Pizotifen

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Pizotifen
Accession Number
DB06153
Type
Small Molecule
Groups
Approved
Description
Not Available
Structure
Thumb
Synonyms
  • Pizotyline
External IDs
BC-105
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
SandomigranTablet0.50 mgOralPaladin Labs Inc1975-01-01Not applicableCanada
Sandomigran DSTablet1 mgOralPaladin Labs Inc1980-12-31Not applicableCanada
Categories
UNII
0BY8440V3N
CAS number
Not Available
Weight
Average: 295.44
Monoisotopic: 295.139470854
Chemical Formula
C19H21NS
InChI Key
FIADGNVRKBPQEU-UHFFFAOYSA-N
InChI
InChI=1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
IUPAC Name
1-methyl-4-{6-thiatricyclo[8.4.0.0³,⁷]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene}piperidine
SMILES
CN1CCC(CC1)=C1C2=C(CCC3=CC=CC=C13)SC=C2

Pharmacology

Indication
Not Available
Structured Indications
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with Pizotifen.Experimental
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline may increase the anticholinergic activities of Pizotifen.Experimental
AcepromazineThe risk or severity of adverse effects can be increased when Acepromazine is combined with Pizotifen.Approved, Vet Approved
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with Pizotifen.Approved
AdipiplonThe risk or severity of adverse effects can be increased when Adipiplon is combined with Pizotifen.Investigational
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Pizotifen.Approved, Investigational
AlaproclateThe risk or severity of adverse effects can be increased when Pizotifen is combined with Alaproclate.Experimental
AlfaxaloneThe risk or severity of adverse effects can be increased when Alfaxalone is combined with Pizotifen.Vet Approved
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Pizotifen.Approved, Illicit
AllopregnanoloneThe risk or severity of adverse effects can be increased when Allopregnanolone is combined with Pizotifen.Investigational
AlphacetylmethadolThe risk or severity of adverse effects can be increased when Alphacetylmethadol is combined with Pizotifen.Experimental, Illicit
AlphaprodineThe risk or severity of adverse effects can be increased when Alphaprodine is combined with Pizotifen.Illicit
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Pizotifen.Approved, Illicit, Investigational
AmisulprideThe risk or severity of adverse effects can be increased when Amisulpride is combined with Pizotifen.Approved, Investigational
AmitriptylineThe risk or severity of adverse effects can be increased when Amitriptyline is combined with Pizotifen.Approved
AmobarbitalThe risk or severity of adverse effects can be increased when Amobarbital is combined with Pizotifen.Approved, Illicit
AmoxapineThe risk or severity of adverse effects can be increased when Amoxapine is combined with Pizotifen.Approved
AmperozideThe risk or severity of adverse effects can be increased when Amperozide is combined with Pizotifen.Experimental
AripiprazoleThe risk or severity of adverse effects can be increased when Aripiprazole is combined with Pizotifen.Approved, Investigational
ArticaineThe risk or severity of adverse effects can be increased when Articaine is combined with Pizotifen.Approved
AsenapineThe risk or severity of adverse effects can be increased when Asenapine is combined with Pizotifen.Approved
AzaperoneThe risk or severity of adverse effects can be increased when Azaperone is combined with Pizotifen.Vet Approved
AzelastinePizotifen may increase the central nervous system depressant (CNS depressant) activities of Azelastine.Approved
BaclofenThe risk or severity of adverse effects can be increased when Baclofen is combined with Pizotifen.Approved
BarbitalThe risk or severity of adverse effects can be increased when Barbital is combined with Pizotifen.Illicit
BenmoxinBenmoxin may increase the anticholinergic activities of Pizotifen.Withdrawn
BenperidolThe risk or severity of adverse effects can be increased when Benperidol is combined with Pizotifen.Investigational
BenzocaineThe risk or severity of adverse effects can be increased when Benzocaine is combined with Pizotifen.Approved
Benzyl alcoholThe risk or severity of adverse effects can be increased when Benzyl alcohol is combined with Pizotifen.Approved
BrexpiprazoleThe risk or severity of adverse effects can be increased when Pizotifen is combined with Brexpiprazole.Approved
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.Approved
BrofaromineBrofaromine may increase the anticholinergic activities of Pizotifen.Experimental
BromazepamThe risk or severity of adverse effects can be increased when Bromazepam is combined with Pizotifen.Approved, Illicit
BromisovalThe risk or severity of adverse effects can be increased when Bromisoval is combined with Pizotifen.Experimental
BromperidolThe risk or severity of adverse effects can be increased when Bromperidol is combined with Pizotifen.Investigational
BrompheniramineThe risk or severity of adverse effects can be increased when Brompheniramine is combined with Pizotifen.Approved
BrotizolamThe risk or severity of adverse effects can be increased when Brotizolam is combined with Pizotifen.Approved, Withdrawn
BupivacaineThe risk or severity of adverse effects can be increased when Bupivacaine is combined with Pizotifen.Approved, Investigational
BuprenorphinePizotifen may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.Approved, Illicit, Investigational, Vet Approved
BuspironeThe risk or severity of adverse effects can be increased when Buspirone is combined with Pizotifen.Approved, Investigational
ButabarbitalThe risk or severity of adverse effects can be increased when Butabarbital is combined with Pizotifen.Approved, Illicit
ButacaineThe risk or severity of adverse effects can be increased when Butacaine is combined with Pizotifen.Vet Approved
ButalbitalThe risk or severity of adverse effects can be increased when Butalbital is combined with Pizotifen.Approved, Illicit
ButambenThe risk or severity of adverse effects can be increased when Butamben is combined with Pizotifen.Approved
