Showing BioInteractions for Pseudoephedrine (DB00852)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Alpha-1A adrenergic receptor agonist
1	Alpha-1A adrenergic receptor agonists	4-Methoxyamphetamine, Apraclonidine, Benzphetamine, Bromocriptine, Cirazoline, Clonidine, Dipivefrin, Droxidopa, Ephedrine, Epinephrine, Ergometrine, Isometheptene, Lofexidine, Metaraminol, Methoxamine, Midodrine, Naphazoline, Norepinephrine, Pergolide, Phendimetrazine, Phenylephrine, Racepinephrine, Tetryzoline, Xylometazoline
2	Alpha-1A adrenergic receptor antagonists	Acepromazine, Alfuzosin, Amitriptyline, Amoxapine, Aripiprazole, Aripiprazole lauroxil, Asenapine, Bevantolol, Bromocriptine, Carvedilol, Chlorpromazine, Clozapine, Dapiprazole, Doxazosin, Doxepin, Dronedarone, Droperidol, Flupentixol, Iloperidone, Imipramine, Indoramin, Methotrimeprazine, Nefazodone, Nicardipine, Nicergoline, Niguldipine, Nortriptyline, Olanzapine, Paliperidone, Phenoxybenzamine, Phentolamine, Pizotifen, Prazosin, Promazine, Propiomazine, Propiverine, Quinidine, Risperidone, Silodosin, Tamsulosin, Terazosin, Thioproperazine, Thioridazine, Tolazoline, Trazodone, Trifluoperazine, Trimipramine, Verapamil, Ziprasidone, Zuclopenthixol
3	Alpha-1A adrenergic receptor partial agonists	Ergotamine, Oxymetazoline, Xylometazoline
4	Alpha-1A adrenergic receptor potentiators	Carvedilol
5	Alpha-1A adrenergic receptor inhibitors	Amitriptyline, Fenoldopam, Lamotrigine
6	Alpha-1A adrenergic receptor binders	Cabergoline, Loxapine

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Alpha-2A adrenergic receptor agonist
1	Alpha-2A adrenergic receptor agonists	4-Methoxyamphetamine, Amitriptyline, Apomorphine, Apraclonidine, Benzphetamine, Brimonidine, Bromocriptine, Clonidine, Dexmedetomidine, Dihydroergotamine, Dipivefrin, DL-Methylephedrine, Droxidopa, Ephedra sinica root, Epinephrine, Guanabenz, Guanfacine, Lofexidine, Metamfetamine, Moxonidine, Naphazoline, Norepinephrine, Oxymetazoline, Pramipexole, Racepinephrine, Xylometazoline
2	Alpha-2A adrenergic receptor antagonists	Amitriptyline, Amoxapine, Aripiprazole, Asenapine, Cabergoline, Carvedilol, Celiprolol, Clozapine, Dronedarone, Fenoldopam, Methotrimeprazine, Mianserin, Mirtazapine, Nefazodone, Paliperidone, Periciazine, Phenoxybenzamine, Phentolamine, Pipamperone, Pirlindole, Pizotifen, Quetiapine, Tolazoline, Trazodone, Yohimbine, Ziprasidone, Zuclopenthixol
3	Alpha-2A adrenergic receptor partial agonists	Ergotamine, Oxymetazoline
4	Alpha-2A adrenergic receptor binders	Loxapine, Prazosin
5	Alpha-2A adrenergic receptor inhibitors	Lamotrigine

