Identification
- Summary
Shark liver oil is an ingredient used to treat irritation associated with hemorrhoids and is not an approved medication.
- Generic Name
- Shark liver oil
- DrugBank Accession Number
- DB11088
- Background
Shark oil is extracted from the livers of sharks, which can account for up to 25% of their total body weight. The 3 main targeted species are the deep sea shark (Centrophorus squamosus), the dogfish (Sqaulus acanthias), and the basking shark (Cetorhinus maximus). Shark oil is a rich source of alkylglycerols and squalene, with relatively low amounts of n-3 polyunsaturated fatty acids. However the major component is considered to be squalene, which may range up to 90% of the shark oil, depending on the species. The potential benefit of shark oil has been experimented in different therapeutic implications, where it is claimed to improve immune responses and exert an antitumor activity.
- Type
- Biotech
- Groups
- Experimental
- Synonyms
- Not Available
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Care One Hemorrhoidal Shark liver oil (6.375 mg/1) + Cocoa butter (2137.5 mg/1) + Phenylephrine hydrochloride (75 mg/1) Suppository Rectal American Sales Company 2003-12-09 2015-09-01 US 
Care One Hemorrhoidal Shark liver oil (3 g/100g) + Mineral oil (14 g/100g) + Petrolatum (71.9 g/100g) + Phenylephrine hydrochloride (0.25 g/100g) Ointment Topical American Sales Company 2004-03-16 2014-08-30 US Cocoa Butter, Phenylephrine Hydrochloride, Shark Liver Oil Shark liver oil (73 mg/1) + Cocoa butter (2077 mg/1) + Phenylephrine hydrochloride (6 mg/1) Suppository Rectal H and P Industries, Inc. dba Triad Group 2004-03-06 Not applicable US DG Health Hemorrhoidal Shark liver oil (3 g/100g) + Mineral oil (14 g/100g) + Petrolatum (71.9 g/100g) + Phenylephrine hydrochloride (0.25 g/100g) Ointment Topical Dolgencorp 2010-05-22 2014-10-16 US Equaline Hemorrhoidal Shark liver oil (6.375 mg/1) + Cocoa butter (2137.5 mg/1) + Phenylephrine hydrochloride (75 mg/1) Suppository Rectal Supervalu 2004-09-23 2015-09-01 US
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 4B24275HEU
- CAS number
- 68990-63-6
References
- General References
- Lewkowicz N, Lewkowicz P, Kurnatowska A, Tchorzewski H: [Biological action and clinical application of shark liver oil]. Pol Merkur Lekarski. 2006 May;20(119):598-601. [Article]
- External Links
- PubChem Substance
- 347911111
- 91472
- Wikipedia
- Shark_liver_oil
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Ointment Rectal; Topical Suppository Rectal Ointment Topical 14 % Suppository Rectal 85.5 % Ointment Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Liquid
- Experimental Properties
- Not Available
Drug created at December 03, 2015 16:51 / Updated at June 12, 2020 16:53