Showing BioInteractions for Iloprost (DB01088)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting Group | Interacting Drugs | |
---|---|---|
Iloprost is a Prostacyclin receptor agonist | ||
1 | Prostacyclin receptor antagonists | Dinoprost tromethamine |
2 | Prostacyclin receptor agonists | Epoprostenol, Selexipag, Treprostinil |
Interacting Group | Interacting Drugs | |
---|---|---|
Iloprost is a cAMP-specific 3',5'-cyclic phosphodiesterase 4A inducer | ||
1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitors | Crisaborole, Dipyridamole, Drotaverine, Dyphylline, Enprofylline, Ibudilast, Oxtriphylline, Roflumilast, Theophylline, Tofisopam |
Interacting Group | Interacting Drugs | |
---|---|---|
Iloprost is a cAMP-specific 3',5'-cyclic phosphodiesterase 4B inducer | ||
1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitors | (R)-Rolipram, (S)-Rolipram, Caffeine, Cilomilast, Crisaborole, Dyphylline, Enprofylline, Filaminast, Ibudilast, Papaverine, Roflumilast, Theobromine, Theophylline |
Interacting Group | Interacting Drugs | |
---|---|---|
Iloprost is a cAMP-specific 3',5'-cyclic phosphodiesterase 4C inducer | ||
1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4C inhibitors | Crisaborole, Dyphylline, Ibudilast, Roflumilast |
Interacting Group | Interacting Drugs | |
---|---|---|
Iloprost is a cAMP-specific 3',5'-cyclic phosphodiesterase 4D inducer | ||
1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitors | Cilomilast, Crisaborole, Dyphylline, Ibudilast, Roflumilast |
Interacting Group | Interacting Drugs | |
---|---|---|
Iloprost is a Prostaglandin E2 receptor EP1 subtype agonist | ||
1 | Prostaglandin E2 receptor EP1 subtype agonists | Alprostadil, Bimatoprost, Carboprost tromethamine, Dinoprostone, Limaprost, Misoprostol |
Interacting Group | Interacting Drugs | |
---|---|---|
Iloprost is a Prostaglandin D2 receptor 2 agonist | ||
1 | Prostaglandin D2 receptor 2 antagonists | Sulindac |
2 | Prostaglandin D2 receptor 2 agonists | Alprostadil, Dinoprost, Dinoprostone |
Interacting Group | Interacting Drugs | |
---|---|---|
Iloprost is a Solute carrier organic anion transporter family member 2A1 substrate | ||
1 | Solute carrier organic anion transporter family member 2A1 inducers | Phenobarbital |
2 | Solute carrier organic anion transporter family member 2A1 inhibitors | beta-D-fructofuranose 1,6-bisphosphate, D-glyceraldehyde 3-phosphate, Furosemide, Glucose-6-Phosphate, Lactic acid, Phosphoenolpyruvate, Pyruvic acid, Rifamycin |
3 | Solute carrier organic anion transporter family member 2A1 substrates | Alprostadil, Arachidonic Acid, Dinoprostone, Latanoprost |
Interacting Group | Interacting Drugs | |
---|---|---|
Iloprost is a Solute carrier organic anion transporter family member 3A1 substrate | ||
1 | Solute carrier organic anion transporter family member 3A1 inhibitors | Alprostadil, Aminohippuric acid, Lobeglitazone, Taurocholic acid |
2 | Solute carrier organic anion transporter family member 3A1 substrates | Benzylpenicillin, Conjugated estrogens, Dinoprostone, Methotrexate, Safinamide, Thyroid, porcine |