This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
ANZ-100
Accession Number
DB05967
Type
Small Molecule
Groups
Investigational
Description
Not Available
Synonyms
Not Available
External IDs
ANZ 100 / ANZ100 / CRS-100 / CRS100
Categories
Not Available
UNII
7UKM1TA46L
CAS number
Not Available
Weight
Not Available
Chemical Formula
Not Available
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

Pharmacology

Indication

Investigated for use/treatment in cancer/tumors (unspecified) and liver cancer.

Pharmacodynamics
Not Available
Mechanism of action

CRS-100 is a bacteria-based immune therapy that targets liver metastases. Liver metastases arise from a number of cancers, including colon and pancreas cancers. Despite recent advances, metastasized colorectal and pancreatic cancers remain significant unmet medical needs.

TargetActionsOrganism
UKiSS-1 receptorNot AvailableHumans
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedTreatmentCarcinoma NOS / Neoplasms Metastasis / Neoplasms, Hepatic1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Targets

Kind
Protein
Organism
Humans
Pharmacological action
Unknown
General Function
Neuropeptide receptor activity
Specific Function
Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some brea...
Gene Name
KISS1R
Uniprot ID
Q969F8
Uniprot Name
KiSS-1 receptor
Molecular Weight
42585.445 Da

Drug created on November 18, 2007 11:29 / Updated on June 04, 2019 06:20