Showing BioInteractions for Lucanthone (DB04967)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Lucanthone is a DNA topoisomerase 2-alpha inhibitor
1DNA topoisomerase 2-alpha inhibitorsAldoxorubicin, Amsacrine, Ciprofloxacin, Daunorubicin, Dexrazoxane, Doxorubicin, Enoxacin, Epirubicin, Etoposide, Finafloxacin, Fleroxacin, Idarubicin, Lomefloxacin, Mitoxantrone, Moxifloxacin, Norfloxacin, Ofloxacin, Pefloxacin, Podofilox, Sparfloxacin, Teniposide, Trovafloxacin, Valrubicin
Interacting GroupInteracting Drugs
Lucanthone is a DNA-(apurinic or apyrimidinic site) lyase inhibitor
Interacting GroupInteracting Drugs
Lucanthone is a DNA topoisomerase 1 inhibitor
1DNA topoisomerase 1 inhibitorsHexylresorcinol, Irinotecan, Sacituzumab govitecan, Sodium stibogluconate, Topotecan, Trastuzumab deruxtecan