You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on DrugBank.
Not Available
Identification
NameNeamine
Accession NumberDB04808
TypeSmall Molecule
GroupsExperimental
DescriptionNot Available
Structure
Thumb
Synonyms
Dekamycin V
Nebramycin X
Negamicin
Neomycin A
External Identifiers Not Available
Approved Prescription ProductsNot Available
Approved Generic Prescription ProductsNot Available
Approved Over the Counter ProductsNot Available
Unapproved/Other Products Not Available
International BrandsNot Available
Brand mixturesNot Available
SaltsNot Available
Categories
UNII5981U00LY0
CAS number3947-65-7
WeightAverage: 322.358
Monoisotopic: 322.185234584
Chemical FormulaC12H26N4O6
InChI KeySYJXFKPQNSDJLI-HKEUSBCWSA-N
InChI
InChI=1S/C12H26N4O6/c13-2-5-8(18)9(19)6(16)12(21-5)22-11-4(15)1-3(14)7(17)10(11)20/h3-12,17-20H,1-2,13-16H2/t3-,4+,5-,6-,7+,8-,9-,10-,11-,12-/m1/s1
IUPAC Name
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}oxane-3,4-diol
SMILES
NC[[email protected]]1O[[email protected]](O[C@@H]2[C@@H](N)C[C@@H](N)[[email protected]](O)[[email protected]]2O)[[email protected]](N)[C@@H](O)[C@@H]1O
Pharmacology
IndicationNot Available
Structured Indications Not Available
PharmacodynamicsNot Available
Mechanism of action
Related Articles
AbsorptionNot Available
Volume of distributionNot Available
Protein bindingNot Available
MetabolismNot Available
Route of eliminationNot Available
Half lifeNot Available
ClearanceNot Available
ToxicityNot Available
Affected organismsNot Available
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
Interactions
Drug Interactions
DrugInteractionDrug group
AceclofenacAceclofenac may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
AcetovanilloneAcetovanillone may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
AcetyldigitoxinThe serum concentration of Acetyldigitoxin can be decreased when it is combined with Neamine.Approved
Acetylsalicylic acidAcetylsalicylic acid may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Vet Approved
AdapaleneAdapalene may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
Alendronic acidNeamine may increase the hypocalcemic activities of Alendronic acid.Approved
AmdinocillinThe serum concentration of Neamine can be decreased when it is combined with Amdinocillin.Withdrawn
AmoxicillinThe serum concentration of Neamine can be decreased when it is combined with Amoxicillin.Approved, Vet Approved
Amphotericin BAmphotericin B may increase the nephrotoxic activities of Neamine.Approved, Investigational
AmpicillinThe serum concentration of Neamine can be decreased when it is combined with Ampicillin.Approved, Vet Approved
AnisodamineAnisodamine may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
AntipyrineAntipyrine may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
AnvirzelThe serum concentration of Anvirzel can be decreased when it is combined with Neamine.Investigational
ApremilastApremilast may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
Atracurium besylateNeamine may increase the respiratory depressant activities of Atracurium besylate.Approved
AzapropazoneAzapropazone may decrease the excretion rate of Neamine which could result in a higher serum level.Withdrawn
AzelastineAzelastine may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
AzidocillinThe serum concentration of Neamine can be decreased when it is combined with Azidocillin.Approved
AzlocillinThe serum concentration of Neamine can be decreased when it is combined with Azlocillin.Approved
BacampicillinThe serum concentration of Neamine can be decreased when it is combined with Bacampicillin.Approved
BalsalazideBalsalazide may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
BenoxaprofenBenoxaprofen may decrease the excretion rate of Neamine which could result in a higher serum level.Withdrawn
Benzathine benzylpenicillinThe serum concentration of Neamine can be decreased when it is combined with Benzathine benzylpenicillin.Approved, Vet Approved
BenzylpenicillinThe serum concentration of Neamine can be decreased when it is combined with Benzylpenicillin.Approved, Vet Approved
Benzylpenicillin PotassiumThe serum concentration of Neamine can be decreased when it is combined with Benzylpenicillin Potassium.Approved
Benzylpenicilloyl PolylysineThe serum concentration of Neamine can be decreased when it is combined with Benzylpenicilloyl Polylysine.Approved
Betulinic AcidBetulinic Acid may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
Botulinum Toxin Type ANeamine may increase the neuromuscular blocking activities of Botulinum Toxin Type A.Approved, Investigational
Botulinum Toxin Type BNeamine may increase the neuromuscular blocking activities of Botulinum Toxin Type B.Approved
BromfenacBromfenac may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
BucillamineBucillamine may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
BumetanideThe risk or severity of adverse effects can be increased when Bumetanide is combined with Neamine.Approved
CapreomycinCapreomycin may increase the neuromuscular blocking activities of Neamine.Approved
