Petrolatum

Identification

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Name
Petrolatum
Accession Number
DB11058  (DB09520)
Type
Small Molecule
Groups
Approved, Investigational
Description

A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.

Synonyms
  • Multi-hydrocarbon
  • Paraffinum album
  • Paraffinum flavum
  • Petrolatum base
  • Petrolatum, white
  • Petrolatum,amber
  • Petrolatum,white
  • Petroleum jelly
  • Soft paraffin
  • White petrolatum
  • White, soft paraffin
  • Yellow soft paraffin
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
A and DOintment937.5 mg/1gTopicalH&H Laboratories, Inc.2012-05-14Not applicableUs
A and DOintment937.5 mg/1gTopicalHenry Schein2011-12-04Not applicableUs
A and D plus EOintment937.5 mg/1gTopicalH&H Laboratories, Inc.2012-05-14Not applicableUs
Advaced First Aid A and DOintment937.5 mg/1gTopicalAdvanced First Aid, Inc.2015-04-07Not applicableUs
Advanced HealingOintment340 mg/1gTopicalBetter Living Brands LLC2015-07-15Not applicableUs
Advanced HealingOintment340 mg/100gTopicalAmazon.Com., Inc2017-08-27Not applicableUs
Advanced HealingOintment340 mg/1gTopicalFamily Dollar Services Inc2015-07-15Not applicableUs
Advanced HealingOintment0.340 g/1gTopicalWalgreen2008-03-28Not applicableUs
Advanced HealingOintment340 mg/100gTopicalKroger2012-11-01Not applicableUs
Advanced HealingOintment340 mg/100gTopicalCVS Pharamacy, Inc2009-01-05Not applicableUs
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
7 Select Hemorrhoidal Original StrengthPetrolatum (749 mg/1g) + Mineral oil (140 mg/1g) + Phenylephrine hydrochloride (2.5 mg/1g)OintmentTopical7-ELEVEN, INC.2016-12-07Not applicableUs
A and D Diaper Rash and Skin ProtectantPetrolatum (0.53 mg/1g) + Lanolin (0.15 mg/1g)CreamTopicalNatureplex, LLC2014-11-12Not applicableUs
A and D First AidPetrolatum (469.9 mg/1g) + Lanolin (136.4 mg/1g)OintmentTopicalBayer2003-06-04Not applicableUs
A and D First AidPetrolatum (469.9 mg/1g) + Lanolin (136.4 mg/1g)OintmentTopicalFamar Montreal Inc2003-06-04Not applicableUs
A and D OriginalPetrolatum (469.9 mg/1g) + Lanolin (136.4 mg/1g)OintmentTopicalBayer Healthcare Llc.2003-06-04Not applicableUs
A and D OriginalPetrolatum (469.9 mg/1g) + Lanolin (136.4 mg/1g)OintmentTopicalFamar Montreal Inc2003-06-04Not applicableUs
A D and L Original Diaper Rash SkinPetrolatum (53.4 g/100g) + Lanolin (15.5 g/100g)OintmentTopicalHarmon Stores2014-09-01Not applicableUs
A+d Diaper Rash OintmentPetrolatum (53.4 %) + Lanolin (15.5 %)OintmentTopicalSchering Plough1998-07-082014-07-31Canada
Alexander's Rash Ease - for BabiesPetrolatum (88.7 %) + Zinc oxide (5 %)CreamTopicalAltacomp Entreprises Inc2010-05-29Not applicableCanada
Alexander's Rash Ease - Sport CreamPetrolatum (88.7 %) + Zinc oxide (5 %)CreamTopicalAltacomp Entreprises IncNot applicableNot applicableCanada
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
AntiscarPetrolatum (3 g/100g) + 13-cis-12-(3'-Carboxyphenyl)retinoic acid (2 g/100g) + Allantoin (2 g/100g) + Epigallocatechin gallate (.3 g/100g) + Onion (.5 g/100g)PatchTopicalBasiem2015-04-012015-04-20Us
ElitePetrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (4 g/100g)PatchTopicalMeds Direct Rx Of Ny Llc2015-01-312015-06-08Us
PCP 100 KitPetrolatum (0.76 g/1g) + Bisacodyl (5 mg/1) + Magnesium citrate (1.745 g/29.6mL) + Metoclopramide hydrochloride monohydrate (10 mg/1) + Polyethylene glycol (17 g/17g)KitOral; TopicalAsclemed Usa, Inc.2014-01-02Not applicableUs
PreginotPetrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (4 g/100g)PatchTopicalPharmaco Technology Llc2015-04-012015-04-01Us
Premium Scar PatchPetrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (5 g/100g)PatchTopicalAlivio Medical Products, Llc2015-03-15Not applicableUs
Renuu NLPetrolatum (30 g/100g) + Allantoin (2 g/100g)PatchTopicalPatchwerx Labs2014-04-15Not applicableUs
Renuu PatchPetrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (5 g/100g)PatchTopicalPatchwerx Labs2014-04-15Not applicableUs
Scar PatchPetrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine (5 g/100g)PatchTopicalBinger Consulting Corporation2014-12-012016-07-31Us
Scar PatchPetrolatum (30 g/100g) + Allantoin (2 g/100g) + Lidocaine hydrochloride (4 g/100g)PatchTopicalBinger Consulting Corporation2014-12-012015-11-30Us
VexaPetrolatum (30 mg/1) + Allantoin (2 mg/1) + Lidocaine (4 mg/1)PatchTopicalPharmaceutics Corporation2015-03-19Not applicableUs
Categories
UNII
4T6H12BN9U
CAS number
8009-03-8
Weight
Not Available
Chemical Formula
Not Available
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

