Identification

Name
Ginseng
Accession Number
DB01404
Type
Small Molecule
Groups
Approved, Investigational, Nutraceutical
Description

Ginseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties. Ginseng is also known to contain phytoestrogens.

Synonyms
  • Aralia ginseng root
  • Asian ginseng root
  • Chinese ginseng root
  • Ginseng (panax ginseng)
  • Ginseng extract
  • Ginseng, asian
  • Hong shen root
  • Insam root
  • Korean ginseng
  • Korean ginseng root
  • Ninjin root
  • Panax ginseng
  • Panax ginseng root
  • Panax ginseng root extract
  • Panax schinseng root
  • Panax verus root
  • Red ginseng
  • Ren seng root
  • Ren shen
  • Ren shen root
  • True ginseng root
External IDs
B1673
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Siberian Ginseng ExtractumLiquid1300 mgOralClassical Remedia LtdNot applicableNot applicableCanada
Siberian Ginseng TabletTablet3000 mgOralClassical Remedia LtdNot applicableNot applicableCanada
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Ginsana Cap 100mgCapsule100 mgOralQuest Vitamins A Div Of Purity Life Health Products1995-12-312006-07-25Canada
Ginseng Energy Formula TabletsTablet100 mgOralAshbury Research CorporationNot applicableNot applicableCanada
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Baek Su Hee (joy 99 year life) (20ml)Ginseng (.5 g/20mL)LiquidOralMercylight2015-06-26Not applicableUs
Cheong-Kwan-Jang Korean HongSamGinseng (500 mg/500mg)CapsuleOralKorea Ginseng Corporation2010-11-15Not applicableUs
Cheong-Kwan-Jang Korean HongSamGinseng (90 g/90g)PowderOralKorea Ginseng Corporation2010-10-08Not applicableUs
Cheong-Kwan-Jang Korean HongSamGinseng (500 mg/90000mg)TabletOralKorea Ginseng Corporation2011-02-24Not applicableUs
Cheong-Kwan-Jang Sliced Korean HongSamGinseng (75 g/75g)Bar, chewableOralKorea Ginseng Corporation2011-05-31Not applicableUs
GimGinseng (24 g/100mL)LiquidTopicalHalim Pharm Ltd2014-02-08Not applicableUs
Liver Care Honzo Seika Chinese Herbal Aroma OilGinseng (46 mg/100mL)OilTopicalNic Co., Ltd.2016-04-01Not applicableUs
Liver Care Honzo Seika Chinese Herbal Aroma OilGinseng (46 mg/100mL)OilTopicalPhytopia Co., Ltd.2016-04-01Not applicableUs
Qelby Healing FoodGinseng (.05 g/1)CapsuleOralQuantum Energy Co., Ltd.2014-12-22Not applicableUs
SingisoGinseng (.125 g/.8g)TabletOralSae in Dang Co., Ltd.2015-04-01Not applicableUs
Categories
UNII
Not Available
CAS number
50647-08-0
Weight
Not Available
Chemical Formula
Not Available
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
TargetActionsOrganism
UInterleukin-6
antagonist
Human
UProstaglandin G/H synthase 2
inhibitor
Human
UAryl hydrocarbon receptor
agonist
Human
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
(4R)-limoneneThe risk or severity of adverse effects can be increased when (4R)-limonene is combined with Ginseng.Investigational
16-BromoepiandrosteroneThe risk or severity of adverse effects can be increased when 16-Bromoepiandrosterone is combined with Ginseng.Investigational
19-norandrostenedioneThe risk or severity of adverse effects can be increased when 19-norandrostenedione is combined with Ginseng.Experimental, Illicit
5-androstenedioneThe risk or severity of adverse effects can be increased when 5-androstenedione is combined with Ginseng.Experimental, Illicit
AceclofenacThe risk or severity of adverse effects can be increased when Aceclofenac is combined with Ginseng.Approved, Investigational
AcemetacinThe risk or severity of adverse effects can be increased when Acemetacin is combined with Ginseng.Approved, Experimental, Investigational
AcenocoumarolGinseng may increase the anticoagulant activities of Acenocoumarol.Approved, Investigational
AdapaleneThe risk or severity of adverse effects can be increased when Adapalene is combined with Ginseng.Approved
AlaproclateAlaproclate may increase the antiplatelet activities of Ginseng.Experimental
AlclofenacThe risk or severity of adverse effects can be increased when Alclofenac is combined with Ginseng.Approved, Withdrawn
AlclometasoneThe risk or severity of adverse effects can be increased when Alclometasone is combined with Ginseng.Approved
AldosteroneThe risk or severity of adverse effects can be increased when Aldosterone is combined with Ginseng.Experimental, Investigational
AlminoprofenThe risk or severity of adverse effects can be increased when Alminoprofen is combined with Ginseng.Experimental
AmcinonideThe risk or severity of adverse effects can be increased when Amcinonide is combined with Ginseng.Approved
AndrographolideThe risk or severity of adverse effects can be increased when Andrographolide is combined with Ginseng.Investigational
AndrostenedioneThe risk or severity of adverse effects can be increased when Androstenedione is combined with Ginseng.Experimental, Illicit
AnecortaveThe risk or severity of adverse effects can be increased when Anecortave is combined with Ginseng.Investigational
anecortave acetateThe risk or severity of adverse effects can be increased when anecortave acetate is combined with Ginseng.Investigational
AnisodamineThe risk or severity of adverse effects can be increased when Anisodamine is combined with Ginseng.Investigational
AntipyrineThe risk or severity of adverse effects can be increased when Antipyrine is combined with Ginseng.Approved, Investigational
ApocyninThe risk or severity of adverse effects can be increased when Apocynin is combined with Ginseng.Investigational
ApremilastThe risk or severity of adverse effects can be increased when Apremilast is combined with Ginseng.Approved, Investigational
