Vorinostat Completed Phase 2 Trials for Stage IV Adult Diffuse Large Cell Lymphoma / Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities / Intraocular Lymphoma / Secondary Central Nervous System Hodgkin Lymphoma / Recurrent Mantle Cell Lymphoma / Recurrent Adult Diffuse Large Cell Lymphoma / Refractory Anemia / Adult Acute Myeloid Leukemia With T(8;21)(q22;q22) / Stage III Adult Diffuse Large Cell Lymphoma / Contiguous Stage II Marginal Zone Lymphoma / Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue / Stage I Grade 2 Follicular Lymphoma / Stage IV Adult Diffuse Small Cleaved Cell Lymphoma / Stage III Adult Burkitt Lymphoma / Recurrent Grade 2 Follicular Lymphoma / Stage IV Adult Hodgkin Lymphoma / Stage IV Marginal Zone Lymphoma / Recurrent Adult Diffuse Mixed Cell Lymphoma / Stage IV Grade 1 Follicular Lymphoma / Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma / Relapsing Chronic Myelogenous Leukemia / Stage I Adult Diffuse Large Cell Lymphoma / Recurrent Marginal Zone Lymphoma / Stage III Chronic Lymphocytic Leukemia / Stage I Adult Burkitt Lymphoma / Primary Central Nervous System Hodgkin Lymphoma / Stage II Chronic Lymphocytic Leukemia / Testicular Lymphoma / Recurrent Adult Burkitt Lymphoma / Stage III Adult Lymphoblastic Lymphoma / Contiguous Stage II Grade 1 Follicular Lymphoma / Stage II Adult Hodgkin Lymphoma / Contiguous Stage II Grade 2 Follicular Lymphoma / Stage III Adult Diffuse Small Cleaved Cell Lymphoma / Small Intestine Lymphoma / Recurrent Grade 3 Follicular Lymphoma / Myelodysplastic Syndrome With Isolated Del(5q) / Refractory Anemia With Ringed Sideroblasts / Chronic Myelomonocytic Leukemia / Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma / Adult Grade III Lymphomatoid Granulomatosis / Stage I Mantle Cell Lymphoma / Stage IV Adult Diffuse Mixed Cell Lymphoma / Noncontiguous Stage II Marginal Zone Lymphoma / Recurrent Adult Hodgkin's Lymphoma / Stage III Adult Hodgkin Lymphoma / Chronic Myelogenous Leukemia, BCR-ABL1 Positive / Stage III Grade 1 Follicular Lymphoma / Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable / Secondary Central Nervous System Non-Hodgkin Lymphoma / Nodal marginal zone B-cell lymphomas / Chronic Phase Chronic Myelogenous Leukemia / Contiguous Stage II Adult Burkitt Lymphoma / Recurrent Adult Diffuse Small Cleaved Cell Lymphoma / Stage III Adult Immunoblastic Large Cell Lymphoma / Noncontiguous Stage II Adult Lymphoblastic Lymphoma / Stage I Adult Immunoblastic Large Cell Lymphoma / Noncontiguous Stage II Grade 2 Follicular Lymphoma / Stage IV Adult Lymphoblastic Lymphoma / Recurrent Adult Acute Myeloid Leukemia / Recurrent Adult Immunoblastic Large Cell Lymphoma / Stage I Grade 1 Follicular Lymphoma / Adult Acute Myeloid Leukemia in Remission / Post Transplant Lymphoproliferative Disorder / Contiguous Stage II Mantle Cell Lymphoma / Recurrent Adult Lymphoblastic Lymphoma / Recurrent Grade 1 Follicular Lymphoma / Refractory Anemia With Excess Blasts / Stage III Mantle Cell Lymphoma / Splenic Marginal Zone Lymphoma / B-Cell Chronic Lymphocytic Leukemia / Stage I Adult Hodgkin Lymphoma / Accelerated Phase Chronic Myelogenous Leukemia / Noncontiguous Stage II Grade 3 Follicular Lymphoma / Adult Acute Myeloid Leukemia With T(16;16)(p13;q22) / Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma / Stage I Chronic Lymphocytic Leukemia / Adult Acute Myeloid Leukemia With Del(5q) / Contiguous Stage II Adult Lymphoblastic Lymphoma / Contiguous Stage II Adult Diffuse Large Cell Lymphoma / Stage I Adult Diffuse Small Cleaved Cell Lymphoma / Waldenström's Macroglobulinemia (WM) / Noncontiguous Stage II Mantle Cell Lymphoma / Chronic Lymphocytic Leukemia (CLL) - Refractory / Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma / Refractory Cytopenia With Multilineage Dysplasia / Stage III Grade 3 Follicular Lymphoma / Noncontiguous Stage II Small Lymphocytic Lymphoma / Stage I Grade 3 Follicular Lymphoma / Stage I Adult Lymphoblastic Lymphoma / Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) / Stage IV Chronic Lymphocytic Leukemia / Cutaneous B-Cell Non-Hodgkin Lymphoma / Refractory Hairy Cell Leukemia / Primary Central Nervous System Non-Hodgkin Lymphoma / Stage IV Adult Burkitt Lymphoma / Stage I Adult Diffuse Mixed Cell Lymphoma / Stage IV Grade 2 Follicular Lymphoma / Recurrent Small Lymphocytic Lymphoma / Stage III Grade 2 Follicular Lymphoma / Adult Acute Myeloid Leukemia With T(15;17)(q22;q12) / Graft Versus Host Disease (GVHD) / Contiguous Stage II Small Lymphocytic Lymphoma / Contiguous Stage II Grade 3 Follicular Lymphoma / Noncontiguous Stage II Grade 1 Follicular Lymphoma / Stage III Marginal Zone Lymphoma / Stage IV Adult Immunoblastic Large Cell Lymphoma / Noncontiguous Stage II Adult Burkitt Lymphoma / Recurrent Adult Grade III Lymphomatoid Granulomatosis / Stage IV Grade 3 Follicular Lymphoma / Stage I Small Lymphocytic Lymphoma / Stage III Adult Diffuse Mixed Cell Lymphoma / Stage IV Mantle Cell Lymphoma / Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma / Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma / Stage IV Small Lymphocytic Lymphoma / Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma / Stage I Marginal Zone Lymphoma Supportive Care

IndicationsStatusPurposePhase
CompletedSupportive Care2
clinicaltrials.gov IdentifierTitleDrugs
NCT01789255Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies