Showing BioInteractions for DB08881 (Vemurafenib)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Vemurafenib is a Serine/threonine-protein kinase B-raf inhibitor
1Serine/threonine-protein kinase B-raf inhibitorsDabrafenib, Regorafenib, Sorafenib
Interacting GroupInteracting Drugs
Vemurafenib is a Cytochrome P450 1A2 inhibitor
1Cytochrome P450 1A2 substratesAcenocoumarol, Acetaminophen, Albendazole, Almotriptan, Alosetron, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Anagrelide, Antipyrine, Apixaban, Aprepitant, Asenapine, Axitinib, Azelastine, Bendamustine, Benzyl alcohol, Betaxolol, Bortezomib, Bromazepam, Bupivacaine, Bupropion, Caffeine, Carbamazepine, Carmustine, Carvedilol, Chlorpromazine, Chlorzoxazone, Cilostazol, Cinacalcet, Cinnarizine, Cisapride, Clenbuterol, Clevidipine, Clomipramine, Clonidine, Clopidogrel, Clozapine, Conjugated estrogens, Cyclobenzaprine, Dacarbazine, Dapagliflozin, Dasatinib, Daunorubicin, Desipramine, Deutetrabenazine, Dexfenfluramine, Diazepam, Diclofenac, Dinoprostone, Diphenhydramine, Domperidone, Doxepin, Duloxetine, Eltrombopag, Enasidenib, Ergotamine, Erlotinib, Estradiol, Estrone, Estrone sulfate, Ethanol, Etoposide, Etoricoxib, Flunarizine, Flunitrazepam, Fluorouracil, Fluoxetine, Flutamide, Fluvoxamine, Frovatriptan, Genistein, Grepafloxacin, Guanabenz, Haloperidol, Hesperetin, Hexobarbital, Icotinib, Iloperidone, Imatinib, Imipramine, Imiquimod, Ixazomib, Leflunomide, Levobupivacaine, Lidocaine, Lomefloxacin, Lorcaserin, Lumiracoxib, Malathion, Maprotiline, Melatonin, Menadione, Mephenytoin, Methadone, Methoxyflurane, Mexiletine, Mianserin, Mirtazapine, Nabumetone, Naproxen, Nicotine, Nifedipine, Nitric Oxide, Nortriptyline, Olanzapine, Omeprazole, Ondansetron, Oxaliplatin, Oxtriphylline, Palonosetron, Pantoprazole, Pazopanib, Pentamidine, Pentoxifylline, Perphenazine, Phenacetin, Pimozide, Pipotiazine, Pomalidomide, Praziquantel, Primaquine, Progesterone, Proguanil, Promazine, Propafenone, Propofol, Propranolol, Pyrazinamide, Quinine, Ramelteon, Ranitidine, Rasagiline, Resveratrol, Rifabutin, Riluzole, Ritonavir, Rizatriptan, Rofecoxib, Ropinirole, Ropivacaine, Rotigotine, Rucaparib, Selegiline, Sertraline, Stiripentol, Tacrine, Tamoxifen, Telithromycin, Temafloxacin, Terbinafine, Thalidomide, Theobromine, Theophylline, Thiabendazole, Thioridazine, Thiothixene, Tizanidine, Toremifene, Triamterene, Trifluoperazine, Ulipristal, Vadimezan, Verapamil, Voxilaprevir, Warfarin, Zileuton, Ziprasidone, Zolmitriptan, Zolpidem
2Cytochrome P450 1A2 inhibitorsAbiraterone, Aciclovir, Agomelatine, Albendazole, Alitretinoin, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Anastrozole, Apomorphine, Atazanavir, Atropine, Azithromycin, Bortezomib, Bromocriptine, Buprenorphine, Caffeine, Carbamazepine, Carbimazole, Cimetidine, Ciprofloxacin, Citalopram, Clarithromycin, Clobetasol propionate, Clomifene, Clotrimazole, Clozapine, Conjugated estrogens, Crisaborole, Delavirdine, Desloratadine, Dexfenfluramine, Dexmedetomidine, Diacerein, Diazepam, Diclofenac, Disulfiram, Dopamine, Dosulepin, Edetic Acid, Efavirenz, Eltrombopag, Enasidenib, Enoxacin, Entacapone, Epinephrine, Erythromycin, Estradiol, Etoricoxib, Fluconazole, Fluoxetine, Fluphenazine, Flutamide, Fluvastatin, Fluvoxamine, Gemfibrozil, Glecaprevir, Glycerol Phenylbutyrate, Imipramine, Interferon Alfa-2b, Recombinant, Interferon gamma-1b, Irbesartan, Isoniazid, Ketoconazole, Levofloxacin, Lidocaine, Lobeglitazone, Lomefloxacin, Lopinavir, Losartan, Manidipine, Meclizine, Melatonin, Mestranol, Methimazole, Methotrimeprazine, Methoxsalen, Mexiletine, Mibefradil, Miconazole, Midostaurin, Mifepristone, Mirtazapine, Moclobemide, Modafinil, Nefazodone, Nelfinavir, Nevirapine, Niclosamide, Nifedipine, Nilvadipine, Nisoldipine, Nitroprusside, Norepinephrine, Norfloxacin, Obeticholic acid, Ofloxacin, Olanzapine, Omeprazole, Ondansetron, Orphenadrine, Oxymetholone, Paroxetine, Pefloxacin, Peginterferon alfa-2a, Peginterferon alfa-2b, Pentoxifylline, Perphenazine, Phentermine, Phenylbutyric acid, Phenylpropanolamine, Pibrentasvir, Primaquine, Propafenone, Propofol, Propranolol, Quinidine, Quinine, Ranitidine, Resveratrol, Rhein, Rofecoxib, Ropinirole, Rosiglitazone, Rotigotine, Roxithromycin, Selegiline, Sertraline, Simeprevir, Sorafenib, Sulconazole, Sulindac, Synthetic Conjugated Estrogens, A, Tegaserod, Temafloxacin, Tenofovir disoproxil, Theophylline, Thiabendazole, Thioridazine, Ticlopidine, Tioconazole, Tocainide, Topiroxostat, Tranylcypromine, Triamterene, Valaciclovir, Valproic Acid, Verapamil, Zafirlukast, Zileuton, Zucapsaicin