AtamestaneThe risk or severity of adverse effects can be increased when Atamestane is combined with Ginseng.Investigational
AzapropazoneThe risk or severity of adverse effects can be increased when Azapropazone is combined with Ginseng.Withdrawn
AzelastineThe risk or severity of adverse effects can be increased when Azelastine is combined with Ginseng.Approved
BalsalazideThe risk or severity of adverse effects can be increased when Balsalazide is combined with Ginseng.Approved, Investigational
BazedoxifeneGinseng may increase the thrombogenic activities of Bazedoxifene.Approved, Investigational
BendazacThe risk or severity of adverse effects can be increased when Bendazac is combined with Ginseng.Experimental
BenorilateThe risk or severity of adverse effects can be increased when Benorilate is combined with Ginseng.Experimental
BenoxaprofenThe risk or severity of adverse effects can be increased when Benoxaprofen is combined with Ginseng.Withdrawn
BenzydamineThe risk or severity of adverse effects can be increased when Benzydamine is combined with Ginseng.Approved
BetamethasoneThe risk or severity of adverse effects can be increased when Betamethasone is combined with Ginseng.Approved, Vet Approved
BevoniumThe risk or severity of adverse effects can be increased when Bevonium is combined with Ginseng.Experimental
BromfenacThe risk or severity of adverse effects can be increased when Bromfenac is combined with Ginseng.Approved
BucillamineThe risk or severity of adverse effects can be increased when Bucillamine is combined with Ginseng.Investigational
BufexamacThe risk or severity of adverse effects can be increased when Bufexamac is combined with Ginseng.Approved, Experimental
BumadizoneThe risk or severity of adverse effects can be increased when Bumadizone is combined with Ginseng.Experimental
Carbaspirin calciumThe risk or severity of adverse effects can be increased when Carbaspirin calcium is combined with Ginseng.Experimental, Investigational
CarprofenThe risk or severity of adverse effects can be increased when Carprofen is combined with Ginseng.Approved, Vet Approved, Withdrawn
CastanospermineThe risk or severity of adverse effects can be increased when Castanospermine is combined with Ginseng.Experimental
CelecoxibThe risk or severity of adverse effects can be increased when Celecoxib is combined with Ginseng.Approved, Investigational
ChloroquineThe risk or severity of adverse effects can be increased when Chloroquine is combined with Ginseng.Approved, Investigational, Vet Approved
ChlorotrianiseneGinseng may increase the thrombogenic activities of Chlorotrianisene.Investigational, Withdrawn
Choline magnesium trisalicylateThe risk or severity of adverse effects can be increased when Choline magnesium trisalicylate is combined with Ginseng.Approved
CiclesonideThe risk or severity of adverse effects can be increased when Ciclesonide is combined with Ginseng.Approved, Investigational
CitalopramCitalopram may increase the antiplatelet activities of Ginseng.Approved
ClobetasolThe risk or severity of adverse effects can be increased when Clobetasol is combined with Ginseng.Approved, Investigational
Clobetasol propionateThe risk or severity of adverse effects can be increased when Clobetasol propionate is combined with Ginseng.Approved
ClobetasoneThe risk or severity of adverse effects can be increased when Clobetasone is combined with Ginseng.Approved
ClocortoloneThe risk or severity of adverse effects can be increased when Clocortolone is combined with Ginseng.Approved
ClonixinThe risk or severity of adverse effects can be increased when Clonixin is combined with Ginseng.Approved
ClorindioneGinseng may increase the anticoagulant activities of Clorindione.Experimental
Conjugated estrogensGinseng may increase the thrombogenic activities of Conjugated estrogens.Approved
Cortexolone 17α-propionateThe risk or severity of adverse effects can be increased when Cortexolone 17α-propionate is combined with Ginseng.Investigational
CorticosteroneThe risk or severity of adverse effects can be increased when Corticosterone is combined with Ginseng.Experimental
Cortisone acetateThe risk or severity of adverse effects can be increased when Cortisone acetate is combined with Ginseng.Approved, Investigational
CurcuminThe risk or severity of adverse effects can be increased when Curcumin is combined with Ginseng.Approved, Investigational
DaidzeinGinseng may increase the thrombogenic activities of Daidzein.Experimental
DapoxetineDapoxetine may increase the antiplatelet activities of Ginseng.Investigational
DeflazacortThe risk or severity of adverse effects can be increased when Deflazacort is combined with Ginseng.Approved, Investigational
DesonideThe risk or severity of adverse effects can be increased when Desonide is combined with Ginseng.Approved, Investigational
DesoximetasoneThe risk or severity of adverse effects can be increased when Desoximetasone is combined with Ginseng.Approved
Desoxycorticosterone acetateThe risk or severity of adverse effects can be increased when Desoxycorticosterone acetate is combined with Ginseng.Approved
Desoxycorticosterone PivalateThe risk or severity of adverse effects can be increased when Desoxycorticosterone Pivalate is combined with Ginseng.Experimental, Vet Approved
Dexamethasone isonicotinateThe risk or severity of adverse effects can be increased when Dexamethasone isonicotinate is combined with Ginseng.Vet Approved
DicoumarolGinseng may increase the anticoagulant activities of Dicoumarol.Approved
