Boron

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Boron
Accession Number
DB11203
Type
Small Molecule
Groups
Experimental
Description

Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in the periodic table. It is a low-abundant metalloid that is a poor electrical conductor at room temperature. Natural boron exists in 2 stable isotopes however pure boron is hard to prepare due to contamination by different elements. It is also found for applications including ceramics, high-hardness or abrasive compounds, metal coatings, detergents, bleaching agents, insecticides, semiconductors, magnets, wood preservatives, and an additive in glass fibers of boron-containing fiberglass for insulation and structural materials. Boric acid contains antiseptic, antifungal, and antiviral properties thus it is used as a water clarifier in swimming pool water treatment. There are few pharmaceutical agents that contain a boron molecule in their structures, such as Tavaborole and Bortezomib.

Structure
Thumb
Synonyms
  • Bor
  • Boracium
  • Bore
  • Boro
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Calcemin SilverBoron (2.6 mg/1) + Magnesium oxide (40 mg/1) + Zinc oxide (7.5 mg/1)Tablet, film coatedOralBayer HealthCare2016-04-01Not applicableUs
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Calcium Folic Acid Plus D ChewableBoron (250 ug/1) + Calcium Carbonate (1342 mg/1) + Cholecalciferol (300 [iU]/1) + Cyanocobalamin (125 ug/1) + Folic acid (1 mg/1) + Magnesium (50 mg/1) + Pyridoxine (10 mg/1)WaferOralAcella Pharmaceuticals, LLC2009-03-20Not applicableUs
Neonatal Plus VitaminBoron (0.2 mg/1) + Ascorbic acid (20 mg/1) + Calcium (200 mg/1) + Cholecalciferol (10 ug/1) + Citrus bioflavonoids (2 mg/1) + Copper (2 mg/1) + Cyanocobalamin (12 ug/1) + Ferrous fumarate (27 mg/1) + Folic acid (1000 ug/1) + Inositol (5 mg/1) + Nicotinamide (20 mg/1) + Pyridoxine hydrochloride (10 mg/1) + Riboflavin (3 mg/1) + Thiamine chloride (1.84 mg/1) + Vitamin A (1200 ug/1) + Zinc oxide (25 mg/1) + alpha-Tocopherol acetate (9.2 mg/1)TabletOralNeomed Pharmaceutical2018-07-31Not applicableUs
Prenate ChewableBoron (250 ug/1) + Bilberry (25 mg/1) + Biotin (280 ug/1) + Calcium Carbonate (500 mg/1) + Cholecalciferol (300 [iU]/1) + Cyanocobalamin (125 mg/1) + Folic acid (1 mg/1) + Magnesium oxide (50 mg/1) + Pyridoxine hydrochloride (10 mg/1)Tablet, chewableOralAvion Pharmaceuticals, Llc2013-02-28Not applicableUs
Categories
UNII
N9E3X5056Q
CAS number
7440-42-8
Weight
Average: 10.81
Monoisotopic: 11.009305
Chemical Formula
B
InChI Key
ZOXJGFHDIHLPTG-UHFFFAOYSA-N
InChI
InChI=1S/B
IUPAC Name
boranylidyne
SMILES
[B]

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
PubChem Compound
5462311
PubChem Substance
347827941
ChemSpider
4575371
ChEBI
27560
Wikipedia
Boron

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
1Unknown StatusTreatmentDiabetic Foot Ulcers (DFU)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
Tablet, film coatedOral
WaferOral
TabletOral
Tablet, chewableOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0.33ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of inorganic compounds known as homogeneous metalloid compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a metalloid atom.
Kingdom
Inorganic compounds
Super Class
Homogeneous metal compounds
Class
Homogeneous metalloid compounds
Sub Class
Not Available
Direct Parent
Homogeneous metalloid compounds
Alternative Parents
Not Available
Substituents
Homogeneous metalloid
Molecular Framework
Not Available
External Descriptors
boron group element atom, nonmetal atom (CHEBI:27560)

Drug created on December 03, 2015 09:51 / Updated on June 04, 2019 07:17