Showing BioInteractions for Acetylsalicylic acid (DB00945)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Prostaglandin G/H synthase 1 inhibitor
1Prostaglandin G/H synthase 1 inhibitorsAceclofenac, Acetaminophen, Antipyrine, Antrafenine, Balsalazide, Bromfenac, Bufexamac, Carprofen, Choline magnesium trisalicylate, Dexibuprofen, Dexketoprofen, Diclofenac, Diethylcarbamazine, Diflunisal, Dihomo-gamma-linolenic acid, Droxicam, Etodolac, Fenoprofen, Flurbiprofen, Hyperforin, Ibuprofen, Icosapent, Indometacin, Ketoprofen, Ketorolac, Lornoxicam, Lumiracoxib, Magnesium salicylate, Meclofenamic acid, Mefenamic acid, Meloxicam, Mesalazine, Nabumetone, Naproxen, Nepafenac, Nitroaspirin, Oxaprozin, Phenylbutazone, Piroxicam, Resveratrol, Salicylic acid, Salsalate, Sulfasalazine, Sulindac, Suprofen, Talniflumate, Tenoxicam, Tiaprofenic acid, Tolmetin, Trolamine salicylate
2Prostaglandin G/H synthase 1 inducersDesmopressin, Minoxidil
3Prostaglandin G/H synthase 1 substratesCandesartan, Candesartan cilexetil, Carvedilol, Chlorpropamide, Dapsone, Diazepam, Diclofenac, Diphenhydramine, Dronabinol, Eletriptan, Eszopiclone, Etoposide, Hexobarbital, Hydromorphone, Ifosfamide, Imatinib, Irbesartan, Ketamine, Ketobemidone, Loxoprofen, Montelukast, Nateglinide, Nortriptyline, Pioglitazone, Rofecoxib, Rosiglitazone, Seratrodast, Sulfamethoxazole, Terbinafine, Thalidomide, Torasemide, Trabectedin, Valproic Acid, Voriconazole, Zafirlukast, Zaltoprofen, Zileuton, Zolpidem, Zopiclone
4Prostaglandin G/H synthase 1 antagonistsAcemetacin, Dexketoprofen, Glycol salicylate, Loxoprofen, Menthyl salicylate, Phenyl salicylate, Propacetamol, Talniflumate, Tolfenamic Acid, Triflusal
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Prostaglandin G/H synthase 2 inhibitor
1Prostaglandin G/H synthase 2 inhibitorsAceclofenac, Acetaminophen, Adapalene, Aminosalicylic Acid, Antipyrine, Antrafenine, Balsalazide, Bromfenac, Bufexamac, Capsaicin, Carprofen, Celecoxib, Chlorphenesin, Choline magnesium trisalicylate, Cimicoxib, Cisplatin, Clodronic acid, Dexibuprofen, Dexketoprofen, Diclofenac, Diflunisal, Drospirenone, Droxicam, Etodolac, Etoricoxib, Fenoprofen, Fish oil, Flurbiprofen, Ginseng, Ibuprofen, Icosapent, Indometacin, Ketoprofen, Ketorolac, Lornoxicam, Lumiracoxib, Magnesium salicylate, Meclofenamic acid, Mefenamic acid, Meloxicam, Mesalazine, Morniflumate, Nabumetone, Naproxen, Nepafenac, Niflumic Acid, Nimesulide, Oxaprozin, Parecoxib, Phenylbutazone, Piroxicam, Pomalidomide, Resveratrol, Rofecoxib, Salicylic acid, Salsalate, Seliciclib, Sulfasalazine, Sulindac, Suprofen, Talniflumate, Tenoxicam, Tiaprofenic acid, Tolmetin, Triamcinolone, Trolamine salicylate, Valdecoxib
2Prostaglandin G/H synthase 2 negative modulatorsLenalidomide
3Prostaglandin G/H synthase 2 antagonistsAcemetacin, Alclofenac, Dexketoprofen, Glycol salicylate, Loxoprofen, Menthyl salicylate, Phenyl salicylate, Propacetamol, Talniflumate, Thalidomide, Tolfenamic Acid
4Prostaglandin G/H synthase 2 substratesDapsone, Etoposide, Loxoprofen, Omega-3 fatty acids, Omega-6 fatty acids, Thalidomide
5Prostaglandin G/H synthase 2 inducersAldesleukin, Bumetanide, Desmopressin, Nonoxynol-9, Prasterone sulfate, Risedronate, Sapropterin, Semaxanib, substance P, Tafluprost
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Aldo-keto reductase family 1 member C1 inhibitor
1Aldo-keto reductase family 1 member C1 inhibitorsSalicylic acid
