Showing BioInteractions for Histamine (DB05381)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting Group | Interacting Drugs | |
---|---|---|
Histamine is a Histamine H2 receptor agonist | ||
1 | Histamine H2 receptor agonists | Betazole, Tolazoline |
2 | Histamine H2 receptor antagonists | Asenapine, Cimetidine, Doxepin, Epinastine, Famotidine, Methantheline, Metiamide, Nizatidine, Olopatadine, Promethazine, Ranitidine, Roxatidine acetate |
3 | Histamine H2 receptor binders | Loxapine |
4 | Histamine H2 receptor blockers | Amitriptyline |
5 | Histamine H2 receptor inhibitors | Azelastine |
6 | Histamine H2 receptor ligands | Aripiprazole |
Interacting Group | Interacting Drugs | |
---|---|---|
Histamine is a Histamine H3 receptor agonist | ||
1 | Histamine H3 receptor antagonists | Betahistine, Olopatadine, Pitolisant |
2 | Histamine H3 receptor inverse agonists | Pitolisant |
3 | Histamine H3 receptor ligands | Aripiprazole |
Interacting Group | Interacting Drugs | |
---|---|---|
Histamine is a Histamine H4 receptor agonist | ||
1 | Histamine H4 receptor antagonists | Clozapine |
2 | Histamine H4 receptor binders | Amitriptyline, Amoxapine, Chlorpromazine, Doxepin, Loxapine, Mianserin |
3 | Histamine H4 receptor inverse agonists | Pheniramine |
4 | Histamine H4 receptor ligands | Aripiprazole |
Interacting Group | Interacting Drugs | |
---|---|---|
Histamine is a Histamine N-methyltransferase substrate | ||
1 | Histamine N-methyltransferase inhibitors | Amodiaquine, Harmaline, Quinacrine, S-adenosyl-L-homocysteine |
2 | Histamine N-methyltransferase binders | S-adenosyl-L-homocysteine |
Interacting Group | Interacting Drugs | |
---|---|---|
Histamine is a Solute carrier family 22 member 3 inhibitor | ||
1 | Solute carrier family 22 member 3 inhibitors | Choline, Choline salicylate, Cimetidine, Clonidine, Desipramine, Dopamine, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Formoterol, Guanidine, Imipramine, Irinotecan, Linagliptin, Melphalan, Metamfetamine, Nicotine, Norepinephrine, Phenoxybenzamine, Prazosin, Procainamide, Progesterone, Salmeterol, Vincristine |
2 | Solute carrier family 22 member 3 substrates | Adefovir dipivoxil, Agmatine, Amphetamine, Cimetidine, Guanidine, Lamivudine, Metformin, Norepinephrine, Oxaliplatin, Sulpiride, Testosterone cypionate, Testosterone enanthate |
Interacting Group | Interacting Drugs | |
---|---|---|
Histamine is a Solute carrier family 22 member 5 inhibitor | ||
1 | Solute carrier family 22 member 5 inhibitors | Acetylcholine, Aldosterone, Aminohippuric acid, Ampicillin, Arginine, Azidocillin, Benzylpenicillin, Cefadroxil, Cefalotin, Cefdinir, Cefepime, Cefixime, Cefradine, Ceftazidime, Cephalexin, Cephaloglycin, Choline, Choline salicylate, Cimetidine, Clonidine, Creatine, Cyclacillin, Dactinomycin, Desipramine, Diphenhydramine, Dopamine, Furosemide, Grepafloxacin, Guanidine, Levamlodipine, Lidocaine, Lomefloxacin, Metamfetamine, Methacholine, Niacin, Nicotine, Norepinephrine, Norfloxacin, Ofloxacin, Probenecid, Procainamide, Quinidine, Quinine, Sparfloxacin, Thiamine, Valproic acid, Verapamil |
2 | Solute carrier family 22 member 5 substrates | Amphetamine, Formoterol, Ipratropium, Levocarnitine, Terbutaline, Tiotropium |