Povidone-iodine

Identification

Logo pink
Are you a
new drug developer?
Contact us to learn more about our customized products and solutions.
Logo pink
Stay in the know!
As part of our commitment to providing the most up-to-date drug information, we will be releasing #DrugBankUpdates with our newly added curated drug pages.
#DrugBankUpdates
Name
Povidone-iodine
Accession Number
DB06812
Type
Small Molecule
Groups
Approved
Description

Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in vitro testing to demonstrate anti-bacterial activity it was found that the complex was less toxic in mice than tincture of iodine. Human clinical trials showed the product to be superior to other iodine formulations. Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic.

Synonyms
  • Iodopovidone
  • Povidone iodine
  • PVP-I
Active Moieties
NameKindUNIICASInChI Key
Iodineunknown9679TC07X47553-56-2PNDPGZBMCMUPRI-UHFFFAOYSA-N
PovidoneunknownFZ989GH94E9003-39-8Not applicable
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
BetadineSolution5 mg/1mLOphthalmicALCON LABORATORIES, INC.2000-04-01Not applicableUs
BetadineSolution5 mg/1mLOphthalmicRebel Distributors2000-04-01Not applicableUs
Douche Tray 1%KitTopicalAllegiance Healthcare Corporation1993-12-311999-07-08Canada
Irrigation Tray 10% KitLiquidTopicalBaxter Laboratories1991-12-311999-08-10Canada
Irrigation Tray W Pvp-I Prep Pad 1%LiquidTopicalBaxter Laboratories1992-12-311999-08-10Canada
Urethral Cath Tray W Iodphor Pvp Pad 1%LiquidTopicalBaxter Laboratories1992-12-311999-08-10Canada
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

    Learn more
  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

    Learn more
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
3-in-1 First Aid Povidone-Iodine SwabLiquid10 mg/1mLTopicalSwabplus Inc.2003-03-012013-01-30Us
3M Skin and Nasal AntisepticSolution5 mg/1mLTopical3M Health Care2009-07-01Not applicableUs
4046 First Aid KitKit10 mg/1mLTopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
Acu Dyne OintmentOintmentTopicalAcme United Corporation1977-12-311997-05-30Canada
Acu Dyne Prep Soln LiqLiquidTopicalAcme United Corporation1977-12-311997-05-30Canada
Acu Dyne Skin CleanserLiquidTopicalAcme United Corporation1976-12-311997-05-30Canada
Acu Dyne Swab StickStickTopicalAcme United Corporation1977-12-311997-05-30Canada
Acudyne Prep SolutionSolutionTopicalAcme United Corporation1976-12-311997-05-30Canada
Acudyne Prep Swab F420SwabTopicalAcme United Corporation1973-12-311997-05-30Canada
Alpha OneGel10 mg/1mLTopicalAOSS Medical Supply, Inc.2019-10-24Not applicableUs
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

    Learn more
  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

    Learn more
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
3-Step First Aid KitPovidone-iodine (100 mg/10mL) + Benzalkonium chloride (11 mg/10mL) + Lidocaine hydrochloride (100 mg/10mL)KitTopicalSwabplus Inc.2003-03-01Not applicableUs
4042 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)KitTopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4044 First Aid KitPovidone-iodine (10 mg/1mL) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g)KitTopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4045 First Aid KitPovidone-iodine (10 mg/1mL) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g)KitTopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4050 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)KitTopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4064 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)TopicalHoneywell Safety Products USA, Inc2018-11-212019-10-18Us
4065 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)TopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4066 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)TopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4067 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)TopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4078 First Aid KitPovidone-iodine (10 mg/1mL) + Benzalkonium chloride (0.13 g/100g) + Isopropyl alcohol (0.7 mL/1mL) + Lidocaine hydrochloride (0.5 g/100g)KitTopicalHoneywell Safety Products USA, Inc2018-10-18Not applicableUs
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
4042 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)KitTopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4044 First Aid KitPovidone-iodine (10 mg/1mL) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g)KitTopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4045 First Aid KitPovidone-iodine (10 mg/1mL) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g)KitTopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4046 First Aid KitPovidone-iodine (10 mg/1mL)KitTopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4050 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)KitTopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4064 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)TopicalHoneywell Safety Products USA, Inc2018-11-212019-10-18Us
4065 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)TopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4066 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)TopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4067 First Aid KitPovidone-iodine (10 mg/1mL) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Lidocaine hydrochloride (0.5 g/100g) + Neomycin sulfate (3.5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g)TopicalHoneywell Safety Products USA, Inc2018-11-21Not applicableUs
4078 First Aid KitPovidone-iodine (10 mg/1mL) + Benzalkonium chloride (0.13 g/100g) + Isopropyl alcohol (0.7 mL/1mL) + Lidocaine hydrochloride (0.5 g/100g)KitTopicalHoneywell Safety Products USA, Inc2018-10-18Not applicableUs
Categories
UNII
85H0HZU99M
CAS number
25655-41-8
Weight
Not Available
Chemical Formula
Not Available
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