2Aldo-keto reductase family 1 member C1 antagonistsNaringenin
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a 5'-AMP-activated protein kinase activator
15'-AMP-activated protein kinase inhibitorsFostamatinib
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Endothelin-1 receptor inhibitor
1Endothelin-1 receptor antagonistsAmbrisentan, Bosentan, Macitentan, Sitaxentan
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Inhibitor of nuclear factor kappa-B kinase subunit beta inhibitor
1Inhibitor of nuclear factor kappa-B kinase subunit beta inhibitorsAcetylcysteine, Auranofin, Fostamatinib, Mesalazine, Sulfasalazine
2Inhibitor of nuclear factor kappa-B kinase subunit beta inducersArsenic trioxide
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a 78 kDa glucose-regulated protein binding
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Ribosomal protein S6 kinase alpha-3 inhibitor
1Ribosomal protein S6 kinase alpha-3 inhibitorsFostamatinib
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a NF-kappa-B inhibitor alpha inhibitor
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Nuclear factor NF-kappa-B antagonist
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Cytochrome P450 2C19 inducer
1Cytochrome P450 2C19 substrates(R)-warfarin, Acenocoumarol, Adinazolam, Albendazole, Almotriptan, Ambrisentan, Aminophenazone, Amiodarone, Amitriptyline, Amoxicillin, Antipyrine, Apixaban, Aprepitant, Arformoterol, Artemether, Asunaprevir, Atomoxetine, Axitinib, Azelastine, Barbital, Benzatropine, Binimetinib, Bioallethrin, Bortezomib, Brivaracetam, Bromazepam, Brompheniramine, Bupivacaine, Cannabidiol, Carbinoxamine, Carisoprodol, Chloramphenicol, Chlorpropamide, Cilostazol, Cisapride, Citalopram, Clarithromycin, Clobazam, Clomethiazole, Clomipramine, Clopidogrel, Clotiazepam, Clozapine, Cyclophosphamide, Dapsone, Desipramine, Dexlansoprazole, Dexrabeprazole, Dextromethorphan, Diazepam, Diclofenac, Diltiazem, Diphenhydramine, Dopamine, Doxazosin, Doxepin, Dronabinol, Eletriptan, Enasidenib, Encorafenib, Enfuvirtide, Escitalopram, Esomeprazole, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Etizolam, Etravirine, Famotidine, Flunitrazepam, Fluoxetine, Flutamide, Formoterol, Fosphenytoin, Gliclazide, Glucosamine, Glyburide, Guanfacine, Haloperidol, Hexobarbital, Ibuprofen, Ifosfamide, Imatinib, Imipramine, Indometacin, Ixazomib, Ketobemidone, Labetalol, Lacosamide, Lansoprazole, Lapatinib, Levomilnacipran, Lofexidine, Lorcaserin, Lorlatinib, Lumiracoxib, Lynestrenol, Macitentan, Medical Cannabis, Melatonin, Meperidine, Mephenytoin, Meprobamate, Methadone, Methohexital, Methsuximide, Methylphenobarbital, Metoprolol, Moclobemide, Nabiximols, Nelfinavir, Nicotine, Nilutamide, Nortriptyline, Omeprazole, Ospemifene, Oxiconazole, Pantoprazole, Pentamidine, Pentobarbital, Perphenazine, Phenacetin, Phenobarbital, Phenytoin, Piperaquine, Pipotiazine, Prasugrel, Praziquantel, Primidone, Progesterone, Proguanil, Promazine, Propofol, Propranolol, Quazepam, Quetiapine, Quinine, Rabeprazole, Ramelteon, Ranitidine, Rilpivirine, Romidepsin, Rosuvastatin, Rupatadine, Selegiline, Seratrodast, Sertraline, Sildenafil, Simvastatin, St. John's Wort, Stiripentol, Tamoxifen, Tapentadol, Temazepam, Teniposide, Terbinafine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thalidomide, Thiopental, Thioridazine, Ticlopidine, Timolol, Tipranavir, Tofacitinib, Tolbutamide, Tolterodine, Trabectedin, Trimethadione, Trimipramine, Troglitazone, Valproic Acid, Venlafaxine, Verapamil, Voriconazole, Vortioxetine, Warfarin, Zolpidem, Zonisamide
