Showing BioInteractions for Oxazepam (DB00842)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 2
Enzyme Mediated Interactions 3

	Interacting Group	Interacting Drugs
	Oxazepam is a GABA(A) Receptor positive allosteric modulator
1	GABA(A) Receptor positive allosteric modulators	1,2-Benzodiazepine, Adinazolam, Alprazolam, Bentazepam, Brexanolone, Bromazepam, Brotizolam, Butabarbital, Butalbital, Camazepam, Chlordiazepoxide, Cinazepam, Cinolazepam, Clobazam, Clonazepam, Clorazepic acid, Clotiazepam, Cloxazolam, Delorazepam, Desflurane, Diazepam, Doxefazepam, Estazolam, Eszopiclone, Ethchlorvynol, Ethyl loflazepate, Etizolam, Etomidate, Flumazenil, Flunitrazepam, Flurazepam, Glutethimide, Halazepam, Halothane, Isoflurane, Ketazolam, Loprazolam, Lorazepam, Lormetazepam, Medazepam, Meprobamate, Metharbital, Methoxyflurane, Methyprylon, Mexazolam, Midazolam, Nitrazepam, Nordazepam, Oxazepam acetate, Pentobarbital, Pinazepam, Prazepam, Primidone, Propofol, Quazepam, Remimazolam, Sevoflurane, Stiripentol, Talbutal, Temazepam, Triazolam
2	GABA(A) Receptor potentiators	Enflurane
3	GABA(A) Receptor binders	Amoxapine, Memantine
4	GABA(A) Receptor antagonists	Apalutamide, Lamotrigine, Prasterone, Thiocolchicoside
5	GABA(A) Receptor agonists	Stiripentol, Taurine
6	GABA(A) Receptor inducers	Lamotrigine
7	GABA(A) Receptor inhibitors	Medroxyprogesterone acetate

	Interacting Group	Interacting Drugs
	Oxazepam is a GABA(A) Receptor Benzodiazepine Binding Site ligand
1	GABA(A) Receptor Benzodiazepine Binding Site partial agonists	Adipiplon
2	GABA(A) Receptor Benzodiazepine Binding Site ligands	1,2-Benzodiazepine, 5,7,2′-trihydroxy-6,8-dimethoxyflavone, Adinazolam, Alprazolam, Bentazepam, Bromazepam, Brotizolam, Camazepam, Chlordiazepoxide, Cinazepam, Cinolazepam, Clobazam, Clonazepam, Clorazepic acid, Clotiazepam, Cloxazolam, Delorazepam, Diazepam, Doxefazepam, Estazolam, Ethyl loflazepate, Etizolam, Flunitrazepam, Flurazepam, Halazepam, Ketazolam, Loprazolam, Lorazepam, Lormetazepam, Medazepam, Mexazolam, Midazolam, Nitrazepam, Nordazepam, Oxazepam acetate, Pinazepam, Prazepam, Quazepam, Remimazolam, Temazepam, Triazolam
3	GABA(A) Receptor Benzodiazepine Binding Site inhibitors	Lamotrigine, Olanzapine

	Interacting Group	Interacting Drugs
	Oxazepam is a UDP-glucuronosyltransferase 2B15 substrate
1	UDP-glucuronosyltransferase 2B15 substrates	Acetaminophen, Dabigatran etexilate, Delafloxacin, Dextromethorphan, Enasidenib, Ezetimibe, Formoterol, Lorazepam, Morphine, Propacetamol, Troglitazone, Valproic acid
2	UDP-glucuronosyltransferase 2B15 inducers	Estradiol

	Interacting Group	Interacting Drugs
	Oxazepam is a UDP-glucuronosyltransferase 2B7 substrate
1	UDP-glucuronosyltransferase 2B7 substrates	Acemetacin, Ambrisentan, Anastrozole, Artenimol, Artesunate, Bempedoic acid, Carbamazepine, Carvedilol, Cenobamate, Codeine, Dabigatran etexilate, Dapagliflozin, Dexibuprofen, Dextromethorphan, Diclofenac, Empagliflozin, Enasidenib, Epirubicin, Ertugliflozin, Ethinylestradiol, Etodolac, Ezetimibe, Febuxostat, Flurbiprofen, Fluvastatin, Formoterol, Gemfibrozil, Hydromorphone, Ibuprofen, Indomethacin, Ketorolac, Labetalol, Letrozole, Losartan, Lovastatin, Loxoprofen, Mitiglinide, Morphine, Mycophenolate mofetil, Mycophenolic acid, Nalmefene, Naproxen, Osilodrostat, Pitavastatin, Silodosin, Simvastatin, Suprofen, Tamoxifen, Tapentadol, Troglitazone, Vadimezan, Valproic acid, Zaltoprofen, Zidovudine
2	UDP-glucuronosyltransferase 2B7 inhibitors	Chenodeoxycholic acid, Dovitinib, Flunitrazepam, Indomethacin, Ketoconazole, Mefenamic acid, Umifenovir
3	UDP-glucuronosyltransferase 2B7 inducers	Phenobarbital

	Interacting Group	Interacting Drugs
	Oxazepam is a UDP-glucuronosyltransferase 1-9 substrate
1	UDP-glucuronosyltransferase 1-9 substrates	Acetaminophen, Ambrisentan, Artenimol, Artesunate, Ataluren, Cabotegravir, Canagliflozin, Dabigatran etexilate, Dapagliflozin, Dexibuprofen, Diclofenac, Dolutegravir, Empagliflozin, Enasidenib, Entacapone, Ertugliflozin, Ethinylestradiol, Etodolac, Ezogabine, Febuxostat, Fenofibrate, Flurbiprofen, Formoterol, Fostamatinib, Gavestinel, Gemfibrozil, Glasdegib, Haloperidol, Ibuprofen, Indomethacin, Irinotecan, Ketobemidone, Labetalol, Lumiracoxib, Mycophenolate mofetil, Mycophenolic acid, Naproxen, Nateglinide, Oxymetazoline, Phenytoin, Propacetamol, Propofol, Regorafenib, Seratrodast, Sorafenib, Tapentadol, Topiroxostat, Troglitazone, Umifenovir, Vadimezan, Valdecoxib, Valproic acid, Vericiguat, Zileuton
2	UDP-glucuronosyltransferase 1-9 inhibitors	Deferasirox, Diflunisal, Eltrombopag, Fosphenytoin, Isavuconazole, Mefenamic acid, Methylene blue, Morniflumate, Niflumic acid, Phenytoin, Regorafenib, Rifampicin, Sorafenib, Umifenovir