Pharmacology

Indication

For topical application in the treatment and prevention of infection in wounds.

Associated Conditions
Associated Therapies
Pharmacodynamics

Povidone iodine is a kind of iodine disinfectant which directly cause in vivo protein denaturation, precipitation of bacteria, and further resulting in the death of pathogenic microorganisms. Therefore, it is effective in disinfection and sterilization. It can kill viruses, bacteria, spores, fungi, and protozoa with low toxicity to human. Povidone-iodine aqueous solution has strong pharmacological activity against Staphylococcus aureus, Neisseria gonorrhoeae, Pseudomonas aeruginosa, syphilis, hepatitis B virus, HIV, and Trichomonas vaginalis. Povidone iodine gel is a gynecological topical semi-mobile colloidal agent made by povidone iodine and hydrophilic matrix. It is a system for maintaining its sustained release. Owing to the continuous release of free iodine, it can enable the skin and mucous membranes to maintain a certain effective concentration of iodine for killing bacteria. It is mainly used for gynecological vaginal infection. It exerted its effect through being miscible with vaginal secretions and further killing the inside pathogenic microorganisms, and thus blocking the spread of sexually transmitted diseases and invasion, as well as treating other infected vaginal diseases caused by other kinds of bacteria.

Published reports on the in vitro antimicrobial efficacy of iodophors demonstrate that iodophors are bactericidal, mycobactericidal, and virucidal but can require prolonged contact times to kill certain fungi and bacterial spores. Three brands of povidone-iodine solution have demonstrated more rapid kill (seconds to minutes) of S. aureus and M. chelonae at a 1:100 dilution than did the stock solution. The virucidal activity of 75–150 ppm available iodine was demonstrated against seven viruses. Other investigators have questioned the efficacy of iodophors against poliovirus in the presence of organic matter and rotavirus in distilled or tapwater. Manufacturers' data demonstrate that commercial iodophors are not sporicidal, but they are tuberculocidal, fungicidal, virucidal, and bactericidal at their recommended use-dilution.

Mechanism of action

Povidone-iodine is called iodophore which means povidone acts as a carrier of iodine. Iodine is considered as the active moiety that mediates microbicidal actions. When released from the complex, free iodine (I2) penetrates the cell wall of microorganisms quickly, and the lethal effects are believed to result from disruption of protein and nucleic acid structure and synthesis. While the full mechanism of action is not fully elucidated, iodine is thought to inhibit vital bacterial cellular mechanisms and structures, and oxidizes nucleotides fatty or amino acids in bacterial cell membranes 1. Additionally, free iodine disrupts the function of the cytosolic enzymes involved in the respiratory chain, causing them to become denatured and deactivated 1. In vitro evidence suggests that iodine also counteracts inflammation elicited by both pathogens and the host response via multifactorial effects. In hosts, povidone-iodine was demonstrated to modulate the redox potential, inhibit the release of inflammatory mediators such as TNF-α and β-galactosidase, inhibit metalloproteinase production, and potentiate the healing signals from pro-inflammatory cytokines by activation of monocytes, T-lymphocytes, and macrophages, in vitro 1.

