| 7-Nitroindazole | The risk or severity of adverse effects can be increased when Desflurane is combined with 7-Nitroindazole. | Experimental |
| Acebutolol | The risk or severity of adverse effects can be increased when Acebutolol is combined with Desflurane. | Approved |
| Acepromazine | The risk or severity of adverse effects can be increased when Desflurane is combined with Acepromazine. | Approved, Vet Approved |
| Aceprometazine | The risk or severity of adverse effects can be increased when Desflurane is combined with Aceprometazine. | Approved |
| Acetazolamide | The risk or severity of adverse effects can be increased when Desflurane is combined with Acetazolamide. | Approved, Vet Approved |
| Adipiplon | The risk or severity of adverse effects can be increased when Desflurane is combined with adipiplon. | Investigational |
| Agomelatine | The risk or severity of adverse effects can be increased when Desflurane is combined with Agomelatine. | Approved, Investigational |
| Aldesleukin | The risk or severity of adverse effects can be increased when Aldesleukin is combined with Desflurane. | Approved |
| Alfaxalone | The risk or severity of adverse effects can be increased when Desflurane is combined with Alfaxalone. | Vet Approved |
| Alfentanil | The risk or severity of adverse effects can be increased when Alfentanil is combined with Desflurane. | Approved, Illicit |
| Aliskiren | The risk or severity of adverse effects can be increased when Aliskiren is combined with Desflurane. | Approved, Investigational |
| Allopregnanolone | The risk or severity of adverse effects can be increased when Desflurane is combined with Sage 547. | Investigational |
| Alphacetylmethadol | The risk or severity of adverse effects can be increased when Desflurane is combined with Alphacetylmethadol. | Experimental, Illicit |
| Alprazolam | The risk or severity of adverse effects can be increased when Alprazolam is combined with Desflurane. | Approved, Illicit, Investigational |
| Amifostine | The risk or severity of adverse effects can be increased when Amifostine is combined with Desflurane. | Approved, Investigational |
| Amiloride | The risk or severity of adverse effects can be increased when Amiloride is combined with Desflurane. | Approved |
| Amiodarone | Desflurane may increase the QTc-prolonging activities of Amiodarone. | Approved, Investigational |
| Amisulpride | The risk or severity of adverse effects can be increased when Desflurane is combined with Amisulpride. | Approved, Investigational |
| Amitriptyline | The risk or severity of adverse effects can be increased when Desflurane is combined with Amitriptyline. | Approved |
| Amlodipine | The risk or severity of adverse effects can be increased when Amlodipine is combined with Desflurane. | Approved |
| Amobarbital | The risk or severity of adverse effects can be increased when Desflurane is combined with Amobarbital. | Approved, Illicit |
| Amoxapine | The risk or severity of adverse effects can be increased when Desflurane is combined with Amoxapine. | Approved |
| Amperozide | The risk or severity of adverse effects can be increased when Desflurane is combined with Amperozide. | Experimental |
| Amphotericin B | The risk or severity of adverse effects can be increased when Amphotericin B is combined with Desflurane. | Approved, Investigational |
| Amyl Nitrite | The risk or severity of adverse effects can be increased when Amyl Nitrite is combined with Desflurane. | Approved |
| Anagrelide | Desflurane may increase the QTc-prolonging activities of Anagrelide. | Approved |
| Apomorphine | The risk or severity of adverse effects can be increased when Apomorphine is combined with Desflurane. | Approved, Investigational |
| Apraclonidine | The risk or severity of adverse effects can be increased when Apraclonidine is combined with Desflurane. | Approved |
| Aripiprazole | Aripiprazole may increase the hypotensive activities of Desflurane. | Approved, Investigational |
| Arotinolol | The risk or severity of adverse effects can be increased when Arotinolol is combined with Desflurane. | Approved |
| Arsenic trioxide | Desflurane may increase the QTc-prolonging activities of Arsenic trioxide. | Approved, Investigational |
| Artemether | Desflurane may increase the QTc-prolonging activities of Artemether. | Approved |
| Articaine | The risk or severity of adverse effects can be increased when Desflurane is combined with Articaine. | Approved |
| Asenapine | Desflurane may increase the QTc-prolonging activities of Asenapine. | Approved |
| Atenolol | The risk or severity of adverse effects can be increased when Atenolol is combined with Desflurane. | Approved |
| Atracurium besylate | Desflurane may increase the neuromuscular blocking activities of Atracurium besylate. | Approved |
| Azelastine | Desflurane may increase the central nervous system depressant (CNS depressant) activities of Azelastine. | Approved |
| Azelastine | The risk or severity of adverse effects can be increased when Desflurane is combined with Azelastine. | Approved |
| Azilsartan medoxomil | The risk or severity of adverse effects can be increased when Azilsartan medoxomil is combined with Desflurane. | Approved |
| Azithromycin | Desflurane may increase the QTc-prolonging activities of Azithromycin. | Approved |
| Baclofen | The risk or severity of adverse effects can be increased when Desflurane is combined with Baclofen. | Approved |
| Barbexaclone | Barbexaclone may increase the hypotensive activities of Desflurane. | Experimental |
| Barbital | The risk or severity of adverse effects can be increased when Desflurane is combined with Barbital. | Illicit |
| Barnidipine | The risk or severity of adverse effects can be increased when Barnidipine is combined with Desflurane. | Approved |
| Bedaquiline | Desflurane may increase the QTc-prolonging activities of Bedaquiline. | Approved |
| Benazepril | The risk or severity of adverse effects can be increased when Benazepril is combined with Desflurane. | Approved, Investigational |
| Bendroflumethiazide | The risk or severity of adverse effects can be increased when Bendroflumethiazide is combined with Desflurane. | Approved |
| Benperidol | The risk or severity of adverse effects can be increased when Desflurane is combined with Benperidol. | Investigational |
| Benzocaine | The risk or severity of adverse effects can be increased when Benzocaine is combined with Desflurane. | Approved |
| Benzyl alcohol | The risk or severity of adverse effects can be increased when Desflurane is combined with Benzyl alcohol. | Approved |
| Bepridil | The risk or severity of adverse effects can be increased when Bepridil is combined with Desflurane. | Approved, Withdrawn |
| Betaxolol | The risk or severity of adverse effects can be increased when Betaxolol is combined with Desflurane. | Approved |
| Bisoprolol | The risk or severity of adverse effects can be increased when Bisoprolol is combined with Desflurane. | Approved |
| Bortezomib | The risk or severity of adverse effects can be increased when Bortezomib is combined with Desflurane. | Approved, Investigational |
| Bretylium | The risk or severity of adverse effects can be increased when Bretylium is combined with Desflurane. | Approved |
| Brexpiprazole | The risk or severity of adverse effects can be increased when Desflurane is combined with Brexpiprazole. | Approved |
| Brimonidine | The risk or severity of adverse effects can be increased when Desflurane is combined with Brimonidine. | Approved |
| Brimonidine | Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Desflurane. | Approved |
| Bromazepam | The risk or severity of adverse effects can be increased when Desflurane is combined with Bromazepam. | Approved, Illicit |
| Bromocriptine | The risk or severity of adverse effects can be increased when Bromocriptine is combined with Desflurane. | Approved, Investigational |
| Brompheniramine | The risk or severity of adverse effects can be increased when Desflurane is combined with Brompheniramine. | Approved |
| Brotizolam | The risk or severity of adverse effects can be increased when Desflurane is combined with Brotizolam. | Approved, Withdrawn |
| Bumetanide | The risk or severity of adverse effects can be increased when Bumetanide is combined with Desflurane. | Approved |