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Beta-2 adrenergic receptor partial agonist
1	Beta-2 adrenergic receptor antagonists	Alprenolol, Arotinolol, Asenapine, Atenolol, Betaxolol, Bevantolol, Bisoprolol, Bupranolol, Carteolol, Carvedilol, Desipramine, Labetalol, Levobunolol, Metipranolol, Metoprolol, Nadolol, Nebivolol, Oxprenolol, Penbutolol, Propafenone, Propranolol, Sotalol, Timolol
2	Beta-2 adrenergic receptor agonists	Albuterol, Arbutamine, Arformoterol, Bambuterol, Bedoradrine, Celiprolol, Clenbuterol, Dipivefrin, Dobutamine, Doxofylline, Droxidopa, Ephedra sinica root, Ephedrine, Epinephrine, Etafedrine, Fenoterol, Formoterol, Indacaterol, Isoetharine, Isoprenaline, Levosalbutamol, Norepinephrine, Olodaterol, Orciprenaline, Phenylpropanolamine, Pirbuterol, Procaterol, Protokylol, Racepinephrine, Ritodrine, Salmeterol, Terbutaline, Vilanterol
3	Beta-2 adrenergic receptor partial agonists	Acebutolol, Bopindolol, Penbutolol, Pindolol
4	Beta-2 adrenergic receptor binders	Cabergoline
5	Beta-2 adrenergic receptor ligands	Aripiprazole

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Beta-1 adrenergic receptor agonist
1	Beta-1 adrenergic receptor antagonists	Alprenolol, Arotinolol, Asenapine, Atenolol, Betaxolol, Bevantolol, Bisoprolol, Bupranolol, Carvedilol, Celiprolol, Dronedarone, Esmolol, Labetalol, Levobetaxolol, Levobunolol, Metipranolol, Metoprolol, Nadolol, Nebivolol, Oxprenolol, Penbutolol, Practolol, Propafenone, Propranolol, Ranolazine, Sotalol, Terbutaline, Timolol
2	Beta-1 adrenergic receptor agonists	Albuterol, Arbutamine, Clenbuterol, DL-Methylephedrine, Dobutamine, Droxidopa, Ephedra sinica root, Ephedrine, Epinephrine, Fenoterol, Formoterol, Isoetharine, Isoprenaline, Norepinephrine, Phenylpropanolamine, Pirbuterol, Racepinephrine
3	Beta-1 adrenergic receptor partial agonists	Acebutolol, Bopindolol, Carteolol, Penbutolol, Pindolol, Xamoterol
4	Beta-1 adrenergic receptor binders	Cabergoline, Loxapine
5	Beta-1 adrenergic receptor ligands	Aripiprazole, Vortioxetine
6	Beta-1 adrenergic receptor inverse agonists	Salmeterol
7	Beta-1 adrenergic receptor inhibitors	Lamotrigine

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Beta-1 adrenergic receptor partial agonist
1	Beta-1 adrenergic receptor antagonists	Alprenolol, Arotinolol, Asenapine, Atenolol, Betaxolol, Bevantolol, Bisoprolol, Bupranolol, Carvedilol, Celiprolol, Dronedarone, Esmolol, Labetalol, Levobetaxolol, Levobunolol, Metipranolol, Metoprolol, Nadolol, Nebivolol, Oxprenolol, Penbutolol, Practolol, Propafenone, Propranolol, Ranolazine, Sotalol, Terbutaline, Timolol
2	Beta-1 adrenergic receptor agonists	Albuterol, Arbutamine, Clenbuterol, DL-Methylephedrine, Dobutamine, Droxidopa, Ephedra sinica root, Ephedrine, Epinephrine, Fenoterol, Formoterol, Isoetharine, Isoprenaline, Norepinephrine, Phenylpropanolamine, Pirbuterol, Racepinephrine
3	Beta-1 adrenergic receptor partial agonists	Acebutolol, Bopindolol, Carteolol, Penbutolol, Pindolol, Xamoterol
4	Beta-1 adrenergic receptor binders	Cabergoline, Loxapine
5	Beta-1 adrenergic receptor ligands	Aripiprazole, Vortioxetine
6	Beta-1 adrenergic receptor inverse agonists	Salmeterol
7	Beta-1 adrenergic receptor inhibitors	Lamotrigine