2Cytochrome P450 2C19 inhibitorsAbiraterone, Aminophenazone, Amiodarone, Amitriptyline, Amprenavir, Antipyrine, Aprepitant, Armodafinil, Artenimol, Atorvastatin, Azelastine, Benzbromarone, Bicalutamide, Bortezomib, Buprenorphine, Carbamazepine, Chloramphenicol, Ciclosporin, Cimetidine, Citalopram, Clevidipine, Clinafloxacin, Clozapine, Delavirdine, Desloratadine, Dexlansoprazole, Diazepam, Dimethyl sulfoxide, Dosulepin, Dovitinib, Efavirenz, Enasidenib, Eslicarbazepine, Eslicarbazepine acetate, Esomeprazole, Ethanol, Etoricoxib, Etravirine, Felbamate, Fluconazole, Fluoxetine, Fluvastatin, Fluvoxamine, Gefitinib, Gemfibrozil, Gliclazide, Idelalisib, Imipramine, Indometacin, Isavuconazole, Isoniazid, Ketoconazole, Lansoprazole, Lenvatinib, Lobeglitazone, Lopinavir, Loratadine, Losartan, Luliconazole, Manidipine, Memantine, Mephenytoin, Methazolamide, Methimazole, Methsuximide, Miconazole, Midostaurin, Moclobemide, Modafinil, Naloxegol, Nelfinavir, Nicardipine, Nilutamide, Nilvadipine, Olanzapine, Omeprazole, Oritavancin, Oxcarbazepine, Pantoprazole, Phenelzine, Piperaquine, Probenecid, Progesterone, Quinine, Rabeprazole, Rifamycin, Ritonavir, Rucaparib, Safinamide, Sertraline, Sildenafil, Sitaxentan, Sorafenib, Stiripentol, Sulfanilamide, Telmisartan, Thalidomide, Ticlopidine, Tioconazole, Tipranavir, Topiramate, Topiroxostat, Tranylcypromine, Troglitazone, Valproic Acid, Vismodegib, Voriconazole, Warfarin, Zafirlukast, Zonisamide, Zucapsaicin
3Cytochrome P450 2C19 inducersAminoglutethimide, Apalutamide, Artemether, Barbital, Carbamazepine, Dexamethasone, Enzalutamide, Hydroxyprogesterone caproate, Letermovir, Loratadine, Lumacaftor, Midostaurin, Norethisterone, Opicapone, Phenobarbital, Prednisone, Primidone, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Rifaximin, Ritonavir, Secobarbital, St. John's Wort
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Cytochrome P450 2C8 substrate
1Cytochrome P450 2C8 substrates(R)-warfarin, (S)-Warfarin, Acetaminophen, Almotriptan, Aminophenazone, Amiodarone, Amitriptyline, Amodiaquine, Amprenavir, Antipyrine, Apalutamide, Apixaban, Atorvastatin, Azelastine, Balaglitazone, Benzyl alcohol, Beraprost, Bioallethrin, Brigatinib, Brompheniramine, Buprenorphine, Bupropion, Cabazitaxel, Caffeine, Carbamazepine, Carbinoxamine, Cerivastatin, Chloroquine, Ciglitazone, Cisapride, Clozapine, Cyclophosphamide, Dabrafenib, Dapsone, Dasabuvir, Dextromethorphan, Diazepam, Diclofenac, Diethylstilbestrol, Diltiazem, Domperidone, Elagolix, Eltrombopag, Enasidenib, Enzalutamide, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Eszopiclone, Ethinylestradiol, Fluorouracil, Fluvastatin, Halofantrine, Ibuprofen, Ifosfamide, Imatinib, Irbesartan, Ixazomib, Ketamine, Ketobemidone, Lansoprazole, Lapatinib, Levomilnacipran, Licofelone, Lidocaine, Lobeglitazone, Loperamide, Loratadine, Lorlatinib, Losartan, Mefenamic acid, Meloxicam, Mephenytoin, Mestranol, Methadone, Mirtazapine, Morphine, Muraglitazar, Mycophenolate mofetil, Naloxone, Naproxen, Netoglitazone, Nicardipine, Nicotine, Odanacatib, Olodaterol, Ombitasvir, Omeprazole, Paclitaxel, Paramethadione, Pazopanib, Pentamidine, Perospirone, Perphenazine, Phenprocoumon, Phenytoin, Pioglitazone, Piroxicam, Pitavastatin, Ponatinib, Progesterone, Propofol, Quinine, Repaglinide, Rifampicin, Riociguat, Rivoglitazone, Rosiglitazone, Selegiline, Selexipag, Seratrodast, Simvastatin, Sitagliptin, Sorafenib, Sulfadiazine, Tazarotene, Tegafur, Temazepam, Terbinafine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Theophylline, Tolbutamide, Torasemide, Tretinoin, Trimethadione, Troglitazone, Velpatasvir, Verapamil, Vortioxetine, Voxilaprevir, Warfarin, Zafirlukast, Zidovudine, Zopiclone