3Cytochrome P450 1A2 inducersAlbendazole, Aminoglutethimide, Armodafinil, Belinostat, beta-Naphthoflavone, Capsaicin, Carbamazepine, Danthron, Griseofulvin, Insulin Aspart, Insulin Beef, Insulin Detemir, Insulin Glargine, Insulin Glulisine, Insulin Human, Insulin Lispro, Insulin Pork, Lansoprazole, Menadione, Midostaurin, Modafinil, Nafcillin, Nicotine, Omeprazole, Osimertinib, Pantoprazole, Phenobarbital, Phenylephrine, Primaquine, Primidone, Quinine, Rabeprazole, Resveratrol, Rifampicin, Rilpivirine, Ritonavir, Secobarbital, Streptozocin
Interacting GroupInteracting Drugs
Vemurafenib is a Cytochrome P450 2D6 inhibitor
1Cytochrome P450 2D6 substrates4-Methoxyamphetamine, Acetaminophen, Acetylcholine, Ajmaline, Almotriptan, Alogliptin, Alprenolol, Aminophenazone, Amiodarone, Amitriptyline, Amoxapine, Amphetamine, Amprenavir, Amsacrine, Antipyrine, Aprindine, Arformoterol, Aripiprazole, Artemether, Astemizole, Atomoxetine, Azelastine, Benzatropine, Benzyl alcohol, Bepridil, Betaxolol, Bisoprolol, Bortezomib, Brexpiprazole, Brompheniramine, Bufuralol, Bupivacaine, Buprenorphine, Bupropion, Buspirone, Caffeine, Captopril, Cariprazine, Carteolol, Carvedilol, Cephalexin, Cevimeline, Chlordiazepoxide, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cilostazol, Cinnarizine, Citalopram, Clevidipine, Clomipramine, Clonidine, Clozapine, Codeine, Cyclobenzaprine, Cyclophosphamide, Dapagliflozin, Darifenacin, Dasabuvir, Debrisoquin, Delavirdine, Desipramine, Deutetrabenazine, Dexchlorpheniramine maleate, Dexfenfluramine, Dexmethylphenidate, Dextroamphetamine, Dextromethorphan, Dihydrocodeine, Diltiazem, Diphenhydramine, Dolasetron, Domperidone, Donepezil, Dopamine, Doxazosin, Doxepin, Doxorubicin, Dronedarone, Duloxetine, Eletriptan, Eliglustat, Enasidenib, Encainide, Enclomiphene, Epinastine, Erlotinib, Escitalopram, Esmirtazapine, Ethylmorphine, Etoricoxib, Fesoterodine, Fingolimod, Flecainide, Flunarizine, Fluoxetine, Fluphenazine, Fluvastatin, Fluvoxamine, Formoterol, Galantamine, Gefitinib, Granisetron, Halofantrine, Haloperidol, Halothane, Hydrocodone, Hydromorphone, Ibrutinib, Idarubicin, Iloperidone, Imatinib, Imipramine, Ipratropium bromide, Ixazomib, Labetalol, Levodopa, Levomilnacipran, Lidocaine, Lisuride, Lomustine, Loperamide, Loratadine, Lorcaserin, Maprotiline, Mephenytoin, Mequitazine, Mesoridazine, Methadone, Methamphetamine, Methotrimeprazine, Methoxyflurane, Methylphenidate, Methyprylon, Metoclopramide, Metoprolol, Mexiletine, Mianserin, Minaprine, Mirabegron, Mirtazapine, Moclobemide, Morphine, Nateglinide, Nebivolol, Nefazodone, Netupitant, Nevirapine, Nicardipine, Nicergoline, Nicotine, Nifedipine, Nitrofural, Nortriptyline, Olanzapine, Ondansetron, Oxycodone, Oxymorphone, Palonosetron, Paroxetine, Pazopanib, Pentamidine, Perhexiline, Perospirone, Perphenazine, Pethidine, Phenacetin, Phenformin, Pindolol, Piperazine, Pipotiazine, Ponatinib, Procainamide, Prochlorperazine, Progesterone, Promethazine, Propafenone, Propofol, Propranolol, Protriptyline, Pseudoephedrine, Quetiapine, Quinine, Ranitidine, Remoxipride, Risperidone, Ritonavir, Ropivacaine, Rotigotine, Rucaparib, Rupatadine, Saquinavir, Sertindole, Sertraline, Sildenafil, Simvastatin, Sparteine, Tamoxifen, Tamsulosin, Tapentadol, Tegaserod, Terfenadine, Tesmilifene, Tetrabenazine, Theophylline, Thioridazine, Ticlopidine, Timolol, Tiotropium, Tipranavir, Tolterodine, Trabectedin, Tramadol, Trazodone, Trimipramine, Umeclidinium, Valbenazine, Venlafaxine, Vernakalant, Vilazodone, Vinblastine, Vinorelbine, Vortioxetine, Yohimbine, Zalcitabine, Zolpidem, Zuclopenthixol
2Cytochrome P450 2D6 inhibitorsAbiraterone, Acebutolol, Ajmaline, Amiodarone, Amitriptyline, Amlodipine, Amodiaquine, Amphetamine, Antipyrine, Aripiprazole, Artemether, Asenapine, Atomoxetine, Atorvastatin, Azelastine, Betaxolol, Bicalutamide, Biperiden, Bortezomib, Brompheniramine, Buprenorphine, Bupropion, Carbinoxamine, Carteolol, Celecoxib, Cerivastatin, Chloroquine, Chlorphenamine, Chlorpromazine, Cholecalciferol, Cimetidine, Cinacalcet, Cisapride, Citalopram, Clemastine, Clobazam, Clomipramine, Clotrimazole, Clozapine, Cobicistat, Cocaine, Codeine, Cyclosporine, Cyproterone acetate, Darifenacin, Delavirdine, Deramciclane, Desipramine, Desloratadine, Dexfenfluramine, Dexmedetomidine, Dexmethylphenidate, Dextroamphetamine, Dextromethorphan, Dextropropoxyphene, Diacerein, Diltiazem, Dimethyl sulfoxide, Diphenhydramine, Disulfiram, Dolasetron, Dosulepin, Doxepin, Doxorubicin, Dronedarone, Duloxetine, Efavirenz, Eliglustat, Enasidenib, Entacapone, Enzalutamide, Epinastine, Escitalopram, Etoricoxib, Felodipine, Fenfluramine, Fexofenadine, Flecainide, Fluoxetine, Fluphenazine, Fluvastatin, Fluvoxamine, Gefitinib, Glycerol