Showing BioInteractions for Ibudilast (DB05266)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ibudilast is a cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor | ||
| 1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitors | Crisaborole, Dipyridamole, Drotaverine, Dyphylline, Enprofylline, Oxtriphylline, Roflumilast, Theophylline, Tofisopam |
| 2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4A inducers | Iloprost |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ibudilast is a cGMP-inhibited 3',5'-cyclic phosphodiesterase A inhibitor | ||
| 1 | cGMP-inhibited 3',5'-cyclic phosphodiesterase A inhibitors | Aminophylline, Amrinone, Anagrelide, Cilostazol, Enoximone, Levosimendan, Milrinone, Oxtriphylline, Theophylline, Tofisopam |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ibudilast is a cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor | ||
| 1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitors | (R)-Rolipram, (S)-Rolipram, Caffeine, Cilomilast, Crisaborole, Dyphylline, Enprofylline, Filaminast, Papaverine, Roflumilast, Theobromine, Theophylline |
| 2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B inducers | Iloprost |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ibudilast is a cAMP-specific 3',5'-cyclic phosphodiesterase 4C inhibitor | ||
| 1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4C inhibitors | Crisaborole, Dyphylline, Roflumilast |
| 2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4C inducers | Iloprost |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Ibudilast is a cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor | ||
| 1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitors | Cilomilast, Crisaborole, Dyphylline, Roflumilast |
| 2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D inducers | Iloprost |