Pharmacology

Indication

For use as an over the counter skin protectant Label. Commonly used to treat diaper rash and chapped lips Label 1.

Associated Therapies
Pharmacodynamics

Displaces water and acts as a barrier against harsh environmental conditions like wind Label 1.

Mechanism of action
Not Available
Additional Data Available
Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
  1. FDA Monograph: Petrolatum [Link]
External Links
KEGG Drug
D05304
PubChem Substance
347911097
Wikipedia
Petroleum_jelly
AHFS Codes
  • 84:24.12 — Basic Ointments and Protectants
FDA label
Download (230 KB)
MSDS
Download (47.7 KB)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0CompletedTreatmentIntertrigo1
0WithdrawnTreatmentChemical Peel1
1CompletedNot AvailableHealthy Volunteers1
1CompletedTreatmentHealthy Volunteers1
1, 2TerminatedPreventionRadiodermatitis1
2CompletedTreatmentActinic Keratosis (AK)1
2CompletedTreatmentConjunctivitis, Seasonal Allergic1
2Not Yet RecruitingTreatmentBack Pain / Endometriosis / Fibromyalgia Syndrome / Interstitial Cystitis / Irritable Bowel Syndrome (IBS) / Migraine / Myalgic Encephalomyelitis (ME) / Temporomandibular Disorders / Tension Headache / Vestibulodynia1
2RecruitingPreventionStaphylococcus1
2, 3CompletedTreatmentAbstinence Syndrome / Behavior, Addictive1
3Active Not RecruitingTreatmentAdvanced Malignancies / Carcinoma NOS / Lung Cancer Non-Small Cell Cancer (NSCLC) / Lung Cancers1
3CompletedTreatmentConjunctivitis, Viral1
3CompletedTreatmentEye Dryness1
3Unknown StatusTreatmentAdenovirus / Conjunctivitis1
4Active Not RecruitingTreatmentType 2 Diabetes Mellitus / Xerosis Cutis1
4CompletedPreventionSkin Diseases1
4CompletedTreatmentConjunctivitis, Seasonal Allergic1
4CompletedTreatmentDiaper Rash1
4CompletedTreatmentHypertrophic Scars1
4CompletedTreatmentPityriasis Alba1
4RecruitingTreatmentAtopic Dermatitis (AD) / Dermatitis, Eczematous1
4RecruitingTreatmentCystic Fibrosis (CF) / Iron-Deficiency1
4Unknown StatusDiagnosticEye Dryness1
4WithdrawnTreatmentDry Eye Syndrome (DES)1
Not AvailableCompletedPreventionEye Dryness1
Not AvailableCompletedTreatmentCancer, Breast / Radiation Dermatitis1
Not AvailableCompletedTreatmentDry Eye Syndrome (DES)1
Not AvailableCompletedTreatmentEye Dryness1
Not AvailableCompletedTreatmentFoot Eczema / Hand Eczema1
Not AvailableCompletedTreatmentGastroenteritis / Severe or persistent diarrhea1
Not AvailableCompletedTreatmentIntraocular Pressure1
Not AvailableRecruitingNot AvailableBurn Wounds / Chronic / Chronic Wounds / Diabetic Foot Ulcers (DFU) / Pressure Ulcers / Venous Leg Ulcer (VLU) / Wound site1