Phenylbutyrate, Granisetron, Halofantrine, Haloperidol, Histamine, Hydroxychloroquine, Hydroxyurea, Hydroxyzine, Idarubicin, Imatinib, Imipramine, Indinavir, Irbesartan, Isoniazid, Itraconazole, Ketoconazole, Labetalol, Lansoprazole, Lercanidipine, Levosalbutamol, Lidocaine, Lomustine, Lopinavir, Loratadine, Lorcaserin, Lovastatin, Lumefantrine, Manidipine, Mefloquine, Mepyramine, Methadone, Methamphetamine, Methazolamide, Methimazole, Methotrimeprazine, Methoxsalen, Methylnaltrexone, Methylphenidate, Metoclopramide, Metoprolol, Mianserin, Mibefradil, Miconazole, Midodrine, Midostaurin, Mifepristone, Mirabegron, Mirtazapine, Moclobemide, Naloxegol, Nefazodone, Nelfinavir, Nevirapine, Niacin, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nortriptyline, Olanzapine, Omeprazole, Ondansetron, Ospemifene, Oxamniquine, Oxprenolol, Oxybutynin, Oxymetholone, Panobinostat, Paroxetine, Pazopanib, Peginterferon alfa-2b, Pentamidine, Pergolide, Perhexiline, Perphenazine, Phentermine, Phenylbutyric acid, Pimozide, Pindolol, Pioglitazone, Pipotiazine, Pravastatin, Praziquantel, Primaquine, Proguanil, Promazine, Promethazine, Propafenone, Propofol, Propoxyphene napsylate, Propranolol, Pyrimethamine, Quetiapine, Quinidine, Quinine, Rabeprazole, Ranitidine, Ranolazine, Reboxetine, Rhein, Risperidone, Ritonavir, Rivastigmine, Rolapitant, Ropinirole, Rosiglitazone, Rotigotine, Rutin, Saquinavir, Selegiline, Sertraline, Sildenafil, Simvastatin, Sorafenib, Sparteine, Stiripentol, Sulconazole, Sulfanilamide, Sulfaphenazole, Tamoxifen, Tapentadol, Tegaserod, Telithromycin, Temsirolimus, Terbinafine, Terfenadine, Thioridazine, Thiothixene, Ticagrelor, Ticlopidine, Timolol, Tioconazole, Tipranavir, Tramadol, Tranylcypromine, Tripelennamine, Triprolidine, Trospium, Venlafaxine, Verapamil, Vernakalant, Vilazodone, Vinblastine, Vinorelbine, Yohimbine, Zafirlukast, Ziprasidone, Zucapsaicin
3Cytochrome P450 2D6 inducersAripiprazole, Dexamethasone, Glutethimide, Granisetron, Haloperidol, Loratadine, Mirtazapine, Moclobemide, Pindolol, Reboxetine, Rifapentine
Interacting GroupInteracting Drugs
Vemurafenib is a Cytochrome P450 3A4 substrate
1Cytochrome P450 3A4 substratesAbemaciclib, Abiraterone, Acenocoumarol, Acetaminophen, Adinazolam, Albendazole, Alclometasone, Alfentanil, Alfuzosin, Aliskiren, Allylestrenol, Almotriptan, Alogliptin, Alosetron, Alprazolam, Ambrisentan, Ambroxol, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Amprenavir, Antipyrine, Apixaban, Apremilast, Aprepitant, Argatroban, Aripiprazole, Artemether, Asenapine, Astemizole, Atazanavir, Atorvastatin, Avanafil, Axitinib, Azelastine, Azithromycin, Banoxantrone, Bedaquiline, Benzphetamine, Benzyl alcohol, Bexarotene, Bezafibrate, Bicalutamide, Bisoprolol, Boceprevir, Bortezomib, Bosentan, Bosutinib, Brentuximab vedotin, Brexpiprazole, Brinzolamide, Brivaracetam, Bromazepam, Bromocriptine, Brompheniramine, Budesonide, Bupivacaine, Buprenorphine, Bupropion, Buspirone, Busulfan, Cabazitaxel, Cabergoline, Cabozantinib, Caffeine, Calcitriol, Canagliflozin, Carbamazepine, Carbinoxamine, Cariprazine, Carvedilol, Celecoxib, Celiprolol, Cephalexin, Cerivastatin, Cevimeline, Chenodeoxycholic acid, Chlordiazepoxide, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cholecalciferol, Ciclesonide, Cilostazol, Cinacalcet, Cisapride, Citalopram, Clarithromycin, Clindamycin, Clobazam, Clofazimine, Clofibrate, clomethiazole, Clomipramine, Clonazepam, Clonidine, Clopidogrel, Clorazepate, Clotiazepam, Clozapine, Cocaine, Codeine, Colchicine, Conivaptan, Conjugated estrogens, Copanlisib, Cortisone acetate, Crizotinib, Cyclobenzaprine, Cyclophosphamide, Cyclosporine, Cytarabine, Dabrafenib, Daclatasvir, Dantrolene, Dapagliflozin, Dapsone, Darifenacin, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Deflazacort, Delavirdine, Desvenlafaxine, Deutetrabenazine, Dexamethasone, Dexchlorpheniramine maleate, Dexlansoprazole, Dextromethorphan, Dextropropoxyphene, Diazepam, Diclofenac, Dienogest, Digitoxin, Digoxin, Dihydrocodeine, Dihydroergotamine, Diltiazem, Disopyramide, Disulfiram, Docetaxel, Dofetilide, Dolasetron, Domperidone, Donepezil, Dorzolamide, Doxepin, Doxorubicin, Dronabinol, Dronedarone, Dutasteride, Efavirenz, Elbasvir, Eletriptan, Eliglustat, Elvitegravir, Enalapril, Enasidenib, Enzalutamide, Epinastine, Eplerenone, Ergocalciferol, Ergoloid mesylate, Ergonovine, Ergotamine, Erlotinib, Erythromycin, Escitalopram, Esomeprazole, Estazolam, Estradiol, Estramustine, Estrogens, esterified, Estrone, Estrone sulfate, Eszopiclone, Ethanol, Ethinyl Estradiol, Ethosuximide, Ethylmorphine, Etizolam, Etonogestrel, Etoposide, Etoricoxib, Etravirine, Everolimus, Exemestane, Famciclovir, Felbamate, Felodipine, Fenofibrate, Fentanyl, Fesoterodine, Finasteride, Fingolimod, Flibanserin, Flunisolide, Flunitrazepam, Fluorometholone, Fluoxetine, Flurazepam, Flutamide, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fosamprenavir, Fulvestrant, Galantamine, Gefitinib, Gemfibrozil, Glipizide, Glyburide, Granisetron, Grazoprevir, Grepafloxacin, Guanfacine, Halofantrine, Haloperidol, Halothane, Hexobarbital, Histamine, Hydrocodone, Hydrocortisone, Hydromorphone, Hydroxyprogesterone caproate, Ibrutinib, Icotinib, Ifosfamide, Iloperidone, Imatinib, Imidafenacin, Imipramine, Imiquimod, Indacaterol, Indapamide, Indinavir, Ipratropium