Showing BioInteractions for Polaprezinc (DB09221)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Tumor necrosis factor inhibitor | ||
| 1 | Tumor necrosis factor inhibitors | Amrinone, Chloroquine, Infliximab, Pomalidomide, Pseudoephedrine, Thalidomide |
| 2 | Tumor necrosis factor neutralizers | Certolizumab pegol |
| 3 | Tumor necrosis factor antagonists | Epinephrine, Glycyrrhizic acid |
| 4 | Tumor necrosis factor agonists | Epinephrine, Foreskin fibroblast (neonatal), Foreskin keratinocyte (neonatal) |
| 5 | Tumor necrosis factor inducers | Bryostatin 1 |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Interleukin-6 inhibitor | ||
| 1 | Interleukin-6 antagonists | Ginseng, Siltuximab |
| 2 | Interleukin-6 agonists | Foreskin fibroblast (neonatal), Foreskin keratinocyte (neonatal) |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Interleukin-3 inhibitor | ||
| 1 | Interleukin-3 antagonists | Amlexanox |
| 2 | Interleukin-3 binders | Zinc chloride, Zinc sulfate, unspecified form |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Vascular endothelial growth factor receptor 1 agonist | ||
| 1 | Vascular endothelial growth factor receptor 1 inhibitors | Axitinib, Fostamatinib, Lenvatinib, Nintedanib, Pazopanib, Regorafenib, Selpercatinib, Sorafenib, Sunitinib |
| 2 | Vascular endothelial growth factor receptor 1 agonists | Foreskin fibroblast (neonatal) |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Beta-nerve growth factor agonist | ||
| 1 | Beta-nerve growth factor stimulators | Clenbuterol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Platelet-derived growth factor receptor beta agonist | ||
| 1 | Platelet-derived growth factor receptor beta antagonists | Dasatinib, Imatinib, Midostaurin, Sorafenib, Trapidil |
| 2 | Platelet-derived growth factor receptor beta inhibitors | Fostamatinib, Midostaurin, Nintedanib, Pazopanib, Pexidartinib, Pralsetinib, Regorafenib, Ripretinib, Sunitinib |
| 3 | Platelet-derived growth factor receptor beta agonists | Foreskin fibroblast (neonatal) |
| 4 | Platelet-derived growth factor receptor beta substrates | Erdafitinib |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Heat shock protein HSP 90-alpha agonist | ||
| 1 | Heat shock protein HSP 90-alpha inhibitors | Alvespimycin |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Heat shock protein HSP 90-beta agonist | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Superoxide dismutase [Cu-Zn] inducer | ||
| 1 | Superoxide dismutase [Cu-Zn] inducers | alpha-Tocopherol succinate, D-alpha-Tocopherol acetate, Vitamin E |
| 2 | Superoxide dismutase [Cu-Zn] substrates | Cisplatin, Oxaliplatin |
| 3 | Superoxide dismutase [Cu-Zn] inhibitors | Cannabidiol, Carboplatin, Medical Cannabis, Nabiximols |
| 4 | Superoxide dismutase [Cu-Zn] cofactors | Copper, Zinc chloride, Zinc sulfate, unspecified form |
| 5 | Superoxide dismutase [Cu-Zn] ligands | Zinc acetate |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Heme oxygenase 1 inducer | ||
| 1 | Heme oxygenase 1 inducers | alpha-Tocopherol succinate, D-alpha-Tocopherol acetate, Vitamin E |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Superoxide dismutase [Mn], mitochondrial inducer | ||
| 1 | Superoxide dismutase [Mn], mitochondrial activators | Mangafodipir |
| 2 | Superoxide dismutase [Mn], mitochondrial inducers | Thimerosal |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Glutathione S-transferase theta-1 inducer | ||
| 1 | Glutathione S-transferase theta-1 substrates | Carboplatin, Cisplatin, Etoposide, Oxaliplatin |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Glutathione peroxidase 1 inducer | ||
| 1 | Glutathione peroxidase 1 cofactors | Glutathione |
| 2 | Glutathione peroxidase 1 inducers | Medical Cannabis |
| 3 | Glutathione peroxidase 1 ligands | Thimerosal |
| 4 | Glutathione peroxidase 1 activators | Selenious acid |
| 5 | Glutathione peroxidase 1 substrates | Hydrogen peroxide |
| 6 | Glutathione peroxidase 1 stimulators | Cannabidiol, Nabiximols |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Peroxiredoxin-1 inducer | ||
| 1 | Peroxiredoxin-1 ligands | Artenimol |
| 2 | Peroxiredoxin-1 binders | Zinc chloride, Zinc sulfate, unspecified form |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Polaprezinc is a Peroxiredoxin-5, mitochondrial inducer | ||
| 1 | Peroxiredoxin-5, mitochondrial inhibitors | Auranofin |