Showing BioInteractions for Amisulpride (DB06288)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 4

	Interacting Group	Interacting Drugs
	Amisulpride is a Dopamine D2 receptor antagonist
1	Dopamine D2 receptor agonists	Amantadine, Apomorphine, Brexpiprazole, Bromocriptine, Cabergoline, Cariprazine, Dihydro-alpha-ergocryptine, Dopamine, Ergotamine, Ketamine, Lamotrigine, Levodopa, Lisuride, Memantine, Minaprine, Pergolide, Pramipexole, Quinagolide, Ropinirole, Rotigotine
2	Dopamine D2 receptor antagonists	Acepromazine, Acetophenazine, Alizapride, Amoxapine, Aripiprazole, AS-8112, Asenapine, Blonanserin, Bromopride, Buspirone, Carphenazine, Chlorpromazine, Chlorprothixene, Clozapine, Domperidone, Droperidol, Etoperidone, Flupentixol, Fluphenazine, Fluspirilene, Haloperidol, Iloperidone, JNJ-37822681, Loxapine, Lurasidone, Melperone, Memantine, Mesoridazine, Methotrimeprazine, Metoclopramide, Mianserin, Molindone, Nortriptyline, Olanzapine, Paliperidone, Perospirone, Perphenazine, Pimozide, Pipamperone, Pipotiazine, Prochlorperazine, Promazine, Promethazine, Propiomazine, Quetiapine, Raclopride, Remoxipride, Risperidone, Sertindole, Sulpiride, Tetrahydropalmatine, Thiethylperazine, Thioproperazine, Thioridazine, Thiothixene, Trifluoperazine, Triflupromazine, YKP-1358, Yohimbine, Ziprasidone, Zotepine, Zuclopenthixol
3	Dopamine D2 receptor partial agonists	Aripiprazole, Aripiprazole lauroxil, Brexpiprazole, Cariprazine, Ketamine, Lumateperone, Sarizotan
4	Dopamine D2 receptor inhibitors	Escitalopram, Lamotrigine, Tetrabenazine
5	Dopamine D2 receptor binders	Amphetamine, Desipramine, Imipramine, Maprotiline
6	Dopamine D2 receptor blockers	Tiapride

	Interacting Group	Interacting Drugs
	Amisulpride is a Dopamine D3 receptor antagonist
1	Dopamine D3 receptor antagonists	Amoxapine, Aripiprazole, AS-8112, Asenapine, Blonanserin, Buspirone, Chlorprothixene, Clozapine, Domperidone, Flupentixol, Iloperidone, Methotrimeprazine, Olanzapine, Paliperidone, Pimozide, Remoxipride, Sulpiride, Yohimbine, Ziprasidone
2	Dopamine D3 receptor agonists	Apomorphine, Bromocriptine, Cabergoline, Captodiame, Cariprazine, Dopamine, Levodopa, Lisuride, Pergolide, Pramipexole, Ropinirole, Rotigotine, Tianeptine
3	Dopamine D3 receptor partial agonists	Aripiprazole, Cariprazine, Dihydro-alpha-ergocryptine
4	Dopamine D3 receptor inverse agonists	Haloperidol
5	Dopamine D3 receptor ligands	Quetiapine, Sarizotan
6	Dopamine D3 receptor inhibitors	Chlorpromazine
7	Dopamine D3 receptor binders	Loxapine, Mianserin
8	Dopamine D3 receptor blockers	Tiapride

	Interacting Group	Interacting Drugs
	Amisulpride is a 5-hydroxytryptamine receptor 7 antagonist
1	5-hydroxytryptamine receptor 7 antagonists	Amitriptyline, Amoxapine, Aripiprazole, Asenapine, Bromocriptine, Cabergoline, Clozapine, Cyclobenzaprine, Epinastine, Iloperidone, Imipramine, Lurasidone, Maprotiline, Methysergide, Mianserin, Risperidone, SB-269970, Vortioxetine, Ziprasidone, Zotepine
2	5-hydroxytryptamine receptor 7 partial agonists	Aripiprazole
3	5-hydroxytryptamine receptor 7 ligands	Quetiapine
4	5-hydroxytryptamine receptor 7 binders	Chlorpromazine, Dopamine, Loxapine
5	5-hydroxytryptamine receptor 7 agonists	Lofexidine, Zolmitriptan

	Interacting Group	Interacting Drugs
	Amisulpride is a 5-hydroxytryptamine receptor 2A antagonist
1	5-hydroxytryptamine receptor 2A antagonists	Acepromazine, Amitriptyline, Amoxapine, Amperozide, Aripiprazole, Aripiprazole lauroxil, Asenapine, Blonanserin, Brexpiprazole, Butriptyline, Cariprazine, Chlorpromazine, Chlorprothixene, Cinitapride, Clomipramine, Clozapine, Cyclobenzaprine, Cyproheptadine, Deramciclane, Desipramine, Dosulepin, Doxepin, Epinastine, Etoperidone, Flibanserin, Flupentixol, Fluspirilene, Iloperidone, Imipramine, Lorpiprazole, Loxapine, Lumateperone, Lurasidone, Mesoridazine, Methotrimeprazine, Methysergide, Mianserin, Minaprine, Mirtazapine, Molindone, Nefazodone, Nortriptyline, Olanzapine, Paliperidone, Pipotiazine, Pizotifen, Promazine, Propiomazine, Quetiapine, Risperidone, Sertindole, Tegaserod, Thioridazine, Thiothixene, Trazodone, Yohimbine, Ziprasidone, Zotepine, Zuclopenthixol
2	5-hydroxytryptamine receptor 2A partial agonists	4-Bromo-2,5-dimethoxyphenethylamine, Aripiprazole
3	5-hydroxytryptamine receptor 2A agonists	2,5-Dimethoxy-4-ethylthioamphetamine, 5-methoxy-N,N-dimethyltryptamine, Apomorphine, Bromocriptine, Cabergoline, Cannabidiol, Cisapride, Ergotamine, Fenfluramine, Lisuride, Midomafetamine, MMDA, N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine, Paroxetine, Pergolide, Pipamperone, Trimipramine, Zolmitriptan
4	5-hydroxytryptamine receptor 2A inducers	Donepezil
5	5-hydroxytryptamine receptor 2A inverse agonists	Ketanserin, Perospirone, Pimavanserin, Ritanserin, Sarpogrelate
6	5-hydroxytryptamine receptor 2A binders	Maprotiline
7	5-hydroxytryptamine receptor 2A inhibitors	Escitalopram, Lamotrigine