DienestrolGinseng may increase the thrombogenic activities of Dienestrol.Approved, Investigational
DiethylstilbestrolGinseng may increase the thrombogenic activities of Diethylstilbestrol.Approved, Investigational
DifenpiramideThe risk or severity of adverse effects can be increased when Difenpiramide is combined with Ginseng.Experimental
DiflorasoneThe risk or severity of adverse effects can be increased when Diflorasone is combined with Ginseng.Approved
DiflunisalThe risk or severity of adverse effects can be increased when Diflunisal is combined with Ginseng.Approved, Investigational
DifluocortoloneThe risk or severity of adverse effects can be increased when Difluocortolone is combined with Ginseng.Approved, Investigational, Withdrawn
DifluprednateThe risk or severity of adverse effects can be increased when Difluprednate is combined with Ginseng.Approved
DiphenadioneGinseng may increase the anticoagulant activities of Diphenadione.Experimental
DroxicamThe risk or severity of adverse effects can be increased when Droxicam is combined with Ginseng.Withdrawn
DuloxetineDuloxetine may increase the antiplatelet activities of Ginseng.Approved
DuvelisibThe risk or severity of adverse effects can be increased when Duvelisib is combined with Ginseng.Investigational
E-6201The risk or severity of adverse effects can be increased when E-6201 is combined with Ginseng.Investigational
EpimestrolGinseng may increase the thrombogenic activities of Epimestrol.Experimental
EpirizoleThe risk or severity of adverse effects can be increased when Epirizole is combined with Ginseng.Approved
EquileninThe risk or severity of adverse effects can be increased when Equilenin is combined with Ginseng.Experimental
EquilinThe risk or severity of adverse effects can be increased when Equilin is combined with Ginseng.Approved
EquolGinseng may increase the thrombogenic activities of Equol.Investigational
EscitalopramEscitalopram may increase the antiplatelet activities of Ginseng.Approved, Investigational
Estradiol acetateGinseng may increase the thrombogenic activities of Estradiol acetate.Approved, Investigational, Vet Approved
Estradiol cypionateGinseng may increase the thrombogenic activities of Estradiol cypionate.Approved, Investigational, Vet Approved
Estradiol valerateGinseng may increase the thrombogenic activities of Estradiol valerate.Approved, Investigational, Vet Approved
EstriolGinseng may increase the thrombogenic activities of Estriol.Approved, Investigational, Vet Approved
Estrogens, esterifiedGinseng may increase the thrombogenic activities of Estrogens, esterified.Approved
EstroneGinseng may increase the thrombogenic activities of Estrone.Approved
Estrone sulfateThe risk or severity of adverse effects can be increased when Estrone sulfate is combined with Ginseng.Approved
EtanerceptThe risk or severity of adverse effects can be increased when Etanercept is combined with Ginseng.Approved, Investigational
EthenzamideThe risk or severity of adverse effects can be increased when Ethenzamide is combined with Ginseng.Experimental
Ethyl biscoumacetateGinseng may increase the anticoagulant activities of Ethyl biscoumacetate.Withdrawn
EtodolacThe risk or severity of adverse effects can be increased when Etodolac is combined with Ginseng.Approved, Investigational, Vet Approved
EtofenamateThe risk or severity of adverse effects can be increased when Etofenamate is combined with Ginseng.Approved, Investigational
EtoperidoneEtoperidone may increase the antiplatelet activities of Ginseng.Withdrawn
EtoricoxibThe risk or severity of adverse effects can be increased when Etoricoxib is combined with Ginseng.Approved, Investigational
Evening primrose oilThe risk or severity of adverse effects can be increased when Evening primrose oil is combined with Ginseng.Investigational, Nutraceutical
ExisulindThe risk or severity of adverse effects can be increased when Exisulind is combined with Ginseng.Investigational
FelbinacThe risk or severity of adverse effects can be increased when Felbinac is combined with Ginseng.Experimental
FenbufenThe risk or severity of adverse effects can be increased when Fenbufen is combined with Ginseng.Approved
FenoprofenThe risk or severity of adverse effects can be increased when Fenoprofen is combined with Ginseng.Approved
FentiazacThe risk or severity of adverse effects can be increased when Fentiazac is combined with Ginseng.Experimental
FeprazoneThe risk or severity of adverse effects can be increased when Feprazone is combined with Ginseng.Experimental
Ferulic acidThe risk or severity of adverse effects can be increased when Ferulic acid is combined with Ginseng.Experimental
FloctafenineThe risk or severity of adverse effects can be increased when Floctafenine is combined with Ginseng.Approved, Withdrawn
FluasteroneThe risk or severity of adverse effects can be increased when Fluasterone is combined with Ginseng.Investigational
FludrocortisoneThe risk or severity of adverse effects can be increased when Fludrocortisone is combined with Ginseng.Approved, Investigational
FluindioneGinseng may increase the anticoagulant activities of Fluindione.Approved, Investigational
FlumethasoneThe risk or severity of adverse effects can be increased when Flumethasone is combined with Ginseng.Approved, Vet Approved
FlunisolideThe risk or severity of adverse effects can be increased when Flunisolide is combined with Ginseng.Approved, Investigational
FlunixinThe risk or severity of adverse effects can be increased when Flunixin is combined with Ginseng.Vet Approved
