosine receptor A2b antagonists | Caffeine, Enprofylline, Theophylline |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Adenosine deaminase substrate | ||
| 1 | Adenosine deaminase inhibitors | Dipyridamole, Edetate calcium disodium anhydrous, Edetate disodium anhydrous, Edetic acid, Erdosteine, Pentostatin, Theophylline |
| 2 | Adenosine deaminase substrates | Nelarabine, Vidarabine |
| 3 | Adenosine deaminase inducers | Theophylline |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Adenosine kinase substrate | ||
| 1 | Adenosine kinase substrates | Abacavir, ATP |
| 2 | Adenosine kinase activators | Ribavirin |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Adenylate kinase isoenzyme 1 substrate | ||
| 1 | Adenylate kinase isoenzyme 1 substrates | Tenofovir, Tenofovir alafenamide |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Nucleoside diphosphate kinase A substrate | ||
| 1 | Nucleoside diphosphate kinase A substrates | Adefovir dipivoxil, Lamivudine, Sofosbuvir, Tenofovir, Tenofovir alafenamide |
| 2 | Nucleoside diphosphate kinase A inhibitors | Zinc chloride, Zinc sulfate, unspecified form |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Nucleoside diphosphate kinase B substrate | ||
| 1 | Nucleoside diphosphate kinase B substrates | Adefovir dipivoxil, Lamivudine, Tenofovir, Tenofovir alafenamide |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Purine nucleoside phosphorylase substrate | ||
| 1 | Purine nucleoside phosphorylase inducers | Cladribine |
| 2 | Purine nucleoside phosphorylase substrates | Didanosine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Xanthine dehydrogenase/oxidase substrate | ||
| 1 | Xanthine dehydrogenase/oxidase inhibitors | Allopurinol, Carvedilol, Chlorphenesin, Deferoxamine, Eniluracil, Febuxostat, Spermine |
| 2 | Xanthine dehydrogenase/oxidase substrates | Azathioprine, Daunorubicin, Doxorubicin, Favipiravir, Inosine, Isosorbide mononitrate, Menadione, Mercaptopurine, NADH, Nitrofural, Porfiromycin, Procarbazine, Pyrazinamide |
| 3 | Xanthine dehydrogenase/oxidase conversion inhibitors | Trifluoperazine |
| 4 | Xanthine dehydrogenase/oxidase inducers | Aldesleukin, Carboplatin, Cisplatin, Inosine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Equilibrative nucleoside transporter 1 substrate | ||
| 1 | Equilibrative nucleoside transporter 1 inhibitors | Cannabidiol, Fostamatinib, Medical Cannabis, Nabiximols, Troglitazone |
| 2 | Equilibrative nucleoside transporter 1 substrates | Cytarabine, Fludarabine, Fluorouracil, Gemcitabine, Mercaptopurine, Ribavirin, Tegafur-uracil, Trifluridine |
| 3 | Equilibrative nucleoside transporter 1 inducers | Pemetrexed |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Equilibrative nucleoside transporter 2 substrate | ||
| 1 | Equilibrative nucleoside transporter 2 substrates | Azathioprine, Mercaptopurine, Tegafur-uracil, Trifluridine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Equilibrative nucleoside transporter 3 substrate | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Equilibrative nucleoside transporter 4 substrate | ||
| 1 | Equilibrative nucleoside transporter 4 substrates | Metformin |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Sodium/nucleoside cotransporter 1 substrate | ||
| 1 | Sodium/nucleoside cotransporter 1 substrates | Decitabine, Tegafur-uracil, Trifluridine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Sodium/nucleoside cotransporter 2 substrate | ||
| 1 | Sodium/nucleoside cotransporter 2 substrates | Mercaptopurine, Tegafur-uracil |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Adenosine is a Gap junction alpha-1 protein substrate | ||