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IdentificationPharmacologyInteractionsReferencesTrialsEconomicsPropertiesSpectraTaxonomyPetrolatum
Identification
- Name
- Petrolatum
- Accession Number
- DB11058 (DB09520)
- Type
- Small Molecule
- Groups
- Approved, Investigational
- Description
A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
- Synonyms
- Multi-hydrocarbon
- Paraffinum album
- Paraffinum flavum
- Petrolatum base
- Petrolatum, white
- Petrolatum,amber
- Petrolatum,white
- Petroleum jelly
- Soft paraffin
- White petrolatum
- White, soft paraffin
- Yellow soft paraffin
- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End A and D Ointment 937.5 mg/g Topical Henry Schein 2011-12-04 Not applicable US 
A and D Ointment 937.5 mg/g Topical H&H Laboratories, Inc. 2012-05-14 Not applicable US A and D plus E Ointment 937.5 mg/g Topical H&H Laboratories, Inc. 2012-05-14 Not applicable US Advaced First Aid A and D Ointment 937.5 mg/g Topical Advanced First Aid, Inc. 2015-04-07 Not applicable US Advanced Healing Ointment 340 mg/100g Topical Kroger 2012-11-01 Not applicable US Advanced Healing Ointment 340 mg/g Topical Family Dollar Services 2015-07-15 Not applicable US Advanced Healing Ointment 340 mg/100g Topical Walgreen 2013-08-27 Not applicable US Advanced Healing Ointment 340 mg/100g Topical CVS Health 2009-01-05 Not applicable US Advanced Healing Ointment 340 mg/100g Topical Vi Jon 2017-03-20 Not applicable US Advanced Healing Ointment 340 mg/100g Topical Equate 2013-08-27 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End 7 Select Hemorrhoidal Original Strength Petrolatum (749 mg/g) + Mineral oil (140 mg/g) + Phenylephrine hydrochloride (2.5 mg/g) Ointment Topical 7 Eleven 2016-12-07 Not applicable US A and D Diaper Rash and Skin Protectant Petrolatum (.53 mg/g) + Lanolin (.15 mg/g) Cream Topical Natureplex, LLC 2014-11-12 Not applicable US A and D First Aid Petrolatum (469.9 mg/g) + Lanolin (136.4 mg/g) Ointment Topical Bayer 2003-06-04 Not applicable US A and D First Aid Petrolatum (469.9 mg/g) + Lanolin (136.4 mg/g) Ointment Topical Famar Montreal Inc 2003-06-04 2017-05-04 US A and D Original Petrolatum (469.9 mg/g) + Lanolin (136.4 mg/g) Ointment Topical Bayer Health Care Llc. 2003-06-04 Not applicable US A and D Original Petrolatum (469.9 mg/g) + Lanolin (136.4 mg/g) Ointment Topical Famar Montreal Inc 2003-06-04 2017-05-04 US A D and L Original Diaper Rash Skin Petrolatum (53.4 g/100g) + Lanolin (15.5 g/100g) Ointment Topical Harmon Stores 2014-09-01 Not applicable US A+d Diaper Rash Ointment Petrolatum (53.4 %) + Lanolin (15.5 %) Ointment Topical Schering Plough 1998-07-08 2014-07-31 Canada 
Alexander's Rash Ease - for Babies Petrolatum (88.7 %) + Zinc oxide (5 %) Cream Topical Altacomp Entreprises Inc 2010-05-29 Not applicable Canada Alexander's Rash Ease - Sport Cream Petrolatum (88.7 %) + Zinc oxide (5 %) Cream Topical Altacomp Entreprises Inc Not applicable Not applicable Canada - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Premium Scar Patch Petrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (5 g/100g) Patch Topical Alivio Medical Products, Llc 2015-03-15 2017-11-04 US Renuu NL Petrolatum (30 g/100g) + Allantoin (2 g/100g) Patch Topical Patchwerx Labs 2014-04-15 Not applicable US Renuu Patch Petrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (5 g/100g) Patch Topical Patchwerx Labs 2014-04-15 Not applicable US Scar Patch Petrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine hydrochloride (4 g/100g) Patch Topical Binger Consulting Corporation 2014-12-01 2015-11-30 US Scar Patch Petrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (5 g/100g) Patch Topical Binger Consulting Corporation 2014-12-01 2016-10-13 US Vexa Petrolatum (30 mg/1) + Allantoin (2 mg/1) + Lidocaine (4 mg/1) Patch Topical Pharmaceutics Corporation 2015-03-19 2017-10-26 US - Categories
- UNII
- 4T6H12BN9U
- CAS number
- 8009-03-8
- Weight
- Not Available
- Chemical Formula
- Not Available
- InChI Key
- Not Available
- InChI
- Not Available
- IUPAC Name
- Not Available
- SMILES
- Not Available
Pharmacology
- Indication
For use as an over the counter skin protectant [FDA Label]. Commonly used to treat diaper rash and chapped lips [FDA Label] [1].