FlunoxaprofenThe risk or severity of adverse effects can be increased when Flunoxaprofen is combined with Ginseng.Experimental
Fluocinolone AcetonideThe risk or severity of adverse effects can be increased when Fluocinolone Acetonide is combined with Ginseng.Approved, Investigational, Vet Approved
FluocinonideThe risk or severity of adverse effects can be increased when Fluocinonide is combined with Ginseng.Approved, Investigational
FluocortoloneThe risk or severity of adverse effects can be increased when Fluocortolone is combined with Ginseng.Approved, Withdrawn
FluorometholoneThe risk or severity of adverse effects can be increased when Fluorometholone is combined with Ginseng.Approved, Investigational
FluprednideneThe risk or severity of adverse effects can be increased when Fluprednidene is combined with Ginseng.Approved, Withdrawn
FluprednisoloneThe risk or severity of adverse effects can be increased when Fluprednisolone is combined with Ginseng.Approved
FlurandrenolideThe risk or severity of adverse effects can be increased when Flurandrenolide is combined with Ginseng.Approved
FlurbiprofenThe risk or severity of adverse effects can be increased when Flurbiprofen is combined with Ginseng.Approved, Investigational
FluticasoneThe risk or severity of adverse effects can be increased when Fluticasone is combined with Ginseng.Approved, Experimental, Investigational
Fluticasone furoateThe risk or severity of adverse effects can be increased when Fluticasone furoate is combined with Ginseng.Approved
FormestaneThe risk or severity of adverse effects can be increased when Formestane is combined with Ginseng.Approved, Investigational, Withdrawn
GenisteinGinseng may increase the thrombogenic activities of Genistein.Investigational
GuacetisalThe risk or severity of adverse effects can be increased when Guacetisal is combined with Ginseng.Experimental
HalcinonideThe risk or severity of adverse effects can be increased when Halcinonide is combined with Ginseng.Approved, Investigational, Withdrawn
HE3286The risk or severity of adverse effects can be increased when HE3286 is combined with Ginseng.Investigational
HexestrolGinseng may increase the thrombogenic activities of Hexestrol.Withdrawn
HigenamineThe risk or severity of adverse effects can be increased when Higenamine is combined with Ginseng.Investigational
IbuproxamThe risk or severity of adverse effects can be increased when Ibuproxam is combined with Ginseng.Withdrawn
IcatibantThe risk or severity of adverse effects can be increased when Icatibant is combined with Ginseng.Approved, Investigational
Imidazole salicylateThe risk or severity of adverse effects can be increased when Imidazole salicylate is combined with Ginseng.Experimental
IndalpineIndalpine may increase the antiplatelet activities of Ginseng.Investigational, Withdrawn
IndobufenThe risk or severity of adverse effects can be increased when Indobufen is combined with Ginseng.Investigational
IndomethacinThe risk or severity of adverse effects can be increased when Indomethacin is combined with Ginseng.Approved, Investigational
IndoprofenThe risk or severity of adverse effects can be increased when Indoprofen is combined with Ginseng.Withdrawn
IsoxicamThe risk or severity of adverse effects can be increased when Isoxicam is combined with Ginseng.Withdrawn
IstaroximeThe risk or severity of adverse effects can be increased when Istaroxime is combined with Ginseng.Investigational
KebuzoneThe risk or severity of adverse effects can be increased when Kebuzone is combined with Ginseng.Experimental
KetoprofenThe risk or severity of adverse effects can be increased when Ketoprofen is combined with Ginseng.Approved, Vet Approved
LeflunomideThe risk or severity of adverse effects can be increased when Leflunomide is combined with Ginseng.Approved, Investigational
LevomilnacipranLevomilnacipran may increase the antiplatelet activities of Ginseng.Approved, Investigational
LisofyllineThe risk or severity of adverse effects can be increased when Lisofylline is combined with Ginseng.Investigational
LonazolacThe risk or severity of adverse effects can be increased when Lonazolac is combined with Ginseng.Experimental
LornoxicamThe risk or severity of adverse effects can be increased when Lornoxicam is combined with Ginseng.Approved, Investigational
LoteprednolThe risk or severity of adverse effects can be increased when Loteprednol is combined with Ginseng.Approved
LoxoprofenThe risk or severity of adverse effects can be increased when Loxoprofen is combined with Ginseng.Approved, Investigational
LumiracoxibThe risk or severity of adverse effects can be increased when Lumiracoxib is combined with Ginseng.Approved, Investigational
Magnesium salicylateThe risk or severity of adverse effects can be increased when Magnesium salicylate is combined with Ginseng.Approved
MasoprocolThe risk or severity of adverse effects can be increased when Masoprocol is combined with Ginseng.Approved, Investigational
ME-609The risk or severity of adverse effects can be increased when ME-609 is combined with Ginseng.Investigational
Meclofenamic acidThe risk or severity of adverse effects can be increased when Meclofenamic acid is combined with Ginseng.Approved, Vet Approved
MedrysoneThe risk or severity of adverse effects can be increased when Medrysone is combined with Ginseng.Approved
Mefenamic acidThe risk or severity of adverse effects can be increased when Mefenamic acid is combined with Ginseng.Approved