ButethalThe risk or severity of adverse effects can be increased when Butethal is combined with Pizotifen.Approved, Illicit
ButorphanolThe risk or severity of adverse effects can be increased when Butorphanol is combined with Pizotifen.Approved, Illicit, Vet Approved
CanertinibThe risk or severity of adverse effects can be increased when Canertinib is combined with Pizotifen.Investigational
CarbamazepineThe risk or severity of adverse effects can be increased when Carbamazepine is combined with Pizotifen.Approved, Investigational
CarbinoxamineThe risk or severity of adverse effects can be increased when Carbinoxamine is combined with Pizotifen.Approved
CarfentanilThe risk or severity of adverse effects can be increased when Carfentanil is combined with Pizotifen.Illicit, Vet Approved
CarisoprodolThe risk or severity of adverse effects can be increased when Carisoprodol is combined with Pizotifen.Approved
CaroxazoneCaroxazone may increase the anticholinergic activities of Pizotifen.Withdrawn
CetirizineThe risk or severity of adverse effects can be increased when Cetirizine is combined with Pizotifen.Approved
Chloral hydrateThe risk or severity of adverse effects can be increased when Chloral hydrate is combined with Pizotifen.Approved, Illicit, Vet Approved
ChlordiazepoxideThe risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Pizotifen.Approved, Illicit
ChlormezanoneThe risk or severity of adverse effects can be increased when Chlormezanone is combined with Pizotifen.Approved, Withdrawn
ChloroprocaineThe risk or severity of adverse effects can be increased when Chloroprocaine is combined with Pizotifen.Approved
ChlorphenamineThe risk or severity of adverse effects can be increased when Chlorphenamine is combined with Pizotifen.Approved
ChlorpromazineThe risk or severity of adverse effects can be increased when Chlorpromazine is combined with Pizotifen.Approved, Vet Approved
ChlorprothixeneThe risk or severity of adverse effects can be increased when Chlorprothixene is combined with Pizotifen.Approved, Withdrawn
ChlorzoxazoneThe risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Pizotifen.Approved
CinchocaineThe risk or severity of adverse effects can be increased when Cinchocaine is combined with Pizotifen.Approved, Vet Approved
CitalopramThe risk or severity of adverse effects can be increased when Pizotifen is combined with Citalopram.Approved
ClemastineThe risk or severity of adverse effects can be increased when Clemastine is combined with Pizotifen.Approved
ClidiniumThe risk or severity of adverse effects can be increased when Clidinium is combined with Pizotifen.Approved
ClobazamThe risk or severity of adverse effects can be increased when Clobazam is combined with Pizotifen.Approved, Illicit
clomethiazoleThe risk or severity of adverse effects can be increased when clomethiazole is combined with Pizotifen.Investigational
ClomipramineThe risk or severity of adverse effects can be increased when Clomipramine is combined with Pizotifen.Approved, Vet Approved
ClonazepamThe risk or severity of adverse effects can be increased when Clonazepam is combined with Pizotifen.Approved, Illicit
ClonidineThe risk or severity of adverse effects can be increased when Clonidine is combined with Pizotifen.Approved
ClopenthixolThe risk or severity of adverse effects can be increased when Clopenthixol is combined with Pizotifen.Experimental
ClorazepateThe risk or severity of adverse effects can be increased when Clorazepate is combined with Pizotifen.Approved, Illicit
ClothiapineThe risk or severity of adverse effects can be increased when Clothiapine is combined with Pizotifen.Experimental
ClozapineThe risk or severity of adverse effects can be increased when Clozapine is combined with Pizotifen.Approved
CocaineThe risk or severity of adverse effects can be increased when Cocaine is combined with Pizotifen.Approved, Illicit
CodeineThe risk or severity of adverse effects can be increased when Codeine is combined with Pizotifen.Approved, Illicit
CyclizineThe risk or severity of adverse effects can be increased when Cyclizine is combined with Pizotifen.Approved
CyclobenzaprineThe risk or severity of adverse effects can be increased when Cyclobenzaprine is combined with Pizotifen.Approved
CyproheptadineThe risk or severity of adverse effects can be increased when Cyproheptadine is combined with Pizotifen.Approved
DantroleneThe risk or severity of adverse effects can be increased when Dantrolene is combined with Pizotifen.Approved
DapiprazoleThe risk or severity of adverse effects can be increased when Dapiprazole is combined with Pizotifen.Approved
DapoxetineThe risk or severity of adverse effects can be increased when Pizotifen is combined with Dapoxetine.Investigational
DeramciclaneThe risk or severity of adverse effects can be increased when Deramciclane is combined with Pizotifen.Investigational
DesfluraneThe risk or severity of adverse effects can be increased when Desflurane is combined with Pizotifen.Approved
DesipramineThe risk or severity of adverse effects can be increased when Desipramine is combined with Pizotifen.Approved
DesloratadineThe risk or severity of adverse effects can be increased when Desloratadine is combined with Pizotifen.Approved, Investigational
DesvenlafaxineThe risk or severity of adverse effects can be increased when Pizotifen is combined with Desvenlafaxine.Approved
DetomidineThe risk or severity of adverse effects can be increased when Detomidine is combined with Pizotifen.Vet Approved
DexbrompheniramineThe risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Pizotifen.Approved
DexmedetomidineThe risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Pizotifen.Approved, Vet Approved
DextromoramideThe risk or severity of adverse effects can be increased when Dextromoramide is combined with Pizotifen.Experimental, Illicit
DextropropoxypheneThe risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Pizotifen.Approved, Illicit, Withdrawn
DezocineThe risk or severity of adverse effects can be increased when Dezocine is combined with Pizotifen.Approved
DiazepamThe risk or severity of adverse effects can be increased when Diazepam is combined with Pizotifen.Approved, Illicit, Vet Approved
Diethyl etherThe risk or severity of adverse effects can be increased when Diethyl ether is combined with Pizotifen.Experimental
DifenoxinThe risk or severity of adverse effects can be increased when Difenoxin is combined with Pizotifen.Approved, Illicit
DihydrocodeineThe risk or severity of adverse effects can be increased when Dihydrocodeine is combined with Pizotifen.Approved, Illicit
DihydroetorphineThe risk or severity of adverse effects can be increased when Dihydroetorphine is combined with Pizotifen.Experimental, Illicit
DihydromorphineThe risk or severity of adverse effects can be increased when Dihydromorphine is combined with Pizotifen.Experimental, Illicit
DimenhydrinateThe risk or severity of adverse effects can be increased when Dimenhydrinate is combined with Pizotifen.Approved
DiphenhydramineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Pizotifen.Approved
DiphenoxylateThe risk or severity of adverse effects can be increased when Diphenoxylate is combined with Pizotifen.Approved, Illicit
DixyrazineThe risk or severity of adverse effects can be increased when Dixyrazine is combined with Pizotifen.Experimental
DoramectinThe risk or severity of adverse effects can be increased when Doramectin is combined with Pizotifen.Vet Approved
DoxepinThe risk or severity of adverse effects can be increased when Doxepin is combined with Pizotifen.Approved
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.Approved, Vet Approved
DPDPEThe risk or severity of adverse effects can be increased when DPDPE is combined with Pizotifen.Investigational
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.Approved, Illicit
DroperidolDroperidol may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.Approved, Vet Approved
DrotebanolThe risk or severity of adverse effects can be increased when Drotebanol is combined with Pizotifen.Experimental, Illicit
DuloxetineThe risk or severity of adverse effects can be increased when Pizotifen is combined with Duloxetine.Approved
DyclonineThe risk or severity of adverse effects can be increased when Dyclonine is combined with Pizotifen.Approved
EcgonineThe risk or severity of adverse effects can be increased when Ecgonine is combined with Pizotifen.Experimental, Illicit
EcopipamThe risk or severity of adverse effects can be increased when Ecopipam is combined with Pizotifen.Investigational
EfavirenzThe risk or severity of adverse effects can be increased when Efavirenz is combined with Pizotifen.Approved, Investigational
EltanoloneThe risk or severity of adverse effects can be increased when Eltanolone is combined with Pizotifen.Investigational
EnfluraneThe risk or severity of adverse effects can be increased when Enflurane is combined with Pizotifen.Approved, Vet Approved
EntacaponeThe risk or severity of adverse effects can be increased when Entacapone is combined with Pizotifen.Approved, Investigational
EscitalopramThe risk or severity of adverse effects can be increased when Pizotifen is combined with Escitalopram.Approved, Investigational
EstazolamThe risk or severity of adverse effects can be increased when Estazolam is combined with Pizotifen.Approved, Illicit
EszopicloneThe risk or severity of adverse effects can be increased when Eszopiclone is combined with Pizotifen.Approved
EthanolPizotifen may increase the central nervous system depressant (CNS depressant) activities of Ethanol.Approved
EthchlorvynolThe risk or severity of adverse effects can be increased when Ethchlorvynol is combined with Pizotifen.Approved, Illicit, Withdrawn
EthosuximideThe risk or severity of adverse effects can be increased when Ethosuximide is combined with Pizotifen.Approved
EthotoinThe risk or severity of adverse effects can be increased when Ethotoin is combined with Pizotifen.Approved
Ethyl carbamateThe risk or severity of adverse effects can be increased when Ethyl carbamate is combined with Pizotifen.Withdrawn
Ethyl chlorideThe risk or severity of adverse effects can be increased when Ethyl chloride is combined with Pizotifen.Experimental
Ethyl loflazepateThe risk or severity of adverse effects can be increased when Ethyl loflazepate is combined with Pizotifen.Approved, Illicit
EthylmorphineThe risk or severity of adverse effects can be increased when Ethylmorphine is combined with Pizotifen.Approved, Illicit
EtidocaineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Pizotifen.Approved
EtifoxineThe risk or severity of adverse effects can be increased when Etifoxine is combined with Pizotifen.Withdrawn
EtizolamThe risk or severity of adverse effects can be increased when Etizolam is combined with Pizotifen.Approved
EtomidateThe risk or severity of adverse effects can be increased when Etomidate is combined with Pizotifen.Approved
EtoperidoneThe risk or severity of adverse effects can be increased when Pizotifen is combined with Etoperidone.Approved
EtorphineThe risk or severity of adverse effects can be increased when Etorphine is combined with Pizotifen.Illicit, Vet Approved
EzogabineThe risk or severity of adverse effects can be increased when Ezogabine is combined with Pizotifen.Approved
FelbamateThe risk or severity of adverse effects can be increased when Felbamate is combined with Pizotifen.Approved
FencamfamineThe risk or severity of adverse effects can be increased when Fencamfamine is combined with Pizotifen.Approved, Illicit, Withdrawn
FentanylThe risk or severity of adverse effects can be increased when Fentanyl is combined with Pizotifen.Approved, Illicit, Investigational, Vet Approved
FexofenadineThe risk or severity of adverse effects can be increased when Fexofenadine is combined with Pizotifen.Approved
FlibanserinThe risk or severity of adverse effects can be increased when Flibanserin is combined with Pizotifen.Approved
FluanisoneThe risk or severity of adverse effects can be increased when Fluanisone is combined with Pizotifen.Experimental
FludiazepamThe risk or severity of adverse effects can be increased when Fludiazepam is combined with Pizotifen.Approved, Illicit
