Showing BioInteractions for Cirazoline (DB09202)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 4

	Interacting Group	Interacting Drugs
	Cirazoline is a Alpha-1A adrenergic receptor agonist
1	Alpha-1A adrenergic receptor agonists	4-Methoxyamphetamine, Apraclonidine, Benzphetamine, Bromocriptine, Clonidine, Dipivefrin, Droxidopa, Ephedrine, Epinephrine, Ergometrine, Isometheptene, Lofexidine, Metaraminol, Methoxamine, Midodrine, Naphazoline, Norepinephrine, Oxymetazoline, Pergolide, Phendimetrazine, Phenylephrine, Pseudoephedrine, Racepinephrine, Tetryzoline, Xylometazoline
2	Alpha-1A adrenergic receptor antagonists	Acepromazine, Alfuzosin, Amitriptyline, Amoxapine, Aripiprazole, Aripiprazole lauroxil, Asenapine, Bevantolol, Bromocriptine, Carvedilol, Chlorpromazine, Clozapine, Dapiprazole, Doxazosin, Doxepin, Dronedarone, Droperidol, Flupentixol, Iloperidone, Imipramine, Indoramin, Methotrimeprazine, Nefazodone, Nicardipine, Nicergoline, Niguldipine, Nortriptyline, Olanzapine, Paliperidone, Phenoxybenzamine, Phentolamine, Pizotifen, Prazosin, Promazine, Propiomazine, Propiverine, Quinidine, Risperidone, Silodosin, Tamsulosin, Terazosin, Thioproperazine, Thioridazine, Tolazoline, Trazodone, Trifluoperazine, Trimipramine, Verapamil, Ziprasidone, Zuclopenthixol
3	Alpha-1A adrenergic receptor partial agonists	Ergotamine
4	Alpha-1A adrenergic receptor potentiators	Carvedilol
5	Alpha-1A adrenergic receptor inhibitors	Amitriptyline, Fenoldopam, Lamotrigine
6	Alpha-1A adrenergic receptor binders	Cabergoline, Loxapine

	Interacting Group	Interacting Drugs
	Cirazoline is a Alpha-1B adrenergic receptor partial agonist
1	Alpha-1B adrenergic receptor antagonists	Acepromazine, Alfuzosin, Amitriptyline, Aripiprazole, Aripiprazole lauroxil, Brexpiprazole, Bromocriptine, Carvedilol, Chlorpromazine, Clozapine, Dapiprazole, Dextroamphetamine, Doxepin, Dronedarone, Imipramine, Methotrimeprazine, Nicardipine, Nortriptyline, Olanzapine, Paliperidone, Periciazine, Phenoxybenzamine, Phentolamine, Pizotifen, Prazosin, Quinidine, Risperidone, Silodosin, Tamsulosin, Terazosin, Thioproperazine, Thioridazine, Trimipramine, Verapamil, Ziprasidone
2	Alpha-1B adrenergic receptor partial agonists	Ergotamine, Modafinil
3	Alpha-1B adrenergic receptor agonists	Bromocriptine, Clonidine, Droxidopa, Epinephrine, Methoxamine, Midodrine, Norepinephrine, Oxymetazoline, Pergolide, Phendimetrazine, Phenylephrine, Racepinephrine, Xylometazoline
4	Alpha-1B adrenergic receptor binders	Cabergoline, Loxapine
5	Alpha-1B adrenergic receptor inhibitors	Fenoldopam

	Interacting Group	Interacting Drugs
	Cirazoline is a Alpha-1D adrenergic receptor partial agonist
1	Alpha-1D adrenergic receptor antagonists	Alfuzosin, Amitriptyline, Carvedilol, Dapiprazole, Doxazosin, Doxepin, Dronedarone, Epinephrine, Imipramine, Methotrimeprazine, Nicardipine, Nortriptyline, Phenoxybenzamine, Phentolamine, Pizotifen, Prazosin, Quinidine, Racepinephrine, Silodosin, Tamsulosin, Terazosin, Verapamil
2	Alpha-1D adrenergic receptor agonists	Bromocriptine, Clonidine, Droxidopa, Midodrine, Norepinephrine, Oxymetazoline, Pergolide, Phenylephrine, Xylometazoline
3	Alpha-1D adrenergic receptor partial agonists	Ergotamine
4	Alpha-1D adrenergic receptor inhibitors	Fenoldopam
5	Alpha-1D adrenergic receptor binders	Cabergoline, Methoxamine

	Interacting Group	Interacting Drugs
	Cirazoline is a Alpha-2 adrenergic receptors antagonist
1	Alpha-2 adrenergic receptors agonists	Bethanidine, Levonordefrin, Pergolide, Tizanidine, Xylazine
2	Alpha-2 adrenergic receptors inhibitors	Chlorpromazine, Escitalopram
3	Alpha-2 adrenergic receptors antagonists	Amoxapine, Dosulepin, Esmirtazapine, Etoperidone, Lorpiprazole, Maprotiline, Nortriptyline, Prochlorperazine, Setiptiline, Tiapride
4	Alpha-2 adrenergic receptors binders	Desipramine, Paroxetine
5	Alpha-2 adrenergic receptors stimulators	Tramadol