Tagatose is a functional sweetener. It is a naturally occurring monosaccharide, specifically a hexose. It is often found in dairy products, and is very similar in texture to sucrose (table sugar) and is 92% as sweet, but with only 38% of the calories. It is approved as a food additive as a low calorie sweetener. Additionally, it is under investigation by Spherix for the treatment of obesity and type II diabetes.
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|Weight||Average: 180.1559 |
Intended for use as a therapeutic adjunct in the treatment of type II diabetes.
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Oral tagatose significantly blunts the rise in plasma glucose seen after oral glucose in patients with diabetes mellitus in a dose-dependent manner without significantly affecting insulin levels. The minimal elevation of plasma tagatose levels in normal patients and the adverse gastrointestinal effects seen following larger doses of tagatose support poor absorption of this hexose and suggest that tagatose may act by attenuating glucose absorption in the intestine.
|Mechanism of action|
he steps in the metabolism of tagatose are identical to those for fructose or fruit sugar but tagatose is incompletely absorbed. Only 15-20 percent of tagatose is absorbed in the small intestine. The major part of ingested tagatose is fermented in the colon by indigenous microflora, resulting in the production of short-chain fatty acids. The short chain fatty acids are absorbed almost completely and metabolized.
Only 15-20 percent of tagatose is absorbed in the small intestine.
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Since it is metabolized differently from sucrose, tagatose has a minimal effect on blood glucose and insulin levels.
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|MSDS||Download (69.8 KB)|
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|Description||This compound belongs to the class of chemical entities known as monosaccharides. These are compounds containing one carbohydrate unit not glycosidically linked to another such unit, and no set of two or more glycosidically linked carbohydrate units. Monosaccharides have the general formula CnH2nOn.|
|Super Class||Organic compounds|
|Class||Organic oxygen compounds|
|Sub Class||Organooxygen compounds|
|Alternative Parents||Beta-hydroxy ketones / Acyloins / Alpha-hydroxy ketones / Secondary alcohols / Polyols / Primary alcohols / Organic oxides / Hydrocarbon derivatives|
|Substituents||Monosaccharide / Beta-hydroxy ketone / Acyloin / Alpha-hydroxy ketone / Secondary alcohol / Ketone / Polyol / Organic oxide / Hydrocarbon derivative / Primary alcohol|
|Molecular Framework||Aliphatic acyclic compounds|
|External Descriptors||tagatose, D-tagatose (CHEBI:47693 )|