Showing BioInteractions for Zaltoprofen (DB06737)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Zaltoprofen is a UDP-glucuronosyltransferase 2B7 substrate
1UDP-glucuronosyltransferase 2B7 substratesAcemetacin, Ambrisentan, Artenimol, Atorvastatin, Carbamazepine, Codeine, Dapagliflozin, Diclofenac, Enasidenib, Epirubicin, Ertugliflozin, Etodolac, Ezetimibe, Flurbiprofen, Fluvastatin, Ibuprofen, Indomethacin, Losartan, Lovastatin, Mitiglinide, Morphine, Mycophenolate mofetil, Mycophenolic acid, Nalmefene, Naproxen, Oxazepam, Pitavastatin, Silodosin, Simvastatin, Suprofen, Tapentadol, Troglitazone, Vadimezan, Valproic Acid, Zidovudine
2UDP-glucuronosyltransferase 2B7 inhibitorsChenodeoxycholic acid, Dovitinib, Flunitrazepam, Indomethacin, Ketoconazole
Interacting GroupInteracting Drugs
Zaltoprofen is a Cytochrome P450 2C9 substrate
1Cytochrome P450 2C9 inhibitorsAbiraterone, Acetyl sulfisoxazole, Agomelatine, Amiodarone, Amlodipine, Amodiaquine, Anastrozole, Armodafinil, Atorvastatin, Atovaquone, Avasimibe, Azelastine, Belinostat, Benzbromarone, Bicalutamide, Bortezomib, Candesartan, Capecitabine, Ceritinib, Cerivastatin, Cimetidine, Cimicifuga racemosa, Cisplatin, Clevidipine, Clopidogrel, Clotrimazole, Crisaborole, Curcumin, Cyclizine, Cyclosporine, Delavirdine, Diacerein, Diethylstilbestrol, Doconexent, Dosulepin, Efavirenz, Enasidenib, Epinephrine, Estrone sulfate, Ethanol, Etoricoxib, Etravirine, Felbamate, Felodipine, Fenofibrate, Flecainide, Floxuridine, Fluconazole, Fluorouracil, Fluoxetine, Fluvastatin, Fluvoxamine, Gefitinib, Gemfibrozil, Genistein, Ginkgo biloba, Glyburide, Imatinib, Iproniazid, Isavuconazole, Isoniazid, Ketoconazole, Ketoprofen, Lansoprazole, Leflunomide, Lenvatinib, Lifitegrast, Lobeglitazone, Lopinavir, Lovastatin, Lumacaftor, Manidipine, Medical Cannabis, Medroxyprogesterone acetate, Methimazole, Metronidazole, Miconazole, Midostaurin, Mifepristone, Modafinil, Nabilone, Nilotinib, Noscapine, Oritavancin, Parecoxib, Paroxetine, Phenylbutazone, Phenytoin, Piperine, Pranlukast, Promethazine, Quinidine, Rabeprazole, Regorafenib, Rhein, Rucaparib, Safinamide, Sertraline, Sildenafil, Simvastatin, Sitaxentan, Sorafenib, Stiripentol, Sulconazole, Sulfadiazine, Sulfadimethoxine, Sulfamethizole, Sulfamethoxazole, Sulfamoxole, Sulfaphenazole, Sulfapyridine, Sulfinpyrazone, Sulfisoxazole, Suprofen, Tamoxifen, Teniposide, Ticagrelor, Ticlopidine, Tolcapone, Topiroxostat, Tranylcypromine, Troglitazone, Valdecoxib, Valproic Acid, Valsartan, Vemurafenib, Verapamil, Vismodegib, Voriconazole, Zafirlukast, Zucapsaicin
2Cytochrome P450 2C9 substrates(R)-warfarin, (S)-Warfarin, Aceclofenac, Acenocoumarol, Acetaminophen, Acetohexamide, Acetylsalicylic acid, Alosetron, Alprazolam, Aminophenazone, Amitriptyline, Amprenavir, Antipyrine, Apixaban, Arachidonic Acid, Arformoterol, Artemether, Asunaprevir, Atazanavir, Azelastine, Bexarotene, Bioallethrin, Bortezomib, Bosentan, Brivaracetam, Buprenorphine, Bupropion, Cabozantinib, Caffeine, Candesartan, Candesartan cilexetil, Cannabidiol, Carbutamide, Carvedilol, Celecoxib, Chlorpropamide, Cinnarizine, Cisapride, Clopidogrel, Clozapine, Cyclophosphamide, Dapagliflozin, Dapsone, Dextromethorphan, Diazepam, Diclofenac, Dicoumarol, Diphenhydramine, Doconexent, Dolasetron, Donepezil, Dorzolamide, Doxepin, Dronabinol, Eletriptan, Enasidenib, Enzalutamide, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Estrone