Showing BioInteractions for Ethotoin (DB00754)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ethotoin is a Sodium channel protein type 5 subunit alpha inhibitor | ||
| 1 | Sodium channel protein type 5 subunit alpha inhibitors | Ajmaline, Aprindine, Cinchocaine, Disopyramide, Dronedarone, Encainide, Flecainide, Fosphenytoin, Hexylcaine, Indecainide, Isavuconazole, Lidocaine, Mephenytoin, Mexiletine, Moricizine, Phenytoin, Prilocaine, Procainamide, Propafenone, Quinidine, Quinidine barbiturate, Riluzole, Tocainide, Zonisamide |
| 2 | Sodium channel protein type 5 subunit alpha antagonists | Benzonatate |
| 3 | Sodium channel protein type 5 subunit alpha blockers | Vernakalant |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ethotoin is a Nuclear receptor subfamily 1 group I member 2 activator | ||
| 1 | Nuclear receptor subfamily 1 group I member 2 binders | Docetaxel, Estradiol |
| 2 | Nuclear receptor subfamily 1 group I member 2 agonists | Dexamethasone, Dexamethasone acetate, Erlotinib, Ethinylestradiol, Nifedipine, Rifampicin, Rifaximin, Rilpivirine |
| 3 | Nuclear receptor subfamily 1 group I member 2 inducers | Paclitaxel |
| 4 | Nuclear receptor subfamily 1 group I member 2 activators | Carbamazepine, Clotrimazole, Mephenytoin, Methylphenobarbital, Pentobarbital, Phenobarbital, Prasterone, Quercetin, Ritonavir, Sulfinpyrazone, Troleandomycin |
| 5 | Nuclear receptor subfamily 1 group I member 2 partial agonists | Bezafibrate, Clonazepam, Econazole, Fenofibrate, Fenofibric acid, Miconazole, Myrrh, Oxiconazole |
| 6 | Nuclear receptor subfamily 1 group I member 2 antagonists | Ketoconazole |
| 7 | Nuclear receptor subfamily 1 group I member 2 suppressors | Dovitinib |