Additional Data Available
Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

Learn more
Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

Learn more
Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

Learn more
Absorption

Povidone-Iodine is intended for topical application and is not absorbed.

Volume of distribution

Povidone-Iodine is intended for topical application and has no volume of distribution.

Protein binding

To be used topical. No plasma protein binding reported.

Metabolism

Povidone-Iodine is not absorbed or metabolized.

Route of elimination

Povidone-Iodine is intended for topical application and is not eliminated.

Half life

Povidone-Iodine is intended for topical application and is not eliminated.

Clearance

Povidone-Iodine is intended for topical application and is not eliminated.

Toxicity

ORAL (LD50): Acute: 8000 mg/kg [Rat]. 8100 mg/kg [Mouse]

Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

References

General References
  1. Bigliardi PL, Alsagoff SAL, El-Kafrawi HY, Pyon JK, Wa CTC, Villa MA: Povidone iodine in wound healing: A review of current concepts and practices. Int J Surg. 2017 Aug;44:260-268. doi: 10.1016/j.ijsu.2017.06.073. Epub 2017 Jun 23. [PubMed:28648795]
  2. The efficacy and risks of using povidone-iodine irrigation to prevent surgical site infection: an evidence-based review [Link]
  3. Iodophore activity, CDC [Link]
External Links
KEGG Drug
D00863
KEGG Compound
C08043
PubChem Substance
347910372
ChEBI
8347
ChEMBL
CHEMBL1201724
Wikipedia
Povidone-iodine
ATC Codes
G01AX11 — Povidone-iodineR02AA15 — Povidone-iodineD08AG02 — Povidone-iodineD09AA09 — Povidone-iodineS01AX18 — Povidone-iodineD11AC06 — Povidone-iodine
AHFS Codes
  • 40:36.00 — Irrigating Solutions
  • 84:04.92 — Miscellaneous Local Anti-infectives
MSDS
Download (47.9 KB)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0CompletedTreatmentChronic Rhinosinusitis (Diagnosis)1
0Not Yet RecruitingPreventionDisinfectant Causing Toxic Effect1
0RecruitingBasic ScienceCleaning Product Causing Toxic Effect1
0RecruitingPreventionAge-Related Macular Degeneration (ARMD) / Diabetic Vascular Diseases / Proliferative Retinopathy / Retina Vein Occlusion1
1RecruitingTreatmentMalignant Pleural Effusions1
1, 2Not Yet RecruitingTreatmentAdenoviral Keratoconjunctivitis1
2CompletedPreventionCatheter Related Infections / Urinary Tract Infection1
2CompletedPreventionOral Mucositis1
2CompletedPreventionPostoperative Infections1
2CompletedTreatmentAcute, Perforated Appendicitis1
2CompletedTreatmentBacterial Keratitis / Childhood Blindness / Infected Corneal Ulcers / Ulcerative keratitis1
2RecruitingPreventionSurgical Site Infections1
2RecruitingSupportive CareBreast Cancer1
2RecruitingTreatmentAcanthamoeba Keratitis1
2TerminatedPreventionSurgical Site Infections1
2Unknown StatusPreventionSurgical Site Infections1
2, 3CompletedBasic ScienceCesarean Section; Infection / Surgical Site Infections1
3CompletedNot AvailableHealthy Volunteers1
3CompletedPreventionCariostatic Agents / Dental Decay1
3CompletedPreventionInfection NOS1