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Sodium-dependent dopamine transporter inhibitor
1	Sodium-dependent dopamine transporter inhibitors	4-Methoxyamphetamine, Armodafinil, Benzatropine, Benzphetamine, Bupropion, Chloroprocaine, Chlorpheniramine, Cocaine, Desvenlafaxine, Dexmethylphenidate, Diethylpropion, Diphenylpyraline, Duloxetine, Escitalopram, Etoperidone, Fencamfamin, Imipramine, Mazindol, Meperidine, Methylphenidate, Modafinil, Nefazodone, Phenmetrazine, Phentermine, Procaine, Pseudoephedrine, Sertraline, Sibutramine, Trimipramine, Venlafaxine
2	Sodium-dependent dopamine transporter negative modulators	Amphetamine, Dextroamphetamine, Ephedra sinica root, Metamfetamine, Midomafetamine, MMDA
3	Sodium-dependent dopamine transporter binders	Amoxapine, Loxapine, Mianserin, Sertraline
4	Sodium-dependent dopamine transporter inducers	Dopamine
5	Sodium-dependent dopamine transporter antagonists	Armodafinil
6	Sodium-dependent dopamine transporter modulators	Aripiprazole

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Sodium-dependent noradrenaline transporter inhibitor
1	Sodium-dependent noradrenaline transporter inhibitors	Amitriptyline, Amoxapine, Atomoxetine, Benzatropine, Bupropion, Chlorpheniramine, Clomipramine, Cocaine, Cyclobenzaprine, Desipramine, Desvenlafaxine, Dexmethylphenidate, Dextromethorphan, Diethylpropion, Dopamine, Dosulepin, Doxepin, Duloxetine, Escitalopram, Etoperidone, Ginkgo biloba, Imipramine, Ketamine, Levomilnacipran, Maprotiline, Mazindol, Meperidine, Methylphenidate, Mianserin, Milnacipran, Nefazodone, Netarsudil, Nortriptyline, Orphenadrine, Paroxetine, Phenmetrazine, Phentermine, Procaine, Protriptyline, Pseudoephedrine, Rauwolfia serpentina root, Reboxetine, Sertraline, Sibutramine, Tapentadol, Tramadol, Trimipramine, Venlafaxine, Viloxazine
2	Sodium-dependent noradrenaline transporter partial agonists	Guanadrel
3	Sodium-dependent noradrenaline transporter inducers	Debrisoquine, Guanethidine
4	Sodium-dependent noradrenaline transporter negative modulators	Dextroamphetamine, Ephedra sinica root, Metamfetamine, Midomafetamine, MMDA, Phendimetrazine
5	Sodium-dependent noradrenaline transporter inverse agonists	Ephedrine
6	Sodium-dependent noradrenaline transporter substrates	Droxidopa, Iobenguane, Iobenguane sulfate I-123, Norepinephrine, Nortriptyline
7	Sodium-dependent noradrenaline transporter binders	Loxapine
8	Sodium-dependent noradrenaline transporter stimulators	Amphetamine
9	Sodium-dependent noradrenaline transporter blockers	Vortioxetine
10	Sodium-dependent noradrenaline transporter antagonists	Zotepine

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Sodium-dependent serotonin transporter inhibitor
1	Sodium-dependent serotonin transporter inhibitors	4-Methoxyamphetamine, Amitriptyline, Amoxapine, Benzatropine, Butriptyline, Chlorpheniramine, Citalopram, Clomipramine, Cocaine, Cyclobenzaprine, Desipramine, Desvenlafaxine, Dexfenfluramine, Dexmethylphenidate, Dextromethorphan, Dopamine, Dosulepin, Doxepin, Duloxetine, Escitalopram, Etoperidone, Fenfluramine, Fluoxetine, Fluvoxamine, Imipramine, Levomilnacipran, Lumateperone, Mazindol, Mianserin, Milnacipran, Minaprine, Mirtazapine, Nefazodone, Nortriptyline, Paroxetine, Phentermine, Procaine, Protriptyline, Pseudoephedrine, Sertraline, Sibutramine, Tapentadol, Tegaserod, Tramadol, Trazodone, Trimipramine, Venlafaxine, Vilazodone, Vortioxetine
2	Sodium-dependent serotonin transporter binders	Amphetamine, Atomoxetine, Loxapine, Sertraline
3	Sodium-dependent serotonin transporter negative modulators	Ephedra sinica root, Metamfetamine, Midomafetamine, MMDA
4	Sodium-dependent serotonin transporter substrates	Fenfluramine, Mirtazapine, Tegaserod
5	Sodium-dependent serotonin transporter bindings	Meperidine
6	Sodium-dependent serotonin transporter antagonists	Butriptyline, Lorpiprazole, Zotepine
7	Sodium-dependent serotonin transporter modulators	Aripiprazole

