Influenza A virus A/Bolivia/559/2013 (H1N1) live (attenuated) antigen

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Influenza A virus A/Bolivia/559/2013 (H1N1) live (attenuated) antigen
DrugBank Accession Number
DB11034
Background

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". This defence includes the production of humoral immunity through the development of antibodies (through memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus that it was previously exposed to.

There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability.

Type
Biotech
Groups
Approved, Investigational
Biologic Classification
Vaccines
Other vaccines
Synonyms
  • influenza A virus A/Bolivia/559/2013 (H1N1) antigen

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings
Prevent Adverse Drug Events Today
Tap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events with our Clinical API
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!
See the data
Improve decision support & research outcomes with our structured adverse effects data.
See a data sample
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
FluMist QuadrivalentInfluenza A virus A/Bolivia/559/2013 (H1N1) live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza A virus A/New caledonia/71/2014 (H3N2) live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza B virus B/Phuket/3073/2013 live (attenuated) antigen (10000000 [FFU]/0.2mL)SprayNasalMedImmune, LLC2016-07-252016-07-01US flag
FluMist QuadrivalentInfluenza A virus A/Bolivia/559/2013 (H1N1) live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza A virus A/Switzerland/9715293/2013 (H3N2) live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza B virus B/Phuket/3073/2013 live (attenuated) antigen (10000000 [FFU]/0.2mL)SprayNasalMedImmune, LLC2015-08-142016-06-30US flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
6Q05463P25
CAS number
Not Available

References

General References
Not Available
RxNav
1664339

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Active Not RecruitingTreatmentFlu caused by Influenza1
4CompletedPreventionFlu caused by Influenza / Healthy Volunteers (HV)1
2CompletedHealth Services ResearchHuman Immunodeficiency Virus (HIV) Infections1
1WithdrawnPreventionInfluenza, Human1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SprayNasal
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at December 01, 2015 20:05 / Updated at June 12, 2020 16:53