FlunarizineThe risk or severity of adverse effects can be increased when Flunarizine is combined with Pizotifen.Approved
FlunitrazepamThe risk or severity of adverse effects can be increased when Flunitrazepam is combined with Pizotifen.Approved, Illicit
FluoxetineThe risk or severity of adverse effects can be increased when Pizotifen is combined with Fluoxetine.Approved, Vet Approved
FlupentixolThe risk or severity of adverse effects can be increased when Flupentixol is combined with Pizotifen.Approved, Withdrawn
FluphenazineThe risk or severity of adverse effects can be increased when Fluphenazine is combined with Pizotifen.Approved
FlurazepamThe risk or severity of adverse effects can be increased when Flurazepam is combined with Pizotifen.Approved, Illicit
FluspirileneThe risk or severity of adverse effects can be increased when Fluspirilene is combined with Pizotifen.Approved
Fluticasone propionateThe risk or severity of adverse effects can be increased when Fluticasone propionate is combined with Pizotifen.Approved
FluvoxamineThe risk or severity of adverse effects can be increased when Fluvoxamine is combined with Pizotifen.Approved, Investigational
FosphenytoinThe risk or severity of adverse effects can be increased when Fosphenytoin is combined with Pizotifen.Approved
FospropofolThe risk or severity of adverse effects can be increased when Fospropofol is combined with Pizotifen.Approved, Illicit
FurazolidoneFurazolidone may increase the anticholinergic activities of Pizotifen.Approved, Vet Approved
GabapentinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Pizotifen.Approved, Investigational
Gabapentin EnacarbilThe risk or severity of adverse effects can be increased when Pizotifen is combined with Gabapentin Enacarbil.Approved
Gamma Hydroxybutyric AcidThe risk or severity of adverse effects can be increased when Gamma Hydroxybutyric Acid is combined with Pizotifen.Approved, Illicit
GepironeThe risk or severity of adverse effects can be increased when Gepirone is combined with Pizotifen.Investigational
GlutethimideThe risk or severity of adverse effects can be increased when Glutethimide is combined with Pizotifen.Approved, Illicit
GuanfacineThe risk or severity of adverse effects can be increased when Guanfacine is combined with Pizotifen.Approved, Investigational
HalazepamThe risk or severity of adverse effects can be increased when Halazepam is combined with Pizotifen.Approved, Illicit, Withdrawn
HaloperidolThe risk or severity of adverse effects can be increased when Haloperidol is combined with Pizotifen.Approved
HalothaneThe risk or severity of adverse effects can be increased when Halothane is combined with Pizotifen.Approved, Vet Approved
HarmalineHarmaline may increase the anticholinergic activities of Pizotifen.Experimental
HeroinThe risk or severity of adverse effects can be increased when Heroin is combined with Pizotifen.Approved, Illicit
HexobarbitalThe risk or severity of adverse effects can be increased when Hexobarbital is combined with Pizotifen.Approved
HydracarbazineHydracarbazine may increase the anticholinergic activities of Pizotifen.Experimental
HydrocodonePizotifen may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.Approved, Illicit
HydromorphoneThe risk or severity of adverse effects can be increased when Hydromorphone is combined with Pizotifen.Approved, Illicit
HydroxyzineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.Approved
IloperidoneThe risk or severity of adverse effects can be increased when Iloperidone is combined with Pizotifen.Approved
ImipramineThe risk or severity of adverse effects can be increased when Imipramine is combined with Pizotifen.Approved
IndalpineThe risk or severity of adverse effects can be increased when Pizotifen is combined with Indalpine.Investigational, Withdrawn
IndiplonThe risk or severity of adverse effects can be increased when Indiplon is combined with Pizotifen.Investigational
IproclozideIproclozide may increase the anticholinergic activities of Pizotifen.Withdrawn
IproniazidIproniazid may increase the anticholinergic activities of Pizotifen.Withdrawn
IsocarboxazidIsocarboxazid may increase the anticholinergic activities of Pizotifen.Approved
IsofluraneThe risk or severity of adverse effects can be increased when Isoflurane is combined with Pizotifen.Approved, Vet Approved
KetamineThe risk or severity of adverse effects can be increased when Ketamine is combined with Pizotifen.Approved, Vet Approved
KetazolamThe risk or severity of adverse effects can be increased when Ketazolam is combined with Pizotifen.Approved
KetobemidoneThe risk or severity of adverse effects can be increased when Ketobemidone is combined with Pizotifen.Approved
LamotrigineThe risk or severity of adverse effects can be increased when Lamotrigine is combined with Pizotifen.Approved, Investigational
LevetiracetamThe risk or severity of adverse effects can be increased when Levetiracetam is combined with Pizotifen.Approved, Investigational
LevobupivacaineThe risk or severity of adverse effects can be increased when Levobupivacaine is combined with Pizotifen.Approved
LevocabastineThe risk or severity of adverse effects can be increased when Pizotifen is combined with Levocabastine.Approved
LevocetirizineThe risk or severity of adverse effects can be increased when Pizotifen is combined with Levocetirizine.Approved
LevodopaThe risk or severity of adverse effects can be increased when Levodopa is combined with Pizotifen.Approved
Levomethadyl AcetateThe risk or severity of adverse effects can be increased when Levomethadyl Acetate is combined with Pizotifen.Approved
LevomilnacipranThe risk or severity of adverse effects can be increased when Pizotifen is combined with Levomilnacipran.Approved
LevorphanolThe risk or severity of adverse effects can be increased when Levorphanol is combined with Pizotifen.Approved
LidocaineThe risk or severity of adverse effects can be increased when Lidocaine is combined with Pizotifen.Approved, Vet Approved