MelengestrolThe risk or severity of adverse effects can be increased when Melengestrol is combined with Ginseng.Vet Approved
MeloxicamThe risk or severity of adverse effects can be increased when Meloxicam is combined with Ginseng.Approved, Vet Approved
MesalazineThe risk or severity of adverse effects can be increased when Mesalazine is combined with Ginseng.Approved
MestranolGinseng may increase the thrombogenic activities of Mestranol.Approved
MetamizoleThe risk or severity of adverse effects can be increased when Metamizole is combined with Ginseng.Approved, Investigational, Withdrawn
MethallenestrilGinseng may increase the thrombogenic activities of Methallenestril.Experimental
MilnacipranMilnacipran may increase the antiplatelet activities of Ginseng.Approved, Investigational
MizoribineThe risk or severity of adverse effects can be increased when Mizoribine is combined with Ginseng.Investigational
MofebutazoneThe risk or severity of adverse effects can be increased when Mofebutazone is combined with Ginseng.Experimental
MometasoneThe risk or severity of adverse effects can be increased when Mometasone is combined with Ginseng.Approved, Vet Approved
MoxestrolGinseng may increase the thrombogenic activities of Moxestrol.Experimental
Mycophenolate mofetilThe risk or severity of adverse effects can be increased when Mycophenolate mofetil is combined with Ginseng.Approved, Investigational
Mycophenolic acidThe risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Ginseng.Approved
NabumetoneThe risk or severity of adverse effects can be increased when Nabumetone is combined with Ginseng.Approved
NafamostatThe risk or severity of adverse effects can be increased when Nafamostat is combined with Ginseng.Approved, Investigational
NaftifineThe risk or severity of adverse effects can be increased when Naftifine is combined with Ginseng.Approved
NCX 1022The risk or severity of adverse effects can be increased when NCX 1022 is combined with Ginseng.Investigational
NefazodoneNefazodone may increase the antiplatelet activities of Ginseng.Approved, Withdrawn
NepafenacThe risk or severity of adverse effects can be increased when Nepafenac is combined with Ginseng.Approved, Investigational
NifenazoneThe risk or severity of adverse effects can be increased when Nifenazone is combined with Ginseng.Experimental
Niflumic AcidThe risk or severity of adverse effects can be increased when Niflumic Acid is combined with Ginseng.Approved
NitroaspirinThe risk or severity of adverse effects can be increased when Nitroaspirin is combined with Ginseng.Investigational
Oleoyl-estroneThe risk or severity of adverse effects can be increased when Oleoyl-estrone is combined with Ginseng.Investigational
OlopatadineThe risk or severity of adverse effects can be increased when Olopatadine is combined with Ginseng.Approved
OlsalazineThe risk or severity of adverse effects can be increased when Olsalazine is combined with Ginseng.Approved
OrgoteinThe risk or severity of adverse effects can be increased when Orgotein is combined with Ginseng.Vet Approved
OxaprozinThe risk or severity of adverse effects can be increased when Oxaprozin is combined with Ginseng.Approved
OxyphenbutazoneThe risk or severity of adverse effects can be increased when Oxyphenbutazone is combined with Ginseng.Approved, Withdrawn
PalmidrolThe risk or severity of adverse effects can be increased when Palmidrol is combined with Ginseng.Experimental, Nutraceutical
ParamethasoneThe risk or severity of adverse effects can be increased when Paramethasone is combined with Ginseng.Approved
ParecoxibThe risk or severity of adverse effects can be increased when Parecoxib is combined with Ginseng.Approved
ParthenolideThe risk or severity of adverse effects can be increased when Parthenolide is combined with Ginseng.Approved, Investigational
PhenindioneGinseng may increase the anticoagulant activities of Phenindione.Approved, Investigational
PhenprocoumonGinseng may increase the anticoagulant activities of Phenprocoumon.Approved, Investigational
PhenylbutazoneThe risk or severity of adverse effects can be increased when Phenylbutazone is combined with Ginseng.Approved, Vet Approved
PimecrolimusThe risk or severity of adverse effects can be increased when Pimecrolimus is combined with Ginseng.Approved, Investigational
PirfenidoneThe risk or severity of adverse effects can be increased when Pirfenidone is combined with Ginseng.Approved, Investigational
PiroxicamThe risk or severity of adverse effects can be increased when Piroxicam is combined with Ginseng.Approved, Investigational
PirprofenThe risk or severity of adverse effects can be increased when Pirprofen is combined with Ginseng.Experimental
Polyestradiol phosphateGinseng may increase the thrombogenic activities of Polyestradiol phosphate.Approved
PranoprofenThe risk or severity of adverse effects can be increased when Pranoprofen is combined with Ginseng.Experimental, Investigational
PrasteroneThe risk or severity of adverse effects can be increased when Prasterone is combined with Ginseng.Approved, Investigational, Nutraceutical
Prasterone sulfateThe risk or severity of adverse effects can be increased when Prasterone sulfate is combined with Ginseng.Investigational
PrednicarbateThe risk or severity of adverse effects can be increased when Prednicarbate is combined with Ginseng.Approved, Investigational
PrednisoneThe risk or severity of adverse effects can be increased when Prednisone is combined with Ginseng.Approved, Vet Approved
