Showing BioInteractions for DB01144 (Diclofenamide)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Diclofenamide is a Carbonic anhydrase 1 inhibitor
1Carbonic anhydrase 1 inhibitorsAcetazolamide, Amlodipine, Bendroflumethiazide, Benzthiazide, Brinzolamide, Chlorothiazide, Cyclothiazide, Diazoxide, Dorzolamide, Ellagic Acid, Ethinamate, Ethoxzolamide, Hydrochlorothiazide, Hydroflumethiazide, Methazolamide, Methocarbamol, Methyclothiazide, Quinethazone, Sodium carbonate, Sodium sulfate, Topiramate, Trichlormethiazide, Zonisamide
2Carbonic anhydrase 1 substratesZinc
Interacting GroupInteracting Drugs
Diclofenamide is a Carbonic anhydrase 4 inhibitor
1Carbonic anhydrase 4 inhibitorsAcetazolamide, Bendroflumethiazide, Benzthiazide, Brinzolamide, Chlorothiazide, Cyclothiazide, Dorzolamide, Ellagic Acid, Ethoxzolamide, Hydrochlorothiazide, Hydroflumethiazide, Methazolamide, Methyclothiazide, Sodium carbonate, Topiramate, Trichlormethiazide, Zonisamide
Interacting GroupInteracting Drugs
Diclofenamide is a Carbonic anhydrase 2 inhibitor
1Carbonic anhydrase 2 inhibitorsAcetazolamide, Bendroflumethiazide, Benzthiazide, Brinzolamide, Celecoxib, Chlorothiazide, Cyclothiazide, Diazoxide, Dorzolamide, Ellagic Acid, Ethinamate, Ethoxzolamide, Hydrochlorothiazide, Hydroflumethiazide, Methazolamide, Methyclothiazide, Quinethazone, Sodium carbonate, Sodium sulfate, Sulpiride, Topiramate, Trichlormethiazide, Valdecoxib, Zonisamide
Interacting GroupInteracting Drugs
Diclofenamide is a Carbonic anhydrase 7 inhibitor
1Carbonic anhydrase 7 inhibitorsAcetazolamide, Ellagic Acid, Ethoxzolamide, Methazolamide, Zonisamide
Interacting GroupInteracting Drugs
Diclofenamide is a Carbonic anhydrase 3 inhibitor
1Carbonic anhydrase 3 inhibitorsAcetazolamide, Brinzolamide, Celecoxib, Dorzolamide, Ellagic Acid, Ethoxzolamide, Methazolamide, Saccharin, Sulpiride, Topiramate, Valdecoxib, Zonisamide
Interacting GroupInteracting Drugs
Diclofenamide is a Cytochrome P450 2C9 inducer
1Cytochrome P450 2C9 inhibitorsAbiraterone, Acenocoumarol, Agomelatine, Aminophenazone, Amiodarone, Amlodipine, Amodiaquine, Anastrozole, Aprepitant, Armodafinil, Atorvastatin, Atovaquone, Avasimibe, Azelastine, Belinostat, Benzbromarone, Bicalutamide, Bortezomib, Candesartan, Candesartan cilexetil, Capecitabine, Ceritinib, Cerivastatin, Chloramphenicol, Cholecalciferol, Cimetidine, Cimicifuga racemosa, Cisplatin, Clevidipine, Clopidogrel, Clotrimazole, Clozapine, Cocaine, Colchicine, Crisaborole, Cyclizine, Cyclosporine, Delavirdine, Desloratadine, Dexfenfluramine, Dextropropoxyphene, Diacerein, Diazepam, Diclofenac, Dicoumarol, Diethylstilbestrol, Diltiazem, Disulfiram, Doconexent, Dosulepin, Efavirenz, Enasidenib, Epinephrine, Eprosartan, Ethanol, Etodolac, Etoricoxib, Etravirine, Felodipine, Fenofibrate, Flecainide, Floxuridine, Fluconazole, Fluorouracil, Fluoxetine, Fluvastatin, Fluvoxamine, Gefitinib, Gemfibrozil, Ginkgo biloba, Glyburide, Histamine, Human Serum Albumin, Ibuprofen, Imatinib, Indinavir, Irbesartan, Isavuconazole, Isoniazid, Ketoconazole, Ketoprofen, Lansoprazole, Leflunomide, Lifitegrast, Lobeglitazone, Lopinavir, Loratadine, Lornoxicam, Losartan, Lovastatin, Lumacaftor, Manidipine, Medroxyprogesterone acetate, Mefenamic acid, Meloxicam, Methazolamide, Methimazole, Metronidazole, Miconazole, Midostaurin, Moclobemide, Modafinil, Nelfinavir, Nevirapine, Nicardipine, Nifedipine, Nilotinib, Nilutamide, Nilvadipine, Noscapine, Olanzapine, Omeprazole, Pantoprazole, Parecoxib, Paroxetine, Phentermine, Phenylbutazone, Phenytoin, Pioglitazone, Piroxicam, Pranlukast, Pravastatin, Probenecid, Progesterone, Promethazine, Propafenone, Propofol, Pyrimethamine, Quinidine, Quinine, Rabeprazole, Regorafenib, Rhein, Ritonavir, Rosiglitazone, Rosuvastatin, Rucaparib, Rutin, Saquinavir, Selegiline, Seratrodast, Sertraline, Sildenafil, Simvastatin, Sitaxentan, Sorafenib, Stiripentol, Sulconazole, Sulfadiazine, Sulfadimethoxine, Sulfamethizole, Sulfamethoxazole, Sulfamoxole, Sulfanilamide, Sulfaphenazole, Sulfapyridine, Sulfinpyrazone, Sulfisoxazole, Suprofen, Tamoxifen, Tegaserod, Teniposide, Thioridazine, Ticagrelor, Ticlopidine, Tioconazole, Tolbutamide, Tolcapone, Topiroxostat, Tranylcypromine, Triazolam, Trimethoprim, Troglitazone, Valdecoxib, Valproic