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Nuclear factor of activated T-cells, cytoplasmic 1 inhibitor

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Tumor necrosis factor inhibitor
1	Tumor necrosis factor inhibitors	Amrinone, Chloroquine, Infliximab, Polaprezinc, Pomalidomide, Thalidomide
2	Tumor necrosis factor neutralizers	Certolizumab pegol
3	Tumor necrosis factor antagonists	Epinephrine, Glycyrrhizic acid
4	Tumor necrosis factor agonists	Epinephrine, Foreskin fibroblast (neonatal), Foreskin keratinocyte (neonatal)
5	Tumor necrosis factor inducers	Bryostatin 1

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Nuclear factor NF-kappa-B p105 subunit inhibitor
1	Nuclear factor NF-kappa-B p105 subunit antagonists	Thalidomide, Triflusal

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a activator protein 1 inhibitor

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Interleukin-2 inhibitor
1	Interleukin-2 inhibitors	Cefazolin

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Amine oxidase [flavin-containing] A inhibitor
1	Amine oxidase [flavin-containing] A inhibitors	4-Methoxyamphetamine, Brofaromine, Capsaicin, Ephedra sinica root, Furazolidone, Iproniazid, Isocarboxazid, Linezolid, Metamfetamine, Minaprine, MMDA, Moclobemide, Nandrolone decanoate, Nicotine, Pargyline, Phenylpropanolamine, Pirlindole, Propranolol, Safinamide, Selegiline, Tedizolid, Tedizolid phosphate, Toloxatone, Tranylcypromine, Ubrogepant, Zimelidine, Zonisamide
2	Amine oxidase [flavin-containing] A antagonists	Moclobemide, Phenelzine, Phentermine, Pirlindole, Toloxatone
3	Amine oxidase [flavin-containing] A substrates	Almotriptan, Bicifadine, Bufotenine, Dopamine, Eravacycline, Naratriptan, Phenelzine, Phenylephrine, Rizatriptan, Sertraline, Sumatriptan, Zolmitriptan
4	Amine oxidase [flavin-containing] A cofactors	Riboflavin
5	Amine oxidase [flavin-containing] A inducers	Oxymetholone, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate
6	Amine oxidase [flavin-containing] A binders	Flortaucipir F-18