| Bupivacaine | The risk or severity of adverse effects can be increased when Bupivacaine is combined with Desflurane. | Approved, Investigational |
| Buprenorphine | Desflurane may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine. | Approved, Illicit, Investigational, Vet Approved |
| Buspirone | The risk or severity of adverse effects can be increased when Buspirone is combined with Desflurane. | Approved, Investigational |
| Butabarbital | The risk or severity of adverse effects can be increased when Butabarbital is combined with Desflurane. | Approved, Illicit |
| Butalbital | The risk or severity of adverse effects can be increased when Desflurane is combined with Butalbital. | Approved, Illicit |
| Butethal | The risk or severity of adverse effects can be increased when Desflurane is combined with Butethal. | Approved, Illicit |
| Butorphanol | The risk or severity of adverse effects can be increased when Butorphanol is combined with Desflurane. | Approved, Illicit, Vet Approved |
| Canagliflozin | The risk or severity of adverse effects can be increased when Canagliflozin is combined with Desflurane. | Approved |
| Candesartan | The risk or severity of adverse effects can be increased when Candesartan is combined with Desflurane. | Approved |
| Captopril | The risk or severity of adverse effects can be increased when Captopril is combined with Desflurane. | Approved |
| Carbamazepine | The risk or severity of adverse effects can be increased when Carbamazepine is combined with Desflurane. | Approved, Investigational |
| Carbetocin | The risk or severity of adverse effects can be increased when Carbetocin is combined with Desflurane. | Approved |
| Carbinoxamine | The risk or severity of adverse effects can be increased when Desflurane is combined with Carbinoxamine. | Approved |
| Carfentanil | The risk or severity of adverse effects can be increased when Desflurane is combined with Carfentanil. | Illicit, Vet Approved |
| Carisoprodol | The risk or severity of adverse effects can be increased when Desflurane is combined with Carisoprodol. | Approved |
| Carteolol | The risk or severity of adverse effects can be increased when Carteolol is combined with Desflurane. | Approved |
| Carvedilol | The risk or severity of adverse effects can be increased when Carvedilol is combined with Desflurane. | Approved, Investigational |
| Ceritinib | Desflurane may increase the QTc-prolonging activities of Ceritinib. | Approved |
| Cetirizine | The risk or severity of adverse effects can be increased when Desflurane is combined with Cetirizine. | Approved |
| Chloral hydrate | The risk or severity of adverse effects can be increased when Desflurane is combined with Chloral hydrate. | Approved, Illicit, Vet Approved |
| Chlordiazepoxide | The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Desflurane. | Approved, Illicit |
| Chlormezanone | The risk or severity of adverse effects can be increased when Chlormezanone is combined with Desflurane. | Approved, Withdrawn |
| Chloroprocaine | The risk or severity of adverse effects can be increased when Chloroprocaine is combined with Desflurane. | Approved |
| Chloroquine | Desflurane may increase the QTc-prolonging activities of Chloroquine. | Approved, Vet Approved |
| Chlorothiazide | The risk or severity of adverse effects can be increased when Chlorothiazide is combined with Desflurane. | Approved, Vet Approved |
| Chlorphenamine | The risk or severity of adverse effects can be increased when Desflurane is combined with Chlorphenamine. | Approved |
| Chlorpromazine | Desflurane may increase the QTc-prolonging activities of Chlorpromazine. | Approved, Vet Approved |
| Chlorprothixene | The risk or severity of adverse effects can be increased when Desflurane is combined with Chlorprothixene. | Approved, Withdrawn |
| Chlorthalidone | The risk or severity of adverse effects can be increased when Chlorthalidone is combined with Desflurane. | Approved |
| Chlorzoxazone | The risk or severity of adverse effects can be increased when Desflurane is combined with Chlorzoxazone. | Approved |
| Cilazapril | The risk or severity of adverse effects can be increased when Cilazapril is combined with Desflurane. | Approved |
| Cilnidipine | The risk or severity of adverse effects can be increased when Cilnidipine is combined with Desflurane. | Approved |
| Cinchocaine | The risk or severity of adverse effects can be increased when Cinchocaine is combined with Desflurane. | Approved, Vet Approved |
| Ciprofloxacin | Desflurane may increase the QTc-prolonging activities of Ciprofloxacin. | Approved, Investigational |
| Cisapride | Desflurane may increase the QTc-prolonging activities of Cisapride. | Approved, Investigational, Withdrawn |
| Citalopram | Desflurane may increase the QTc-prolonging activities of Citalopram. | Approved |
| Clarithromycin | Desflurane may increase the QTc-prolonging activities of Clarithromycin. | Approved |
| Clemastine | The risk or severity of adverse effects can be increased when Desflurane is combined with Clemastine. | Approved |
| Clevidipine | The risk or severity of adverse effects can be increased when Clevidipine is combined with Desflurane. | Approved |
| Clidinium | The risk or severity of adverse effects can be increased when Desflurane is combined with Clidinium. | Approved |
| Clobazam | The risk or severity of adverse effects can be increased when Desflurane is combined with Clobazam. | Approved, Illicit |
| Clofarabine | The risk or severity of adverse effects can be increased when Clofarabine is combined with Desflurane. | Approved, Investigational |
| Clomipramine | The risk or severity of adverse effects can be increased when Desflurane is combined with Clomipramine. | Approved, Vet Approved |
| Clonazepam | The risk or severity of adverse effects can be increased when Desflurane is combined with Clonazepam. | Approved, Illicit |
| Clonidine | The risk or severity of adverse effects can be increased when Desflurane is combined with Clonidine. | Approved |
| Clorazepate | The risk or severity of adverse effects can be increased when Clorazepate is combined with Desflurane. | Approved, Illicit |
| Clozapine | Desflurane may increase the QTc-prolonging activities of Clozapine. | Approved |
| Cocaine | The risk or severity of adverse effects can be increased when Cocaine is combined with Desflurane. | Approved, Illicit |
| Codeine | The risk or severity of adverse effects can be increased when Codeine is combined with Desflurane. | Approved, Illicit |
| Conivaptan | The risk or severity of adverse effects can be increased when Conivaptan is combined with Desflurane. | Approved, Investigational |
| Crizotinib | Desflurane may increase the QTc-prolonging activities of Crizotinib. | Approved |
| Cyclizine | The risk or severity of adverse effects can be increased when Desflurane is combined with Cyclizine. | Approved |
| Cyclobenzaprine | The risk or severity of adverse effects can be increased when Cyclobenzaprine is combined with Desflurane. | Approved |
| Cyproheptadine | The risk or severity of adverse effects can be increased when Desflurane is combined with Cyproheptadine. | Approved |
| Dantrolene | The risk or severity of adverse effects can be increased when Desflurane is combined with Dantrolene. | Approved |
| Dapagliflozin | The risk or severity of adverse effects can be increased when Dapagliflozin is combined with Desflurane. | Approved |
| Dapiprazole | The risk or severity of adverse effects can be increased when Dapiprazole is combined with Desflurane. | Approved |
| Dapoxetine | The risk or severity of adverse effects can be increased when Desflurane is combined with Dapoxetine. | Investigational |
| Deramciclane | The risk or severity of adverse effects can be increased when Desflurane is combined with deramciclane. | Investigational |
| Desipramine | The risk or severity of adverse effects can be increased when Desflurane is combined with Desipramine. | Approved |
| Desloratadine | The risk or severity of adverse effects can be increased when Desflurane is combined with Desloratadine. | Approved, Investigational |
| Desvenlafaxine | The risk or severity of adverse effects can be increased when Desflurane is combined with Desvenlafaxine. | Approved |
