AMG 108

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
AMG 108
Accession Number
DB05545
Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Other protein based therapies
Description

AMG 108 was investigated for use as an antirheumatic agent.

Protein chemical formula
Not Available
Protein average weight
Not Available
Sequences
Not Available
Synonyms
Not Available
External IDs
AMG 108 / AMG-108
Categories
UNII
Not Available
CAS number
877879-38-4

Pharmacology

Indication

Investigated for use/treatment in osteoarthritis and rheumatoid arthritis.

Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteraction
AbciximabThe risk or severity of adverse effects can be increased when Abciximab is combined with AMG 108.
AbituzumabThe risk or severity of adverse effects can be increased when AMG 108 is combined with Abituzumab.
AbrilumabThe risk or severity of adverse effects can be increased when AMG 108 is combined with Abrilumab.
AdalimumabThe risk or severity of adverse effects can be increased when Adalimumab is combined with AMG 108.
AdecatumumabThe risk or severity of adverse effects can be increased when Adecatumumab is combined with AMG 108.
AducanumabThe risk or severity of adverse effects can be increased when AMG 108 is combined with Aducanumab.
AfelimomabThe risk or severity of adverse effects can be increased when Afelimomab is combined with AMG 108.
AlemtuzumabThe risk or severity of adverse effects can be increased when Alemtuzumab is combined with AMG 108.
AlirocumabThe risk or severity of adverse effects can be increased when AMG 108 is combined with Alirocumab.
AmatuximabThe risk or severity of adverse effects can be increased when AMG 108 is combined with Amatuximab.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

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  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

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  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

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Food Interactions
Not Available

References

General References
Not Available
External Links
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedTreatmentRheumatoid Arthritis2
2WithdrawnPreventionDiabetes Mellitus (DM)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available

Taxonomy

Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available

Drug created on November 18, 2007 11:25 / Updated on June 04, 2019 06:18