bromide, Irinotecan, Isavuconazonium, Isosorbide Dinitrate, Isosorbide Mononitrate, Isradipine, Itraconazole, Ivabradine, Ivacaftor, Ivermectin, Ixabepilone, Ixazomib, Ketamine, Ketazolam, Ketobemidone, Ketoconazole, Lansoprazole, Lapatinib, Laquinimod, Lenvatinib, Lercanidipine, Letrozole, Levobupivacaine, Levocetirizine, Levomethadyl Acetate, Levomilnacipran, Levonorgestrel, Levothyroxine, Lidocaine, Lisuride, Lomitapide, Loperamide, Lopinavir, Loratadine, Lorcaserin, Losartan, Lovastatin, Lumefantrine, Lurasidone, Macitentan, Maraviroc, Mebendazole, Medroxyprogesterone acetate, Mefloquine, Meloxicam, Methadone, Methaqualone, Methoxsalen, Methoxyflurane, Methylprednisolone, Methyltestosterone, Metronidazole, Mexiletine, Mianserin, Mibefradil, Miconazole, Midazolam, Midostaurin, Mifepristone, Mirabegron, Mirtazapine, Modafinil, Montelukast, Morphine, Mycophenolate mofetil, Naloxegol, Naloxone, Nateglinide, Nefazodone, Nelfinavir, Neratinib, Nevirapine, Nicardipine, Nicotine, Nifedipine, Nilotinib, Nilvadipine, Nimodipine, Nisoldipine, Nitrazepam, Nitrendipine, Norethisterone, Norgestrel, Nortriptyline, Odanacatib, Olaparib, Olopatadine, Omeprazole, Ondansetron, Orphenadrine, Ospemifene, Oxazepam, Oxybutynin, Oxycodone, Oxymorphone, Paclitaxel, Palbociclib, Palonosetron, Panobinostat, Pantoprazole, Paramethadione, Paramethasone, Parecoxib, Paricalcitol, Paritaprevir, Pazopanib, Pentamidine, Perampanel, Pergolide, Perhexiline, Permethrin, Perospirone, Perphenazine, Pethidine, Phenacetin, Phenoxybenzamine, Phenprocoumon, Phenytoin, Pilocarpine, Pimecrolimus, Pimozide, Pioglitazone, Pipotiazine, Podofilox, Pomalidomide, Ponatinib, Posaconazole, Prasterone, Prasugrel, Pravastatin, Prazepam, Praziquantel, Prednisolone, Prednisone, Primaquine, Prochlorperazine, Progesterone, Proguanil, Promazine, Propafenone, Propofol, Propoxyphene napsylate, Propranolol, Pyrazinamide, Quazepam, Quetiapine, Quinacrine, Quinidine, Quinine, Rabeprazole, Raloxifene, Ramelteon, Ranolazine, Reboxetine, Regorafenib, Repaglinide, Retapamulin, Rifabutin, Rifampicin, Rilpivirine, Rimonabant, Riociguat, Risperidone, Ritonavir, Rivaroxaban, Rofecoxib, Rolapitant, Romidepsin, Ropinirole, Ropivacaine, Rosuvastatin, Rotigotine, Roxithromycin, Rucaparib, Rupatadine, Ruxolitinib, Safinamide, Salmeterol, Saquinavir, Saxagliptin, Selegiline, Selexipag, Seratrodast, Sertindole, Sertraline, Sevoflurane, Sibutramine, Sildenafil, Silodosin, Simvastatin, Sirolimus, Sitagliptin, Solifenacin, Sonidegib, Sorafenib, Spiramycin, Sufentanil, Sulfadiazine, Sulfamethoxazole, Sulfinpyrazone, Sunitinib, Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B, Tacrolimus, Tadalafil, Tamoxifen, Tamsulosin, Tasosartan, Telaprevir, Telithromycin, Temazepam, Temsirolimus, Teniposide, Terbinafine, Terfenadine, Tesmilifene, Testosterone, Tetracycline, Theophylline, Thiotepa, Tiagabine, Ticagrelor, Ticlopidine, Tinidazole, Tiotropium, Tipranavir, Tofacitinib, Tolterodine, Tolvaptan, Toremifene, Trabectedin, Tramadol, Trastuzumab emtansine, Trazodone, Tretinoin, Triamcinolone, Triazolam, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Troleandomycin, Udenafil, Ulipristal, Valbenazine, Valdecoxib, Vandetanib, Vanoxerine, Vardenafil, Velpatasvir, Venetoclax, Venlafaxine, Verapamil, Vilanterol, Vilazodone, Vinblastine, Vincristine, Vindesine, Vinorelbine, Vismodegib, Voriconazole, Vortioxetine, Voxilaprevir, Warfarin, Yohimbine, Zafirlukast, Zalcitabine, Zaleplon, Zidovudine, Zileuton, Ziprasidone, Zolpidem, Zomepirac, Zonisamide, Zopiclone
2Cytochrome P450 3A4 inhibitorsAcetaminophen, Acetazolamide, Aldesleukin, Alprazolam, Ambroxol, Amiodarone, Amlodipine, Amprenavir, Anastrozole, Antipyrine, Aprepitant, Arsenic trioxide, Astemizole, Atazanavir, Atomoxetine, Atorvastatin, Azelastine, Azithromycin, Betamethasone, Bicalutamide, Bifonazole, Boceprevir, Bortezomib, Brentuximab vedotin, Bromocriptine, Buprenorphine, Cabergoline, Caffeine, Capsaicin, Caspofungin, Ceritinib, Cerivastatin, Chloramphenicol, Chlorzoxazone, Cilostazol, Cimetidine, Ciprofloxacin, Cisapride, Clarithromycin, Clemastine, Clindamycin, Clofazimine, Clomifene, Clotiazepam, Clotrimazole, Clozapine, Cobicistat, Cocaine, Colchicine, Conivaptan, Cortisone acetate, Crizotinib, Cyclophosphamide, Cyclosporine, Dalfopristin, Danazol, Darunavir, Dasatinib, Daunorubicin, Delavirdine, Desipramine, Dexamethasone, Dextropropoxyphene, Diazepam, Diethylstilbestrol, Dihydroergotamine, Diltiazem, Dimethyl sulfoxide, Docetaxel, Doxorubicin, Doxycycline, Dronedarone, Econazole, Efavirenz, Elbasvir, Enasidenib, Epinephrine, Ergoloid mesylate, Ergonovine, Ergotamine, Erythromycin, Ethanol, Etoposide, Etoricoxib, Ezetimibe, Felodipine, Fentanyl, Fluconazole, Fluoxetine, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Gemfibrozil, Glyburide, Glycerol