Showing BioInteractions for Methantheline (DB00940)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 2
Enzyme Mediated Interactions 1

	Interacting Group	Interacting Drugs
	Methantheline is a Muscarinic acetylcholine receptor M1 antagonist
1	Muscarinic acetylcholine receptor M1 agonists	Carbamoylcholine, Cevimeline, Methacholine, Metoclopramide, Minaprine, Pilocarpine, Pyrantel, Succinylcholine
2	Muscarinic acetylcholine receptor M1 antagonists	Aclidinium, Amoxapine, Anisotropine methylbromide, Atropine, Benzatropine, Benzquinamide, Biperiden, Brompheniramine, Buclizine, Chlorpromazine, Chlorprothixene, Clidinium, Clozapine, Cocaine, Cyclopentolate, Cycrimine, Cyproheptadine, Darifenacin, Desipramine, Dicyclomine, Diphenidol, Disopyramide, Dosulepin, Doxepin, Fesoterodine, Flavoxate, Flupentixol, Glycopyrronium, Hexocyclium, Homatropine, Homatropine methylbromide, Hyoscyamine, Imidafenacin, Imipramine, Ipratropium, Maprotiline, Mepenzolate, Methotrimeprazine, Methscopolamine bromide, Nicardipine, Olanzapine, Oxybutynin, Oxyphencyclimine, Oxyphenonium, Pirenzepine, Pizotifen, Procyclidine, Profenamine, Promazine, Promethazine, Propantheline, Propiverine, Pyrantel, Quetiapine, Rociverine, Scopolamine, Solifenacin, Thonzylamine, Tiotropium, Tolterodine, Tramadol, Tridihexethyl, Triflupromazine, Trihexyphenidyl, Trimebutine, Tropicamide, Trospium, Umeclidinium, Ziprasidone
3	Muscarinic acetylcholine receptor M1 weak inhibitors	Buclizine
4	Muscarinic acetylcholine receptor M1 inhibitors	Escitalopram
5	Muscarinic acetylcholine receptor M1 binders	Loxapine, Terfenadine
6	Muscarinic acetylcholine receptor M1 ligands	Aripiprazole

	Interacting Group	Interacting Drugs
	Methantheline is a Histamine H2 receptor antagonist
1	Histamine H2 receptor agonists	Betazole, Histamine, Tolazoline
2	Histamine H2 receptor antagonists	Asenapine, Cimetidine, Doxepin, Epinastine, Famotidine, Metiamide, Nizatidine, Olopatadine, Promethazine, Ranitidine, Roxatidine acetate
3	Histamine H2 receptor binders	Loxapine
4	Histamine H2 receptor blockers	Amitriptyline
5	Histamine H2 receptor inhibitors	Azelastine
6	Histamine H2 receptor ligands	Aripiprazole

	Interacting Group	Interacting Drugs
	Methantheline is a Acetylcholinesterase inhibitor
1	Acetylcholinesterase inhibitors	Ambenonium, Decamethonium, Demecarium, Dipivefrin, Donepezil, Edrophonium, Ephedrine, Galantamine, Gallamine triethiodide, Huperzine A, Isoflurophate, Itopride, Mefloquine, Minaprine, Neostigmine, Physostigmine, Pyridostigmine, Ranitidine, Rivastigmine, Tacrine, Tubocurarine, Tyrothricin
2	Acetylcholinesterase antagonists	Dimetacrine, Pyridostigmine
3	Acetylcholinesterase activators	Pralidoxime
4	Acetylcholinesterase substrates	Carbamoylcholine