| Dexbrompheniramine | The risk or severity of adverse effects can be increased when Desflurane is combined with Dexbrompheniramine. | Approved |
| Dexmedetomidine | The risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Desflurane. | Approved, Vet Approved |
| Dextromoramide | The risk or severity of adverse effects can be increased when Desflurane is combined with Dextromoramide. | Experimental, Illicit |
| Dextropropoxyphene | The risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Desflurane. | Approved, Illicit, Withdrawn |
| Dezocine | The risk or severity of adverse effects can be increased when Desflurane is combined with Dezocine. | Approved |
| Diazepam | The risk or severity of adverse effects can be increased when Diazepam is combined with Desflurane. | Approved, Illicit, Vet Approved |
| Diclofenamide | The risk or severity of adverse effects can be increased when Diclofenamide is combined with Desflurane. | Approved |
| Difenoxin | The risk or severity of adverse effects can be increased when Desflurane is combined with Difenoxin. | Approved, Illicit |
| Dihydrocodeine | The risk or severity of adverse effects can be increased when Desflurane is combined with Dihydrocodeine. | Approved, Illicit |
| Dihydroetorphine | The risk or severity of adverse effects can be increased when Desflurane is combined with Dihydroetorphine. | Experimental, Illicit |
| Dihydromorphine | The risk or severity of adverse effects can be increased when Desflurane is combined with Dihydromorphine. | Experimental, Illicit |
| Diltiazem | The risk or severity of adverse effects can be increased when Diltiazem is combined with Desflurane. | Approved |
| Dimenhydrinate | The risk or severity of adverse effects can be increased when Desflurane is combined with Dimenhydrinate. | Approved |
| Dinutuximab | The risk or severity of adverse effects can be increased when Dinutuximab is combined with Desflurane. | Approved |
| Diphenhydramine | The risk or severity of adverse effects can be increased when Diphenhydramine is combined with Desflurane. | Approved |
| Diphenoxylate | The risk or severity of adverse effects can be increased when Diphenoxylate is combined with Desflurane. | Approved, Illicit |
| Dipyridamole | The risk or severity of adverse effects can be increased when Dipyridamole is combined with Desflurane. | Approved |
| Disopyramide | Desflurane may increase the QTc-prolonging activities of Disopyramide. | Approved |
| Dofetilide | Desflurane may increase the QTc-prolonging activities of Dofetilide. | Approved |
| Dolasetron | Desflurane may increase the QTc-prolonging activities of Dolasetron. | Approved |
| Domperidone | Desflurane may increase the QTc-prolonging activities of Domperidone. | Approved, Investigational, Vet Approved |
| Dopamine | Desflurane may increase the arrhythmogenic activities of Dopamine. | Approved |
| Doxazosin | The risk or severity of adverse effects can be increased when Doxazosin is combined with Desflurane. | Approved |
| Doxepin | The risk or severity of adverse effects can be increased when Desflurane is combined with Doxepin. | Approved |
| Doxylamine | Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Desflurane. | Approved, Vet Approved |
| Dronabinol | Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Desflurane. | Approved, Illicit |
| Dronedarone | Desflurane may increase the QTc-prolonging activities of Dronedarone. | Approved |
| Droperidol | Droperidol may increase the central nervous system depressant (CNS depressant) activities of Desflurane. | Approved, Vet Approved |
| Drotebanol | The risk or severity of adverse effects can be increased when Desflurane is combined with Drotebanol. | Experimental, Illicit |
| Duloxetine | Desflurane may increase the orthostatic hypotensive activities of Duloxetine. | Approved |
| Dyclonine | The risk or severity of adverse effects can be increased when Dyclonine is combined with Desflurane. | Approved |
| Ecgonine | The risk or severity of adverse effects can be increased when Desflurane is combined with Ecgonine. | Experimental, Illicit |
| Ecopipam | The risk or severity of adverse effects can be increased when Desflurane is combined with Ecopipam. | Investigational |
| Efavirenz | The risk or severity of adverse effects can be increased when Desflurane is combined with Efavirenz. | Approved, Investigational |
| Efonidipine | The risk or severity of adverse effects can be increased when Desflurane is combined with Efonidipine. | Approved |
| Eliglustat | Desflurane may increase the QTc-prolonging activities of Eliglustat. | Approved |
| Eltanolone | The risk or severity of adverse effects can be increased when Desflurane is combined with Pregnanolone. | Investigational |
| Empagliflozin | The risk or severity of adverse effects can be increased when Empagliflozin is combined with Desflurane. | Approved |
| Enalapril | The risk or severity of adverse effects can be increased when Enalapril is combined with Desflurane. | Approved, Vet Approved |
| Enalaprilat | The risk or severity of adverse effects can be increased when Desflurane is combined with Enalaprilat. | Approved |
| Enflurane | The risk or severity of adverse effects can be increased when Enflurane is combined with Desflurane. | Approved, Vet Approved |
| Entacapone | The risk or severity of adverse effects can be increased when Desflurane is combined with Entacapone. | Approved, Investigational |
| Ephedra | Ephedra may increase the arrhythmogenic activities of Desflurane. | Approved, Nutraceutical, Withdrawn |
| Ephedrine | Ephedrine may increase the arrhythmogenic activities of Desflurane. | Approved |
| Epinephrine | Desflurane may increase the arrhythmogenic activities of Epinephrine. | Approved, Vet Approved |
| Eplerenone | The risk or severity of adverse effects can be increased when Eplerenone is combined with Desflurane. | Approved |
| Epoprostenol | The risk or severity of adverse effects can be increased when Desflurane is combined with Epoprostenol. | Approved |
| Eprosartan | The risk or severity of adverse effects can be increased when Eprosartan is combined with Desflurane. | Approved |
| Erythromycin | Desflurane may increase the QTc-prolonging activities of Erythromycin. | Approved, Vet Approved |
| Escitalopram | Desflurane may increase the QTc-prolonging activities of Escitalopram. | Approved, Investigational |
| Esmolol | The risk or severity of adverse effects can be increased when Esmolol is combined with Desflurane. | Approved |
| Estazolam | The risk or severity of adverse effects can be increased when Desflurane is combined with Estazolam. | Approved, Illicit |
| Eszopiclone | The risk or severity of adverse effects can be increased when Eszopiclone is combined with Desflurane. | Approved |
| Etacrynic acid | The risk or severity of adverse effects can be increased when Etacrynic acid is combined with Desflurane. | Approved |
| Ethanol | Desflurane may increase the central nervous system depressant (CNS depressant) activities of Ethanol. | Approved |
| Ethchlorvynol | The risk or severity of adverse effects can be increased when Ethchlorvynol is combined with Desflurane. | Approved, Illicit, Withdrawn |
| Ethosuximide | The risk or severity of adverse effects can be increased when Desflurane is combined with Ethosuximide. | Approved |
| Ethotoin | The risk or severity of adverse effects can be increased when Desflurane is combined with Ethotoin. | Approved |
| Ethyl carbamate | The risk or severity of adverse effects can be increased when Desflurane is combined with Ethyl carbamate. | Withdrawn |
| Ethyl loflazepate | The risk or severity of adverse effects can be increased when Desflurane is combined with Ethyl loflazepate. | Approved, Illicit |
| Ethylmorphine | The risk or severity of adverse effects can be increased when Desflurane is combined with Ethylmorphine. | Approved, Illicit |
| Etidocaine | The risk or severity of adverse effects can be increased when Desflurane is combined with Etidocaine. | Approved |
| Etifoxine | The risk or severity of adverse effects can be increased when Desflurane is combined with Etifoxine. | Withdrawn |
| Etizolam | The risk or severity of adverse effects can be increased when Desflurane is combined with Etizolam. | Approved |
| Etomidate | The risk or severity of adverse effects can be increased when Etomidate is combined with Desflurane. | Approved |