Phenylbutyrate, Haloperidol, Histamine, Hydralazine, Hydrocortisone, Idelalisib, Ifosfamide, Iloperidone, Imatinib, Indinavir, Irbesartan, Irinotecan, Isavuconazonium, Isoniazid, Isradipine, Itraconazole, Ivacaftor, Josamycin, Ketazolam, Ketoconazole, Lansoprazole, Lapatinib, Lercanidipine, Levofloxacin, Levosalbutamol, Lidocaine, Linagliptin, Lomitapide, Lomustine, Lopinavir, Loratadine, Losartan, Lovastatin, Luliconazole, Lurasidone, Manidipine, Mefloquine, Mequitazine, Methadone, Methazolamide, Methimazole, Methylergometrine, Methylprednisolone, Metronidazole, Metyrapone, Mibefradil, Miconazole, Midazolam, Mifepristone, Mirtazapine, Mitoxantrone, Modafinil, Nefazodone, Nelfinavir, Netupitant, Nevirapine, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nilvadipine, Nisoldipine, Nitrendipine, Nitric Oxide, Norfloxacin, Olanzapine, Olaparib, Omeprazole, Oxybutynin, Oxymetholone, Paclitaxel, Palbociclib, Paramethasone, Pazopanib, Pergolide, Phenelzine, Pilocarpine, Pimozide, Posaconazole, Pravastatin, Prednisolone, Prednisone, Primaquine, Progesterone, Propofol, Quinidine, Quinine, Quinupristin, Rabeprazole, Raloxifene, Ranitidine, Ranolazine, Regorafenib, Repaglinide, Resveratrol, Rilpivirine, Risperidone, Ritonavir, Rivastigmine, Rolitetracycline, Rosuvastatin, Roxithromycin, Rutin, Salbutamol, Saquinavir, Sarilumab, Sertraline, Sildenafil, Simeprevir, Simvastatin, Sirolimus, Sitaxentan, Sorafenib, Stiripentol, Sulfamethoxazole, Sulfanilamide, Sulfinpyrazone, Sulfisoxazole, Tacrolimus, Tadalafil, Tamoxifen, Telaprevir, Telithromycin, Temsirolimus, Teniposide, Terfenadine, Tesmilifene, Testosterone, Tetracycline, Thiopental, Ticagrelor, Ticlopidine, Tioconazole, Tipranavir, Tofisopam, Topiroxostat, Topotecan, Tramadol, Tranylcypromine, Troglitazone, Troleandomycin, Valproic Acid, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinorelbine, Voriconazole, Zafirlukast, Ziprasidone, Zucapsaicin
3Cytochrome P450 3A4 inducersAcetaminophen, Alclometasone, Alimemazine, Aminoglutethimide, Armodafinil, Artemether, Atorvastatin, Azatadine, Bexarotene, Bosentan, Calcitriol, Carbamazepine, Cefradine, Cerivastatin, Chlorphenesin, Clarithromycin, Clevidipine, Clobazam, Clofibrate, Clotrimazole, Clozapine, Colchicine, Cyclophosphamide, Dabrafenib, Deferasirox, Delafloxacin, Desvenlafaxine, Dexamethasone, Dicloxacillin, Drospirenone, Efavirenz, Eletriptan, Enasidenib, Enzalutamide, Eslicarbazepine acetate, Estradiol, Ethanol, Etoposide, Etravirine, Exemestane, Felbamate, Flucloxacillin, Fluorometholone, Fluvastatin, Fosaprepitant, Fosphenytoin, Gemfibrozil, Griseofulvin, Guanethidine, Hydrocortamate, Hydrocortisone, Idelalisib, Ifosfamide, Isavuconazonium, Lansoprazole, Lopinavir, Loratadine, Lumacaftor, Lumefantrine, Medroxyprogesterone acetate, Metamizole, Methadone, Metyrapone, Midostaurin, Mifepristone, Mitotane, Modafinil, Nafcillin, Nevirapine, Nicardipine, Nifedipine, Norgestimate, Omeprazole, Oritavancin, Orlistat, Osimertinib, Oxcarbazepine, Oxiconazole, Paclitaxel, Pantoprazole, Pegvisomant, Pentobarbital, Perampanel, Phenobarbital, Phenylbutazone, Phenytoin, Pioglitazone, Prednisone, Primidone, Probenecid, Progesterone, Pyridostigmine, Quinidine, Quinine, Rifabutin, Rifampicin, Rifapentine, Rifaximin, Rilpivirine, Ritonavir, Rofecoxib, Rufinamide, Seratrodast, Simvastatin, St. John's Wort, Sulfinpyrazone, Tamoxifen, Temozolomide, Terbinafine, Terfenadine, Tesmilifene, Testosterone, Topiramate, Topotecan, Trametinib, Troglitazone
Interacting GroupInteracting Drugs
Vemurafenib is a Cytochrome P450 3A4 inducer
1Cytochrome P450 3A4 substratesAbemaciclib, Abiraterone, Acenocoumarol, Acetaminophen, Adinazolam, Albendazole, Alclometasone, Alfentanil, Alfuzosin, Aliskiren, Allylestrenol, Almotriptan, Alogliptin, Alosetron, Alprazolam, Ambrisentan, Ambroxol, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Amprenavir, Antipyrine, Apixaban, Apremilast, Aprepitant, Argatroban, Aripiprazole, Artemether, Asenapine, Astemizole, Atazanavir, Atorvastatin, Avanafil, Axitinib, Azelastine, Azithromycin, Banoxantrone, Bedaquiline, Benzphetamine, Benzyl alcohol, Bexarotene, Bezafibrate, Bicalutamide, Bisoprolol, Boceprevir, Bortezomib, Bosentan, Bosutinib, Brentuximab vedotin, Brexpiprazole, Brinzolamide, Brivaracetam, Bromazepam, Bromocriptine, Brompheniramine, Budesonide, Bupivacaine, Buprenorphine, Bupropion, Buspirone, Busulfan, Cabazitaxel, Cabergoline, Cabozantinib, Caffeine, Calcitriol, Canagliflozin, Carbamazepine, Carbinoxamine, Cariprazine, Carvedilol, Celecoxib, Celiprolol, Cephalexin, Cerivastatin, Cevimeline, Chenodeoxycholic acid, Chlordiazepoxide, Chloroquine, Chlorphenamine, Chlorpromazine, Chlorzoxazone, Cholecalciferol, Ciclesonide, Cilostazol, Cinacalcet, Cisapride, Citalopram, Clarithromycin, Clindamycin, Clobazam, Clofazimine, Clofibrate, clomethiazole, Clomipramine, Clonazepam, Clonidine, Clopidogrel, Clorazepate, Clotiazepam, Clozapine, Cocaine, Codeine, Colchicine, Conivaptan, Conjugated