- Structured Indications
- Not Available
- Pharmacodynamics
Displaces water and acts as a barrier against harsh environmental conditions like wind [FDA Label] [1].
- Mechanism of action
- Not Available
- Absorption
- Not Available
- Volume of distribution
- Not Available
- Protein binding
- Not Available
- Metabolism
- Not Available
- Route of elimination
- Not Available
- Half life
- Not Available
- Clearance
- Not Available
- Toxicity
- Not Available
- Affected organisms
- Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
References
- General References
- FDA Monograph: Petrolatum [Link]
- External Links
- KEGG Drug
- D05304
- PubChem Substance
- 347911097
- Drugs.com
- Drugs.com Drug Page
- Wikipedia
- Petroleum_jelly
- AHFS Codes
- 84:24.12 — Basic Ointments and Protectants
- FDA label
- Download (230 KB)
- MSDS
- Download (47.7 KB)
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 0 Completed Treatment Intertrigo 1 0 Withdrawn Treatment Chemical Peel 1 1 Completed Not Available Healthy Volunteers 1 1, 2 Terminated Prevention Radiodermatitis 1 2 Completed Treatment Actinic Keratosis (AK) 1 2 Completed Treatment Conjunctivitis, Seasonal Allergic 1 2 Recruiting Prevention Staphylococcus 1 2, 3 Completed Treatment Abstinence Syndrome / Behavior, Addictive 1 3 Completed Treatment Conjunctivitis, Viral 1 3 Completed Treatment Eye Dryness 1 3 Unknown Status Treatment Adenovirus / Conjunctivitis 1 4 Completed Prevention Skin Diseases 1 4 Completed Treatment Conjunctivitis, Seasonal Allergic 2 4 Completed Treatment Diaper Rash 1 4 Completed Treatment Dry Eye Syndrome (DES) 1 4 Completed Treatment Glaucoma 1 4 Completed Treatment Hypertrophic Scars 1 4 Completed Treatment Pityriasis Alba 1 4 Unknown Status Diagnostic Eye Dryness 1 4 Withdrawn Treatment Dry Eye Syndrome (DES) 1 Not Available Completed Prevention Eye Dryness 1 Not Available Completed Treatment Cancer, Breast / Radiation Dermatitis 1 Not Available Completed Treatment Dry Eye Syndrome (DES) 1 Not Available Completed Treatment Eye Dryness 1 Not Available Completed Treatment Foot Eczema / Hand Eczema 1 Not Available Completed Treatment Intraocular Pressure 1 Not Available Recruiting Not Available Burn Wounds / Chronic / Chronic Wounds / Diabetic Foot Ulcers (DFU) / Pressure Ulcers / Venous Leg Ulcer (VLU) / Wound site 1 Not Available Recruiting Treatment Adenoviral Conjunctivitis / Conjunctivitis 1 Not Available Recruiting Treatment Migraines 1 Not Available Unknown Status Treatment Seborrheic Dermatitis 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage forms
Form Route Strength Ointment Topical .34 g/g Ointment Topical 340 mg/100g Ointment Topical 1 g/g Ointment Topical 937.5 mg/g Spray Topical 36 g/100g Ointment Topical 430 mg/g Spray Topical 360 mg/g Jelly Topical 99.8 g/100g Ointment Topical 41 % Ointment Topical 540 mg/g Ointment Topical 60.1 % Paste Topical 74.69 % Jelly Topical .99 g/g Ointment Topical 99.93 % Jelly Topical 99.7 g/100g Ointment Topical 84.3 % Ointment Topical .511 g/g Ointment Topical 511 mg/g Cream Topical 43 g/1000g Ointment Topical 960 mg/g Ointment Topical 84.3 g/100g Ointment Topical 620 mg/g Paste Topical Stick Topical Gel Topical Cream Topical 30 % Jelly Topical 100 g/100g Jelly Topical 99.9 g/100g Ointment Topical 34.85 g/85g Ointment Topical 43.75 mg/g Salve Topical Cream Topical .61 g/g Ointment Topical 46.5 g/100g Cream Topical 13.2 % Lipstick Topical 619.3 mg/g Stick Topical 450 mg/g Stick Oral Jelly Topical Jelly Topical 998 mg/g Salve Topical 27.6 g/28.4g Lotion Topical 5 g/100g Jelly Topical 30 g/100g Jelly Topical .3 mg/100g Jelly Topical .3 g/100g Ointment Topical 710 mg/g Ointment Topical 71.5 % Ointment Topical 98.3 % Cream Topical 300 mg/mL Ointment Topical 410 mg/g Ointment Topical .041 g/.1g Jelly Topical 99 g/100g Jelly Topical 98.3 g/100g Cream Topical 85 % Ointment Topical 85 g/100g Ointment Topical 33 g/100g Ointment Topical 44 g/100g Ointment Topical 703.2 mg/g Ointment Topical 30 % Jelly Topical 226 g/226g Ointment Topical 41 g/100g Lotion Topical 28.4 g/50g Cream Topical 28.4 g/50g Gel Topical 1 g/85g Ointment Topical 77.6 g/1000g Ointment Topical .41 g/g Ointment Rectal; Topical Lipstick Topical Gel Topical 70.9787 g/71g Ointment Ophthalmic Ointment Topical 87.32 g/118g Cream Rectal; Topical Ointment Topical 450 mg/mL Cream Topical Jelly Topical 41 g/100g Ointment Topical 340 g/g Ointment Topical 340 mg/g Ointment Topical 41 kg/g Ointment Topical 41 kg/100kg Ointment Topical 46.5 % Stick Topical 670 mg/g Ointment Rectal 93.3 g/100g Ointment Rectal Ointment Topical 42 g/100g Jelly Topical 1000 mg/g Ointment Topical .76 g/g Lotion Topical Gel Topical 99.98 mg/g Cream Topical 430 mg/g Ointment Topical 430 mg/mL Cream Rectal Ointment Topical 95.7 % Ointment Topical 48 g/100mL Stick Topical 32.3 g/100g Cream Topical 30 g/100g Stick Topical 59.79 % Ointment Topical 76 g/100g Ointment Topical 60.3 % Ointment Topical 604 mg/mL Ointment Topical 60.3 mL/100mL Spray Topical 36 mL/120mL Spray Topical 36 g/120mL Ointment Topical 69 % Ointment Topical 99.397 g/100g Ointment Topical 774 mg/g Cream Topical 95.96 % Ointment Topical .41 mg/g Jelly Topical 170 g/170g Gel Topical 100 g/g Cream Topical 69 mg/g Ointment Topical 600 mg/g Jelly Topical 1 g/g Jelly Topical 1 mg/g Jelly Topical 1000 mg/100g Jelly Topical 838 g/g Jelly Topical 99.8 g/100kg Cream Topical 99 g/100g Jelly Topical Ointment Topical Ointment Topical 99.99 % Jelly Topical 100 % Ointment Topical 99.6 % Ointment Topical 99.9 g/100g Jelly Topical 100 kg/100kg Cream Topical 67 % Ointment Topical 93.4 g/100g Ointment Topical 75 g/100g Ointment Topical 98.79 % Ointment Topical .99 g/g Cream Topical .6 g/g Liquid Topical Ointment Topical 500 mg/g Paste Topical 59 g/100g Paste Topical 57 g/100g Cream Topical 41 g/100g Jelly Topical 410 mg/g Ointment Topical 987.89 mg/g Stick Topical 41 mg/g Cream Topical 43 g/100g Lotion Topical 39.9 g/133mL Ointment Topical 93.5 g/100g Ointment Topical 23 g/71g Kit Jelly Topical 225 g/225g Jelly Topical 110 g/110g Ointment Topical 92.8 % Ointment Topical 92.8 g/100g Ointment Topical 98.3 g/100g Gel Ophthalmic Cream Topical 55 % Cream Cutaneous 65 g/100g Jelly Topical 99.6 g/100g Ointment Topical 99.96 % Ointment Topical 100 g/100g Gel Topical 100 % Jelly Topical 99.96 g/100g Patch Topical Ointment Topical .948 g/g Ointment Topical .948 mL/mL Ointment Topical 30.8 g/56g Ointment Topical 935 mg/g Ointment Topical Ointment Topical 929.3 mg/g Ointment Topical .75 g/g Ointment Topical .93 g/g Ointment Topical 93 g/100g Lotion Topical .41 g/g Ointment Topical 5 g/1 Ointment Topical 50 g/100g Ointment Topical 100 % Cream Topical 100 % Ointment Topical 99.9 % Ointment Topical Paste Topical 1000 g Ointment Topical 1000 mg/g Stick Topical 30 mg/g Cream Topical 99.7 g/100g Jelly Topical 38 g/127g Cream Topical 59 g/198g Kit - Prices
- Not Available
- Patents
Patent Number Pediatric Extension Approved Expires (estimated) US8147852 No 2008-03-30 2028-03-30 US
Properties
- State
- Solid
- Experimental Properties
Property Value Source melting point (°C) 38-60 MSDS water solubility Insoluble MSDS - Predicted Properties
- Not Available
- Predicted ADMET features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Taxonomy
- Classification
- Not classified
Drug created on December 03, 2015 09:51 / Updated on April 23, 2018 23:14