LithiumThe risk or severity of adverse effects can be increased when Lithium is combined with Pizotifen.Approved
LofentanilThe risk or severity of adverse effects can be increased when Lofentanil is combined with Pizotifen.Illicit
LoprazolamThe risk or severity of adverse effects can be increased when Loprazolam is combined with Pizotifen.Experimental
LoratadineThe risk or severity of adverse effects can be increased when Loratadine is combined with Pizotifen.Approved
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Pizotifen.Approved
LormetazepamThe risk or severity of adverse effects can be increased when Lormetazepam is combined with Pizotifen.Approved
LoxapineThe risk or severity of adverse effects can be increased when Loxapine is combined with Pizotifen.Approved
LurasidoneThe risk or severity of adverse effects can be increased when Lurasidone is combined with Pizotifen.Approved
Magnesium SulfateMagnesium Sulfate may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.Approved, Vet Approved
MaprotilineThe risk or severity of adverse effects can be increased when Maprotiline is combined with Pizotifen.Approved
MebanazineMebanazine may increase the anticholinergic activities of Pizotifen.Withdrawn
MebicarThe risk or severity of adverse effects can be increased when Mebicar is combined with Pizotifen.Experimental
MeclizineThe risk or severity of adverse effects can be increased when Meclizine is combined with Pizotifen.Approved
MedazepamThe risk or severity of adverse effects can be increased when Medazepam is combined with Pizotifen.Experimental
MedetomidineThe risk or severity of adverse effects can be increased when Medetomidine is combined with Pizotifen.Vet Approved
MelatoninThe risk or severity of adverse effects can be increased when Melatonin is combined with Pizotifen.Approved, Nutraceutical, Vet Approved
MelperoneThe risk or severity of adverse effects can be increased when Melperone is combined with Pizotifen.Approved
MepivacaineThe risk or severity of adverse effects can be increased when Mepivacaine is combined with Pizotifen.Approved, Vet Approved
MeprobamateThe risk or severity of adverse effects can be increased when Meprobamate is combined with Pizotifen.Approved, Illicit
MeptazinolThe risk or severity of adverse effects can be increased when Meptazinol is combined with Pizotifen.Experimental
MesoridazineThe risk or severity of adverse effects can be increased when Mesoridazine is combined with Pizotifen.Approved
MetaxaloneThe risk or severity of adverse effects can be increased when Metaxalone is combined with Pizotifen.Approved
MethadoneThe risk or severity of adverse effects can be increased when Methadone is combined with Pizotifen.Approved
Methadyl AcetateThe risk or severity of adverse effects can be increased when Methadyl Acetate is combined with Pizotifen.Approved, Illicit
MethapyrileneThe risk or severity of adverse effects can be increased when Methapyrilene is combined with Pizotifen.Withdrawn
MethaqualoneThe risk or severity of adverse effects can be increased when Methaqualone is combined with Pizotifen.Illicit, Withdrawn
MethocarbamolThe risk or severity of adverse effects can be increased when Methocarbamol is combined with Pizotifen.Approved, Vet Approved
MethohexitalThe risk or severity of adverse effects can be increased when Methohexital is combined with Pizotifen.Approved
MethotrimeprazinePizotifen may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.Approved
MethoxyfluraneThe risk or severity of adverse effects can be increased when Methoxyflurane is combined with Pizotifen.Approved, Vet Approved
MethsuximideThe risk or severity of adverse effects can be increased when Methsuximide is combined with Pizotifen.Approved
MethylecgonineThe risk or severity of adverse effects can be increased when Methylecgonine is combined with Pizotifen.Experimental
Methylene blueMethylene blue may increase the anticholinergic activities of Pizotifen.Investigational
MethylphenobarbitalThe risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Pizotifen.Approved
MetyrosinePizotifen may increase the sedative activities of Metyrosine.Approved
MidazolamThe risk or severity of adverse effects can be increased when Midazolam is combined with Pizotifen.Approved, Illicit
MilnacipranThe risk or severity of adverse effects can be increased when Pizotifen is combined with Milnacipran.Approved
MinaprineMinaprine may increase the anticholinergic activities of Pizotifen.Approved
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.Approved, Investigational
MirtazapinePizotifen may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.Approved
MoclobemideMoclobemide may increase the anticholinergic activities of Pizotifen.Approved
MolindoneThe risk or severity of adverse effects can be increased when Molindone is combined with Pizotifen.Approved
MorphineThe risk or severity of adverse effects can be increased when Morphine is combined with Pizotifen.Approved, Investigational
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.Approved, Investigational
NalbuphineThe risk or severity of adverse effects can be increased when Nalbuphine is combined with Pizotifen.Approved
NefazodoneThe risk or severity of adverse effects can be increased when Pizotifen is combined with Nefazodone.Approved, Withdrawn
NialamideNialamide may increase the anticholinergic activities of Pizotifen.Withdrawn
NitrazepamThe risk or severity of adverse effects can be increased when Nitrazepam is combined with Pizotifen.Approved
Nitrous oxideThe risk or severity of adverse effects can be increased when Nitrous oxide is combined with Pizotifen.Approved, Vet Approved
NorfluraneThe risk or severity of adverse effects can be increased when Norflurane is combined with Pizotifen.Investigational
NormethadoneThe risk or severity of adverse effects can be increased when Normethadone is combined with Pizotifen.Approved, Illicit
NortriptylineThe risk or severity of adverse effects can be increased when Nortriptyline is combined with Pizotifen.Approved
OctamoxinOctamoxin may increase the anticholinergic activities of Pizotifen.Withdrawn
