Showing BioInteractions for Cefepime (DB01413)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefepime is a Penicillin-binding protein 2 inhibitor | ||
| 1 | Penicillin-binding protein 2 inhibitors | Amdinocillin, Cefazolin, Cefonicid, Cefoperazone, Ceftazidime, Ceftibuten, Ceftolozane, Doripenem, Ertapenem, Imipenem, Mezlocillin |
| 2 | Penicillin-binding protein 2 antagonists | Doripenem |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefepime is a Peptidoglycan synthase FtsI inhibitor | ||
| 1 | Peptidoglycan synthase FtsI inhibitors | Cefazolin, Cefmenoxime, Cefmetazole, Cefonicid, Cefoperazone, Cefoxitin, Cefpiramide, Cefpodoxime, Ceftazidime, Ceftibuten, Ertapenem |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefepime is a Penicillin-binding protein 3 inhibitor | ||
| 1 | Penicillin-binding protein 3 inhibitors | Cefiderocol, Ceftolozane, Cloxacillin, Doripenem |
| 2 | Penicillin-binding protein 3 antagonists | Doripenem |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefepime is a Penicillin-binding protein 2 inhibitor | ||
| 1 | Penicillin-binding protein 2 inhibitors | Cefiderocol, Ceftazidime |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefepime is a Solute carrier family 22 member 5 inhibitor | ||
| 1 | Solute carrier family 22 member 5 inhibitors | Acetylcholine, Aldosterone, Aminohippuric acid, Ampicillin, Arginine, Azidocillin, Benzylpenicillin, Cefadroxil, Cefalotin, Cefdinir, Cefixime, Cefradine, Ceftazidime, Cephalexin, Cephaloglycin, Choline, Choline salicylate, Cimetidine, Clonidine, Creatine, Cyclacillin, Dactinomycin, Desipramine, Diphenhydramine, Dopamine, Furosemide, Grepafloxacin, Guanidine, Histamine, Levamlodipine, Lidocaine, Lomefloxacin, Metamfetamine, Methacholine, Niacin, Nicotine, Norepinephrine, Norfloxacin, Ofloxacin, Probenecid, Procainamide, Quinidine, Quinine, Sparfloxacin, Thiamine, Valproic acid, Verapamil |
| 2 | Solute carrier family 22 member 5 substrates | Amphetamine, Formoterol, Ipratropium, Levocarnitine, Terbutaline, Tiotropium |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefepime is a Solute carrier family 15 member 1 inhibitor | ||
| 1 | Solute carrier family 15 member 1 inhibitors | Aminolevulinic acid, Amoxicillin, Ampicillin, Azidocillin, Benzylpenicillin, Captopril, Cefaclor, Cefadroxil, Cefalotin, Cefdinir, Cefixime, Cefmetazole, Cefotaxime, Cefradine, Ceftazidime, Ceftibuten, Ceftriaxone, Cefuroxime, Cephalexin, Chlorpropamide, Cloxacillin, Cyclacillin, Dicloxacillin, Enalapril, Fluvastatin, Glyburide, Levodopa, Lisinopril, Loracarbef, Methyldopa, Nateglinide, Oxacillin, Tolbutamide, Ubenimex, Valaciclovir |
| 2 | Solute carrier family 15 member 1 substrates | Benazepril, Benzylpenicillin, Cefadroxil, Cefdinir, Cefixime, Cefradine, Ceftibuten, Ceftizoxime, Cephalexin, Cilazapril, Enalapril, Fluvastatin, Fosinopril, Lisdexamfetamine, Lisinopril, Methotrexate, Moexipril, Oseltamivir, Perindopril, Quinapril, Ramipril, Spirapril, Taurine, Trandolapril, Valaciclovir |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Cefepime is a Solute carrier family 15 member 2 inhibitor | ||
| 1 | Solute carrier family 15 member 2 inhibitors | Aminolevulinic acid, Amoxicillin, Ampicillin, Azidocillin, Benzylpenicillin, Cefaclor, Cefadroxil, Cefalotin, Cefdinir, Cefixime, Cefmetazole, Cefotaxime, Cefradine, Ceftazidime, Ceftibuten, Ceftriaxone, Cefuroxime, Cephalexin, Chlorpropamide, Cloxacillin, Cyclacillin, Dicloxacillin, Glyburide, Loracarbef, Nateglinide, Oxacillin, Tolbutamide, Ubenimex, Valaciclovir |
| 2 | Solute carrier family 15 member 2 substrates | Benazepril, Cilazapril, Fosinopril, Lisinopril, Moexipril, Perindopril, Quinapril, Ramipril, Spirapril, Trandolapril, Ubenimex, Valaciclovir |