CarbenicillinThe serum concentration of Neamine can be decreased when it is combined with Carbenicillin.Approved
CarboplatinNeamine may increase the ototoxic activities of Carboplatin.Approved
CarindacillinThe serum concentration of Neamine can be decreased when it is combined with Carindacillin.Approved
CarprofenCarprofen may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Vet Approved, Withdrawn
CastanospermineCastanospermine may decrease the excretion rate of Neamine which could result in a higher serum level.Experimental
CelecoxibCelecoxib may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
ChloroquineChloroquine may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Vet Approved
Cisatracurium besylateNeamine may increase the respiratory depressant activities of Cisatracurium besylate.Approved
CisplatinCisplatin may increase the nephrotoxic activities of Neamine.Approved
ClodronateNeamine may increase the hypocalcemic activities of Clodronate.Approved, Investigational, Vet Approved
ClonixinClonixin may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
CloxacillinThe serum concentration of Neamine can be decreased when it is combined with Cloxacillin.Approved, Vet Approved
ColistimethateNeamine may increase the nephrotoxic activities of Colistimethate.Approved, Vet Approved
CurcuminCurcumin may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
CyclacillinThe serum concentration of Neamine can be decreased when it is combined with Cyclacillin.Approved
CyclosporineNeamine may increase the nephrotoxic activities of Cyclosporine.Approved, Investigational, Vet Approved
D-LimoneneD-Limonene may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
DecamethoniumNeamine may increase the respiratory depressant activities of Decamethonium.Approved
DeslanosideThe serum concentration of Deslanoside can be decreased when it is combined with Neamine.Approved
DiclofenacDiclofenac may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Vet Approved
DicloxacillinThe serum concentration of Neamine can be decreased when it is combined with Dicloxacillin.Approved, Vet Approved
DiflunisalDiflunisal may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
DigitoxinThe serum concentration of Digitoxin can be decreased when it is combined with Neamine.Approved
DigoxinThe serum concentration of Digoxin can be decreased when it is combined with Neamine.Approved
Domoic AcidNeamine may increase the respiratory depressant activities of Domoic Acid.Experimental
Doxacurium chlorideNeamine may increase the respiratory depressant activities of Doxacurium chloride.Approved
DroxicamDroxicam may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
DuvelisibDuvelisib may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
E6201E6201 may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
EbselenEbselen may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
EpirizoleEpirizole may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
Etacrynic acidThe risk or severity of adverse effects can be increased when Etacrynic acid is combined with Neamine.Approved
EtanerceptEtanercept may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
Etidronic acidNeamine may increase the hypocalcemic activities of Etidronic acid.Approved
EtodolacEtodolac may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational, Vet Approved
EtofenamateEtofenamate may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
EtoricoxibEtoricoxib may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
Evening primrose oilEvening primrose oil may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
exisulindexisulind may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
FenbufenFenbufen may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
FenoprofenFenoprofen may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
FloctafenineFloctafenine may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Withdrawn
FlucloxacillinThe serum concentration of Neamine can be decreased when it is combined with Flucloxacillin.Approved
FlunixinFlunixin may decrease the excretion rate of Neamine which could result in a higher serum level.Vet Approved
FlurbiprofenFlurbiprofen may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
FoscarnetFoscarnet may increase the nephrotoxic activities of Neamine.Approved
FurosemideThe risk or severity of adverse effects can be increased when Furosemide is combined with Neamine.Approved, Vet Approved
Gallamine TriethiodideNeamine may increase the respiratory depressant activities of Gallamine Triethiodide.Approved
HigenamineHigenamine may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
HMPL-004HMPL-004 may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
IbandronateNeamine may increase the hypocalcemic activities of Ibandronate.Approved, Investigational
IbuprofenIbuprofen may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
IbuproxamIbuproxam may decrease the excretion rate of Neamine which could result in a higher serum level.Withdrawn
IcatibantIcatibant may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
