Showing BioInteractions for Nelarabine (DB01280)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Nelarabine is a DNA polymerase alpha catalytic subunit inhibitor | ||
| 1 | DNA polymerase alpha catalytic subunit inhibitors | Cladribine, Clofarabine, Fludarabine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Nelarabine is a Adenosine deaminase substrate | ||
| 1 | Adenosine deaminase inhibitors | Dipyridamole, Edetate calcium disodium anhydrous, Edetate disodium anhydrous, Edetic acid, Erdosteine, Pentostatin, Theophylline |
| 2 | Adenosine deaminase substrates | Adenosine, Vidarabine |
| 3 | Adenosine deaminase inducers | Theophylline |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Nelarabine is a Deoxycytidine kinase substrate | ||
| 1 | Deoxycytidine kinase substrates | 2'-Deoxycytidine, Cladribine, Clofarabine, Cytarabine, Decitabine, Emtricitabine, Gemcitabine, Lamivudine, Zalcitabine |
| 2 | Deoxycytidine kinase inducers | Pemetrexed |
| 3 | Deoxycytidine kinase agonists | Fludarabine |
| 4 | Deoxycytidine kinase activators | Troxacitabine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Nelarabine is a Deoxyguanosine kinase, mitochondrial substrate | ||