OlanzapineThe risk or severity of adverse effects can be increased when Olanzapine is combined with Pizotifen.Approved, Investigational
OlopatadineThe risk or severity of adverse effects can be increased when Olopatadine is combined with Pizotifen.Approved
OndansetronThe risk or severity of adverse effects can be increased when Ondansetron is combined with Pizotifen.Approved
OpiumThe risk or severity of adverse effects can be increased when Opium is combined with Pizotifen.Approved, Illicit
OrphenadrinePizotifen may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.Approved
OsanetantThe risk or severity of adverse effects can be increased when Osanetant is combined with Pizotifen.Investigational
OxazepamThe risk or severity of adverse effects can be increased when Oxazepam is combined with Pizotifen.Approved
OxethazaineThe risk or severity of adverse effects can be increased when Oxethazaine is combined with Pizotifen.Investigational
OxprenololThe risk or severity of adverse effects can be increased when Oxprenolol is combined with Pizotifen.Approved
OxybuprocaineThe risk or severity of adverse effects can be increased when Oxybuprocaine is combined with Pizotifen.Approved
OxycodoneThe risk or severity of adverse effects can be increased when Oxycodone is combined with Pizotifen.Approved, Illicit, Investigational
OxymorphoneThe risk or severity of adverse effects can be increased when Oxymorphone is combined with Pizotifen.Approved, Investigational, Vet Approved
PaliperidoneThe risk or severity of adverse effects can be increased when Paliperidone is combined with Pizotifen.Approved
ParaldehydePizotifen may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.Approved
PargylinePargyline may increase the anticholinergic activities of Pizotifen.Approved
ParoxetineThe risk or severity of adverse effects can be increased when Pizotifen is combined with Paroxetine.Approved, Investigational
PenfluridolThe risk or severity of adverse effects can be increased when Penfluridol is combined with Pizotifen.Experimental
PentazocineThe risk or severity of adverse effects can be increased when Pentazocine is combined with Pizotifen.Approved, Vet Approved
PentobarbitalThe risk or severity of adverse effects can be increased when Pentobarbital is combined with Pizotifen.Approved, Vet Approved
PerampanelPerampanel may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.Approved
PerazineThe risk or severity of adverse effects can be increased when Perazine is combined with Pizotifen.Investigational
PerospironeThe risk or severity of adverse effects can be increased when Perospirone is combined with Pizotifen.Approved
PerphenazineThe risk or severity of adverse effects can be increased when Perphenazine is combined with Pizotifen.Approved
PethidineThe risk or severity of adverse effects can be increased when Pethidine is combined with Pizotifen.Approved
PhenazocineThe risk or severity of adverse effects can be increased when Phenazocine is combined with Pizotifen.Experimental
PhenelzinePhenelzine may increase the anticholinergic activities of Pizotifen.Approved
PhenibutThe risk or severity of adverse effects can be increased when Phenibut is combined with Pizotifen.Experimental
PheniprazinePheniprazine may increase the anticholinergic activities of Pizotifen.Withdrawn
PhenobarbitalThe risk or severity of adverse effects can be increased when Phenobarbital is combined with Pizotifen.Approved
PhenoperidineThe risk or severity of adverse effects can be increased when Phenoperidine is combined with Pizotifen.Experimental
PhenoxyethanolThe risk or severity of adverse effects can be increased when Phenoxyethanol is combined with Pizotifen.Approved
PhenoxypropazinePhenoxypropazine may increase the anticholinergic activities of Pizotifen.Withdrawn
PhenytoinThe risk or severity of adverse effects can be increased when Phenytoin is combined with Pizotifen.Approved, Vet Approved
PimozideThe risk or severity of adverse effects can be increased when Pimozide is combined with Pizotifen.Approved
PipamperoneThe risk or severity of adverse effects can be increased when Pipamperone is combined with Pizotifen.Approved
PipotiazineThe risk or severity of adverse effects can be increased when Pipotiazine is combined with Pizotifen.Approved
PiritramideThe risk or severity of adverse effects can be increased when Piritramide is combined with Pizotifen.Investigational
PirlindolePirlindole may increase the anticholinergic activities of Pizotifen.Approved
PivhydrazinePivhydrazine may increase the anticholinergic activities of Pizotifen.Withdrawn
PomalidomideThe risk or severity of adverse effects can be increased when Pizotifen is combined with Pomalidomide.Approved
PramipexolePizotifen may increase the sedative activities of Pramipexole.Approved, Investigational
PramocaineThe risk or severity of adverse effects can be increased when Pramocaine is combined with Pizotifen.Approved
PrazepamThe risk or severity of adverse effects can be increased when Prazepam is combined with Pizotifen.Approved, Illicit
PregabalinThe risk or severity of adverse effects can be increased when Pregabalin is combined with Pizotifen.Approved, Illicit, Investigational
PrilocaineThe risk or severity of adverse effects can be increased when Prilocaine is combined with Pizotifen.Approved
PrimidoneThe risk or severity of adverse effects can be increased when Primidone is combined with Pizotifen.Approved, Vet Approved
ProcaineThe risk or severity of adverse effects can be increased when Procaine is combined with Pizotifen.Approved, Investigational, Vet Approved
ProchlorperazineThe risk or severity of adverse effects can be increased when Prochlorperazine is combined with Pizotifen.Approved, Vet Approved
PromazineThe risk or severity of adverse effects can be increased when Promazine is combined with Pizotifen.Approved, Vet Approved
PromethazineThe risk or severity of adverse effects can be increased when Promethazine is combined with Pizotifen.Approved
PropanididThe risk or severity of adverse effects can be increased when Propanidid is combined with Pizotifen.Experimental