estrogens, Copanlisib, Cortisone acetate, Crizotinib, Cyclobenzaprine, Cyclophosphamide, Cyclosporine, Cytarabine, Dabrafenib, Daclatasvir, Dantrolene, Dapagliflozin, Dapsone, Darifenacin, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Deflazacort, Delavirdine, Desvenlafaxine, Deutetrabenazine, Dexamethasone, Dexchlorpheniramine maleate, Dexlansoprazole, Dextromethorphan, Dextropropoxyphene, Diazepam, Diclofenac, Dienogest, Digitoxin, Digoxin, Dihydrocodeine, Dihydroergotamine, Diltiazem, Disopyramide, Disulfiram, Docetaxel, Dofetilide, Dolasetron, Domperidone, Donepezil, Dorzolamide, Doxepin, Doxorubicin, Dronabinol, Dronedarone, Dutasteride, Efavirenz, Elbasvir, Eletriptan, Eliglustat, Elvitegravir, Enalapril, Enasidenib, Enzalutamide, Epinastine, Eplerenone, Ergocalciferol, Ergoloid mesylate, Ergonovine, Ergotamine, Erlotinib, Erythromycin, Escitalopram, Esomeprazole, Estazolam, Estradiol, Estramustine, Estrogens, esterified, Estrone, Estrone sulfate, Eszopiclone, Ethanol, Ethinyl Estradiol, Ethosuximide, Ethylmorphine, Etizolam, Etonogestrel, Etoposide, Etoricoxib, Etravirine, Everolimus, Exemestane, Famciclovir, Felbamate, Felodipine, Fenofibrate, Fentanyl, Fesoterodine, Finasteride, Fingolimod, Flibanserin, Flunisolide, Flunitrazepam, Fluorometholone, Fluoxetine, Flurazepam, Flutamide, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fosamprenavir, Fulvestrant, Galantamine, Gefitinib, Gemfibrozil, Glipizide, Glyburide, Granisetron, Grazoprevir, Grepafloxacin, Guanfacine, Halofantrine, Haloperidol, Halothane, Hexobarbital, Histamine, Hydrocodone, Hydrocortisone, Hydromorphone, Hydroxyprogesterone caproate, Ibrutinib, Icotinib, Ifosfamide, Iloperidone, Imatinib, Imidafenacin, Imipramine, Imiquimod, Indacaterol, Indapamide, Indinavir, Ipratropium bromide, Irinotecan, Isavuconazonium, Isosorbide Dinitrate, Isosorbide Mononitrate, Isradipine, Itraconazole, Ivabradine, Ivacaftor, Ivermectin, Ixabepilone, Ixazomib, Ketamine, Ketazolam, Ketobemidone, Ketoconazole, Lansoprazole, Lapatinib, Laquinimod, Lenvatinib, Lercanidipine, Letrozole, Levobupivacaine, Levocetirizine, Levomethadyl Acetate, Levomilnacipran, Levonorgestrel, Levothyroxine, Lidocaine, Lisuride, Lomitapide, Loperamide, Lopinavir, Loratadine, Lorcaserin, Losartan, Lovastatin, Lumefantrine, Lurasidone, Macitentan, Maraviroc, Mebendazole, Medroxyprogesterone acetate, Mefloquine, Meloxicam, Methadone, Methaqualone, Methoxsalen, Methoxyflurane, Methylprednisolone, Methyltestosterone, Metronidazole, Mexiletine, Mianserin, Mibefradil, Miconazole, Midazolam, Midostaurin, Mifepristone, Mirabegron, Mirtazapine, Modafinil, Montelukast, Morphine, Mycophenolate mofetil, Naloxegol, Naloxone, Nateglinide, Nefazodone, Nelfinavir, Neratinib, Nevirapine, Nicardipine, Nicotine, Nifedipine, Nilotinib, Nilvadipine, Nimodipine, Nisoldipine, Nitrazepam, Nitrendipine, Norethisterone, Norgestrel, Nortriptyline, Odanacatib, Olaparib, Olopatadine, Omeprazole, Ondansetron, Orphenadrine, Ospemifene, Oxazepam, Oxybutynin, Oxycodone, Oxymorphone, Paclitaxel, Palbociclib, Palonosetron, Panobinostat, Pantoprazole, Paramethadione, Paramethasone, Parecoxib, Paricalcitol, Paritaprevir, Pazopanib, Pentamidine, Perampanel, Pergolide, Perhexiline, Permethrin, Perospirone, Perphenazine, Pethidine, Phenacetin, Phenoxybenzamine, Phenprocoumon, Phenytoin, Pilocarpine, Pimecrolimus, Pimozide, Pioglitazone, Pipotiazine, Podofilox, Pomalidomide, Ponatinib, Posaconazole, Prasterone, Prasugrel, Pravastatin, Prazepam, Praziquantel, Prednisolone, Prednisone, Primaquine, Prochlorperazine, Progesterone, Proguanil, Promazine, Propafenone, Propofol, Propoxyphene napsylate, Propranolol, Pyrazinamide, Quazepam, Quetiapine, Quinacrine, Quinidine, Quinine, Rabeprazole, Raloxifene, Ramelteon, Ranolazine, Reboxetine, Regorafenib, Repaglinide, Retapamulin, Rifabutin, Rifampicin, Rilpivirine, Rimonabant, Riociguat, Risperidone, Ritonavir, Rivaroxaban, Rofecoxib, Rolapitant, Romidepsin, Ropinirole, Ropivacaine, Rosuvastatin, Rotigotine, Roxithromycin, Rucaparib, Rupatadine, Ruxolitinib, Safinamide, Salmeterol, Saquinavir, Saxagliptin, Selegiline, Selexipag, Seratrodast, Sertindole, Sertraline, Sevoflurane, Sibutramine, Sildenafil, Silodosin, Simvastatin, Sirolimus, Sitagliptin, Solifenacin, Sonidegib, Sorafenib, Spiramycin, Sufentanil, Sulfadiazine, Sulfamethoxazole, Sulfinpyrazone, Sunitinib, Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B, Tacrolimus, Tadalafil, Tamoxifen, Tamsulosin, Tasosartan, Telaprevir, Telithromycin, Temazepam, Temsirolimus, Teniposide, Terbinafine, Terfenadine, Tesmilifene, Testosterone, Tetracycline, Theophylline, Thiotepa, Tiagabine, Ticagrelor, Ticlopidine, Tinidazole, Tiotropium, Tipranavir, Tofacitinib, Tolterodine, Tolvaptan, Toremifene, Trabectedin, Tramadol, Trastuzumab emtansine, Trazodone, Tretinoin, Triamcinolone, Triazolam, Trimethadione, Trimethoprim, Trimipramine, Troglitazone, Troleandomycin, Udenafil, Ulipristal, Valbenazine, Valdecoxib, Vandetanib, Vanoxerine, Vardenafil, Velpatasvir, Venetoclax, Venlafaxine, Verapamil, Vilanterol, Vilazodone, Vinblastine, Vincristine, Vindesine, Vinorelbine, Vismodegib, Voriconazole, Vortioxetine, Voxilaprevir, Warfarin, Yohimbine, Zafirlukast, Zalcitabine, Zaleplon, Zidovudine, Zileuton, Ziprasidone, Zolpidem, Zomepirac, Zonisamide, Zopiclone
