Showing BioInteractions for Decitabine (DB01262)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Decitabine is a DNA (cytosine-5)-methyltransferase 1 inhibitor | ||
| 1 | DNA (cytosine-5)-methyltransferase 1 inhibitors | Azacitidine, Epigallocatechin gallate, Procaine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Decitabine is a DNA (cytosine-5)-methyltransferase 3A inhibitor | ||
| 1 | DNA (cytosine-5)-methyltransferase 3A inhibitors | Procaine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Decitabine is a DNA (cytosine-5)-methyltransferase 3B inhibitor | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Decitabine is a Deoxycytidine kinase substrate | ||
| 1 | Deoxycytidine kinase substrates | 2'-Deoxycytidine, Cladribine, Clofarabine, Cytarabine, Emtricitabine, Gemcitabine, Lamivudine, Nelarabine, Zalcitabine |
| 2 | Deoxycytidine kinase inducers | Pemetrexed |
| 3 | Deoxycytidine kinase agonists | Fludarabine |
| 4 | Deoxycytidine kinase activators | Troxacitabine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Decitabine is a UMP-CMP kinase substrate | ||
| 1 | UMP-CMP kinase inhibitors | Gemcitabine |
| 2 | UMP-CMP kinase substrates | Lamivudine, Sofosbuvir |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Decitabine is a Nucleoside diphosphokinase substrate | ||
| 1 | Nucleoside diphosphokinase substrates | Acyclovir, Tenofovir disoproxil |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Decitabine is a Cytidine deaminase substrate | ||
| 1 | Cytidine deaminase substrates | Azacitidine, Capecitabine, Cytarabine, Gemcitabine |
| 2 | Cytidine deaminase ligands | 1-Beta-Ribofuranosyl-1,3-Diazepinone |
| 3 | Cytidine deaminase inhibitors | Cedazuridine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Decitabine is a Sodium/nucleoside cotransporter 1 substrate | ||
| 1 | Sodium/nucleoside cotransporter 1 substrates | Adenosine, Tegafur-uracil, Trifluridine |