Acid, Valsartan, Verapamil, Vismodegib, Voriconazole, Warfarin, Zafirlukast, Zucapsaicin
2Cytochrome P450 2C9 substratesAceclofenac, Acenocoumarol, Acetaminophen, Acetylsalicylic acid, Alosetron, Alprazolam, Aminophenazone, Amiodarone, Amitriptyline, Amprenavir, Antipyrine, Apixaban, Arachidonic Acid, Arformoterol, Artemether, Asunaprevir, Atazanavir, Azelastine, Bexarotene, Bioallethrin, Bortezomib, Bosentan, Brivaracetam, Brompheniramine, Buprenorphine, Bupropion, Cabozantinib, Caffeine, Candesartan, Candesartan cilexetil, Cannabidiol, Carbinoxamine, Carvedilol, Celecoxib, Chlorpropamide, Cinnarizine, Cisapride, Clopidogrel, Clozapine, Cyclophosphamide, Dapagliflozin, Dapsone, Dextromethorphan, Diazepam, Diclofenac, Dicoumarol, Diltiazem, Diphenhydramine, Doconexent, Dolasetron, Donepezil, Dopamine, Dorzolamide, Doxepin, Dronabinol, Eletriptan, Enasidenib, Epoprostenol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Eszopiclone, Etodolac, Etoricoxib, Etravirine, Flunarizine, Flunitrazepam, Fluoxetine, Flurbiprofen, Fluvastatin, Formoterol, Fosphenytoin, Gavestinel, Gliclazide, Glimepiride, Glipizide, Glyburide, Guanfacine, Haloperidol, Halothane, Hexobarbital, Histamine, Hydromorphone, Ibuprofen, Idarubicin, Ifosfamide, Imatinib, Indisulam, Indomethacin, Irbesartan, Ixazomib, Ketamine, Ketobemidone, Ketoprofen, Lansoprazole, Leflunomide, Lesinurad, Licofelone, Lidocaine, Loratadine, Lornoxicam, Losartan, Lumiracoxib, Medical Cannabis, Mefenamic acid, Melatonin, Meloxicam, Mephenytoin, Mestranol, Methadone, Methoxyflurane, Metronidazole, Mirtazapine, Moclobemide, Montelukast, Nabiximols, Naproxen, Nateglinide, Netupitant, Nevirapine, Niclosamide, Nicotine, Nortriptyline, Olodaterol, Omeprazole, Ondansetron, Ospemifene, Oxaprozin, Paclitaxel, Paramethadione, Parecoxib, Perphenazine, Phenacetin, Phenobarbital, Phenprocoumon, Phenylbutazone, Phenytoin, Pioglitazone, Piperaquine, Piroxicam, Pitavastatin, Prasugrel, Pravastatin, Progesterone, Proguanil, Promazine, Propofol, Quazepam, Quinidine, Quinine, Rifampicin, Rofecoxib, Rosiglitazone, Rosuvastatin, Rupatadine, Salicylic acid, Selegiline, Seratrodast, Sertraline, Sildenafil, Sitaxentan, Sulfadiazine, Sulfamethoxazole, Sulfamoxole, Sulfinpyrazone, Sulfisoxazole, Suprofen, Tamoxifen, Tapentadol, Temazepam, Tenoxicam, Terbinafine, Terfenadine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thalidomide, Theophylline, Thiamylal, Tolbutamide, Tolterodine, Torasemide, Trabectedin, Treprostinil, Tretinoin, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Valdecoxib, Valproic Acid, Valsartan, Venlafaxine, Verapamil, Vicriviroc, Vismodegib, Voriconazole, Vortioxetine, Warfarin, Ximelagatran, Zafirlukast, Zalcitabine, Zaltoprofen, Zidovudine, Zileuton, Zolpidem, Zopiclone
3Cytochrome P450 2C9 inducersApalutamide, Aprepitant, Atorvastatin, Bosentan, Carbamazepine, Cerivastatin, Colchicine, Cyclophosphamide, Dapsone, Delafloxacin, Dexamethasone, Enzalutamide, Estrone sulfate, Fluvastatin, Fosphenytoin, Ifosfamide, Isavuconazole, Lansoprazole, Letermovir, Lovastatin, Lumacaftor, Midostaurin, Modafinil, Nicardipine, Nifedipine, Phenobarbital, Phentermine, Phenytoin, Primidone, Rifampicin, Rifapentine, Ritonavir, Secobarbital, Seratrodast, Simvastatin