2Cytochrome P450 2C8 inducersAvatrombopag, Carbamazepine, Colchicine, Cyclophosphamide, Dexamethasone, Gemfibrozil, Hydrocortisone, Hydrocortisone aceponate, Hydrocortisone acetate, Hydrocortisone butyrate, Hydrocortisone cypionate, Hydrocortisone phosphate, Hydrocortisone probutate, Hydrocortisone succinate, Hydrocortisone valerate, Ifosfamide, Isavuconazole, Ivosidenib, Lumacaftor, Midostaurin, Nilotinib, Phenobarbital, Phenytoin, Primidone, Probenecid, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Rifaximin, Ritonavir, Secobarbital
3Cytochrome P450 2C8 inhibitorsAbiraterone, Amitriptyline, Amlodipine, Amodiaquine, Atazanavir, Atorvastatin, Belinostat, Bexarotene, Bezafibrate, Bosutinib, Cabozantinib, Candesartan, Candesartan cilexetil, Celecoxib, Cerivastatin, Chloramphenicol, Cholecalciferol, Ciclosporin, Cimetidine, Clopidogrel, Clotrimazole, Cocaine, Colchicine, Crisaborole, Dabrafenib, Deferasirox, Delavirdine, Dextropropoxyphene, Diethylstilbestrol, Efavirenz, Eltrombopag, Enasidenib, Enzalutamide, Erlotinib, Ethinylestradiol, Etoposide, Felodipine, Fenofibrate, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fluvoxamine, Gemfibrozil, Genistein, Idelalisib, Irbesartan, Isavuconazole, Isoniazid, Ketoconazole, Ketoprofen, Lapatinib, Lenvatinib, Letermovir, Levothyroxine, Licofelone, Liotrix, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Medroxyprogesterone acetate, Mefenamic acid, Meloxicam, Metronidazole, Midostaurin, Mifepristone, Mometasone, Montelukast, Nabilone, Nicardipine, Nifedipine, Nilotinib, Nilutamide, Nilvadipine, Opicapone, Oxybutynin, Paroxetine, Pazopanib, Phenelzine, Pioglitazone, Piroxicam, Ponatinib, Pravastatin, Propafenone, Pyrimethamine, Quercetin, Quinidine, Quinine, Rabeprazole, Raloxifene, Regorafenib, Rifamycin, Ritonavir, Rofecoxib, Rosiglitazone, Rucaparib, Rutin, Salmeterol, Saquinavir, Simvastatin, Sorafenib, Spironolactone, Sulfamethoxazole, Sulfaphenazole, Sulfinpyrazone, Tamoxifen, Tegaserod, Terfenadine, Teriflunomide, Thioridazine, Ticlopidine, Tioconazole, Topiroxostat, Trametinib, Triazolam, Trimethoprim, Troglitazone, Troleandomycin, Valproic Acid, Vemurafenib, Vismodegib, Warfarin, Zafirlukast
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Cytochrome P450 2C9 substrate
1Cytochrome P450 2C9 inhibitorsAbiraterone, Acetyl sulfisoxazole, Agomelatine, Amiodarone, Amlodipine, Amodiaquine, Anastrozole, Armodafinil, Atorvastatin, Atovaquone, Avasimibe, Azelastine, Belinostat, Benzbromarone, Bicalutamide, Bortezomib, Candesartan, Capecitabine, Ceritinib, Cerivastatin, Ciclosporin, Cimetidine, Cimicifuga racemosa, Cisplatin, Clevidipine, Clinafloxacin, Clopidogrel, Clotrimazole, Crisaborole, Curcumin, Cyclizine, Delavirdine, Diacerein, Diethylstilbestrol, Doconexent, Dosulepin, Efavirenz, Enasidenib, Epinephrine, Estrone sulfate, Ethanol, Etoricoxib, Etravirine, Felbamate, Felodipine, Fenofibrate, Flecainide, Floxuridine, Fluconazole, Fluorouracil, Fluoxetine, Fluvastatin, Fluvoxamine, Gefitinib, Gemfibrozil, Genistein, Ginkgo