ProparacaineThe risk or severity of adverse effects can be increased when Proparacaine is combined with Pizotifen.Approved, Vet Approved
PropofolThe risk or severity of adverse effects can be increased when Propofol is combined with Pizotifen.Approved, Investigational, Vet Approved
PropoxycaineThe risk or severity of adverse effects can be increased when Propoxycaine is combined with Pizotifen.Approved
ProtriptylineThe risk or severity of adverse effects can be increased when Protriptyline is combined with Pizotifen.Approved
ProxibarbalThe risk or severity of adverse effects can be increased when Proxibarbal is combined with Pizotifen.Experimental
PSD502The risk or severity of adverse effects can be increased when PSD502 is combined with Pizotifen.Investigational
QuazepamThe risk or severity of adverse effects can be increased when Quazepam is combined with Pizotifen.Approved, Illicit
QuetiapineThe risk or severity of adverse effects can be increased when Quetiapine is combined with Pizotifen.Approved
QuinisocaineThe risk or severity of adverse effects can be increased when Quinisocaine is combined with Pizotifen.Experimental
RacloprideThe risk or severity of adverse effects can be increased when Raclopride is combined with Pizotifen.Investigational
RamelteonThe risk or severity of adverse effects can be increased when Ramelteon is combined with Pizotifen.Approved, Investigational
RasagilineRasagiline may increase the anticholinergic activities of Pizotifen.Approved
RemifentanilThe risk or severity of adverse effects can be increased when Remifentanil is combined with Pizotifen.Approved
RemoxiprideThe risk or severity of adverse effects can be increased when Remoxipride is combined with Pizotifen.Approved, Withdrawn
ReserpineThe risk or severity of adverse effects can be increased when Reserpine is combined with Pizotifen.Approved
RisperidoneThe risk or severity of adverse effects can be increased when Risperidone is combined with Pizotifen.Approved, Investigational
RitanserinThe risk or severity of adverse effects can be increased when Ritanserin is combined with Pizotifen.Investigational
RomifidineThe risk or severity of adverse effects can be increased when Romifidine is combined with Pizotifen.Vet Approved
RopinirolePizotifen may increase the sedative activities of Ropinirole.Approved, Investigational
RopivacaineThe risk or severity of adverse effects can be increased when Ropivacaine is combined with Pizotifen.Approved
RotigotinePizotifen may increase the sedative activities of Rotigotine.Approved
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Pizotifen.Approved
SafrazineSafrazine may increase the anticholinergic activities of Pizotifen.Withdrawn
ScopolamineThe risk or severity of adverse effects can be increased when Scopolamine is combined with Pizotifen.Approved
SecobarbitalThe risk or severity of adverse effects can be increased when Secobarbital is combined with Pizotifen.Approved, Vet Approved
SelegilineSelegiline may increase the anticholinergic activities of Pizotifen.Approved, Investigational, Vet Approved
SepranoloneThe risk or severity of adverse effects can be increased when Sepranolone is combined with Pizotifen.Investigational
SertindoleThe risk or severity of adverse effects can be increased when Sertindole is combined with Pizotifen.Approved, Withdrawn
SertralineThe risk or severity of adverse effects can be increased when Pizotifen is combined with Sertraline.Approved
SevofluraneThe risk or severity of adverse effects can be increased when Sevoflurane is combined with Pizotifen.Approved, Vet Approved
Sodium oxybateSodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.Approved
StiripentolThe risk or severity of adverse effects can be increased when Pizotifen is combined with Stiripentol.Approved
SufentanilThe risk or severity of adverse effects can be increased when Sufentanil is combined with Pizotifen.Approved, Investigational
SulpirideThe risk or severity of adverse effects can be increased when Sulpiride is combined with Pizotifen.Approved
SultoprideThe risk or severity of adverse effects can be increased when Sultopride is combined with Pizotifen.Experimental
SuvorexantPizotifen may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.Approved
TandospironeThe risk or severity of adverse effects can be increased when Tandospirone is combined with Pizotifen.Investigational
TapentadolTapentadol may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.Approved
TasimelteonThe risk or severity of adverse effects can be increased when Pizotifen is combined with Tasimelteon.Approved
TemazepamThe risk or severity of adverse effects can be increased when Temazepam is combined with Pizotifen.Approved
TetrabenazineThe risk or severity of adverse effects can be increased when Tetrabenazine is combined with Pizotifen.Approved
TetracaineThe risk or severity of adverse effects can be increased when Tetracaine is combined with Pizotifen.Approved, Vet Approved
TetrahydropalmatineThe risk or severity of adverse effects can be increased when Tetrahydropalmatine is combined with Pizotifen.Investigational
TetrodotoxinThe risk or severity of adverse effects can be increased when Tetrodotoxin is combined with Pizotifen.Investigational
ThalidomidePizotifen may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.Approved, Investigational, Withdrawn
ThiamylalThe risk or severity of adverse effects can be increased when Thiamylal is combined with Pizotifen.Approved, Vet Approved
ThiopentalThe risk or severity of adverse effects can be increased when Thiopental is combined with Pizotifen.Approved, Vet Approved
ThioridazineThe risk or severity of adverse effects can be increased when Thioridazine is combined with Pizotifen.Withdrawn
ThiothixeneThe risk or severity of adverse effects can be increased when Thiothixene is combined with Pizotifen.Approved
TiagabineThe risk or severity of adverse effects can be increased when Tiagabine is combined with Pizotifen.Approved
TiaprideThe risk or severity of adverse effects can be increased when Tiapride is combined with Pizotifen.Approved, Investigational