2Cytochrome P450 3A4 inhibitorsAcetaminophen, Acetazolamide, Aldesleukin, Alprazolam, Ambroxol, Amiodarone, Amlodipine, Amprenavir, Anastrozole, Antipyrine, Aprepitant, Arsenic trioxide, Astemizole, Atazanavir, Atomoxetine, Atorvastatin, Azelastine, Azithromycin, Betamethasone, Bicalutamide, Bifonazole, Boceprevir, Bortezomib, Brentuximab vedotin, Bromocriptine, Buprenorphine, Cabergoline, Caffeine, Capsaicin, Caspofungin, Ceritinib, Cerivastatin, Chloramphenicol, Chlorzoxazone, Cilostazol, Cimetidine, Ciprofloxacin, Cisapride, Clarithromycin, Clemastine, Clindamycin, Clofazimine, Clomifene, Clotiazepam, Clotrimazole, Clozapine, Cobicistat, Cocaine, Colchicine, Conivaptan, Cortisone acetate, Crizotinib, Cyclophosphamide, Cyclosporine, Dalfopristin, Danazol, Darunavir, Dasatinib, Daunorubicin, Delavirdine, Desipramine, Dexamethasone, Dextropropoxyphene, Diazepam, Diethylstilbestrol, Dihydroergotamine, Diltiazem, Dimethyl sulfoxide, Docetaxel, Doxorubicin, Doxycycline, Dronedarone, Econazole, Efavirenz, Elbasvir, Enasidenib, Epinephrine, Ergoloid mesylate, Ergonovine, Ergotamine, Erythromycin, Ethanol, Etoposide, Etoricoxib, Ezetimibe, Felodipine, Fentanyl, Fluconazole, Fluoxetine, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Gemfibrozil, Glyburide, Glycerol Phenylbutyrate, Haloperidol, Histamine, Hydralazine, Hydrocortisone, Idelalisib, Ifosfamide, Iloperidone, Imatinib, Indinavir, Irbesartan, Irinotecan, Isavuconazonium, Isoniazid, Isradipine, Itraconazole, Ivacaftor, Josamycin, Ketazolam, Ketoconazole, Lansoprazole, Lapatinib, Lercanidipine, Levofloxacin, Levosalbutamol, Lidocaine, Linagliptin, Lomitapide, Lomustine, Lopinavir, Loratadine, Losartan, Lovastatin, Luliconazole, Lurasidone, Manidipine, Mefloquine, Mequitazine, Methadone, Methazolamide, Methimazole, Methylergometrine, Methylprednisolone, Metronidazole, Metyrapone, Mibefradil, Miconazole, Midazolam, Mifepristone, Mirtazapine, Mitoxantrone, Modafinil, Nefazodone, Nelfinavir, Netupitant, Nevirapine, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nilvadipine, Nisoldipine, Nitrendipine, Nitric Oxide, Norfloxacin, Olanzapine, Olaparib, Omeprazole, Oxybutynin, Oxymetholone, Paclitaxel, Palbociclib, Paramethasone, Pazopanib, Pergolide, Phenelzine, Pilocarpine, Pimozide, Posaconazole, Pravastatin, Prednisolone, Prednisone, Primaquine, Progesterone, Propofol, Quinidine, Quinine, Quinupristin, Rabeprazole, Raloxifene, Ranitidine, Ranolazine, Regorafenib, Repaglinide, Resveratrol, Rilpivirine, Risperidone, Ritonavir, Rivastigmine, Rolitetracycline, Rosuvastatin, Roxithromycin, Rutin, Salbutamol, Saquinavir, Sarilumab, Sertraline, Sildenafil, Simeprevir, Simvastatin, Sirolimus, Sitaxentan, Sorafenib, Stiripentol, Sulfamethoxazole, Sulfanilamide, Sulfinpyrazone, Sulfisoxazole, Tacrolimus, Tadalafil, Tamoxifen, Telaprevir, Telithromycin, Temsirolimus, Teniposide, Terfenadine, Tesmilifene, Testosterone, Tetracycline, Thiopental, Ticagrelor, Ticlopidine, Tioconazole, Tipranavir, Tofisopam, Topiroxostat, Topotecan, Tramadol, Tranylcypromine, Troglitazone, Troleandomycin, Valproic Acid, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinorelbine, Voriconazole, Zafirlukast, Ziprasidone, Zucapsaicin
3Cytochrome P450 3A4 inducersAcetaminophen, Alclometasone, Alimemazine, Aminoglutethimide, Armodafinil, Artemether, Atorvastatin, Azatadine, Bexarotene, Bosentan, Calcitriol, Carbamazepine, Cefradine, Cerivastatin, Chlorphenesin, Clarithromycin, Clevidipine, Clobazam, Clofibrate, Clotrimazole, Clozapine, Colchicine, Cyclophosphamide, Dabrafenib, Deferasirox, Delafloxacin, Desvenlafaxine, Dexamethasone, Dicloxacillin, Drospirenone, Efavirenz, Eletriptan, Enasidenib, Enzalutamide, Eslicarbazepine acetate, Estradiol, Ethanol, Etoposide, Etravirine, Exemestane, Felbamate, Flucloxacillin, Fluorometholone, Fluvastatin, Fosaprepitant, Fosphenytoin, Gemfibrozil, Griseofulvin, Guanethidine, Hydrocortamate, Hydrocortisone, Idelalisib, Ifosfamide, Isavuconazonium, Lansoprazole, Lopinavir, Loratadine, Lumacaftor, Lumefantrine, Medroxyprogesterone acetate, Metamizole, Methadone, Metyrapone, Midostaurin, Mifepristone, Mitotane, Modafinil, Nafcillin, Nevirapine, Nicardipine, Nifedipine, Norgestimate, Omeprazole, Oritavancin, Orlistat, Osimertinib, Oxcarbazepine, Oxiconazole, Paclitaxel, Pantoprazole, Pegvisomant, Pentobarbital, Perampanel, Phenobarbital, Phenylbutazone, Phenytoin, Pioglitazone, Prednisone, Primidone, Probenecid, Progesterone, Pyridostigmine, Quinidine, Quinine, Rifabutin, Rifampicin, Rifapentine, Rifaximin, Rilpivirine, Ritonavir, Rofecoxib, Rufinamide, Seratrodast, Simvastatin, St. John's Wort, Sulfinpyrazone, Tamoxifen, Temozolomide, Terbinafine, Terfenadine, Tesmilifene, Testosterone, Topiramate, Topotecan, Trametinib, Troglitazone
