Petrolatum

Identification

Name
Petrolatum
Accession Number
DB11058  (DB09520)
Type
Small Molecule
Groups
Approved
Description

A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.

Synonyms
  • Multi-hydrocarbon
  • Paraffinum album
  • Paraffinum flavum
  • Petrolatum base
  • Petrolatum, white
  • Petrolatum,amber
  • Petrolatum,white
  • Petroleum jelly
  • Soft paraffin
  • White petrolatum
  • White, soft paraffin
  • Yellow soft paraffin
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
A and DOintment937.5 mg/gTopicalH&H Laboratories, Inc.2012-05-14Not applicableUs
A and DOintment937.5 mg/gTopicalHenry Schein2011-12-04Not applicableUs
A and D plus EOintment937.5 mg/gTopicalH&H Laboratories, Inc.2012-05-14Not applicableUs
Advaced First Aid A and DOintment937.5 mg/gTopicalAdvanced First Aid, Inc.2015-04-07Not applicableUs
Advanced HealingOintment340 mg/100gTopicalEquate2013-08-27Not applicableUs
Advanced HealingOintment340 mg/gTopicalBetter Living Brands2015-07-15Not applicableUs
Advanced HealingOintment340 mg/100gTopicalCVS Health2009-01-05Not applicableUs
Advanced HealingOintment340 mg/gTopicalFamily Dollar Services2015-07-15Not applicableUs
Advanced HealingOintment.34 g/gTopicalWalgreen2008-03-28Not applicableUs
Advanced HealingOintment340 mg/100gTopicalKroger2012-11-01Not applicableUs
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
7 Select Hemorrhoidal Original StrengthPetrolatum (749 mg/g) + Mineral oil (140 mg/g) + Phenylephrine hydrochloride (2.5 mg/g)OintmentTopical7 Eleven2016-12-07Not applicableUs
A and D Diaper Rash and Skin ProtectantPetrolatum (.53 mg/g) + Lanolin (.15 mg/g)CreamTopicalNatureplex, LLC2014-11-12Not applicableUs
A and D First AidPetrolatum (469.9 mg/g) + Lanolin (136.4 mg/g)OintmentTopicalBayer2003-06-04Not applicableUs
A and D First AidPetrolatum (469.9 mg/g) + Lanolin (136.4 mg/g)OintmentTopicalFamar Montreal Inc2003-06-042017-05-04Us
A and D OriginalPetrolatum (469.9 mg/g) + Lanolin (136.4 mg/g)OintmentTopicalFamar Montreal Inc2003-06-042017-05-04Us
A and D OriginalPetrolatum (469.9 mg/g) + Lanolin (136.4 mg/g)OintmentTopicalBayer2003-06-04Not applicableUs
A D and L Original Diaper Rash SkinPetrolatum (53.4 g/100g) + Lanolin (15.5 g/100g)OintmentTopicalHarmon Stores2014-09-01Not applicableUs
A+d Diaper Rash OintmentPetrolatum (53.4 %) + Lanolin (15.5 %)OintmentTopicalSchering Plough1998-07-082014-07-31Canada
Alexander's Rash Ease - for BabiesPetrolatum (88.7 %) + Zinc oxide (5 %)CreamTopicalAltacomp Entreprises Inc2010-05-29Not applicableCanada
Alexander's Rash Ease - Sport CreamPetrolatum (88.7 %) + Zinc oxide (5 %)CreamTopicalAltacomp Entreprises IncNot applicableNot applicableCanada
Categories
UNII
4T6H12BN9U
CAS number
8009-03-8
Weight
Not Available
Chemical Formula
Not Available
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

Pharmacology

Indication

For use as an over the counter skin protectant [FDA Label]. Commonly used to treat diaper rash and chapped lips [FDA Label] [1].

Structured Indications
Not Available
Pharmacodynamics

Displaces water and acts as a barrier against harsh environmental conditions like wind [FDA Label] [1].

Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
  1. FDA Monograph: Petrolatum [Link]
External Links
KEGG Drug
D05304
PubChem Substance
347911097
Drugs.com
Drugs.com Drug Page
Wikipedia
Petroleum_jelly
AHFS Codes
  • 84:24.12 — Basic Ointments and Protectants
FDA label
Download (230 KB)
MSDS
Download (47.7 KB)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0CompletedTreatmentIntertrigo1
0WithdrawnTreatmentChemical Peel1
1CompletedNot AvailableHealthy Volunteers1
1, 2TerminatedPreventionRadiodermatitis1
2CompletedTreatmentActinic Keratosis (AK)1
2CompletedTreatmentConjunctivitis, Seasonal Allergic1
2RecruitingPreventionStaphylococcus1
2, 3CompletedTreatmentAbstinence Syndrome / Behavior, Addictive1
3CompletedTreatmentConjunctivitis, Viral1
3CompletedTreatmentEye Dryness1
3Unknown StatusTreatmentAdenovirus / Conjunctivitis1
4CompletedPreventionSkin Diseases1
4CompletedTreatmentConjunctivitis, Seasonal Allergic2
4CompletedTreatmentDiaper Rash1
4CompletedTreatmentDry Eye Syndrome (DES)1
4CompletedTreatmentGlaucoma1
4CompletedTreatmentHypertrophic Scars1
4CompletedTreatmentPityriasis Alba1
4Unknown StatusDiagnosticEye Dryness1
4WithdrawnTreatmentDry Eye Syndrome (DES)1
Not AvailableCompletedPreventionEye Dryness1
Not AvailableCompletedTreatmentCancer, Breast / Radiation Dermatitis1
Not AvailableCompletedTreatmentDry Eye Syndrome (DES)1
Not AvailableCompletedTreatmentEye Dryness1
Not AvailableCompletedTreatmentFoot Eczema / Hand Eczema1
Not AvailableRecruitingNot AvailableBurn Wounds / Chronic / Chronic Wounds / Diabetic Foot Ulcers (DFU) / Pressure Ulcers / Venous Leg Ulcer (VLU) / Wound site1
Not AvailableRecruitingTreatmentAdenoviral Conjunctivitis / Conjunctivitis1
Not AvailableRecruitingTreatmentMigraines1
Not AvailableUnknown StatusTreatmentIntraocular Pressure1
Not AvailableUnknown StatusTreatmentSeborrheic Dermatitis1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
OintmentTopical.34 g/g
OintmentTopical340 mg/100g
OintmentTopical1 g/g
OintmentTopical937.5 mg/g
SprayTopical36 g/100g
OintmentTopical430 mg/g
SprayTopical360 mg/g
JellyTopical99.8 g/100g
OintmentTopical41 %
OintmentTopical540 mg/g
OintmentTopical60.1 %
PasteTopical74.69 %
JellyTopical.99 g/g
OintmentTopical99.93 %
JellyTopical99.7 g/100g
OintmentTopical.511 g/g
OintmentTopical511 mg/g
CreamTopical43 g/1000g
OintmentTopical960 mg/g
PasteTopical
StickTopical
GelTopical
CreamTopical30 %
JellyTopical100 g/100g
JellyTopical99.9 g/100g
OintmentTopical34.85 g/85g
OintmentTopical43.75 mg/g
SalveTopical
CreamTopical.61 g/g
OintmentTopical46.5 g/100g
CreamTopical13.2 %
LipstickTopical619.3 mg/g
StickTopical450 mg/g
StickOral
JellyTopical
JellyTopical998 mg/g
LotionTopical5 g/100g
JellyTopical30 g/100g
JellyTopical.3 mg/100g
JellyTopical.3 g/100g
OintmentTopical710 mg/g
OintmentTopical71.5 %
OintmentTopical98.3 %
CreamTopical300 mg/mL
OintmentTopical410 mg/g
OintmentTopical.041 g/.1g
JellyTopical99 g/100g
JellyTopical98.3 g/100g
CreamTopical85 %
OintmentTopical85 g/100g
OintmentTopical33 g/100g