TiletamineThe risk or severity of adverse effects can be increased when Tiletamine is combined with Pizotifen.Vet Approved
TilidineThe risk or severity of adverse effects can be increased when Tilidine is combined with Pizotifen.Experimental
TizanidineThe risk or severity of adverse effects can be increased when Tizanidine is combined with Pizotifen.Approved
TolcaponeThe risk or severity of adverse effects can be increased when Tolcapone is combined with Pizotifen.Approved, Withdrawn
ToloxatoneToloxatone may increase the anticholinergic activities of Pizotifen.Approved
TopiramateThe risk or severity of adverse effects can be increased when Topiramate is combined with Pizotifen.Approved
TramadolThe risk or severity of adverse effects can be increased when Tramadol is combined with Pizotifen.Approved, Investigational
Trans-2-PhenylcyclopropylamineTrans-2-Phenylcyclopropylamine may increase the anticholinergic activities of Pizotifen.Experimental
TranylcypromineTranylcypromine may increase the anticholinergic activities of Pizotifen.Approved
TrazodoneThe risk or severity of adverse effects can be increased when Trazodone is combined with Pizotifen.Approved, Investigational
TriazolamThe risk or severity of adverse effects can be increased when Triazolam is combined with Pizotifen.Approved
Tricaine methanesulfonateThe risk or severity of adverse effects can be increased when Tricaine methanesulfonate is combined with Pizotifen.Vet Approved
TrichloroethyleneThe risk or severity of adverse effects can be increased when Trichloroethylene is combined with Pizotifen.Experimental
TrifluoperazineThe risk or severity of adverse effects can be increased when Trifluoperazine is combined with Pizotifen.Approved
TrifluperidolThe risk or severity of adverse effects can be increased when Trifluperidol is combined with Pizotifen.Experimental
TriflupromazineThe risk or severity of adverse effects can be increased when Triflupromazine is combined with Pizotifen.Approved, Vet Approved
TrimipramineThe risk or severity of adverse effects can be increased when Trimipramine is combined with Pizotifen.Approved
TriprolidineThe risk or severity of adverse effects can be increased when Triprolidine is combined with Pizotifen.Approved
Valproic AcidThe risk or severity of adverse effects can be increased when Valproic Acid is combined with Pizotifen.Approved, Investigational
VenlafaxineThe risk or severity of adverse effects can be increased when Pizotifen is combined with Venlafaxine.Approved
VeraliprideThe risk or severity of adverse effects can be increased when Veralipride is combined with Pizotifen.Experimental
VigabatrinThe risk or severity of adverse effects can be increased when Vigabatrin is combined with Pizotifen.Approved
Vinyl etherThe risk or severity of adverse effects can be increased when Vinyl ether is combined with Pizotifen.Experimental
VortioxetineThe risk or severity of adverse effects can be increased when Vortioxetine is combined with Pizotifen.Approved
XenonThe risk or severity of adverse effects can be increased when Xenon is combined with Pizotifen.Experimental
XylazineThe risk or severity of adverse effects can be increased when Xylazine is combined with Pizotifen.Vet Approved
ZaleplonThe risk or severity of adverse effects can be increased when Zaleplon is combined with Pizotifen.Approved, Illicit, Investigational
ZiconotideThe risk or severity of adverse effects can be increased when Pizotifen is combined with Ziconotide.Approved
ZimelidineThe risk or severity of adverse effects can be increased when Pizotifen is combined with Zimelidine.Withdrawn
ZiprasidoneThe risk or severity of adverse effects can be increased when Ziprasidone is combined with Pizotifen.Approved
ZolazepamThe risk or severity of adverse effects can be increased when Zolazepam is combined with Pizotifen.Vet Approved
ZolpidemPizotifen may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.Approved
ZonisamideThe risk or severity of adverse effects can be increased when Zonisamide is combined with Pizotifen.Approved, Investigational
ZopicloneThe risk or severity of adverse effects can be increased when Zopiclone is combined with Pizotifen.Approved
ZotepineThe risk or severity of adverse effects can be increased when Zotepine is combined with Pizotifen.Approved
ZuclopenthixolThe risk or severity of adverse effects can be increased when Zuclopenthixol is combined with Pizotifen.Approved, Investigational
Food Interactions
  • Take without regard to meals.

References

General References
Not Available
External Links
ChemSpider
25497
BindingDB
82088
ChEBI
50212
ChEMBL
CHEMBL294951
ATC Codes
N02CX01 — Pizotifen
AHFS Codes
  • 28:32.92 — Antimigraine Agents, Miscellaneous

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
TabletOral0.50 mg
TabletOral1 mg
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.00706 mg/mLALOGPS
logP4.7ALOGPS
logP4.49ChemAxon
logS-4.6ALOGPS
pKa (Strongest Basic)7.98ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area3.24 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity101.1 m3·mol-1ChemAxon
Polarizability34.36 Å3ChemAxon
Number of Rings4ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as cycloheptathiophenes. These are polycyclic compounds containing a thiophene ring fused to a 7 member carbocyclic moiety. Thiophene is 5-membered ring consisting of four carbon atoms and one sulfur atom.
Kingdom
Organic compounds
Super Class
Organoheterocyclic compounds
Class
Cycloheptathiophenes
Sub Class
Not Available
Direct Parent
Cycloheptathiophenes
Alternative Parents
Piperidines / Benzenoids / Thiophenes / Heteroaromatic compounds / Trialkylamines / Azacyclic compounds / Organopnictogen compounds / Hydrocarbon derivatives
Substituents
Cycloheptathiophene / Benzenoid / Piperidine / Heteroaromatic compound / Thiophene / Tertiary aliphatic amine / Tertiary amine / Azacycle / Organic nitrogen compound / Organopnictogen compound
Molecular Framework
Aromatic heteropolycyclic compounds
External Descriptors
benzocycloheptathiophene (CHEBI:50212)

Drug created on January 21, 2008 05:21 / Updated on October 21, 2017 09:34