PregnenoloneThe risk or severity of adverse effects can be increased when Pregnenolone is combined with Ginseng.Approved, Experimental, Investigational
ProglumetacinThe risk or severity of adverse effects can be increased when Proglumetacin is combined with Ginseng.Experimental
PromestrieneGinseng may increase the thrombogenic activities of Promestriene.Investigational
PropacetamolThe risk or severity of adverse effects can be increased when Propacetamol is combined with Ginseng.Approved, Investigational
PropyphenazoneThe risk or severity of adverse effects can be increased when Propyphenazone is combined with Ginseng.Experimental
ProquazoneThe risk or severity of adverse effects can be increased when Proquazone is combined with Ginseng.Experimental
PTC299The risk or severity of adverse effects can be increased when PTC299 is combined with Ginseng.Investigational
QuinestrolGinseng may increase the thrombogenic activities of Quinestrol.Approved
ResveratrolThe risk or severity of adverse effects can be increased when Resveratrol is combined with Ginseng.Approved, Experimental, Investigational
RimexoloneThe risk or severity of adverse effects can be increased when Rimexolone is combined with Ginseng.Approved
RofecoxibThe risk or severity of adverse effects can be increased when Rofecoxib is combined with Ginseng.Approved, Investigational, Withdrawn
SalicylamideThe risk or severity of adverse effects can be increased when Salicylamide is combined with Ginseng.Approved
SalsalateThe risk or severity of adverse effects can be increased when Salsalate is combined with Ginseng.Approved
SecoisolariciresinolGinseng may increase the thrombogenic activities of Secoisolariciresinol.Investigational
SemapimodThe risk or severity of adverse effects can be increased when Semapimod is combined with Ginseng.Investigational
SeratrodastThe risk or severity of adverse effects can be increased when Seratrodast is combined with Ginseng.Approved
SerrapeptaseThe risk or severity of adverse effects can be increased when Serrapeptase is combined with Ginseng.Investigational
SertralineSertraline may increase the antiplatelet activities of Ginseng.Approved
SRT501The risk or severity of adverse effects can be increased when SRT501 is combined with Ginseng.Investigational
SuprofenThe risk or severity of adverse effects can be increased when Suprofen is combined with Ginseng.Approved, Withdrawn
SuxibuzoneThe risk or severity of adverse effects can be increased when Suxibuzone is combined with Ginseng.Experimental
Synthetic Conjugated Estrogens, AGinseng may increase the thrombogenic activities of Synthetic Conjugated Estrogens, A.Approved
Synthetic Conjugated Estrogens, BGinseng may increase the thrombogenic activities of Synthetic Conjugated Estrogens, B.Approved
TarenflurbilThe risk or severity of adverse effects can be increased when Tarenflurbil is combined with Ginseng.Investigational
TenidapThe risk or severity of adverse effects can be increased when Tenidap is combined with Ginseng.Experimental
TenoxicamThe risk or severity of adverse effects can be increased when Tenoxicam is combined with Ginseng.Approved
TepoxalinThe risk or severity of adverse effects can be increased when Tepoxalin is combined with Ginseng.Vet Approved
TeriflunomideThe risk or severity of adverse effects can be increased when Teriflunomide is combined with Ginseng.Approved
Tiaprofenic acidThe risk or severity of adverse effects can be increased when Tiaprofenic acid is combined with Ginseng.Approved
TiboloneGinseng may increase the thrombogenic activities of Tibolone.Approved, Investigational
TinoridineThe risk or severity of adverse effects can be increased when Tinoridine is combined with Ginseng.Investigational
TioclomarolGinseng may increase the anticoagulant activities of Tioclomarol.Experimental
TixocortolThe risk or severity of adverse effects can be increased when Tixocortol is combined with Ginseng.Approved, Withdrawn
TolmetinThe risk or severity of adverse effects can be increased when Tolmetin is combined with Ginseng.Approved
TriamcinoloneThe risk or severity of adverse effects can be increased when Triamcinolone is combined with Ginseng.Approved, Vet Approved
TribenosideThe risk or severity of adverse effects can be increased when Tribenoside is combined with Ginseng.Experimental
TriptolideThe risk or severity of adverse effects can be increased when Triptolide is combined with Ginseng.Investigational
UlobetasolThe risk or severity of adverse effects can be increased when Ulobetasol is combined with Ginseng.Approved
ValdecoxibThe risk or severity of adverse effects can be increased when Valdecoxib is combined with Ginseng.Approved, Investigational, Withdrawn
WarfarinGinseng may increase the anticoagulant activities of Warfarin.Approved
ZaltoprofenThe risk or severity of adverse effects can be increased when Zaltoprofen is combined with Ginseng.Approved, Investigational
ZeranolGinseng may increase the thrombogenic activities of Zeranol.Vet Approved
ZileutonThe risk or severity of adverse effects can be increased when Zileuton is combined with Ginseng.Approved, Investigational, Withdrawn
ZimelidineZimelidine may increase the antiplatelet activities of Ginseng.Withdrawn
ZomepiracThe risk or severity of adverse effects can be increased when Zomepirac is combined with Ginseng.Withdrawn
Food Interactions
Not Available

References

Synthesis Reference

Iwao Hachiya, Keizo Mochizuki, Yukio Kuwada, "Method of preparing dried ginseng for drug." U.S. Patent US4446130, issued January, 1970.