| Etoperidone | The risk or severity of adverse effects can be increased when Desflurane is combined with Etoperidone. | Approved |
| Etorphine | The risk or severity of adverse effects can be increased when Desflurane is combined with Etorphine. | Illicit, Vet Approved |
| Ezogabine | The risk or severity of adverse effects can be increased when Desflurane is combined with Ezogabine. | Approved |
| Felbamate | The risk or severity of adverse effects can be increased when Desflurane is combined with Felbamate. | Approved |
| Felodipine | The risk or severity of adverse effects can be increased when Felodipine is combined with Desflurane. | Approved, Investigational |
| Fencamfamine | The risk or severity of adverse effects can be increased when Desflurane is combined with Fencamfamine. | Approved, Illicit, Withdrawn |
| Fenoldopam | The risk or severity of adverse effects can be increased when Desflurane is combined with Fenoldopam. | Approved |
| Fentanyl | The risk or severity of adverse effects can be increased when Fentanyl is combined with Desflurane. | Approved, Illicit, Investigational, Vet Approved |
| Fexofenadine | The risk or severity of adverse effects can be increased when Desflurane is combined with Fexofenadine. | Approved |
| Fimasartan | The risk or severity of adverse effects can be increased when Desflurane is combined with Fimasartan. | Approved |
| Flecainide | Desflurane may increase the QTc-prolonging activities of Flecainide. | Approved, Withdrawn |
| Flibanserin | The risk or severity of adverse effects can be increased when Desflurane is combined with Flibanserin. | Approved |
| Fludiazepam | The risk or severity of adverse effects can be increased when Desflurane is combined with Fludiazepam. | Approved, Illicit |
| Flunarizine | The risk or severity of adverse effects can be increased when Desflurane is combined with Flunarizine. | Approved |
| Flunitrazepam | The risk or severity of adverse effects can be increased when Desflurane is combined with Flunitrazepam. | Approved, Illicit |
| Fluoxetine | Desflurane may increase the QTc-prolonging activities of Fluoxetine. | Approved, Vet Approved |
| Flupentixol | Desflurane may increase the QTc-prolonging activities of Flupentixol. | Approved, Withdrawn |
| Fluphenazine | The risk or severity of adverse effects can be increased when Fluphenazine is combined with Desflurane. | Approved |
| Flurazepam | The risk or severity of adverse effects can be increased when Flurazepam is combined with Desflurane. | Approved, Illicit |
| Fluspirilene | The risk or severity of adverse effects can be increased when Desflurane is combined with Fluspirilene. | Approved |
| Fluticasone propionate | The risk or severity of adverse effects can be increased when Desflurane is combined with Fluticasone Propionate. | Approved |
| Fluvoxamine | The risk or severity of adverse effects can be increased when Fluvoxamine is combined with Desflurane. | Approved, Investigational |
| Formoterol | Desflurane may increase the arrhythmogenic activities of Formoterol. | Approved, Investigational |
| Fosinopril | The risk or severity of adverse effects can be increased when Fosinopril is combined with Desflurane. | Approved |
| Fosphenytoin | The risk or severity of adverse effects can be increased when Desflurane is combined with Fosphenytoin. | Approved |
| Fospropofol | The risk or severity of adverse effects can be increased when Desflurane is combined with Fospropofol. | Approved, Illicit |
| Furosemide | The risk or severity of adverse effects can be increased when Furosemide is combined with Desflurane. | Approved, Vet Approved |
| Gabapentin | The risk or severity of adverse effects can be increased when Gabapentin is combined with Desflurane. | Approved, Investigational |
| Gabapentin Enacarbil | The risk or severity of adverse effects can be increased when Desflurane is combined with gabapentin enacarbil. | Approved |
| Gadobenic acid | Desflurane may increase the QTc-prolonging activities of Gadobenic acid. | Approved |
| Gamma Hydroxybutyric Acid | The risk or severity of adverse effects can be increased when Desflurane is combined with Gamma Hydroxybutyric Acid. | Approved, Illicit |
| Gemifloxacin | Desflurane may increase the QTc-prolonging activities of Gemifloxacin. | Approved, Investigational |
| Gepirone | The risk or severity of adverse effects can be increased when Desflurane is combined with Gepirone. | Investigational |
| Glutethimide | The risk or severity of adverse effects can be increased when Desflurane is combined with Glutethimide. | Approved, Illicit |
| Goserelin | Desflurane may increase the QTc-prolonging activities of Goserelin. | Approved |
| Granisetron | Desflurane may increase the QTc-prolonging activities of Granisetron. | Approved, Investigational |
| Guanfacine | The risk or severity of adverse effects can be increased when Desflurane is combined with Guanfacine. | Approved, Investigational |
| Halazepam | The risk or severity of adverse effects can be increased when Halazepam is combined with Desflurane. | Approved, Illicit, Withdrawn |
| Haloperidol | Desflurane may increase the QTc-prolonging activities of Haloperidol. | Approved |
| Halothane | The risk or severity of adverse effects can be increased when Halothane is combined with Desflurane. | Approved, Vet Approved |
| Heroin | The risk or severity of adverse effects can be increased when Desflurane is combined with Heroin. | Approved, Illicit |
| Hexobarbital | The risk or severity of adverse effects can be increased when Desflurane is combined with Hexobarbital. | Approved |
| Hydralazine | The risk or severity of adverse effects can be increased when Hydralazine is combined with Desflurane. | Approved |
| Hydrochlorothiazide | The risk or severity of adverse effects can be increased when Hydrochlorothiazide is combined with Desflurane. | Approved, Vet Approved |
| Hydrocodone | Desflurane may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. | Approved, Illicit |
| Hydroflumethiazide | The risk or severity of adverse effects can be increased when Desflurane is combined with Hydroflumethiazide. | Approved |
| Hydromorphone | The risk or severity of adverse effects can be increased when Hydromorphone is combined with Desflurane. | Approved, Illicit |
| Hydroxyzine | Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Desflurane. | Approved |
| Ibutilide | Desflurane may increase the QTc-prolonging activities of Ibutilide. | Approved |
| Iloperidone | Desflurane may increase the QTc-prolonging activities of Iloperidone. | Approved |
| Iloprost | The risk or severity of adverse effects can be increased when Desflurane is combined with Iloprost. | Approved, Investigational |
| Imidapril | The risk or severity of adverse effects can be increased when Desflurane is combined with Imidapril. | Investigational |
| Imipramine | The risk or severity of adverse effects can be increased when Desflurane is combined with Imipramine. | Approved |
| Indalpine | The risk or severity of adverse effects can be increased when Desflurane is combined with Indalpine. | Investigational, Withdrawn |
| Indapamide | The risk or severity of adverse effects can be increased when Indapamide is combined with Desflurane. | Approved |
| Indoramin | The risk or severity of adverse effects can be increased when Desflurane is combined with Indoramin. | Withdrawn |
| Irbesartan | The risk or severity of adverse effects can be increased when Irbesartan is combined with Desflurane. | Approved, Investigational |
| Isocarboxazid | The risk or severity of adverse effects can be increased when Desflurane is combined with Isocarboxazid. | Approved |
| Isoflurane | The risk or severity of adverse effects can be increased when Isoflurane is combined with Desflurane. | Approved, Vet Approved |
| Isoprenaline | Desflurane may increase the arrhythmogenic activities of Isoprenaline. | Approved |
| Isosorbide Dinitrate | The risk or severity of adverse effects can be increased when Isosorbide Dinitrate is combined with Desflurane. | Approved |
| Isosorbide Mononitrate | The risk or severity of adverse effects can be increased when Isosorbide Mononitrate is combined with Desflurane. | Approved |
| Isoxsuprine | The risk or severity of adverse effects can be increased when Isoxsuprine is combined with Desflurane. | Approved, Withdrawn |