IndomethacinIndomethacin may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
IndoprofenIndoprofen may decrease the excretion rate of Neamine which could result in a higher serum level.Withdrawn
IsoxicamIsoxicam may decrease the excretion rate of Neamine which could result in a higher serum level.Withdrawn
KebuzoneKebuzone may decrease the excretion rate of Neamine which could result in a higher serum level.Experimental
KetoprofenKetoprofen may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Vet Approved
KetorolacKetorolac may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
LeflunomideLeflunomide may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
LisofyllineLisofylline may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
LornoxicamLornoxicam may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
LoxoprofenLoxoprofen may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
LumiracoxibLumiracoxib may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
Magnesium salicylateMagnesium salicylate may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
MannitolMannitol may increase the nephrotoxic activities of Neamine.Approved, Investigational
MasoprocolMasoprocol may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
MecamylamineNeamine may increase the neuromuscular blocking activities of Mecamylamine.Approved
Meclofenamic acidMeclofenamic acid may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Vet Approved
Mefenamic acidMefenamic acid may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
MeloxicamMeloxicam may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Vet Approved
MesalazineMesalazine may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
MetamizoleMetamizole may decrease the excretion rate of Neamine which could result in a higher serum level.Withdrawn
MeticillinThe serum concentration of Neamine can be decreased when it is combined with Meticillin.Approved
MetocurineNeamine may increase the respiratory depressant activities of Metocurine.Approved
Metocurine IodideNeamine may increase the respiratory depressant activities of Metocurine Iodide.Withdrawn
MezlocillinThe serum concentration of Neamine can be decreased when it is combined with Mezlocillin.Approved
MivacuriumNeamine may increase the respiratory depressant activities of Mivacurium.Approved
MizoribineMizoribine may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
Mycophenolate mofetilMycophenolate mofetil may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
Mycophenolic acidMycophenolic acid may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
NabumetoneNabumetone may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
NafamostatNafamostat may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
NafcillinThe serum concentration of Neamine can be decreased when it is combined with Nafcillin.Approved
NaftifineNaftifine may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
NaproxenNaproxen may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Vet Approved
NCX 4016NCX 4016 may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
NeosaxitoxinNeamine may increase the respiratory depressant activities of Neosaxitoxin.Investigational
NepafenacNepafenac may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
Niflumic AcidNiflumic Acid may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
NimesulideNimesulide may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Withdrawn
NitroaspirinNitroaspirin may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
OlopatadineOlopatadine may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
OlsalazineOlsalazine may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
OrgoteinOrgotein may decrease the excretion rate of Neamine which could result in a higher serum level.Vet Approved
OuabainThe serum concentration of Ouabain can be decreased when it is combined with Neamine.Approved
OxacillinThe serum concentration of Neamine can be decreased when it is combined with Oxacillin.Approved
OxaprozinOxaprozin may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
OxyphenbutazoneOxyphenbutazone may decrease the excretion rate of Neamine which could result in a higher serum level.Withdrawn
PamidronateNeamine may increase the hypocalcemic activities of Pamidronate.Approved
PancuroniumNeamine may increase the respiratory depressant activities of Pancuronium.Approved
ParecoxibParecoxib may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
PhenoxymethylpenicillinThe serum concentration of Neamine can be decreased when it is combined with Phenoxymethylpenicillin.Approved, Vet Approved
PhenylbutazonePhenylbutazone may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Vet Approved
PimecrolimusPimecrolimus may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
PipecuroniumNeamine may increase the respiratory depressant activities of Pipecuronium.Approved
PiperacillinThe serum concentration of Neamine can be decreased when it is combined with Piperacillin.Approved
PiretanideThe risk or severity of adverse effects can be increased when Piretanide is combined with Neamine.Experimental