3CompletedPreventionInfection Secondary to Surgical Procedure1
3CompletedPreventionInfectious Diseases1
3CompletedPreventionPostoperative Infections1
3CompletedPreventionPostoperative Wound Infection1
3CompletedPreventionSurgical Site Infections1
3CompletedPreventionWound Infections1
3CompletedTreatmentAcute Otitis Externa1
3CompletedTreatmentAdenoviral Conjunctivitis / Conjunctivitis, Bacterial1
3CompletedTreatmentConjunctivitis, Viral1
3RecruitingTreatmentAbdominal Surgeries / Surgical Site Infections1
3RecruitingTreatmentMalignant Pleural Effusions1
3TerminatedPreventionVentilator-associated Bacterial Pneumonia1
3TerminatedTreatmentAdenoviral Conjunctivitis1
3TerminatedTreatmentFungal Keratitis1
3TerminatedTreatmentLeukemia Acute Myeloid Leukemia (AML) / Leukemias / Myeloid Leukemias1
3TerminatedTreatmentRecurrences / Varicosities of the great saphenous vein / Wound Infections1
3Unknown StatusPreventionEye Infections1
4Active Not RecruitingPreventionArrhythmia / Heart Failure1
4Active Not RecruitingPreventionSurgical Site Infections1
4CompletedOtherStrabismus1
4CompletedOtherSurgical Preparation of the Vagina1
4CompletedPreventionBacteraemia Post Debridement1
4CompletedPreventionBacteremia1
4CompletedPreventionHand Hygiene1
4CompletedPreventionOral Health1
4CompletedPreventionPostpartum Endometritis1
4CompletedPreventionSkin Health1
4CompletedPreventionSurgical Site Infections1
4CompletedTreatmentAmputation Wound / Wound Infections1
4CompletedTreatmentBacterial Infections1
4CompletedTreatmentConjunctivitis, Viral1
4CompletedTreatmentSkin Diseases, Infectious / Soft Tissues Infections1
4Enrolling by InvitationTreatmentFractures, Open / Open Appendicular Fracture / Surgical Site Infections / Unplanned Fracture-Related Reoperation1
4Enrolling by InvitationTreatmentGranuloma / Tracheostomy care1
4Not Yet RecruitingPreventionSurgical Site Infections1
4RecruitingOtherVaginal Surgeries1
4RecruitingPreventionCardiac Surgery in Adult Patient1
4RecruitingPreventionHospitalization / Infection NOS1
4RecruitingPreventionInfection; Cesarean Section1
4RecruitingPreventionNeoplasms, Breast / Wound Infections1
4TerminatedNot AvailableSurgical Site Infections1
4TerminatedPreventionArthroplasty, Knee Replacement / Knee Replacement Surgery1
4TerminatedPreventionCatheter Bacteraemia / Catheter Related Infections / Catheter; Infection (Indwelling Catheter) / Urinary Tract Infection1
4Unknown StatusPreventionBacteriuria / Hospital Acquired Infections / Urinary Tract Infection1
4Unknown StatusPreventionInfection NOS / Misadventure During Aspirating Needle Biopsy / Prostatic Diseases1
4WithdrawnTreatmentMalignant Pleural Effusions / Pleural Effusion Due to Congestive Heart Failure / Pleural Effusion in Conditions Classified Elsewhere / Pleural Effusions / Pleural Effusions, Chronic / Pleurodesis1
Not AvailableActive Not RecruitingScreeningMRSA/ MSSA Colonization of the Nares1
Not AvailableCompletedPreventionBacteremia1
Not AvailableCompletedPreventionColonization / Line Insertion Site1
Not AvailableCompletedPreventionInfective Complications Post-transrectal Prostate Biopsy1