US4446130
General References
  1. Lee YJ, Jin YR, Lim WC, Park WK, Cho JY, Jang S, Lee SK: Ginsenoside-Rb1 acts as a weak phytoestrogen in MCF-7 human breast cancer cells. Arch Pharm Res. 2003 Jan;26(1):58-63. [PubMed:12568360]
  2. Chan RY, Chen WF, Dong A, Guo D, Wong MS: Estrogen-like activity of ginsenoside Rg1 derived from Panax notoginseng. J Clin Endocrinol Metab. 2002 Aug;87(8):3691-5. [PubMed:12161497]
  3. Lee Y, Jin Y, Lim W, Ji S, Choi S, Jang S, Lee S: A ginsenoside-Rh1, a component of ginseng saponin, activates estrogen receptor in human breast carcinoma MCF-7 cells. J Steroid Biochem Mol Biol. 2003 Mar;84(4):463-8. [PubMed:12732291]
  4. McElhaney JE, Gravenstein S, Cole SK, Davidson E, O'neill D, Petitjean S, Rumble B, Shan JJ: A placebo-controlled trial of a proprietary extract of North American ginseng (CVT-E002) to prevent acute respiratory illness in institutionalized older adults. J Am Geriatr Soc. 2004 Jan;52(1):13-9. [PubMed:14687309]
  5. Lewis WH, Zenger VE, Lynch RG: No adaptogen response of mice to ginseng and Eleutherococcus infusions. J Ethnopharmacol. 1983 Aug;8(2):209-14. [PubMed:6685799]
External Links
PubChem Substance
46508934
PharmGKB
PA164781150
RxList
RxList Drug Page
Drugs.com
Drugs.com Drug Page
Wikipedia
Ginseng
AHFS Codes
  • 92:01.00* — Herbs and Natural Products
MSDS
Download (73.2 KB)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0CompletedBasic ScienceBlood Pressures / Cognition1
0Not Yet RecruitingSupportive CareCancer Survivors / Stage I Breast Cancer AJCC v7 / Stage I Colon Cancer AJCC v6 and v7 / Stage IA Breast Cancer AJCC v7 / Stage IB Breast Cancer AJCC v7 / Stage II Breast Cancer AJCC v6 and v7 / Stage II Colon Cancer AJCC v7 / Stage IIA Breast Cancer AJCC v6 and v7 / Stage IIA Colon Cancer AJCC v7 / Stage IIB Breast Cancer AJCC v6 and v7 / Stage IIB Colon Cancer AJCC v7 / Stage IIC Colon Cancer AJCC v7 / Stage III Breast Cancer AJCC V7 / Stage III Colon Cancer AJCC v7 / Stage IIIA Breast Cancer AJCC v7 / Stage IIIA Colon Cancer AJCC v7 / Stage IIIB Breast Cancer AJCC v7 / Stage IIIB Colon Cancer AJCC v7 / Stage IIIC Breast Cancer AJCC v7 / Stage IIIC Colon Cancer AJCC v71
1, 2CompletedTreatmentAlzheimer's Disease (AD) / Memory Decline1
1, 2CompletedTreatmentBMI >30 kg/m2 / Insulin Resistance / Schizoaffective Disorders / Schizophrenic Disorders / Tardive Dyskinesia1
2Active Not RecruitingTreatmentAdvanced Cancers / Tumors, Solid1
2Active Not RecruitingTreatmentCancer, Breast1
2CompletedTreatmentHealthy Volunteers1
2CompletedTreatmentTiredness1
3CompletedTreatmentPsychiatric Disorder NOS1
3Unknown StatusTreatmentPsychiatric Disorder NOS1
4CompletedNot AvailableHealthy Volunteers1
Not AvailableCompletedSupportive CareNeoplasms, Breast / Neoplasms, Lung1
Not AvailableCompletedTreatmentDepression / Stress1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
  • Basic Drugs Inc.
