Showing BioInteractions for Rauwolfia serpentina root (DB09363)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Rauwolfia serpentina root is a Synaptic vesicular amine transporter inhibitor | ||
| 1 | Synaptic vesicular amine transporter inhibitors | 4-Methoxyamphetamine, Amphetamine, Deserpidine, Deutetrabenazine, Ephedra sinica root, Ephedrine, Isometheptene, Metamfetamine, Midomafetamine, MMDA, Reserpine, Tetrabenazine |
| 2 | Synaptic vesicular amine transporter inducers | Apomorphine, Benzphetamine, Dextroamphetamine |
| 3 | Synaptic vesicular amine transporter binders | Norepinephrine |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Rauwolfia serpentina root is a Monoamine oxidase substrate | ||
| 1 | Monoamine oxidase inhibitors | Amphetamine, Procaine, Procarbazine |
| 2 | Monoamine oxidase cofactors | Copper |
| 3 | Monoamine oxidase antagonists | Moclobemide |
| 4 | Monoamine oxidase substrates | Betahistine, Epinephrine, Escitalopram |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Rauwolfia serpentina root is a vesicular monoamine transporter 2 (VMAT2) inhibitor | ||
| 1 | vesicular monoamine transporter 2 (VMAT2) antagonists | Valbenazine |
| 2 | vesicular monoamine transporter 2 (VMAT2) inhibitors | Fostamatinib |