biloba, Glyburide, Imatinib, Iproniazid, Isavuconazole, Isoniazid, Ketoconazole, Ketoprofen, Lansoprazole, Leflunomide, Lenvatinib, Lifitegrast, Lobeglitazone, Lopinavir, Lovastatin, Lumacaftor, Manidipine, Medical Cannabis, Medroxyprogesterone acetate, Methimazole, Metronidazole, Miconazole, Midostaurin, Mifepristone, Modafinil, Nabilone, Nelfinavir, Nilotinib, Noscapine, Oritavancin, Oxandrolone, Parecoxib, Paroxetine, Phenylbutazone, Phenytoin, Piperine, Pranlukast, Promethazine, Quinidine, Rabeprazole, Regorafenib, Rhein, Rifamycin, Rucaparib, Safinamide, Seproxetine, Sertraline, Sildenafil, Simvastatin, Sitaxentan, Sorafenib, Stiripentol, Sulconazole, Sulfadiazine, Sulfadimethoxine, Sulfamethizole, Sulfamethoxazole, Sulfamoxole, Sulfaphenazole, Sulfapyridine, Sulfinpyrazone, Sulfisoxazole, Suprofen, Tamoxifen, Teniposide, Ticagrelor, Ticlopidine, Tolcapone, Topiroxostat, Torasemide, Tranylcypromine, Troglitazone, Valdecoxib, Valproic Acid, Valsartan, Vemurafenib, Verapamil, Vismodegib, Voriconazole, Zafirlukast, Zucapsaicin
2Cytochrome P450 2C9 substrates(R)-warfarin, (S)-Warfarin, Aceclofenac, Acenocoumarol, Acetaminophen, Acetohexamide, Alosetron, Alprazolam, Aminophenazone, Amitriptyline, Amprenavir, Antipyrine, Apixaban, Arachidonic Acid, Arformoterol, Artemether, Asunaprevir, Atazanavir, Azelastine, Bexarotene, Bioallethrin, Bortezomib, Bosentan, Brivaracetam, Buprenorphine, Bupropion, Cabozantinib, Caffeine, Candesartan, Candesartan cilexetil, Cannabidiol, Carbutamide, Carvedilol, Celecoxib, Chlorpropamide, Cinnarizine, Cisapride, Clopidogrel, Clozapine, Coumarin, Cyclophosphamide, Dacomitinib, Dapagliflozin, Dapsone, Dextromethorphan, Diazepam, Diclofenac, Dicoumarol, Diphenhydramine, Doconexent, Dolasetron, Donepezil, Dorzolamide, Doxepin, Dronabinol, Eletriptan, Enasidenib, Enzalutamide, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Estrone sulfate, Eszopiclone, Etodolac, Etoricoxib, Etravirine, Fluindione, Flunarizine, Flunitrazepam, Fluoxetine, Flurbiprofen, Fluvastatin, Formoterol, Fosphenytoin, Glibornuride, Gliclazide, Glimepiride, Glipizide, Gliquidone, Glisoxepide, Glyburide, Haloperidol, Halothane, Hexobarbital, Histamine, Hydromorphone, Ibuprofen, Idarubicin, Ifosfamide, Imatinib, Indisulam, Indometacin, Irbesartan, Ixazomib, Ketamine, Ketobemidone, Ketoprofen, Lacosamide, Leflunomide, Lesinurad, Licofelone, Lidocaine, Lornoxicam, Losartan, Lumiracoxib, Lynestrenol, Medical Cannabis, Mefenamic acid, Melatonin, Meloxicam, Mephenytoin, Mestranol, Metahexamide, Methadone, Methoxyflurane, Mirtazapine, Moclobemide, Montelukast, Nabiximols, Naproxen, Nateglinide, Netupitant, Niclosamide, Nicotine, Olodaterol, Omeprazole, Ondansetron, Ospemifene, Paramethadione, Parecoxib, Perphenazine, Phenacetin, Phenobarbital, Phenprocoumon, Phenylbutazone, Phenytoin, Pioglitazone, Piperaquine, Piroxicam, Pitavastatin, Prasugrel, Primidone, Progesterone, Proguanil, Promazine, Propacetamol, Propofol, Quazepam, Quinidine, Quinine, Ramelteon, Rofecoxib, Rosiglitazone, Rosuvastatin, Rupatadine, Salicylic acid, Selegiline, Seratrodast, Sertraline, Sildenafil, Sitaxentan, Sulfamethoxazole, Sulfinpyrazone, Suprofen, Tamoxifen, Tapentadol, Temazepam, Tenoxicam, Terbinafine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thalidomide, Thiamylal, Tolazamide, Tolbutamide, Tolterodine, Torasemide, Trabectedin, Tranilast, Treprostinil, Tretinoin, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Valdecoxib, Valproic Acid, Valsartan, Venlafaxine, Verapamil, Vicriviroc, Vismodegib, Voriconazole, Vortioxetine, Warfarin, Ximelagatran, Zafirlukast, Zaltoprofen, Zidovudine, Zileuton, Zolpidem, Zopiclone
