Showing BioInteractions for Progabide (DB00837)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Progabide is a Gamma-aminobutyric acid receptor subunit alpha-1 agonist
1Gamma-aminobutyric acid receptor subunit alpha-1 potentiatorsAdinazolam, Amobarbital, Aprobarbital, Barbital, Bromazepam, Butalbital, Butobarbital, Cinolazepam, Clotiazepam, Diazepam, Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione, Dihydroquinidine barbiturate, Estazolam, Eszopiclone, Fludiazepam, Flurazepam, Halazepam, Heptabarbital, Hexobarbital, Ketazolam, Metharbital, Methylphenobarbital, Midazolam, Nitrazepam, Oxazepam, Pentobarbital, Phenobarbital, Prazepam, Primidone, Quazepam, Quinidine barbiturate, Secobarbital, Talbutal, Temazepam, Thiopental, Triazolam, Zaleplon, Zopiclone
2Gamma-aminobutyric acid receptor subunit alpha-1 agonistsEthanol, Etizolam, Etomidate, Flunitrazepam, Glutethimide, Isoflurane, Meprobamate, Methoxyflurane, Methyprylon, Sevoflurane, Thiamylal, Topiramate, Zolpidem
3Gamma-aminobutyric acid receptor subunit alpha-1 antagonistsAmoxapine, Flumazenil, Methohexital, Picrotoxin
4Gamma-aminobutyric acid receptor subunit alpha-1 ligandsAlprazolam
5Gamma-aminobutyric acid receptor subunit alpha-1 negative modulatorsGinkgo biloba
6Gamma-aminobutyric acid receptor subunit alpha-1 activatorsCarisoprodol
7Gamma-aminobutyric acid receptor subunit alpha-1 modulatorsCarisoprodol
8Gamma-aminobutyric acid receptor subunit alpha-1 positive allosteric modulatorsLormetazepam
Interacting GroupInteracting Drugs
Progabide is a Gamma-aminobutyric acid type B receptor subunit 1 agonist
1Gamma-aminobutyric acid type B receptor subunit 1 agonistsArbaclofen, Arbaclofen Placarbil, Baclofen, Taurine, Vigabatrin