Allantoin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Allantoin
Accession Number
DB11100
Type
Small Molecule
Groups
Approved
Description

Allantoin is a diureide of glyoxylic acid that is produced from uric acid. It is a major metabolic intermediate in most organisms. Allantoin is found in OTC cosmetic products and other commercial products such as oral hygiene products, in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions. Allantoin has also demonstrated to ameliorate the wound healing process.

Structure
Thumb
Synonyms
  • 5-ureidohydantoin
  • glyoxyldiureide
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Elta Dermal Gel for Wound DressingGel2 %TopicalSwiss American ProductsNot applicableNot applicableCanada
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
12 Hour HealingOintment.5 g/100gTopicalSkinfix, Inc.2017-05-02Not applicableUs
12 Hour MiracleOintment.5 g/100gTopicalSkinfix, Inc.2015-05-23Not applicableUs
AAFX HairSolution.02 mg/71TopicalProstemics Co., Ltd.2014-12-01Not applicableUs
AAFX SkinSolution.02 mg/71TopicalProstemics Co., Ltd.2014-12-01Not applicableUs
AAPE Hair AmpouleSolution.03 mg/61TopicalProstemics Co., Ltd.2014-08-01Not applicableUs
AAPE Skin AmpouleSolution.03 mg/61TopicalProstemics Co., Ltd.2014-08-01Not applicableUs
Actifirm Recovery Eye Gowoonsesang ExpertCream.1 mL/20mLCutaneousGOWOONSESANG COSMETICS CO., LTD.2010-06-01Not applicableUs
AllantoinAerosol, spray.425 g/85gTopicalCvs Health2015-04-15Not applicableUs
AllantoinSpray.425 g/85gTopicalHarmon Store Inc.2015-09-04Not applicableUs
Aloe Propolis SoothingGel.15 g/30mLTopicalBenton Inc.2016-09-01Not applicableUs
Unapproved/Other Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
28 Remedy Aqua Brightening PeelingGel.05 g/100mLTopicalNo Ts Co.,Ltd2016-01-02Not applicableUs
3ce Fixer and Mascara BlackLiquid.006 g/6.6gTopicalNanda Co., Ltd.2016-08-20Not applicableUs
3ce Fixer and Mascara BrownLiquid.006 g/6.6gTopicalNanda Co., Ltd.2016-08-20Not applicableUs
AC Control SerumCream.1 g/50mLTopicalMiguhara2016-01-02Not applicableUs
Atorak AmpouleSolution.005 mg/181TopicalDasan E&T Co., Ltd.2015-03-01Not applicableUs
BABOR CLEANSING Rose ToningLotion.4 mL/200mLTopicalBabor Cosmetics America, Corp.2004-04-152017-07-15Us
BABOR Collagen BoosterLiquid.004 mL/2mLTopicalBabor Cosmetics America, Corp.2007-05-012017-07-15Us
bdr Re-fresh gel mask facePatch.12 g/60gTopicalHanaim International Llc2016-11-18Not applicableUs
Beauty Fox AtoclinicLotion.25 g/250gTopicalBeauty Fox Co., Ltd.2015-09-30Not applicableUs
BK Cell 2STEP AQUA TOKTOK MASKPatch.004 g/2.4gTopicalBnk Co., Ltd.2015-08-01Not applicableUs
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
3M Nexcare Cold Sore TreatmentAllantoin (10 mg/g) + Benzocaine (50 mg/g)OintmentTopical3 M Pharmaceuticals2008-02-20Not applicableUs
4JointzAllantoin (.025 g/100g) + Eucalyptus oil (4 g/100g) + Tannic acid (5 g/100g)CreamTopicalArp(usa) Pty Ltd2017-01-31Not applicableUs
A.H.c Cotton 100 Mask Multi PeptideAllantoin (.025 g/25mL) + Adenosine (.01 g/25mL) + Nicotinamide (.05 g/25mL)PatchTopicalCarver Korea Co.,Ltd.2017-09-20Not applicableUs
A.H.c Cotton 100 Mask Skin CeramideAllantoin (.025 g/25mL) + Adenosine (.01 g/25mL) + Nicotinamide (.05 g/25mL)PatchTopicalCarver Korea Co.,Ltd.2017-09-05Not applicableUs
A.H.c Cotton 100 Mask Soy IsoflavoneAllantoin (.025 g/25mL) + Adenosine (.01 g/25mL) + Nicotinamide (.05 g/25mL)PatchTopicalCarver Korea Co.,Ltd.2017-09-14Not applicableUs
A.H.c Cotton 100 Mask Triple HyaluronicAllantoin (.025 g/25mL) + Adenosine (.01 g/25mL) + Nicotinamide (.05 g/25mL)PatchTopicalCarver Korea Co.,Ltd.2017-09-20Not applicableUs
Actinac PwrAllantoin (24 mg) + Chloramphenicol (40 mg) + Hydrocortisone acetate (40 mg) + Nicoboxil (24 mg) + Sulfur (320 mg)PowderTopicalRoussel Canada Inc.1978-12-311996-09-09Canada
Actinac PwsAllantoin (24 mg) + Chloramphenicol (40 mg) + Hydrocortisone acetate (40 mg) + Nicoboxil (24 mg) + Sulfur (320 mg)Powder, for solutionTopicalHoechst Roussel Canada Inc.1994-12-312001-07-20Canada
Ahc Radiance Gommage PeelingAllantoin (1 g/100mL) + Dexpanthenol (1 g/100mL)GelTopicalCarver Korea Co.,Ltd.2017-05-10Not applicableUs
AL0040600 Alba Cooling Aloe Burn ReliefAllantoin (.5 g/100g) + Menthol (.5 g/100g)SprayTopicalThe Hain Celestial Group2016-01-13Not applicableUs
Categories
UNII
344S277G0Z
CAS number
97-59-6
Weight
Not Available
Chemical Formula
Not Available
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