Not AvailableRecruitingPreventionKidney Transplant; Complications1
Not AvailableRecruitingTreatmentAdenoviral Conjunctivitis / Conjunctivitis1
Not AvailableTerminatedTreatmentMigraine1
Not AvailableUnknown StatusTreatmentSeborrheic Dermatitis1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
OintmentTopical937.5 mg/1g
OintmentTopical0.340 g/1g
OintmentTopical340 mg/100g
SprayTopical36 g/100g
OintmentTopical430 mg/1g
SprayTopical360 mg/1g
JellyTopical99.8 g/100g
JellyTopical99.5 g/100g
OintmentTopical100 g/44.28g
OintmentTopical41 %
OintmentTopical540 mg/1g
OintmentTopical54 mg/1g
StickTopical
OintmentTopical60.1 %
PasteTopical74.69 %
CreamTopical99 g/100g
OintmentTopical99.93 %
OintmentTopical84.3 g/100g
OintmentTopical84.3 %
OintmentTopical0.511 g/1g
OintmentTopical511 mg/1g
CreamTopical43 g/1000g
OintmentTopical960 mg/1g
OintmentTopical620 mg/1g
CreamTopical30 %
OintmentTopical34.85 g/85g
StickTopical41 mg/1g
OintmentTopical43.75 mg/1g
OintmentTopical.96 g/1g
SalveTopical
CreamTopical0.61 g/1g
OintmentTopical46.5 g/100g
CreamTopical13.2 %
LipstickTopical619.3 mg/1g
StickTopical450 mg/1g
Kit
StickOral
JellyTopical
JellyTopical1 g/1g
JellyTopical998 mg/1g
SalveTopical27.6 g/28.4g
LotionTopical5 g/100g
JellyTopical30 g/100g
JellyTopical.30 g/100g
JellyTopical.30 mg/100g
CreamTopical30 g/100g
OintmentTopical710 mg/1g
OintmentTopical71.5 %
OintmentTopical865 mg/1g
OintmentTopical98.3 %
PasteTopical
CreamTopical300 mg/1mL
OintmentTopical410 mg/1g
OintmentTopical.041 g/.1g
CreamTopical33 g/100g
JellyTopical99 g/100g
JellyTopical98.3 g/100g
CreamTopical85 %
OintmentTopical85 g/100g
OintmentTopical33 g/100g
OintmentTopical44 g/100g
OintmentTopical713 mg/1g
OintmentTopical703.2 mg/1g
OintmentTopical30 %
OintmentTopical
JellyTopical226 g/226g
LotionTopical28.4 g/50g
CreamTopical28.4 g/50g
GelTopical1 g/85g
OintmentTopical600 g/1000g
OintmentTopical77.6 g/1000g
OintmentTopical0.41 g/1g
StickTopical45.0 mg/1g
LipstickTopical
GelTopical70.9787 g/71g
OintmentTopical87.32 g/118g
OintmentTopical0.93 g/1g
CreamRectal; Topical
OintmentTopical450 mg/1mL
CreamTopical50.74 g/100g
OintmentTopical340 g/1g
OintmentTopical340 mg/1g
OintmentTopical41 kg/1g
OintmentTopical41 kg/100kg
OintmentTopical46.5 %
StickTopical670 mg/1g
OintmentRectal93.3 g/100g
OintmentTopical41.000 g/100g
OintmentOphthalmic
CreamTopical52.2 g/100g
LotionTopical
CreamTopical430 mg/1g
OintmentTopical430 mg/1mL
OintmentTopical95.7 %
OintmentTopical76 g/100g
OintmentTopical48 g/100mL
StickTopical32.3 g/100g
JellyTopical1000 mg/1g
StickTopical59.79 %
OintmentRectal; Topical
OintmentTopical60.3 %
OintmentTopical604 mg/1mL
OintmentTopical60.3 mL/100mL