3Cytochrome P450 2C9 inducersApalutamide, Aprepitant, Avatrombopag, Bosentan, Carbamazepine, Dabrafenib, Dapsone, Delafloxacin, Enzalutamide, Etravirine, Fosaprepitant, Fosphenytoin, Isavuconazole, Ivosidenib, Ketamine, Lansoprazole, Letermovir, Lopinavir, Lumacaftor, Midostaurin, Modafinil, Peginterferon alfa-2b, Phenobarbital, Phenytoin, Primidone, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Ritonavir, Secobarbital, Vigabatrin
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Solute carrier family 22 member 6 inhibitor
1Solute carrier family 22 member 6 inhibitorsAcetaminophen, Acetazolamide, Acyclovir, Adefovir Dipivoxil, Alprostadil, Aminohippuric acid, Aminophenazone, Amoxicillin, Antipyrine, Aspartame, Ataluren, Baricitinib, Benzylpenicillin, Bumetanide, Cabotegravir, Caprylic acid, Captopril, Carbenicillin, Carprofen, Caspofungin, Cefacetrile, Cefadroxil, Cefalotin, Cefamandole, Cefazolin, Cefoperazone, Cefotaxime, Cefotiam, Cefradine, Ceftazidime, Ceftriaxone, Cephalexin, Chloramphenicol, Chlorothiazide, Chlorpropamide, Ciclosporin, Cidofovir, Cilastatin, Cimetidine, Cinoxacin, Cloxacillin, Cyclothiazide, Dabrafenib, Diclofenac, Diflunisal, Dinoprostone, Dolutegravir, Doxycycline, Ellagic Acid, Enalapril, Enasidenib, Etacrynic acid, Ethoxzolamide, Etodolac, Flufenamic Acid, Fluorescein, Flurbiprofen, Folic Acid, Foscarnet, Furosemide, Ganciclovir, Gentamicin, Glutaric Acid, Glyburide, Hydrochlorothiazide, Ibuprofen, Indometacin, Ketoprofen, Lenvatinib, Losartan, Meclofenamic acid, Methazolamide, Methotrexate, Minocycline, Nafcillin, Nalidixic acid, Naproxen, Nateglinide, Norfloxacin, Novobiocin, Ofloxacin, Oxyphenbutazone, Oxytetracycline, Phenacetin, Phenylbutazone, Piperacillin, Piroxicam, Pravastatin, Probenecid, Ranitidine, Riboflavin, Rifampicin, Rucaparib, Salicylic acid, Silibinin A, Streptomycin, Sulindac, Taurocholic Acid, Tetracycline, Tolbutamide, Tolmetin, Topiroxostat, Trifluridine, Valproic Acid
2Solute carrier family 22 member 6 inducersFurosemide
3Solute carrier family 22 member 6 substratesAcyclovir, Adefovir Dipivoxil, Alprostadil, Aminohippuric acid, Bumetanide, Captopril, Cefacetrile, Cefaloridine, Cefazolin, Cefdinir, Cefotiam, Ceftibuten, Ceftizoxime, Cephalexin, Cidofovir, Cimetidine, Conjugated estrogens, Cyclic Adenosine Monophosphate, Didanosine, Dinoprostone, Edaravone, Ellagic Acid, Fluorescein, Glutaric Acid, Grepafloxacin, Indometacin, L-Citrulline, Lamivudine, Levofloxacin, Methotrexate, Probenecid, Ranitidine, Silibinin A, Stavudine, Taurocholic Acid, Tazobactam, Tenofovir disoproxil, Trifluridine, Zalcitabine, Zidovudine
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Multidrug resistance protein 1 substrate
1Multidrug resistance protein 1 inducersAldosterone, Amiodarone, Amprenavir, Apalutamide, Carbamazepine, Cholic Acid, Ciclosporin, Cimetidine, Clotrimazole, Daunorubicin, Dexamethasone, Digoxin, Doxorubicin, Estriol, Estrone, Etravirine, Indinavir, Levothyroxine, Liothyronine, Liotrix, Lumacaftor, Midazolam, Mifepristone, Mitoxantrone, Nefazodone, Nelfinavir, Nifedipine, Norethisterone, Oxcarbazepine, Phenobarbital, Platelet Activating Factor, Progesterone, Reserpine, Rifampicin, Ritonavir, Saquinavir, Sirolimus, Spironolactone, St. John's Wort, Streptozocin, Tacrolimus, Tamoxifen, Tesmilifene, Trazodone, Trimethoprim, Verapamil, Vinblastine, Vincristine