Interacting GroupInteracting Drugs
Vemurafenib is a Multidrug resistance-associated protein 1 substrate
1Multidrug resistance-associated protein 1 inhibitorsAbiraterone, Amprenavir, Atazanavir, Conjugated estrogens, Cyclosporine, Daunorubicin, Diclofenac, Doxorubicin, Etoposide, Genistein, Glutathione, Glyburide, Ibuprofen, Idarubicin, Indinavir, Indomethacin, Ivermectin, Lamivudine, Methotrexate, Mifepristone, Mitoxantrone, Myricetin, Naringenin, Ofloxacin, Paclitaxel, Probenecid, Progesterone, Quercetin, Rifampicin, Ritonavir, Sulfinpyrazone, Taurocholic Acid, Vandetanib, Verapamil, Vinblastine, Vincristine
2Multidrug resistance-associated protein 1 inducersCholic Acid, Phenobarbital, Quercetin, Ritonavir, Taurocholic Acid, Vinblastine
3Multidrug resistance-associated protein 1 substratesAminohippuric acid, Atazanavir, Atorvastatin, Colchicine, Dactinomycin, Daunorubicin, Docetaxel, Doxorubicin, Epirubicin, Etoposide, Fluorescein, Glutathione, Grepafloxacin, Irinotecan, Methotrexate, Mitoxantrone, Rhodamine 6G, Rosuvastatin, Saquinavir, Saxagliptin, Technetium Tc-99m sestamibi, Vinblastine, Vincristine, Zoledronic acid
Interacting GroupInteracting Drugs
Vemurafenib is a Multidrug resistance-associated protein 1 inhibitor
1Multidrug resistance-associated protein 1 inhibitorsAbiraterone, Amprenavir, Atazanavir, Conjugated estrogens, Cyclosporine, Daunorubicin, Diclofenac, Doxorubicin, Etoposide, Genistein, Glutathione, Glyburide, Ibuprofen, Idarubicin, Indinavir, Indomethacin, Ivermectin, Lamivudine, Methotrexate, Mifepristone, Mitoxantrone, Myricetin, Naringenin, Ofloxacin, Paclitaxel, Probenecid, Progesterone, Quercetin, Rifampicin, Ritonavir, Sulfinpyrazone, Taurocholic Acid, Vandetanib, Verapamil, Vinblastine, Vincristine
2Multidrug resistance-associated protein 1 inducersCholic Acid, Phenobarbital, Quercetin, Ritonavir, Taurocholic Acid, Vinblastine
3Multidrug resistance-associated protein 1 substratesAminohippuric acid, Atazanavir, Atorvastatin, Colchicine, Dactinomycin, Daunorubicin, Docetaxel, Doxorubicin, Epirubicin, Etoposide, Fluorescein, Glutathione, Grepafloxacin, Irinotecan, Methotrexate, Mitoxantrone, Rhodamine 6G, Rosuvastatin, Saquinavir, Saxagliptin, Technetium Tc-99m sestamibi, Vinblastine, Vincristine, Zoledronic acid
Interacting GroupInteracting Drugs
Vemurafenib is a ATP-binding cassette sub-family G member 2 substrate
1ATP-binding cassette sub-family G member 2 substratesAbemaciclib, Afatinib, Alvocidib, Apixaban, Camptothecin, Carboplatin, Cerivastatin, Cholesterol, Cisplatin, Cladribine, Clofarabine, Conjugated estrogens, Copanlisib, Dabrafenib, Dactinomycin, Dasatinib, Daunorubicin, Delafloxacin, Docetaxel, Doxorubicin, Enasidenib, Etoposide, Ezetimibe, Fluorouracil, Folic Acid, Gefitinib, Glecaprevir, Glyburide, Idelalisib, Imatinib, Irinotecan, Ivermectin, Lamivudine, Leflunomide, Lenvatinib, Methotrexate, Mitoxantrone, Mycophenolate mofetil, Nilotinib, Nitrofurantoin, Ombitasvir, Osimertinib, Oxaliplatin, Paclitaxel, Pazopanib, Pibrentasvir, Pitavastatin, Ponatinib, Pravastatin, Prazosin, Riluzole, Riociguat, Rosuvastatin, Safinamide, Simeprevir, Sofosbuvir, Sorafenib, Sulfasalazine, Sumatriptan, Tamoxifen, Teniposide, Teriflunomide, Testosterone, Topotecan, Velpatasvir, Venetoclax, Vincristine, Voxilaprevir, Zidovudine
2ATP-binding cassette sub-family G member 2 inhibitorsAbemaciclib, Afatinib, Alectinib, Buprenorphine, Cabazitaxel, Cobicistat, Cyclosporine, Dabrafenib, Daclatasvir, Daidzin, Dasabuvir, Dasatinib, Dexamethasone, Diethylstilbestrol, Doxorubicin, Dronabinol, Elacridar, Enasidenib, Erlotinib, Estradiol, Estrone, Gefitinib, Genistein, Glecaprevir, Glyburide, Hesperetin, Hydrocortisone, Imatinib, Lansoprazole, Mitoxantrone, Naringenin, Nelfinavir, Nilotinib, Novobiocin, Omeprazole, Pantoprazole, Pibrentasvir, Ponatinib, Pravastatin, Prazosin, Quercetin, Rabeprazole, Regorafenib, Rilpivirine, Ritonavir, Rolapitant, Saquinavir, Simeprevir, Sorafenib, Sulfasalazine, Sunitinib, Taurocholic Acid, Telmisartan, Topiroxostat, Topotecan, Vandetanib, Velpatasvir, Verapamil, Vismodegib, Voxilaprevir
3ATP-binding cassette sub-family G member 2 Antagonist sZafirlukast
4ATP-binding cassette sub-family G member 2 inducersVenlafaxine
5ATP-binding cassette sub-family G member 2 weak inhibitorsCobimetinib
6ATP-binding cassette sub-family G member 2 transportersLedipasvir