sulfate, Eszopiclone, Etodolac, Etoricoxib, Etravirine, Fluindione, Flunarizine, Flunitrazepam, Fluoxetine, Flurbiprofen, Fluvastatin, Formoterol, Fosphenytoin, Glibornuride, Gliclazide, Glimepiride, Glipizide, Gliquidone, Glisoxepide, Glyburide, Haloperidol, Halothane, Hexobarbital, Histamine, Hydromorphone, Ibuprofen, Idarubicin, Ifosfamide, Imatinib, Indisulam, Indomethacin, Irbesartan, Ixazomib, Ketamine, Ketobemidone, Ketoprofen, Lacosamide, Leflunomide, Lesinurad, Licofelone, Lidocaine, Lornoxicam, Losartan, Lumiracoxib, Lynestrenol, Medical Cannabis, Mefenamic acid, Melatonin, Meloxicam, Mephenytoin, Mestranol, Metahexamide, Methadone, Methoxyflurane, Mirtazapine, Moclobemide, Montelukast, Nabiximols, Naproxen, Nateglinide, Netupitant, Niclosamide, Nicotine, Olodaterol, Omeprazole, Ondansetron, Ospemifene, Paramethadione, Parecoxib, Perphenazine, Phenacetin, Phenobarbital, Phenprocoumon, Phenylbutazone, Phenytoin, Pioglitazone, Piperaquine, Piroxicam, Pitavastatin, Prasugrel, Primidone, Progesterone, Proguanil, Promazine, Propacetamol, Propofol, Quazepam, Quinidine, Quinine, Ramelteon, Rofecoxib, Rosiglitazone, Rosuvastatin, Rupatadine, Salicylic acid, Selegiline, Seratrodast, Sertraline, Sildenafil, Sitaxentan, Sulfamethoxazole, Sulfinpyrazone, Suprofen, Tamoxifen, Tapentadol, Temazepam, Tenoxicam, Terbinafine, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thalidomide, Thiamylal, Tolazamide, Tolbutamide, Tolterodine, Torasemide, Trabectedin, Treprostinil, Tretinoin, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Valdecoxib, Valproic Acid, Valsartan, Venlafaxine, Verapamil, Vicriviroc, Vismodegib, Voriconazole, Vortioxetine, Warfarin, Ximelagatran, Zafirlukast, Zidovudine, Zileuton, Zolpidem, Zopiclone
3Cytochrome P450 2C9 inducersApalutamide, Aprepitant, Avatrombopag, Bosentan, Carbamazepine, Dabrafenib, Dapsone, Delafloxacin, Enzalutamide, Etravirine, Fosaprepitant, Fosphenytoin, Isavuconazole, Ivosidenib, Ketamine, Lansoprazole, Letermovir, Lopinavir, Lumacaftor, Midostaurin, Modafinil, Peginterferon alfa-2b, Phenobarbital, Phenytoin, Primidone, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Ritonavir, Secobarbital, Vigabatrin
Interacting GroupInteracting Drugs
Zaltoprofen is a Prostaglandin G/H synthase 1 substrate
1Prostaglandin G/H synthase 1 inhibitorsAceclofenac, Acetaminophen, Acetylsalicylic acid, Antipyrine, Antrafenine, Balsalazide, Bromfenac, Bufexamac, Carprofen, Choline magnesium trisalicylate, Dexibuprofen, Dexketoprofen, Diclofenac, Diethylcarbamazine, Diflunisal, Dihomo-gamma-linolenic acid, Droxicam, Etodolac, Fenoprofen, Flurbiprofen, Hyperforin, Ibuprofen, Icosapent, Indomethacin, Ketoprofen, Ketorolac, Lornoxicam, Lumiracoxib, Magnesium salicylate, Meclofenamic acid, Mefenamic acid, Meloxicam, Mesalazine, Nabumetone, Naproxen, Nepafenac, Nitroaspirin, Oxaprozin, Phenylbutazone, Piroxicam, Resveratrol, Salicylic acid, Salsalate, Sulfasalazine, Sulindac, Suprofen, Talniflumate, Tenoxicam, Tiaprofenic acid, Tolmetin, Trolamine salicylate
2Prostaglandin G/H synthase 1 inducersDesmopressin, Minoxidil
3Prostaglandin G/H synthase 1 substratesCandesartan, Candesartan cilexetil, Carvedilol, Chlorpropamide, Dapsone, Diazepam, Diclofenac, Diphenhydramine, Dronabinol, Eletriptan, Eszopiclone, Etoposide, Hexobarbital, Hydromorphone, Ifosfamide, Imatinib, Irbesartan, Ketamine, Ketobemidone, Loxoprofen, Montelukast, Nateglinide, Nortriptyline, Pioglitazone, Rofecoxib, Rosiglitazone, Seratrodast, Sulfamethoxazole, Terbinafine, Thalidomide, Torasemide, Trabectedin, Valproic Acid, Voriconazole, Zafirlukast, Zileuton, Zolpidem, Zopiclone
4Prostaglandin G/H synthase 1 antagonistsAcemetacin, Dexketoprofen, Glycol salicylate, Loxoprofen, Menthyl salicylate, Phenyl salicylate, Propacetamol, Talniflumate, Tolfenamic Acid, Triflusal