2Multidrug resistance protein 1 substratesAbemaciclib, Acebutolol, Acetaminophen, Afatinib, Aldosterone, Alitretinoin, Ambrisentan, Amitriptyline, Amprenavir, Apixaban, Arsenic trioxide, Asunaprevir, Atazanavir, Atenolol, Avatrombopag, Axitinib, Belinostat, Betamethasone, Betrixaban, Bosutinib, Bromocriptine, Cabazitaxel, Cabergoline, Caffeine, Camptothecin, Canagliflozin, Carfilzomib, Ceritinib, Cerivastatin, Chloroquine, Chlorpromazine, Ciclosporin, Cimetidine, Ciprofloxacin, Cisplatin, Citalopram, Clarithromycin, Clobazam, Clomifene, Clonidine, Clopidogrel, Clozapine, Cobimetinib, Colchicine, Conjugated estrogens, Copanlisib, Crizotinib, Dabigatran etexilate, Dabrafenib, Dacomitinib, Dactinomycin, Dapagliflozin, Dasabuvir, Dasatinib, Daunorubicin, Debrisoquin, Dexamethasone, Diazepam, Diethylstilbestrol, Digitoxin, Digoxin, Diltiazem, Dipyridamole, Docetaxel, Dolutegravir, Domperidone, Doxorubicin, Duvelisib, Edoxaban, Elagolix, Elbasvir, Eletriptan, Epinastine, Erlotinib, Ertugliflozin, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone, Ethinylestradiol, Etoposide, Ezetimibe, Fesoterodine, Fexofenadine, Fidaxomicin, Fluciclovine (18F), Fluticasone, Fluticasone furoate, Fluticasone propionate, Gefitinib, Gemcitabine, Gilteritinib, Glecaprevir, Grapiprant, Grazoprevir, Grepafloxacin, Haloperidol, Hydrocortisone, Ibuprofen, Idelalisib, Imatinib, Imipramine, Indacaterol, Indinavir, Indometacin, Inotuzumab ozogamicin, Irinotecan, Ivermectin, Ivosidenib, Ketazolam, Ketoconazole, Lamivudine, Lamotrigine, Lansoprazole, Ledipasvir, Lenalidomide, Lenvatinib, Letermovir, Levetiracetam, Levofloxacin, Levomilnacipran, Linagliptin, Loperamide, Losartan, Lusutrombopag, Mannitol, Methotrexate, Methylprednisolone, Metoprolol, Midazolam, Mirabegron, Mitoxantrone, Morphine, Moxidectin, Mycophenolate mofetil, Nadolol, Naloxone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nintedanib, Nizatidine, Odanacatib, Olanzapine, Omadacycline, Ombitasvir, Osimertinib, Paclitaxel, Paliperidone, Panobinostat, Paritaprevir, Pazopanib, Phenobarbital, Phenytoin, Pibrentasvir, Pitavastatin, Pomalidomide, Ponatinib, Pravastatin, Prazosin, Prednisolone, Prednisone, Progesterone, Propranolol, Prucalopride, Quetiapine, Quinidine, Quinine, Ranitidine, Regorafenib, Reserpine, Revefenacin, Rifampicin, Rifamycin, Risperidone, Ritonavir, Rivaroxaban, Romidepsin, Rucaparib, Saquinavir, Selexipag, Sildenafil, Silodosin, Simeprevir, Sitagliptin, Sofosbuvir, Somatostatin, Sorafenib, Sparfloxacin, Sphingosine, Stanolone, Stanolone acetate, Sumatriptan, Tacrine, Tacrolimus, Talazoparib, Tamoxifen, Taurocholic Acid, Technetium Tc-99m sestamibi, Telaprevir, Temsirolimus, Tenofovir, Tenofovir alafenamide, Tenofovir disoproxil, Testosterone propionate, Ticagrelor, Timolol, Tolvaptan, Topotecan, Toremifene, Trastuzumab emtansine, Trimipramine, Ubidecarenone, Umeclidinium, Vardenafil, Vecuronium, Velpatasvir, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinflunine, Vinorelbine, Vismodegib, Voxilaprevir, Zidovudine