Not AvailableCompletedPreventionSurgical Site Infections1
Not AvailableCompletedPreventionSuture Strabismus Surgery1
Not AvailableCompletedTreatmentCataracts1
Not AvailableCompletedTreatmentContraception1
Not AvailableCompletedTreatmentSurgical Site Infections1
Not AvailableNot Yet RecruitingPreventionWound Infections1
Not AvailableNot Yet RecruitingTreatmentOsteoarthritis (OA)1
Not AvailableRecruitingPreventionMotility Disorders / Staphylococcus Aureus1
Not AvailableRecruitingPreventionNeoplasms, Esophageal1
Not AvailableRecruitingPreventionSurgical Site Infections1
Not AvailableRecruitingTreatmentAdenoviral Conjunctivitis / Conjunctivitis1
Not AvailableRecruitingTreatmentPeriodontitis, Adult1
Not AvailableTerminatedNot AvailableBacterial blepharitis1
Not AvailableUnknown StatusDiagnosticDiabetic Macular Edema (DME) / Retinopathy, Diabetic1
Not AvailableUnknown StatusPreventionCentral Line-associated Bloodstream Infection (CLABSI) / Line Insertion Site1
Not AvailableUnknown StatusTreatmentHidradenitis Suppurativa (HS)1
Not AvailableUnknown StatusTreatmentSkin Burns1
Not AvailableUnknown StatusTreatmentWound site1
Not AvailableWithdrawnPreventionInfection NOS1
Not AvailableWithdrawnPreventionSurgical Site Infections1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
SolutionTopical5 mg/1mL
KitOphthalmic
StickTopical
SolutionTopical7.5 mg/100mL
SolutionTopical
SwabTopical0.1 mg/1mL
SolutionTopical
DoucheVaginal10 g/100g
OintmentTopical10 mg/1g
LiquidTopical10 1/100g
SolutionTopical8.1 g/100g
EmulsionTopical75 mg/1mL
Kit; liquidIntravenous
LiquidIntravenous
SolutionTopical50 mg/1mL
KitVaginal0.3 g/100mL
SolutionOphthalmic5 mg/1mL
SprayTopical.05 mL/1mL
SprayTopical.5 mg/1mL
AerosolTopical
CreamTopical0.05 mg/1mL
ShampooTopical
DressingTopical
SwabTopical.01 mL/1
DoucheVaginal
GelVaginal
SuppositoryVaginal
LiquidSubcutaneous
Liquid; ointmentIntravenous; Topical
Kit; liquid; ointmentInfiltration; Parenteral; Subcutaneous; Topical
PatchTopical100 mg/1
SwabTopical
GelTopical9.7 g/1mL
SolutionTopical9.5 g/1mL
SolutionTopical7.86 g/1mL
KitInfiltration; Subcutaneous
KitTopical
SwabTopical10 g/100g
SwabTopical7.5 g/100g
GelTopical1.20 mL/100mL
LiquidTopical10 mg/1mL
LiquidTopical100 mg/7.5mL
SpongeTopical
SolutionTopical75 mg/1mL
KitEpidural; Infiltration
Kit; ointment; solutionInfiltration; Intravenous; Topical
SolutionTopical10 mg/1mL
LiquidTopical100 mg/1mL
LiquidTopical7.5 mg/100mL
SolutionTopical0.01 g/1mL
SolutionTopical1 g/100mL
SwabTopical0.2 g/1
PatchTopical10 g/100g
KitIntra-amniotic
KitTopical
KitOral
SolutionTopical7500 mg/100mL
SolutionVaginal10 g/100mL
SuppositoryVaginal200 mg/1
Liquid; ointmentEpidural; Topical
SoapTopical3.9 g/100g
LiquidTopical
LiquidTopical10 g/100g
GelTopical10 g/100g
SpongeTopical2 g/20g
KitRespiratory (inhalation)
SolutionTopical1.18 g/118mL
SolutionTopical0.75 g/100g
SolutionTopical1 g/100g
LiquidTopical
LiquidTopical1 g/100mL
OintmentTopical100 mg/1g
LiquidTopical1 mg/10mL
ClothTopical100 mg/1mL
SolutionTopical0.1 g/1
SolutionTopical0.10 g/1
OintmentTopical10 g/100g
PatchTopical100 mg/1g
GelTopical10 mg/1mL
SpongeTopical10 mg/1mL
SpongeTopical5 mg/1mL