SprayTopical36 g/120mL
SprayTopical36 mL/120mL
OintmentTopical69 %
OintmentTopical99.397 g/100g
OintmentTopical99.9 g/100g
OintmentTopical774 mg/1g
CreamTopical95.96 %
OintmentTopical0.41 mg/1g
KitOral; Topical
OintmentTopical49.9 g/1g
JellyTopical170 g/170g
GelTopical100 g/1g
CreamTopical69 mg/1g
OintmentTopical600 mg/1g
JellyTopical1 mg/1g
JellyTopical100 g/100g
JellyTopical1000 mg/100g
JellyTopical838 g/1g
JellyTopical99.8 g/100kg
JellyTopical
OintmentTopical
OintmentTopical99.99 %
JellyTopical99.9 g/100g
JellyTopical99.9 1/100g
JellyTopical100 %
OintmentTopical99.6 %
Paste650 mg/1mL
CreamTopical67 %
OintmentTopical93.4 g/100g
OintmentTopical75 g/100g
OintmentTopical98.79 %
OintmentTopical0.99 g/1g
CreamTopical0.6 g/1g
JellyTopical0.99 g/1g
LiquidTopical
OintmentTopical500 mg/1g
PasteTopical57 g/100g
CreamTopical41 g/100g
JellyTopical410 mg/1g
OintmentTopical41 g/100g
OintmentTopical420 mg/1g
JellyTopical41.0 g/100g
CreamTopical
OintmentTopical987.89 mg/1g
CreamRectal
GelTopical99.98 mg/1g
CreamTopical43 g/100g
LotionTopical39.9 g/133mL
OintmentTopical93.5 g/100g
OintmentTopical23 g/71g
JellyTopical225 g/225g
JellyTopical110 g/110g
OintmentTopical92.8 %
OintmentTopical92.8 g/100g
OintmentTopical98.3 g/100g
PasteTopical59 g/100g
GelOphthalmic
CreamTopical55 %
JellyTopical99.7 g/100g
CreamCutaneous65 g/100g
OintmentRectal
JellyTopical99.6 g/100g
OintmentTopical99.96 %
OintmentTopical100 g/100g
GelTopical100 %
GelTopical
JellyTopical99.96 g/100g
PatchTopical
OintmentTopical.948 g/1g
OintmentTopical.948 mL/1mL
OintmentTopical0.948 mL/1mL
OintmentTopical30.8 g/56g
OintmentTopical935 mg/1g
OintmentTopical929.3 mg/1g
OintmentTopical.75 g/1g
OintmentTopical.76 g/1g
OintmentTopical.93 g/1g
OintmentTopical0.76 g/1g
OintmentTopical93 g/100g
LotionTopical0.41 g/1g
OintmentTopical42 g/100g
OintmentTopical1 g/1g
OintmentTopical50 g/100g
OintmentTopical100 %
CreamTopical100 %
OintmentTopical99.9 %
PasteTopical1000 g
OintmentTopical1000 mg/1g
StickTopical30.0 mg/1g
CreamTopical99.7 g/100g
JellyTopical38 g/127g
CreamTopical59 g/198g
Prices
Not Available
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US8147852No2012-04-032028-03-30Us
Additional Data Available
  • Filed On
    Filed On

    The date on which a patent was filed with the relevant government.

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Properties

State
Solid
Experimental Properties
PropertyValueSource
melting point (°C)38-60MSDS
water solubilityInsolubleMSDS
Predicted Properties
Not Available
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on December 03, 2015 09:51 / Updated on June 18, 2019 01:48