Mitoxantrone Recruiting Phase 1 / 2 Trials for High Risk Myelodysplastic Syndrome / Leukemia Acute Myeloid Leukemia (AML) / Myeloproliferative Neoplasms / Myelodysplastic Syndrome / Acute Biphenotypic Leukemia (ABL) / de Novo Myelodysplastic Syndrome Treatment