Sodium cellulose phosphate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Sodium cellulose phosphate
Accession Number
DB06776
Type
Small Molecule
Groups
Approved
Description

Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. 1

This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intestinal calcium absorption.

Synonyms
  • Cellulose dihydrogen phosphate, disodium salt
  • Cellulose disodium phosphate
  • Cellulose sodium phosphate
International/Other Brands
Calcibind (Mission Pharma)
Categories
UNII
E6S1NJ4Y5Q
CAS number
9038-41-9

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action

When it is taken orally, it stays in the intestine and it binds strongly to calcium inhibiting its intestinal absorption. From there, inhibition is caused due to the lower intraluminal calcium levels, which is typically available for absorption.2

TargetActionsOrganism
ACalcium ions
binder
Humans
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
  1. Lake KD, Brown DC: New drug therapy for kidney stones: a review of cellulose sodium phosphate, acetohydroxamic acid, and potassium citrate. Drug Intell Clin Pharm. 1985 Jul-Aug;19(7-8):530-9. [PubMed:3896714]
  2. WikiDoc: Editor-In-Chief: C. Michael Gibson, M.S., M.D. [Link]
External Links
ChEMBL
CHEMBL1201457
Wikipedia
Sodium_cellulose_phosphate
ATC Codes
V03AG01 — Sodium cellulose phosphate

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Targets

Kind
Small molecule
Organism
Humans
Pharmacological action
Yes
Actions
Binder
References
  1. Lake KD, Brown DC: New drug therapy for kidney stones: a review of cellulose sodium phosphate, acetohydroxamic acid, and potassium citrate. Drug Intell Clin Pharm. 1985 Jul-Aug;19(7-8):530-9. [PubMed:3896714]

Drug created on September 14, 2010 10:21 / Updated on June 04, 2019 06:29