Showing BioInteractions for Human C1-esterase inhibitor (DB06404)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Human C1-esterase inhibitor is a Complement C1r subcomponent inhibitor | ||
| 1 | Complement C1r subcomponent inhibitors | Conestat alfa, Gabexate |
| 2 | Complement C1r subcomponent modulators | Zinc chloride, Zinc sulfate, unspecified form |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Human C1-esterase inhibitor is a Complement C1s subcomponent inhibitor | ||
| 1 | Complement C1s subcomponent inhibitors | Conestat alfa, Gabexate |
| 2 | Complement C1s subcomponent modulators | Zinc chloride, Zinc sulfate, unspecified form |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Human C1-esterase inhibitor is a Plasma kallikrein inhibitor | ||
| 1 | Plasma kallikrein inhibitors | Berotralstat, Conestat alfa, Ecallantide, Gabexate, Lanadelumab, Zinc chloride, Zinc sulfate, unspecified form |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Human C1-esterase inhibitor is a Coagulation factor XII inhibitor | ||
| 1 | Coagulation factor XII activators | Ethanolamine oleate |
| 2 | Coagulation factor XII inhibitors | Conestat alfa, Nafamostat |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Human C1-esterase inhibitor is a Prothrombin inhibitor | ||
| 1 | Prothrombin inhibitors | Antithrombin Alfa, Argatroban, Betrixaban, Bivalirudin, Conestat alfa, Dabigatran etexilate, Enoxaparin, Gabexate, Lepirudin, Nafamostat, Suramin, Thrombomodulin Alfa, Ximelagatran |
| 2 | Prothrombin activators | Antihemophilic factor, human recombinant, Lonoctocog alfa, Menadione, Moroctocog alfa |
| 3 | Prothrombin agonists | Anti-inhibitor coagulant complex, Kappadione |
| 4 | Prothrombin substrates | Anti-inhibitor coagulant complex |
| 5 | Prothrombin binders | Turoctocog alfa, Turoctocog alfa pegol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Human C1-esterase inhibitor is a Coagulation factor XI inhibitor | ||
| 1 | Coagulation factor XI ligands | Coagulation Factor IX (Recombinant), Coagulation Factor IX Human |
| 2 | Coagulation factor XI inhibitors | Conestat alfa |
| 3 | Coagulation factor XI activators | Human thrombin, Thrombin, Zinc chloride, Zinc sulfate, unspecified form |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Human C1-esterase inhibitor is a Tissue-type plasminogen activator inhibitor | ||
| 1 | Tissue-type plasminogen activator antagonists | Aminocaproic acid |
| 2 | Tissue-type plasminogen activator inhibitors | Conestat alfa |
| 3 | Tissue-type plasminogen activator modulators | Dexibuprofen |