SolutionTopical.25 mL/5mL
KitEpidural; Intracaudal; Perineural
KitIntra-articular; Intramuscular
Liquid; ointmentSubcutaneous; Topical
IrrigantTopical10 mg/1mL
Kit; ointment; solutionInfiltration; Subcutaneous; Topical
LiquidEpidural; Intravenous
KitInfiltration; Intramuscular
SolutionTopical10 mL/100mL
SolutionTopical7.5 mg/1mL
SwabTopical10 mg/1mL
OintmentTopical1 g/10g
SolutionTopical.10 mg/1mL
SolutionTopical0.10 mg/1mL
SwabTopical1 mL/10mL
SwabTopical10 mL/100mL
SwabTopical100 mg/1mL
SpongeTopical0.1 mg/1mL
SpongeTopical7.5 mg/1mL
GelTopical0.10 g/1mL
OintmentTopical.10 g/1g
SolutionTopical.10 g/1mL
SolutionEpidural; Percutaneous; Topical.10 g/1
SwabTopical10 mg/100mL
ClothTopical10 g/1mL
SwabTopical0.75 mg/1mL
SwabTopical7.5 mg/1mL
SolutionTopical10.34 mg/1mL
SpongeTopical100 mg/1mL
SpongeTopical50 mg/1mL
SpongeTopical90 mg/1mL
Aerosol, sprayTopical0.1 g/1g
OintmentTopical1 g/100g
SolutionTopical9.8 g/100g
SwabPercutaneous0.1 mL/1
SwabTopical0.05 g/1
SolutionTopical0.75 mg/1mL
GelTopical10 mg/1g
SwabTopical9.43 g/100g
SolutionTopical0.1 g/1mL
SwabTopical1 mL/100mL
SwabTopical10 mg/1g
SwabPercutaneous10 mL/1
SwabPercutaneous10 mg/1
SwabTopical0.1 mg/1
SwabTopical0.1 mL/1mL
SwabTopical0.10 g/1
SwabTopical100 mg/1
ClothTopical10 mg/1mL
SwabTopical100 mg/1g
SolutionEpidural; Percutaneous; Topical.10 mg/1mL
SolutionEpidural; Percutaneous; Topical0.10 mg/1mL
SpongeTopical100 mg/1g
SwabTopical0.07 g/1
SpongeTopical75 mg/1g
SwabTopical75 mg/1g
SolutionTopical.075 mg/1mL
SolutionPercutaneous0.01 mg/1g
SolutionTopical1 mg/100mL
SolutionTopical1.1 mg/100mL
SolutionTopical100 mg/1mL
GelTopical
SolutionTopical10 g/100g
SolutionTopical7.5 g/100g
ClothTopical10 mg/1
LiquidVaginal
LiquidTopical10 %
OintmentTopical
EmulsionTopical7.5 mg/1mL
SwabTopical.10 g/1g
StickTopical10 mg/1mL
SolutionTopical0.006 g/0.6mL
SolutionTopical0.1 g/100mL
SolutionTopical0.75 g/100mL
SolutionTopical8 mL/100mL
SolutionTopical7.5 mg/1
SwabTopical0.9 g/100mL
SwabTopical0.9 mg/100mL
SwabTopical1 g/100mL
DoucheVaginal0.30 mL/100mL
KitVaginal.3 g/100mL
LiquidTopical5 mg/1mL
SolutionTopical9 mg/1mL
SolutionTopical15 mg/1mL
SolutionTopical0.75 mg/100mL
SolutionTopical0.15 g/100mL
SolutionTopical0.9 g/100mL
LiquidTopical8.64 g/100mL
KitBuccal
KitInfiltration; Topical
LiquidInfiltration; Subcutaneous; Topical
LiquidParenteral; Topical
KitTopical10 mg/1mL
DoucheVaginal4 g/133mL
LiquidTopical10.5 g/100mL
SwabTopical10 mg/1
SwabTopical10 mg/100mg
SolutionEpidural; Percutaneous; Topical.075 L/1L
SolutionEpidural; Percutaneous; Topical.075 mL/1mL
SolutionTopical.075 mL/1mL
SolutionTopical.10 L/1L
Prices
Not Available
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US7066916No2006-06-272024-02-17Us
US7595021No2009-09-292023-05-12Us
US7717889No2010-05-182025-02-27Us
US7935093No2011-05-032027-10-02Us
US7427574No2008-09-232026-04-25Us
Additional Data Available
  • Filed On
    Filed On

    The date on which a patent was filed with the relevant government.

    Learn more

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on September 14, 2010 10:21 / Updated on November 16, 2019 10:41