OintmentTopical44 g/100g
OintmentTopical703.2 mg/g
OintmentTopical30 %
JellyTopical226 g/226g
OintmentTopical41 g/100g
LotionTopical28.4 g/50g
CreamTopical28.4 g/50g
GelTopical1 g/85g
OintmentTopical77.6 g/1000g
OintmentTopical.41 g/g
OintmentRectal; Topical
LipstickTopical
GelTopical70.9787 g/71g
OintmentOphthalmic
OintmentTopical87.32 g/118g
CreamRectal; Topical
OintmentTopical450 mg/mL
CreamTopical
JellyTopical41 g/100g
OintmentTopical340 g/g
OintmentTopical340 mg/g
OintmentTopical41 kg/g
OintmentTopical41 kg/100kg
OintmentTopical46.5 %
StickTopical670 mg/g
OintmentRectal93.3 g/100g
OintmentRectal
OintmentTopical42 g/100g
JellyTopical1000 mg/g
OintmentTopical.76 g/g
LotionTopical
GelTopical99.98 mg/g
CreamTopical430 mg/g
OintmentTopical430 mg/mL
CreamRectal
OintmentTopical95.7 %
OintmentTopical48 g/100mL
StickTopical32.3 g/100g
CreamTopical30 g/100g
StickTopical59.79 %
OintmentTopical76 g/100g
OintmentTopical60.3 %
OintmentTopical604 mg/mL
OintmentTopical60.3 mL/100mL
SprayTopical36 mL/120mL
SprayTopical36 g/120mL
OintmentTopical99.397 g/100g
OintmentTopical774 mg/g
CreamTopical95.96 %
OintmentTopical.41 mg/g
JellyTopical170 g/170g
GelTopical100 g/g
OintmentTopical600 mg/g
JellyTopical1 mg/g
JellyTopical1 g/g
JellyTopical1000 mg/100g
JellyTopical838 g/g
CreamTopical99 g/100g
JellyTopical
OintmentTopical
OintmentTopical99.99 %
JellyTopical100 %
OintmentTopical99.6 %
OintmentTopical99.9 g/100g
JellyTopical100 kg/100kg
CreamTopical67 %
OintmentTopical93.4 g/100g
OintmentTopical75 g/100g
OintmentTopical98.79 %
OintmentTopical.99 g/g
CreamTopical.6 g/g
LiquidTopical
OintmentTopical500 mg/g
PasteTopical59 g/100g
PasteTopical57 g/100g
CreamTopical41 g/100g
JellyTopical410 mg/g
OintmentTopical987.89 mg/g
StickTopical41 mg/g
CreamTopical43 g/100g
LotionTopical39.9 g/133mL
OintmentTopical93.5 g/100g
OintmentTopical23 g/71g
Kit
JellyTopical225 g/225g
JellyTopical110 g/110g
OintmentTopical92.8 %
OintmentTopical92.8 g/100g
OintmentTopical98.3 g/100g
GelOphthalmic
CreamTopical55 %
CreamTopical65 g/100g
JellyTopical99.6 g/100g
OintmentTopical99.96 %
OintmentTopical100 g/100g
GelTopical100 %
JellyTopical99.96 g/100g
OintmentTopical100 %
PatchTopical
OintmentTopical.948 g/g
OintmentTopical.948 mL/mL
OintmentTopical30.8 g/56g
OintmentTopical935 mg/g
OintmentTopical
OintmentTopical929.3 mg/g
OintmentTopical.75 g/g
OintmentTopical.93 g/g
OintmentTopical93 g/100g
LotionTopical.41 g/g
OintmentTopical5 g/1
OintmentTopical50 g/100g
CreamTopical100 %
OintmentTopical99.9 %
OintmentTopical
PasteTopical1000 g
StickTopical30 mg/g
CreamTopical99.7 g/100g
JellyTopical38 g/127g
CreamTopical59 g/198g
Kit
Prices
Not Available
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US8147852No2008-03-302028-03-30Us

Properties

State
Solid
Experimental Properties
PropertyValueSource
melting point (°C)38-60MSDS
water solubilityInsolubleMSDS
Predicted Properties
Not Available
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on December 03, 2015 09:51 / Updated on November 19, 2017 20:34