| Isradipine | The risk or severity of adverse effects can be increased when Isradipine is combined with Desflurane. | Approved |
| Ketamine | The risk or severity of adverse effects can be increased when Desflurane is combined with Ketamine. | Approved, Vet Approved |
| Ketazolam | The risk or severity of adverse effects can be increased when Desflurane is combined with Ketazolam. | Approved |
| Ketobemidone | The risk or severity of adverse effects can be increased when Desflurane is combined with Ketobemidone. | Approved |
| Labetalol | The risk or severity of adverse effects can be increased when Labetalol is combined with Desflurane. | Approved |
| Lacidipine | The risk or severity of adverse effects can be increased when Desflurane is combined with Lacidipine. | Approved |
| Lamotrigine | The risk or severity of adverse effects can be increased when Desflurane is combined with Lamotrigine. | Approved, Investigational |
| Lenvatinib | Desflurane may increase the QTc-prolonging activities of Lenvatinib. | Approved |
| Lercanidipine | The risk or severity of adverse effects can be increased when Desflurane is combined with Lercanidipine. | Approved, Investigational |
| Leuprolide | Desflurane may increase the QTc-prolonging activities of Leuprolide. | Approved, Investigational |
| Levetiracetam | The risk or severity of adverse effects can be increased when Desflurane is combined with Levetiracetam. | Approved, Investigational |
| Levobunolol | The risk or severity of adverse effects can be increased when Levobunolol is combined with Desflurane. | Approved |
| Levobupivacaine | The risk or severity of adverse effects can be increased when Levobupivacaine is combined with Desflurane. | Approved |
| Levocabastine | The risk or severity of adverse effects can be increased when Desflurane is combined with Levocabastine. | Approved |
| Levocetirizine | The risk or severity of adverse effects can be increased when Desflurane is combined with Levocetirizine. | Approved |
| Levodopa | Desflurane may increase the orthostatic hypotensive activities of Levodopa. | Approved |
| Levofloxacin | Desflurane may increase the QTc-prolonging activities of Levofloxacin. | Approved, Investigational |
| Levomethadyl Acetate | The risk or severity of adverse effects can be increased when Desflurane is combined with Levomethadyl Acetate. | Approved |
| Levomilnacipran | The risk or severity of adverse effects can be increased when Desflurane is combined with Levomilnacipran. | Approved |
| Levorphanol | The risk or severity of adverse effects can be increased when Levorphanol is combined with Desflurane. | Approved |
| Levosimendan | The risk or severity of adverse effects can be increased when Desflurane is combined with Levosimendan. | Approved, Investigational |
| Lidocaine | The risk or severity of adverse effects can be increased when Lidocaine is combined with Desflurane. | Approved, Vet Approved |
| Lisinopril | The risk or severity of adverse effects can be increased when Lisinopril is combined with Desflurane. | Approved, Investigational |
| Lithium | The risk or severity of adverse effects can be increased when Desflurane is combined with Lithium. | Approved |
| Lofentanil | The risk or severity of adverse effects can be increased when Desflurane is combined with Lofentanil. | Illicit |
| Lofexidine | The risk or severity of adverse effects can be increased when Desflurane is combined with Lofexidine. | Approved, Investigational |
| Lopinavir | Desflurane may increase the QTc-prolonging activities of Lopinavir. | Approved |
| Loratadine | The risk or severity of adverse effects can be increased when Desflurane is combined with Loratadine. | Approved |
| Lorazepam | The risk or severity of adverse effects can be increased when Lorazepam is combined with Desflurane. | Approved |
| Losartan | The risk or severity of adverse effects can be increased when Losartan is combined with Desflurane. | Approved |
| Loxapine | The risk or severity of adverse effects can be increased when Loxapine is combined with Desflurane. | Approved |
| Lumefantrine | Desflurane may increase the QTc-prolonging activities of Lumefantrine. | Approved |
| Lurasidone | The risk or severity of adverse effects can be increased when Desflurane is combined with Lurasidone. | Approved |
| Magnesium Sulfate | Magnesium Sulfate may increase the central nervous system depressant (CNS depressant) activities of Desflurane. | Approved, Vet Approved |
| Mannitol | The risk or severity of adverse effects can be increased when Mannitol is combined with Desflurane. | Approved, Investigational |
| Maprotiline | The risk or severity of adverse effects can be increased when Desflurane is combined with Maprotiline. | Approved |
| Mecamylamine | The risk or severity of adverse effects can be increased when Mecamylamine is combined with Desflurane. | Approved |
| Meclizine | The risk or severity of adverse effects can be increased when Desflurane is combined with Meclizine. | Approved |
| Melatonin | The risk or severity of adverse effects can be increased when Melatonin is combined with Desflurane. | Approved, Nutraceutical, Vet Approved |
| Melperone | The risk or severity of adverse effects can be increased when Desflurane is combined with Melperone. | Approved |
| Mepivacaine | The risk or severity of adverse effects can be increased when Mepivacaine is combined with Desflurane. | Approved, Vet Approved |
| Meprobamate | The risk or severity of adverse effects can be increased when Meprobamate is combined with Desflurane. | Approved, Illicit |
| Mesoridazine | The risk or severity of adverse effects can be increased when Mesoridazine is combined with Desflurane. | Approved |
| Metaxalone | The risk or severity of adverse effects can be increased when Desflurane is combined with Metaxalone. | Approved |
| Methadone | Desflurane may increase the QTc-prolonging activities of Methadone. | Approved |
| Methadyl Acetate | The risk or severity of adverse effects can be increased when Desflurane is combined with Methadyl Acetate. | Approved, Illicit |
| Methapyrilene | The risk or severity of adverse effects can be increased when Desflurane is combined with Methapyrilene. | Withdrawn |
| Methaqualone | The risk or severity of adverse effects can be increased when Desflurane is combined with Methaqualone. | Illicit, Withdrawn |
| Methazolamide | The risk or severity of adverse effects can be increased when Methazolamide is combined with Desflurane. | Approved |
| Methocarbamol | The risk or severity of adverse effects can be increased when Desflurane is combined with Methocarbamol. | Approved, Vet Approved |
| Methohexital | The risk or severity of adverse effects can be increased when Methohexital is combined with Desflurane. | Approved |
| Methotrimeprazine | Desflurane may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine. | Approved |
| Methoxyflurane | The risk or severity of adverse effects can be increased when Methoxyflurane is combined with Desflurane. | Approved, Vet Approved |
| Methsuximide | The risk or severity of adverse effects can be increased when Desflurane is combined with Methsuximide. | Approved |
| Methyclothiazide | The risk or severity of adverse effects can be increased when Methyclothiazide is combined with Desflurane. | Approved |
| Methyldopa | The risk or severity of adverse effects can be increased when Methyldopa is combined with Desflurane. | Approved |
| Methylecgonine | The risk or severity of adverse effects can be increased when Desflurane is combined with ECGONINE METHYL ESTER. | Experimental |
| Methylphenidate | Methylphenidate may increase the hypertensive activities of Desflurane. | Approved, Investigational |
| Methylphenobarbital | The risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Desflurane. | Approved |
| Metipranolol | The risk or severity of adverse effects can be increased when Metipranolol is combined with Desflurane. | Approved |
| Metolazone | The risk or severity of adverse effects can be increased when Metolazone is combined with Desflurane. | Approved |
| Metoprolol | The risk or severity of adverse effects can be increased when Metoprolol is combined with Desflurane. | Approved, Investigational |