Pharmacology

Indication
Not Available
Structured Indications
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
  1. Araujo LU, Grabe-Guimaraes A, Mosqueira VC, Carneiro CM, Silva-Barcellos NM: Profile of wound healing process induced by allantoin. Acta Cir Bras. 2010 Oct;25(5):460-6. [PubMed:20877959]
External Links
Not Available
AHFS Codes
  • 84:06.00 — Anti-inflammatory Agents
  • 84:04.04 — Antibiotics
  • 84:08.00 — Antipruritics and Local Anesthetics
  • 84:24.12 — Basic Ointments and Protectants
  • 92:01.00* — Herbs and Natural Products
  • 84:28.00 — Keratolytic Agents
  • 84:32.00 — Keratoplastic Agents
  • 84:04.08.92 — Miscellaneous Antifungals
  • 84:04.92 — Miscellaneous Local Anti-infectives
  • 84:80.00 — Sunscreen Agents

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedTreatmentEpidermolysis Bullosa1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
LiquidTopical.006 g/6.6g
OintmentTopical
SolutionTopical.02 mg/71
SolutionTopical.03 mg/61
CreamTopical.1 g/50mL
CreamCutaneous.1 mL/20mL
Powder, for solutionTopical
Aerosol, sprayTopical.425 g/85g
SprayTopical.425 g/85g
GelTopical.5 g/100mL
GelTopical.15 g/30mL
CreamTopical.0005 g/mL
OintmentTopical.5 g/100g
CreamTopical.8 mg/160mL
LotionTopical.8 mg/160mL
GelTopical.8 mg/160mL
ShampooTopical1.5 mg/300mL
SolutionTopical.005 mg/181
SprayTopical
LotionTopical.4 mL/200mL
LiquidTopical.004 mL/2mL
PatchTopical.12 g/60g
ElixirTopical
EmulsionTopical0.6 %
LotionTopical.25 g/250g
CreamCutaneous.2 g/40g
PatchTopical.15 g/31
GelTopical.15 g/31
PatchTopical.004 g/2.4g
EmulsionTopical.1 g/100mL
PatchTopical.2 g/40g
LiquidTopical.0005 g/mL
StickTopical5 mg/g
LiquidTopical.15 g/100mL
GelTopical.75 g/75g
CreamTopical.225 mg/45mL
SprayTopical.6 mg/120mL
CreamTopical.22 mg/45mL
CreamTopical2 g/100g
PatchTopical.5 1/25g
PatchTopical.06 g/51
LiquidTopical.1 g/100mL
CreamTopical.5 mg/100g
CreamTopical5 mg/g
JellyTopical.5 g/100mL
LotionTopical.5 g/100mL
CreamTopical50 mg/5g
LipstickTopical
CreamTopical.5 mL/100mL
PowderTopical.02 g/50g
CreamTopical.5 g/100g
DiscTopical
Paste, dentifriceDental
EmulsionTopical
CreamTopical3.6 mL/60mL
LotionTopical.5 1/50mL
CreamTopical.5 mg/100mL
GelTopical.05 g/100g
CreamTopical.1 g/100g
LiquidTopical.05 g/100mL
LiquidTopical.2 g/100mL
CreamCutaneous
PatchTopical.1 g/49g
ShampooTopical6 g/300mL
LotionTopical
LotionTopical.75 mg/150mL
GelTopical2 %
LotionTopical2 %
GelTopical.1 g/100mL
CreamTopical1 g/50g
SprayTopical.3 g/60g
SprayTopical1.2 g/100g
Tablet, solubleTopical.5 mg/100mg
LiquidTopical.19 g/100g
CreamTopical.1 g/100mL
PowderTopical.44 mg/80mL
PowderTopical.055 g/10g
GelTopical.8 g/100g
LotionTopical.4 g/20mL
SoapTopical2 g/100g
LiquidTopical.54 mg/90mL
SolutionTopical.96 g/120mL
SolutionTopical.96 mg/120mL
SolutionTopical
LiquidTopical.1 g/10g
GelTopical.5 g/100g
OintmentTopical.02 g/g
SolutionTopical.04 g/5g