3Multidrug resistance protein 1 inhibitorsAbemaciclib, Acetaminophen, Afatinib, Albendazole, Alectinib, Alfentanil, Amiodarone, Amitriptyline, Amlodipine, Amodiaquine, Amsacrine, Astemizole, Atazanavir, Atorvastatin, Azelastine, Azithromycin, Benzocaine, Bepridil, Boceprevir, Bosutinib, Bromocriptine, Buprenorphine, Buspirone, Cabazitaxel, Caffeine, Canagliflozin, Candesartan, Candesartan cilexetil, Captopril, Carvedilol, Caspofungin, Chloroquine, Chlorpromazine, Chlorprothixene, Cholesterol, Ciclosporin, Cilazapril, Citalopram, Clarithromycin, Clofazimine, Clomipramine, Clotrimazole, Cobicistat, Colchicine, Colforsin, Concanamycin A, Crizotinib, Curcumin, Daclatasvir, Dacomitinib, Dactinomycin, Darunavir, Dasatinib, Daunorubicin, Desipramine, Desloratadine, Desmethylsertraline, Dexamethasone, Dexniguldipine, Dexverapamil, Diclofenac, Digoxin, Dihydroergotamine, Diltiazem, Dipyridamole, Dofequidar, Dovitinib, Doxazosin, Doxepin, Doxorubicin, Dronabinol, Dronedarone, Emopamil, Enalapril, Enasidenib, Enzalutamide, Ergometrine, Ergotamine, Erythromycin, Estramustine, Etoposide, Felodipine, Fentanyl, Fexofenadine, Fidaxomicin, Fluconazole, Fluoxetine, Flupentixol, Fluphenazine, Flurazepam, Fluvoxamine, Gefitinib, Genistein, Glecaprevir, Glyburide, Gramicidin D, Grepafloxacin, Haloperidol, HM-30181, Hycanthone, Hydroxychloroquine, Idelalisib, Imatinib, Indinavir, Indometacin, Isavuconazole, Isavuconazonium, Itraconazole, Ivacaftor, Ivermectin, Ivosidenib, Ketoconazole, Lansoprazole, Lapatinib, Letermovir, Levofloxacin, Lidocaine, Lomerizine, Lomitapide, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Lusutrombopag, Mefloquine, Megestrol acetate, Methadone, Mibefradil, Miconazole, Midazolam, Mifepristone, Mirabegron, Mitoxantrone, Nefazodone, Nelfinavir, Neratinib, Nicardipine, Nifedipine, Nilotinib, Nisoldipine, Nitrendipine, Omeprazole, ONT-093, Paclitaxel, Paliperidone, Pantoprazole, Paroxetine, Pibrentasvir, Pimozide, Ponatinib, Posaconazole, Prazosin, Primaquine, Progesterone, Promethazine, Propafenone, Protriptyline, Quercetin, Quinacrine, Quinidine, Quinine, Ranitidine, Reboxetine, Regorafenib, Reserpine, Reversin 121, Rifamycin, Rilpivirine, Ritonavir, Rolapitant, Rucaparib, Saquinavir, Sarecycline, Scopolamine, Selegiline, Sertraline, Sildenafil, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Staurosporine, Sunitinib, Tacrolimus, Tamoxifen, Taurocholic Acid, Telaprevir, Telmisartan, Temsirolimus, Tenofovir, Tenofovir disoproxil, Terazosin, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetrandrine, Ticagrelor, Tolvaptan, Trifluoperazine, Triflupromazine, Trimethoprim, Troleandomycin, Vardenafil, Velpatasvir, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Voacamine, Voxilaprevir, Zimelidine
4Multidrug resistance protein 1 transportersalpha-Tocopherol acetate, Ledipasvir, Tocopherol
5Multidrug resistance protein 1 bindersTechnetium Tc-99m tetrofosmin
6Multidrug resistance protein 1 antagonistsTocofersolan
Interacting GroupInteracting Drugs
Acetylsalicylic acid is a Solute carrier family 22 member 7 substrate
1Solute carrier family 22 member 7 inducersTestosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate
2Solute carrier family 22 member 7 inhibitorsBumetanide, Cefalotin, Cefamandole, Cefoperazone, Cefotaxime, Cholic Acid, Cimetidine, Clarithromycin, Dinoprostone, Enalapril, Ganciclovir, Glyburide, Ketoprofen, Minocycline, Oxtriphylline, Oxytetracycline, Pravastatin, Probenecid, Rifampicin, Tetracycline, Theophylline
3Solute carrier family 22 member 7 substratesAllopurinol, Aminohippuric acid, Cimetidine, Cyclic Adenosine Monophosphate, Dinoprostone, Docetaxel, Fluorouracil, Glutaric Acid, Indometacin, Methotrexate, Salicylic acid, Tegafur-uracil, Valproic Acid, Zalcitabine