  • Contract Pharm
  • CVS Pharmacy
  • Equaline Vitamins
  • Good Neighbour Pharmacy
  • Mason Distributors
  • Mckesson Corp.
  • National Vitamin Company
  • PharmAssure
  • Pharmavite
  • Rite Aid Corp.
  • Tyler Encapsulations
Dosage forms
FormRouteStrength
CapsuleOral500 mg/500mg
PowderOral90 g/90g
TabletOral500 mg/90000mg
Bar, chewableOral75 g/75g
LiquidTopical24 g/100mL
CapsuleOral100 mg
TabletOral100 mg
OilTopical46 mg/100mL
CapsuleOral.05 g/1
LiquidOral1300 mg
TabletOral3000 mg
TabletOral.125 g/1
TabletOral.125 g/.8g
TabletOral17.19 g/100g
PowderOral5.67 g/100g
PillOral.0567 g/g
OilTopical7 mg/100mL
LiquidTopical.03 mg/mL
SolutionTopical.03 mg/mL
LiquidOral.5 g/20mL
LiquidTopical1 g/100mL
Prices
Unit descriptionCostUnit
V-r panax ginseng 300 mg capsule0.18USD capsule
Ra ginseng 100 mg softgel0.17USD softgel capsule
Eql ginseng 100 mg caplet0.15USD caplet
Eql ginseng 100 mg softgel0.15USD softgel capsule
Korean ginseng 1000 mg tablet0.14USD tablet
Siberian ginseng 250 mg capsule0.14USD capsule
CVS Pharmacy ginseng 200 mg softgel0.13USD softgel capsule
Korean ginseng 518 mg cap0.13USD capsule
Korean ginseng 350 mg capsule0.09USD capsule
Ginseng 8 gr capsule0.08USD capsule
Siberian root 1000 mg capsule0.08USD capsule
Ginseng 250 mg capsule0.07USD capsule
Ra siberian ginseng 410 mg0.05USD each
Gnp ginseng root 410 mg capsule0.04USD capsule
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Targets

Kind
Protein
Organism
Human
Pharmacological action
Unknown
Actions
Antagonist
General Function
Interleukin-6 receptor binding
Specific Function
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Inv...
Gene Name
IL6
Uniprot ID
P05231
Uniprot Name
Interleukin-6
Molecular Weight
23717.965 Da
References
  1. Kim DH, Moon YS, Lee TH, Jung JS, Suh HW, Song DK: The inhibitory effect of ginseng saponins on the stress-induced plasma interleukin-6 level in mice. Neurosci Lett. 2003 Dec 15;353(1):13-6. [PubMed:14642426]
  2. Kim SJ, Jeong HJ, Yi BJ, Kang TH, An NH, Lee EH, Yang DC, Kim HM, Hong SH, Um JY: Transgenic Panax ginseng inhibits the production of TNF-alpha, IL-6, and IL-8 as well as COX-2 expression in human mast cells. Am J Chin Med. 2007;35(2):329-39. [PubMed:17436372]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
Actions
Inhibitor
General Function
Prostaglandin-endoperoxide synthase activity
Specific Function
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and...
Gene Name
PTGS2
Uniprot ID
P35354
Uniprot Name
Prostaglandin G/H synthase 2
Molecular Weight
68995.625 Da
References
  1. Yim HW, Jong HS, Kim TY, Choi HH, Kim SG, Song SH, Kim J, Ko SG, Lee JW, Kim TY, Bang YJ: Cyclooxygenase-2 inhibits novel ginseng metabolite-mediated apoptosis. Cancer Res. 2005 Mar 1;65(5):1952-60. [PubMed:15753395]
  2. Seo JY, Lee JH, Kim NW, Her E, Chang SH, Ko NY, Yoo YH, Kim JW, Seo DW, Han JW, Kim YM, Choi WS: Effect of a fermented ginseng extract, BST204, on the expression of cyclooxygenase-2 in murine macrophages. Int Immunopharmacol. 2005 May;5(5):929-36. [PubMed:15778128]
  3. Kim SJ, Jeong HJ, Yi BJ, Kang TH, An NH, Lee EH, Yang DC, Kim HM, Hong SH, Um JY: Transgenic Panax ginseng inhibits the production of TNF-alpha, IL-6, and IL-8 as well as COX-2 expression in human mast cells. Am J Chin Med. 2007;35(2):329-39. [PubMed:17436372]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
Actions
Agonist
General Function
Transcription regulatory region dna binding
Specific Function
Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes...
Gene Name
AHR
Uniprot ID
P35869
Uniprot Name
Aryl hydrocarbon receptor
Molecular Weight
96146.705 Da
References
  1. Wang Y, Ye X, Ma Z, Liang Q, Lu B, Tan H, Xiao C, Zhang B, Gao Y: Induction of cytochrome P450 1A1 expression by ginsenoside Rg1 and Rb1 in HepG2 cells. Eur J Pharmacol. 2008 Dec 28;601(1-3):73-8. doi: 10.1016/j.ejphar.2008.10.057. Epub 2008 Nov 11. [PubMed:19022240]

Drug created on July 13, 2007 14:21 / Updated on August 15, 2018 09:51