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Sodium-dependent noradrenaline transporter inhibitor
1	Sodium-dependent noradrenaline transporter inhibitors	Amitriptyline, Amoxapine, Atomoxetine, Benzatropine, Bupropion, Chlorpheniramine, Clomipramine, Cocaine, Cyclobenzaprine, Desipramine, Desvenlafaxine, Dexmethylphenidate, Dextromethorphan, Diethylpropion, Dopamine, Dosulepin, Doxepin, Duloxetine, Escitalopram, Etoperidone, Ginkgo biloba, Imipramine, Ketamine, Levomilnacipran, Maprotiline, Mazindol, Meperidine, Methylphenidate, Mianserin, Milnacipran, Nefazodone, Netarsudil, Nortriptyline, Orphenadrine, Paroxetine, Phenmetrazine, Phentermine, Procaine, Protriptyline, Pseudoephedrine, Rauwolfia serpentina root, Reboxetine, Sertraline, Sibutramine, Tapentadol, Tramadol, Trimipramine, Venlafaxine, Viloxazine
2	Sodium-dependent noradrenaline transporter partial agonists	Guanadrel
3	Sodium-dependent noradrenaline transporter inducers	Debrisoquine, Guanethidine
4	Sodium-dependent noradrenaline transporter negative modulators	Dextroamphetamine, Ephedra sinica root, Metamfetamine, Midomafetamine, MMDA, Phendimetrazine
5	Sodium-dependent noradrenaline transporter inverse agonists	Ephedrine
6	Sodium-dependent noradrenaline transporter substrates	Droxidopa, Iobenguane, Iobenguane sulfate I-123, Norepinephrine, Nortriptyline
7	Sodium-dependent noradrenaline transporter binders	Loxapine
8	Sodium-dependent noradrenaline transporter stimulators	Amphetamine
9	Sodium-dependent noradrenaline transporter blockers	Vortioxetine
10	Sodium-dependent noradrenaline transporter antagonists	Zotepine

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Sodium-dependent dopamine transporter inhibitor
1	Sodium-dependent dopamine transporter inhibitors	4-Methoxyamphetamine, Armodafinil, Benzatropine, Benzphetamine, Bupropion, Chloroprocaine, Chlorpheniramine, Cocaine, Desvenlafaxine, Dexmethylphenidate, Diethylpropion, Diphenylpyraline, Duloxetine, Escitalopram, Etoperidone, Fencamfamin, Imipramine, Mazindol, Meperidine, Methylphenidate, Modafinil, Nefazodone, Phenmetrazine, Phentermine, Procaine, Pseudoephedrine, Sertraline, Sibutramine, Trimipramine, Venlafaxine
2	Sodium-dependent dopamine transporter negative modulators	Amphetamine, Dextroamphetamine, Ephedra sinica root, Metamfetamine, Midomafetamine, MMDA
3	Sodium-dependent dopamine transporter binders	Amoxapine, Loxapine, Mianserin, Sertraline
4	Sodium-dependent dopamine transporter inducers	Dopamine
5	Sodium-dependent dopamine transporter antagonists	Armodafinil
6	Sodium-dependent dopamine transporter modulators	Aripiprazole

	Interacting Group	Interacting Drugs
	Pseudoephedrine is a Sodium-dependent serotonin transporter inhibitor
1	Sodium-dependent serotonin transporter inhibitors	4-Methoxyamphetamine, Amitriptyline, Amoxapine, Benzatropine, Butriptyline, Chlorpheniramine, Citalopram, Clomipramine, Cocaine, Cyclobenzaprine, Desipramine, Desvenlafaxine, Dexfenfluramine, Dexmethylphenidate, Dextromethorphan, Dopamine, Dosulepin, Doxepin, Duloxetine, Escitalopram, Etoperidone, Fenfluramine, Fluoxetine, Fluvoxamine, Imipramine, Levomilnacipran, Lumateperone, Mazindol, Mianserin, Milnacipran, Minaprine, Mirtazapine, Nefazodone, Nortriptyline, Paroxetine, Phentermine, Procaine, Protriptyline, Pseudoephedrine, Sertraline, Sibutramine, Tapentadol, Tegaserod, Tramadol, Trazodone, Trimipramine, Venlafaxine, Vilazodone, Vortioxetine
2	Sodium-dependent serotonin transporter binders	Amphetamine, Atomoxetine, Loxapine, Sertraline
3	Sodium-dependent serotonin transporter negative modulators	Ephedra sinica root, Metamfetamine, Midomafetamine, MMDA
4	Sodium-dependent serotonin transporter substrates	Fenfluramine, Mirtazapine, Tegaserod
5	Sodium-dependent serotonin transporter bindings	Meperidine
6	Sodium-dependent serotonin transporter antagonists	Butriptyline, Lorpiprazole, Zotepine
7	Sodium-dependent serotonin transporter modulators	Aripiprazole