LotionTopical3 g/600g
LotionCutaneous.1 mL/20mL
SoapCutaneous; Topical5 mg/g
PowderTopical.002 g/g
SolutionTopical.25 g/205g
TabletVaginal.2 1/1
TabletVaginal66 mg/600mg
GelTopical51 mg/10mL
GelTopical50 mg/10mL
CreamTopical.67 mg/135mL
CreamTopical.25 mg/50mL
PatchTopical.2 g/100g
CreamTopical1 g/100mL
GelTopical10 mg/mL
GelTopical.1 mg/mL
GelTopical5 mg/g
GelTopical10 mg/g
TabletVaginal.11 1/600mg
StickTopical
LotionTopical0.55 %
PatchTopical.17 mg/35mL
SoapTopical.6 g/100g
LiquidTopical.01 g/100mL
OintmentTopical1 %
GelTopical
CreamTopical.075 g/15mL
LiquidTopical1 mg/30mL
LiquidTopical.08 g/100mL
LiquidTopical.75 mg/150mL
PatchTopical.028 g/28g
SprayTopical.3 mg/60mL
CreamTopical
LiquidTopical.6 mg/30mL
LiquidTopical.54 mg/30mL
SoapTopical.55 g/110g
GelTopical3 mg/mL
LiquidTopical.05 g/10mL
ShampooTopical.75 g/150mL
SolutionTopical.3 g/60mL
LiquidTopical.025 g/5mL
SoapTopical1.3 g/100g
Aerosol, foamTopical1.25 mg/250mL
OilTopical.75 mg/150mL
SolutionTopical.1 g/100mL
LiquidTopical.002 g/mL
EmulsionTopical.002 g/mL
LiquidTopical2 g/100mL
LotionTopical.1 mL/50mL
LiquidTopical.02 mg/mL
LiquidTopical.1 g/100g
LiquidTopical1 g/100mL
GelTopical.05 g/100mL
CreamTopical.25 g/50g
ShampooTopical.75 mg/150mL
SolutionTopical.3 mg/60mL
LiquidTopical.025 mg/5mL
LiquidTopical.3 g/100mL
SolutionTopical.175 mg/51
PatchTopical.16 g/32g
LotionTopical.1 g/100mL
PatchTopical.015 mg/101
SprayTopical.1 g/100mL
SprayTopical.36 mg/60mL
StickTopical.5 g/100g
CreamTopical.0125 mg/25g
CreamTopical.004 mg/20mL
CreamTopical.0042 mg/21mL
SoapTopical.05 g/100g
CreamTopical5 mg/100mL
LotionTopical.5 mL/100mL
CreamTopical5 mg/mL
CreamTopical.005 mg/g
CreamTopical1.5 g/300g
LiquidTopical.48 mg/80mL
SolutionTopical.48 mg/80mL
CreamTopical.2 g/100mL
EmulsionTopical.02 g/100mL
CreamTopical.02 g/100mL
LiquidTopical.02 g/100mL
CreamTopical10 mg/g
SoapCutaneous5 mg/g
LiquidTopical
LotionTopical.1 g/100g
EmulsionTopical0.55 %
CreamTopical.28 mg/40mL
KitTopical
CreamTopical1 %
ConcentrateTopical.22 g/45mL
LiquidTopical.075 g/15mL
LiquidTopical.002 mg/mL
CreamTopical.000003 g/30mL
Kit
CreamTopical.002 g/g
LiquidTopical5 mg/mL
LiquidTopical.5 g/100g
SolutionTopical1.9 mg/380mL
CreamTopical.65 mg/130mL
CreamTopical.15 mg/30mL
CreamTopical.75 mg/150mL
CreamTopical.1 mL/100mL
CreamTopical.0075 g/25g
LiquidTopical.5 g/100mL
LiquidTopical.02 g/4mL
LiquidTopical.625 mg/125mL
PatchTopical
CreamTopical0.51 %
PowderTopical.3 mg/3g
PowderTopical
PowderTopical.003 g/3g
PowderTopical.2 mg/2g
LiquidTopical.001 g/mL
LiquidTopical.1 mg/mL
MouthwashDental
Gel, dentifriceDental
CreamTopical.0005 g/g
PowderTopical.0001 g/g
CreamTopical.425 g/85mL
CreamTopical.02 mg/mL
GelTopical5.5 g/L
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Taxonomy

Classification
Not classified

Drug created on December 03, 2015 09:51 / Updated on October 21, 2017 09:35