| Metyrosine | Desflurane may increase the sedative activities of Metyrosine. | Approved |
| Midazolam | The risk or severity of adverse effects can be increased when Midazolam is combined with Desflurane. | Approved, Illicit |
| Mifepristone | Mifepristone may increase the QTc-prolonging activities of Desflurane. | Approved, Investigational |
| Milnacipran | The risk or severity of adverse effects can be increased when Desflurane is combined with Milnacipran. | Approved |
| Minocycline | Minocycline may increase the central nervous system depressant (CNS depressant) activities of Desflurane. | Approved, Investigational |
| Minoxidil | The risk or severity of adverse effects can be increased when Minoxidil is combined with Desflurane. | Approved |
| Mirtazapine | Desflurane may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine. | Approved |
| Mivacurium | Desflurane may increase the neuromuscular blocking activities of Mivacurium. | Approved |
| Moexipril | The risk or severity of adverse effects can be increased when Moexipril is combined with Desflurane. | Approved |
| Molindone | The risk or severity of adverse effects can be increased when Desflurane is combined with Molindone. | Approved |
| Morphine | The risk or severity of adverse effects can be increased when Morphine is combined with Desflurane. | Approved, Investigational |
| Moxifloxacin | Desflurane may increase the QTc-prolonging activities of Moxifloxacin. | Approved, Investigational |
| Moxonidine | The risk or severity of adverse effects can be increased when Desflurane is combined with Moxonidine. | Approved |
| Nabilone | Nabilone may increase the central nervous system depressant (CNS depressant) activities of Desflurane. | Approved, Investigational |
| Nadolol | The risk or severity of adverse effects can be increased when Nadolol is combined with Desflurane. | Approved |
| Nalbuphine | The risk or severity of adverse effects can be increased when Nalbuphine is combined with Desflurane. | Approved |
| Nebivolol | The risk or severity of adverse effects can be increased when Nebivolol is combined with Desflurane. | Approved, Investigational |
| Nefazodone | The risk or severity of adverse effects can be increased when Desflurane is combined with Nefazodone. | Approved, Withdrawn |
| Nesiritide | The risk or severity of adverse effects can be increased when Nesiritide is combined with Desflurane. | Approved, Investigational |
| Nicardipine | The risk or severity of adverse effects can be increased when Nicardipine is combined with Desflurane. | Approved |
| Nicorandil | Nicorandil may increase the hypotensive activities of Desflurane. | Approved |
| Nifedipine | The risk or severity of adverse effects can be increased when Nifedipine is combined with Desflurane. | Approved |
| Nilotinib | Desflurane may increase the QTc-prolonging activities of Nilotinib. | Approved, Investigational |
| Nilvadipine | The risk or severity of adverse effects can be increased when Desflurane is combined with Nilvadipine. | Approved |
| Nimodipine | The risk or severity of adverse effects can be increased when Nimodipine is combined with Desflurane. | Approved |
| Nisoldipine | The risk or severity of adverse effects can be increased when Nisoldipine is combined with Desflurane. | Approved |
| Nitrazepam | The risk or severity of adverse effects can be increased when Desflurane is combined with Nitrazepam. | Approved |
| Nitrendipine | The risk or severity of adverse effects can be increased when Desflurane is combined with Nitrendipine. | Approved |
| Nitric Oxide | The risk or severity of adverse effects can be increased when Desflurane is combined with Nitric Oxide. | Approved |
| Nitroglycerin | The risk or severity of adverse effects can be increased when Nitroglycerin is combined with Desflurane. | Approved, Investigational |
| Nitroprusside | The risk or severity of adverse effects can be increased when Nitroprusside is combined with Desflurane. | Approved |
| Nitrous oxide | The risk or severity of adverse effects can be increased when Desflurane is combined with Nitrous oxide. | Approved, Vet Approved |
| Norepinephrine | Desflurane may increase the arrhythmogenic activities of Norepinephrine. | Approved |
| Norflurane | The risk or severity of adverse effects can be increased when Desflurane is combined with 1,1,1,2 Tetrafluoroethane. | Investigational |
| Normethadone | The risk or severity of adverse effects can be increased when Desflurane is combined with Normethadone. | Approved, Illicit |
| Nortriptyline | The risk or severity of adverse effects can be increased when Desflurane is combined with Nortriptyline. | Approved |
| Obinutuzumab | The risk or severity of adverse effects can be increased when Desflurane is combined with Obinutuzumab. | Approved |
| Ofloxacin | Desflurane may increase the QTc-prolonging activities of Ofloxacin. | Approved |
| Olanzapine | The risk or severity of adverse effects can be increased when Olanzapine is combined with Desflurane. | Approved, Investigational |
| Olmesartan | The risk or severity of adverse effects can be increased when Olmesartan is combined with Desflurane. | Approved, Investigational |
| Olopatadine | The risk or severity of adverse effects can be increased when Desflurane is combined with Olopatadine. | Approved |
| Ondansetron | Desflurane may increase the QTc-prolonging activities of Ondansetron. | Approved |
| Opium | The risk or severity of adverse effects can be increased when Desflurane is combined with Opium. | Approved, Illicit |
| Orphenadrine | Desflurane may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine. | Approved |
| Osanetant | The risk or severity of adverse effects can be increased when Desflurane is combined with Osanetant. | Investigational |
| Oxazepam | The risk or severity of adverse effects can be increased when Oxazepam is combined with Desflurane. | Approved |
| Oxethazaine | The risk or severity of adverse effects can be increased when Desflurane is combined with Oxetacaine. | Investigational |
| Oxprenolol | The risk or severity of adverse effects can be increased when Desflurane is combined with Oxprenolol. | Approved |
| Oxybuprocaine | The risk or severity of adverse effects can be increased when Oxybuprocaine is combined with Desflurane. | Approved |
| Oxycodone | The risk or severity of adverse effects can be increased when Oxycodone is combined with Desflurane. | Approved, Illicit, Investigational |
| Oxymorphone | The risk or severity of adverse effects can be increased when Desflurane is combined with Oxymorphone. | Approved, Investigational, Vet Approved |
| Paclitaxel | The risk or severity of adverse effects can be increased when Desflurane is combined with Paclitaxel. | Approved, Vet Approved |
| Paliperidone | Desflurane may increase the QTc-prolonging activities of Paliperidone. | Approved |
| Panobinostat | Desflurane may increase the QTc-prolonging activities of Panobinostat. | Approved, Investigational |
| Papaverine | The risk or severity of adverse effects can be increased when Papaverine is combined with Desflurane. | Approved |
| Paraldehyde | Desflurane may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde. | Approved |
| Paroxetine | The risk or severity of adverse effects can be increased when Desflurane is combined with Paroxetine. | Approved, Investigational |
| Pazopanib | Desflurane may increase the QTc-prolonging activities of Pazopanib. | Approved |
| Penbutolol | The risk or severity of adverse effects can be increased when Penbutolol is combined with Desflurane. | Approved, Investigational |
| Pentamidine | Desflurane may increase the QTc-prolonging activities of Pentamidine. | Approved |
| Pentazocine | The risk or severity of adverse effects can be increased when Pentazocine is combined with Desflurane. | Approved, Vet Approved |
| Pentobarbital | The risk or severity of adverse effects can be increased when Pentobarbital is combined with Desflurane. | Approved, Vet Approved |
| Perampanel | Perampanel may increase the central nervous system depressant (CNS depressant) activities of Desflurane. | Approved |
| Perazine | The risk or severity of adverse effects can be increased when Desflurane is combined with Perazine. | Investigational |
| Perflutren | Desflurane may increase the QTc-prolonging activities of Perflutren. | Approved |