PirfenidonePirfenidone may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
PiroxicamPiroxicam may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
PivampicillinThe serum concentration of Neamine can be decreased when it is combined with Pivampicillin.Approved
PivmecillinamThe serum concentration of Neamine can be decreased when it is combined with Pivmecillinam.Approved
Procaine benzylpenicillinThe serum concentration of Neamine can be decreased when it is combined with Procaine benzylpenicillin.Approved, Vet Approved
PropacetamolPropacetamol may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
PTC299PTC299 may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
PyrantelNeamine may increase the respiratory depressant activities of Pyrantel.Approved, Vet Approved
RapacuroniumNeamine may increase the respiratory depressant activities of Rapacuronium.Withdrawn
ResveratrolResveratrol may decrease the excretion rate of Neamine which could result in a higher serum level.Experimental, Investigational
RisedronateNeamine may increase the hypocalcemic activities of Risedronate.Approved, Investigational
RocuroniumNeamine may increase the respiratory depressant activities of Rocuronium.Approved
RofecoxibRofecoxib may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational, Withdrawn
SalicylamideSalicylamide may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
Salicylic acidSalicylic acid may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Vet Approved
SalsalateSalsalate may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
SeratrodastSeratrodast may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
SRT501SRT501 may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
SuccinylcholineNeamine may increase the respiratory depressant activities of Succinylcholine.Approved
SulbactamThe serum concentration of Neamine can be decreased when it is combined with Sulbactam.Approved
SulfasalazineSulfasalazine may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
SulindacSulindac may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
SultamicillinThe serum concentration of Neamine can be decreased when it is combined with Sultamicillin.Investigational
SuprofenSuprofen may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Withdrawn
TazobactamThe serum concentration of Neamine can be decreased when it is combined with Tazobactam.Approved
Technetium tc 99m etidronateNeamine may increase the hypocalcemic activities of Technetium tc 99m etidronate.Approved
Technetium Tc-99m MedronateNeamine may increase the hypocalcemic activities of Technetium Tc-99m Medronate.Approved
TenofovirThe serum concentration of Neamine can be increased when it is combined with Tenofovir.Approved, Investigational
TenoxicamTenoxicam may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
TepoxalinTepoxalin may decrease the excretion rate of Neamine which could result in a higher serum level.Vet Approved
TeriflunomideTeriflunomide may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
Tiaprofenic acidTiaprofenic acid may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
TicarcillinThe serum concentration of Neamine can be decreased when it is combined with Ticarcillin.Approved, Vet Approved
TiludronateNeamine may increase the hypocalcemic activities of Tiludronate.Approved, Vet Approved
TinoridineTinoridine may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational
Tolfenamic AcidTolfenamic Acid may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
TolmetinTolmetin may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
TorasemideThe risk or severity of adverse effects can be increased when Torasemide is combined with Neamine.Approved
TranilastTranilast may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational
Trisalicylate-cholineTrisalicylate-choline may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
TubocurarineNeamine may increase the respiratory depressant activities of Tubocurarine.Approved
ValdecoxibValdecoxib may decrease the excretion rate of Neamine which could result in a higher serum level.Investigational, Withdrawn
VancomycinVancomycin may increase the nephrotoxic activities of Neamine.Approved
VecuroniumNeamine may increase the respiratory depressant activities of Vecuronium.Approved
ZaltoprofenZaltoprofen may decrease the excretion rate of Neamine which could result in a higher serum level.Approved
ZileutonZileuton may decrease the excretion rate of Neamine which could result in a higher serum level.Approved, Investigational, Withdrawn
Zoledronic acidNeamine may increase the hypocalcemic activities of Zoledronic acid.Approved
ZomepiracZomepirac may decrease the excretion rate of Neamine which could result in a higher serum level.Withdrawn
Food InteractionsNot Available
References
Synthesis Reference

Eiichi Akita, Tsutomu Tsuchiya, Shinichi Kondo, Shuntaro Yasuda, Sumio Umezawa, Hamao Umezawa, “1-N-((S)-.alpha.-substituted-.omega.-aminoacyl)-neamine or -ribostamycin and the production thereof.” U.S. Patent US4008218, issued February, 1974.

