Lopinavir Completed Phase 4 Trials for Mitochondrial Toxicity / Human Immunodeficiency Virus (HIV) Infections Treatment

IndicationsStatusPurposePhase
CompletedTreatment4
clinicaltrials.gov IdentifierTitleDrugs
NCT00143689NRTI-Sparing Pilot Study
NCT01166477Clinical Trial, Open-label, Randomised, in Order to Compare the Quality of Life for Those VIH+ Patients That Start With Monotherapy on LPV/r Tablets Vs. Triple Therapy With a Boosted Protease Inhibitor
NCT00281606A Multicenter Study to Assess the Tolerability of Once Daily Lopinavir/Ritonavir (LPV/r) Liquid Versus Capsules
NCT00234975Safety of Lopinavir/Ritonavir (Kaletra) in HIV/HCV Co-infected Subjects vs Baseline Liver Biopsy Metavir Score
NCT00114933OK 2004 Study (Only Kaletra 2004 Study): Study to Evaluate Suspending Nucleosides From Triple-Drug Therapy in HIV Subjects
NCT00931463A Trial of 2 Options for Second Line Combination Antiretroviral Therapy Following Virological Failure of a Standard Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI)+2N(t)RTI First Line Regimen
NCT00752037Safety Study of Lopinavir/Ritonavir With Raltegravir in HIV-infected Patients
NCT00148759Kaletra Sex/Gender Pharmacokinetics (PK) Study
NCT00145795A Research Study to See if a Change in Therapy for HIV Infection Can Improve the Immune Response to Treatment
NCT00532168Once-daily Antiretroviral Therapy in HIV-1 Infected Patients With CD4+ Cell Counts Below 100 Cells/Mcl
NCT00700115Kaletra-isentress Treatment Evaluation
NCT00159224Induction-maintenance of Lopinavir/r in HIV-infected Subjects
NCT00335686Study on the Effect of Kaletra + Nevirapine as Maintenance Bitherapy Compared to a Triple Therapy Including Kaletra + Analogues in HIV Patients
NCT00438152Lopinavir Capsules to Kaletra or Invirase Tablets
NCT00160849Lopinavir/r Monotherapy as Maintenance Therapy After Long Term Viral Suppression
NCT00994344Clinical Study to Evaluate the Efficacy and Safety of Lopinavir/Ritonavir Monotherapy Versus Darunavir/Ritonavir Monotherapies as Simplification Switching Strategies of PI/NNRTI-Triple Therapy Based-Regimens
NCT00476359A PK and Salvage Study for Children With HIV-infection
NCT00648999Safety and Efficacy of Kaletra in ARV Therapy Experienced Patients
NCT01234116Post-Exposure Prophylaxis in Health Care Workers
NCT01116817Study to Compare the Virologic Efficacy in Cerebrospinal Fluid (CSF) and Neurocognitive State in Patients Infected by HIV-1 Long-term Treatment (> 3 Years) With Lopinavir / Ritonavir Monotherapy
NCT01513122Bone and Body Comp: A Sub Study of the SECOND-LINE Study
NCT00342355Antiretroviral Therapy for Advanced HIV Disease in South Africa
NCT00335192To Determine if There Are Pharmacokinetic Interactions at Plasma or Intracellular Level Between Nucleosides and Tenofovir
NCT01445223A Study on Antiretroviral Therapy (ART) Naïve Patients On Different Regimens to Treat Hiv (NORTHIV)
NCT01581853Pilot Simplification Study to Lopinavir/Ritonavir 800/200 mg Monotherapy Regimen Once Daily
NCT00979706Immune-based Therapy Pilot Study for the Treatment of Primary HIV Infection (PHI-IMD).