| Perindopril | The risk or severity of adverse effects can be increased when Perindopril is combined with Desflurane. | Approved |
| Perospirone | The risk or severity of adverse effects can be increased when Desflurane is combined with Perospirone. | Approved |
| Perphenazine | The risk or severity of adverse effects can be increased when Perphenazine is combined with Desflurane. | Approved |
| Pethidine | The risk or severity of adverse effects can be increased when Pethidine is combined with Desflurane. | Approved |
| Phenelzine | The risk or severity of adverse effects can be increased when Desflurane is combined with Phenelzine. | Approved |
| Phenobarbital | The risk or severity of adverse effects can be increased when Phenobarbital is combined with Desflurane. | Approved |
| Phenoxybenzamine | The risk or severity of adverse effects can be increased when Desflurane is combined with Phenoxybenzamine. | Approved |
| Phentolamine | The risk or severity of adverse effects can be increased when Desflurane is combined with Phentolamine. | Approved |
| Phenytoin | The risk or severity of adverse effects can be increased when Desflurane is combined with Phenytoin. | Approved, Vet Approved |
| Pimozide | Desflurane may increase the QTc-prolonging activities of Pimozide. | Approved |
| Pindolol | The risk or severity of adverse effects can be increased when Pindolol is combined with Desflurane. | Approved |
| Pipamperone | The risk or severity of adverse effects can be increased when Desflurane is combined with Pipamperone. | Approved |
| Pipotiazine | The risk or severity of adverse effects can be increased when Desflurane is combined with Pipotiazine. | Approved |
| Piritramide | The risk or severity of adverse effects can be increased when Desflurane is combined with Piritramide. | Investigational |
| Pomalidomide | The risk or severity of adverse effects can be increased when Desflurane is combined with Pomalidomide. | Approved |
| Pramipexole | Desflurane may increase the sedative activities of Pramipexole. | Approved, Investigational |
| Pramocaine | The risk or severity of adverse effects can be increased when Desflurane is combined with Pramocaine. | Approved |
| Prazepam | The risk or severity of adverse effects can be increased when Desflurane is combined with Prazepam. | Approved, Illicit |
| Prazosin | The risk or severity of adverse effects can be increased when Prazosin is combined with Desflurane. | Approved |
| Pregabalin | The risk or severity of adverse effects can be increased when Pregabalin is combined with Desflurane. | Approved, Illicit, Investigational |
| Prilocaine | The risk or severity of adverse effects can be increased when Prilocaine is combined with Desflurane. | Approved |
| Primaquine | Desflurane may increase the QTc-prolonging activities of Primaquine. | Approved |
| Primidone | The risk or severity of adverse effects can be increased when Desflurane is combined with Primidone. | Approved, Vet Approved |
| Procainamide | Desflurane may increase the QTc-prolonging activities of Procainamide. | Approved |
| Procaine | The risk or severity of adverse effects can be increased when Procaine is combined with Desflurane. | Approved, Investigational, Vet Approved |
| Prochlorperazine | The risk or severity of adverse effects can be increased when Prochlorperazine is combined with Desflurane. | Approved, Vet Approved |
| Promazine | Desflurane may increase the QTc-prolonging activities of Promazine. | Approved, Vet Approved |
| Promethazine | The risk or severity of adverse effects can be increased when Desflurane is combined with Promethazine. | Approved |
| Propafenone | Desflurane may increase the QTc-prolonging activities of Propafenone. | Approved |
| Proparacaine | The risk or severity of adverse effects can be increased when Proparacaine is combined with Desflurane. | Approved, Vet Approved |
| Propofol | The risk or severity of adverse effects can be increased when Propofol is combined with Desflurane. | Approved, Investigational, Vet Approved |
| Propoxycaine | The risk or severity of adverse effects can be increased when Desflurane is combined with Propoxycaine. | Approved |
| Propranolol | The risk or severity of adverse effects can be increased when Propranolol is combined with Desflurane. | Approved, Investigational |
| Protriptyline | The risk or severity of adverse effects can be increased when Desflurane is combined with Protriptyline. | Approved |
| Quazepam | The risk or severity of adverse effects can be increased when Desflurane is combined with Quazepam. | Approved, Illicit |
| Quetiapine | Desflurane may increase the QTc-prolonging activities of Quetiapine. | Approved |
| Quinapril | The risk or severity of adverse effects can be increased when Quinapril is combined with Desflurane. | Approved, Investigational |
| Quinidine | Desflurane may increase the QTc-prolonging activities of Quinidine. | Approved |
| Quinine | Desflurane may increase the QTc-prolonging activities of Quinine. | Approved |
| Raclopride | The risk or severity of adverse effects can be increased when Desflurane is combined with Raclopride. | Investigational |
| Ramelteon | The risk or severity of adverse effects can be increased when Desflurane is combined with Ramelteon. | Approved, Investigational |
| Ramipril | The risk or severity of adverse effects can be increased when Ramipril is combined with Desflurane. | Approved |
| Rapacuronium | Desflurane may increase the neuromuscular blocking activities of Rapacuronium. | Withdrawn |
| Rasagiline | The risk or severity of adverse effects can be increased when Desflurane is combined with Rasagiline. | Approved |
| Remifentanil | The risk or severity of adverse effects can be increased when Remifentanil is combined with Desflurane. | Approved |
| Remoxipride | The risk or severity of adverse effects can be increased when Remoxipride is combined with Desflurane. | Approved, Withdrawn |
| Reserpine | The risk or severity of adverse effects can be increased when Reserpine is combined with Desflurane. | Approved |
| Riociguat | The risk or severity of adverse effects can be increased when Riociguat is combined with Desflurane. | Approved |
| Risperidone | Desflurane may increase the hypotensive activities of Risperidone. | Approved, Investigational |
| Ritanserin | The risk or severity of adverse effects can be increased when Desflurane is combined with Ritanserin. | Investigational |
| Ropinirole | Desflurane may increase the sedative activities of Ropinirole. | Approved, Investigational |
| Ropivacaine | The risk or severity of adverse effects can be increased when Ropivacaine is combined with Desflurane. | Approved |
| Rotigotine | Desflurane may increase the sedative activities of Rotigotine. | Approved |
| Rufinamide | The risk or severity of adverse effects can be increased when Rufinamide is combined with Desflurane. | Approved |
| Sacubitril | The risk or severity of adverse effects can be increased when Desflurane is combined with Sacubitril. | Approved |
| Saquinavir | Desflurane may increase the QTc-prolonging activities of Saquinavir. | Approved, Investigational |
| Scopolamine | The risk or severity of adverse effects can be increased when Desflurane is combined with Scopolamine. | Approved |
| Secobarbital | The risk or severity of adverse effects can be increased when Secobarbital is combined with Desflurane. | Approved, Vet Approved |
| Selegiline | The risk or severity of adverse effects can be increased when Desflurane is combined with Selegiline. | Approved, Investigational, Vet Approved |
| Sepranolone | The risk or severity of adverse effects can be increased when Desflurane is combined with Uc1010. | Investigational |
| Sertindole | The risk or severity of adverse effects can be increased when Desflurane is combined with Sertindole. | Approved, Withdrawn |
| Sertraline | The risk or severity of adverse effects can be increased when Desflurane is combined with Sertraline. | Approved |
| Sevoflurane | The risk or severity of adverse effects can be increased when Desflurane is combined with Sevoflurane. | Approved, Vet Approved |
| Sodium Nitrite | The risk or severity of adverse effects can be increased when Desflurane is combined with Sodium Nitrite. | Approved |