US4008218
General ReferencesNot Available
External Links
ATC CodesNot Available
AHFS CodesNot Available
PDB EntriesNot Available
FDA labelNot Available
MSDSNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption-0.8567
Blood Brain Barrier-0.9659
Caco-2 permeable-0.7666
P-glycoprotein substrateSubstrate0.5
P-glycoprotein inhibitor INon-inhibitor0.7518
P-glycoprotein inhibitor IINon-inhibitor0.8382
Renal organic cation transporterNon-inhibitor0.8516
CYP450 2C9 substrateNon-substrate0.8033
CYP450 2D6 substrateNon-substrate0.8275
CYP450 3A4 substrateNon-substrate0.6391
CYP450 1A2 substrateNon-inhibitor0.9186
CYP450 2C9 inhibitorNon-inhibitor0.9257
CYP450 2D6 inhibitorNon-inhibitor0.9224
CYP450 2C19 inhibitorNon-inhibitor0.9062
CYP450 3A4 inhibitorNon-inhibitor0.9569
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.914
Ames testNon AMES toxic0.6928
CarcinogenicityNon-carcinogens0.952
BiodegradationNot ready biodegradable0.7421
Rat acute toxicity1.6749 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9779
hERG inhibition (predictor II)Non-inhibitor0.8599
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
ManufacturersNot Available
PackagersNot Available
Dosage formsNot Available
PricesNot Available
PatentsNot Available
Properties
StateSolid
Experimental PropertiesNot Available
Predicted Properties
PropertyValueSource
Water Solubility101.0 mg/mLALOGPS
logP-2.9ALOGPS
logP-5.3ChemAxon
logS-0.5ALOGPS
pKa (Strongest Acidic)12.66ChemAxon
pKa (Strongest Basic)9.67ChemAxon
Physiological Charge4ChemAxon
Hydrogen Acceptor Count10ChemAxon
Hydrogen Donor Count8ChemAxon
Polar Surface Area203.46 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity73.72 m3·mol-1ChemAxon
Polarizability32.19 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability0ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as aminoglycosides. These are molecules or a portion of a molecule composed of amino-modified sugars.
KingdomOrganic compounds
Super ClassOrganooxygen compounds
ClassCarbohydrates and carbohydrate conjugates
Sub ClassAminosaccharides
Direct ParentAminoglycosides
Alternative Parents
Substituents
  • Aminoglycoside core
  • 2-deoxystreptamine aminoglycoside
  • Neamine core
  • Glucosamine
  • Amino sugar
  • O-glycosyl compound
  • Glycosyl compound
  • Cyclohexylamine
  • Cyclohexanol
  • Oxane
  • Monosaccharide
  • Cyclic alcohol
  • Secondary alcohol
  • 1,2-diol
  • 1,2-aminoalcohol
  • Oxacycle
  • Organoheterocyclic compound
  • Acetal
  • Hydrocarbon derivative
  • Primary amine
  • Organonitrogen compound
  • Primary aliphatic amine
  • Amine
  • Alcohol
  • Aliphatic heteromonocyclic compound
Molecular FrameworkAliphatic heteromonocyclic compounds
External Descriptors
Comments
comments powered by Disqus
Drug created on September 11, 2007 11:49 / Updated on August 17, 2016 12:24