Vorinostat Completed Phase 1 Trials for Stage IV Cutaneous T-Cell Non-Hodgkin Lymphoma / Stage III Adult Diffuse Mixed Cell Lymphoma / Recurrent Adult Diffuse Small Cleaved Cell Lymphoma / Stage III Small Lymphocytic Lymphoma / Stage IV Adult Hodgkin Lymphoma / Stage IV Grade 3 Follicular Lymphoma / Anaplastic Large Cell Lymphoma / Stage III Mycosis Fungoides/Sezary Syndrome / Angioimmunoblastic T-Cell Lymphoma / Stage III Adult T-Cell Leukemia/Lymphoma / Splenic Marginal Zone Lymphoma / Recurrent Grade 3 Follicular Lymphoma / Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue / Intraocular Lymphoma / Stage III Adult Diffuse Large Cell Lymphoma / Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma / Recurrent Mantle Cell Lymphoma / Recurrent Adult Immunoblastic Large Cell Lymphoma / Stage III Adult Immunoblastic Large Cell Lymphoma / Recurrent Adult Grade III Lymphomatoid Granulomatosis / Stage IV Adult Diffuse Small Cleaved Cell Lymphoma / Adult Grade III Lymphomatoid Granulomatosis / Recurrent Adult T-Cell Leukemia/Lymphoma / Stage III Grade 1 Follicular Lymphoma / Recurrent Small Lymphocytic Lymphoma / Cutaneous B-Cell Non-Hodgkin Lymphoma / Stage IV Adult Burkitt Lymphoma / Stage IV Grade 2 Follicular Lymphoma / Stage III Adult Hodgkin Lymphoma / Small Intestine Lymphoma / Stage IV Adult Lymphoblastic Lymphoma / Recurrent Marginal Zone Lymphoma / Unspecified Adult Solid Tumor, Protocol Specific / Recurrent Adult Hodgkin's Lymphoma / Adult Nasal Type Extranodal NK/T-Cell Lymphoma / Stage IV Mycosis Fungoides/Sezary Syndrome / Recurrent Adult Lymphoblastic Lymphoma / Waldenström's Macroglobulinemia (WM) / Recurrent Adult Burkitt Lymphoma / Stage III Cutaneous T-Cell Non-Hodgkin Lymphoma / Stage IV Adult Diffuse Large Cell Lymphoma / Recurrent Adult Diffuse Large Cell Lymphoma / Stage III Marginal Zone Lymphoma / Stage III Grade 2 Follicular Lymphoma / Stage III Mantle Cell Lymphoma / Stage III Adult Burkitt Lymphoma / Recurrent Mycosis Fungoides/Sezary Syndrome / Recurrent Grade 1 Follicular Lymphoma / Stage IV Marginal Zone Lymphoma / Primary Central Nervous System Hodgkin Lymphoma / Stage III Adult Diffuse Small Cleaved Cell Lymphoma / Recurrent Adult Diffuse Mixed Cell Lymphoma / Stage IV Grade 1 Follicular Lymphoma / Stage III Grade 3 Follicular Lymphoma / Nodal marginal zone B-cell lymphomas / Primary Central Nervous System Non-Hodgkin Lymphoma / Stage IV Adult T-Cell Leukemia/Lymphoma / Recurrent Grade 2 Follicular Lymphoma / Stage IV Mantle Cell Lymphoma / Stage IV Adult Immunoblastic Large Cell Lymphoma / Stage IV Small Lymphocytic Lymphoma / Stage IV Adult Diffuse Mixed Cell Lymphoma / Stage III Adult Lymphoblastic Lymphoma Treatment

IndicationsStatusPurposePhase
CompletedTreatment1
clinicaltrials.gov IdentifierTitleDrugs
NCT00499811Vorinostat in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphoma and Liver Dysfunction
NCT00227513Vorinostat and Bortezomib in Treating Patients With Metastatic or Unresectable Solid Tumors
NCT00324480Vorinostat and Alvocidib in Treating Patients With Advanced Solid Tumors
NCT00287937Vorinostat, Paclitaxel, and Carboplatin in Treating Patients With Advanced or Refractory Solid Tumors
NCT00243100Vorinostat and Gemcitabine in Treating Patients With Metastatic or Unresectable Solid Tumors
NCT00331955Vorinostat and Doxorubicin in Treating Patients With Metastatic or Locally Advanced Solid Tumors
NCT00121277Vorinostat and Capecitabine in Treating Patients With Metastatic or Unresectable Solid Tumors