| Sodium oxybate | Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Desflurane. | Approved |
| Sotalol | Desflurane may increase the QTc-prolonging activities of Sotalol. | Approved |
| Spironolactone | The risk or severity of adverse effects can be increased when Spironolactone is combined with Desflurane. | Approved |
| Stiripentol | The risk or severity of adverse effects can be increased when Desflurane is combined with Stiripentol. | Approved |
| Streptokinase | The risk or severity of adverse effects can be increased when Desflurane is combined with Streptokinase. | Approved |
| Sufentanil | The risk or severity of adverse effects can be increased when Sufentanil is combined with Desflurane. | Approved, Investigational |
| Sulfisoxazole | Desflurane may increase the QTc-prolonging activities of Sulfisoxazole. | Approved, Vet Approved |
| Sulpiride | The risk or severity of adverse effects can be increased when Sulpiride is combined with Desflurane. | Approved |
| Suvorexant | Desflurane may increase the central nervous system depressant (CNS depressant) activities of Suvorexant. | Approved |
| Tamsulosin | The risk or severity of adverse effects can be increased when Desflurane is combined with Tamsulosin. | Approved, Investigational |
| Tandospirone | The risk or severity of adverse effects can be increased when Desflurane is combined with Tandospirone. | Investigational |
| Tapentadol | Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Desflurane. | Approved |
| Tasimelteon | The risk or severity of adverse effects can be increased when Desflurane is combined with Tasimelteon. | Approved |
| Telavancin | Desflurane may increase the QTc-prolonging activities of Telavancin. | Approved |
| Telithromycin | Desflurane may increase the QTc-prolonging activities of Telithromycin. | Approved |
| Telmisartan | The risk or severity of adverse effects can be increased when Telmisartan is combined with Desflurane. | Approved, Investigational |
| Temazepam | The risk or severity of adverse effects can be increased when Temazepam is combined with Desflurane. | Approved |
| Terazosin | The risk or severity of adverse effects can be increased when Terazosin is combined with Desflurane. | Approved |
| Tetrabenazine | Desflurane may increase the QTc-prolonging activities of Tetrabenazine. | Approved |
| Tetracaine | The risk or severity of adverse effects can be increased when Desflurane is combined with Tetracaine. | Approved, Vet Approved |
| Tetrodotoxin | The risk or severity of adverse effects can be increased when Desflurane is combined with Tetrodotoxin. | Investigational |
| Thalidomide | Desflurane may increase the central nervous system depressant (CNS depressant) activities of Thalidomide. | Approved, Investigational, Withdrawn |
| Thiamylal | The risk or severity of adverse effects can be increased when Thiamylal is combined with Desflurane. | Approved, Vet Approved |
| Thiopental | The risk or severity of adverse effects can be increased when Thiopental is combined with Desflurane. | Approved, Vet Approved |
| Thioridazine | Desflurane may increase the QTc-prolonging activities of Thioridazine. | Withdrawn |
| Thiothixene | The risk or severity of adverse effects can be increased when Desflurane is combined with Thiothixene. | Approved |
| Tiagabine | The risk or severity of adverse effects can be increased when Desflurane is combined with Tiagabine. | Approved |
| Tiapride | The risk or severity of adverse effects can be increased when Desflurane is combined with Tiapride. | Approved, Investigational |
| Timolol | The risk or severity of adverse effects can be increased when Timolol is combined with Desflurane. | Approved |
| Tizanidine | The risk or severity of adverse effects can be increased when Desflurane is combined with Tizanidine. | Approved |
| Tolazoline | The risk or severity of adverse effects can be increased when Desflurane is combined with Tolazoline. | Approved, Vet Approved |
| Tolcapone | The risk or severity of adverse effects can be increased when Desflurane is combined with Tolcapone. | Approved, Withdrawn |
| Topiramate | The risk or severity of adverse effects can be increased when Desflurane is combined with Topiramate. | Approved |
| Torasemide | The risk or severity of adverse effects can be increased when Torasemide is combined with Desflurane. | Approved |
| Toremifene | Desflurane may increase the QTc-prolonging activities of Toremifene. | Approved, Investigational |
| Tramadol | The risk or severity of adverse effects can be increased when Tramadol is combined with Desflurane. | Approved, Investigational |
| Trandolapril | The risk or severity of adverse effects can be increased when Trandolapril is combined with Desflurane. | Approved |
| Trans-2-Phenylcyclopropylamine | The risk or severity of adverse effects can be increased when Desflurane is combined with Trans-2-Phenylcyclopropylamine. | Experimental |
| Tranylcypromine | The risk or severity of adverse effects can be increased when Tranylcypromine is combined with Desflurane. | Approved |
| Trazodone | The risk or severity of adverse effects can be increased when Trazodone is combined with Desflurane. | Approved, Investigational |
| Tretinoin | The risk or severity of adverse effects can be increased when Desflurane is combined with Tretinoin. | Approved, Investigational, Nutraceutical |
| Triamterene | The risk or severity of adverse effects can be increased when Triamterene is combined with Desflurane. | Approved |
| Triazolam | The risk or severity of adverse effects can be increased when Triazolam is combined with Desflurane. | Approved |
| Trifluoperazine | The risk or severity of adverse effects can be increased when Trifluoperazine is combined with Desflurane. | Approved |
| Triflupromazine | The risk or severity of adverse effects can be increased when Triflupromazine is combined with Desflurane. | Approved, Vet Approved |
| Trimipramine | The risk or severity of adverse effects can be increased when Desflurane is combined with Trimipramine. | Approved |
| Triprolidine | The risk or severity of adverse effects can be increased when Desflurane is combined with Triprolidine. | Approved |
| Valproic Acid | The risk or severity of adverse effects can be increased when Valproic Acid is combined with Desflurane. | Approved, Investigational |
| Valsartan | The risk or severity of adverse effects can be increased when Valsartan is combined with Desflurane. | Approved, Investigational |
| Vandetanib | Desflurane may increase the QTc-prolonging activities of Vandetanib. | Approved |
| Vemurafenib | Desflurane may increase the QTc-prolonging activities of Vemurafenib. | Approved |
| Venlafaxine | The risk or severity of adverse effects can be increased when Desflurane is combined with Venlafaxine. | Approved |
| Verapamil | The risk or severity of adverse effects can be increased when Verapamil is combined with Desflurane. | Approved |
| Vigabatrin | The risk or severity of adverse effects can be increased when Desflurane is combined with Vigabatrin. | Approved |
| Vortioxetine | The risk or severity of adverse effects can be increased when Desflurane is combined with Vortioxetine. | Approved |
| Zaleplon | The risk or severity of adverse effects can be increased when Zaleplon is combined with Desflurane. | Approved, Illicit, Investigational |
| Ziconotide | The risk or severity of adverse effects can be increased when Desflurane is combined with Ziconotide. | Approved |
| Zimelidine | The risk or severity of adverse effects can be increased when Desflurane is combined with Zimelidine. | Withdrawn |
| Ziprasidone | Desflurane may increase the QTc-prolonging activities of Ziprasidone. | Approved |
| Zolpidem | Desflurane may increase the central nervous system depressant (CNS depressant) activities of Zolpidem. | Approved |
| Zonisamide | The risk or severity of adverse effects can be increased when Desflurane is combined with Zonisamide. | Approved, Investigational |
| Zopiclone | The risk or severity of adverse effects can be increased when Desflurane is combined with Zopiclone. | Approved |
| Zotepine | The risk or severity of adverse effects can be increased when Desflurane is combined with Zotepine. | Approved |
| Zuclopenthixol | Desflurane may increase the QTc-prolonging activities of Zuclopenthixol. | Approved, Investigational |
